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Volumn 7, Issue , 2017, Pages

Extracellular proteasome-osteopontin circuit regulates cell migration with implications in multiple sclerosis

(26)  Dianzani, Chiara a   Bellavista, Elena b   Liepe, Juliane c   Verderio, Claudia d,e   Martucci, Morena b   Santoro, Aurelia b   Chiocchetti, Annalisa f   Gigliotti, Casimiro Luca f   Boggio, Elena f   Ferrara, Benedetta a   Riganti, Loredana d   Keller, Christin g,h   Janek, Katharina g   Niewienda, Agathe g   Fenoglio, Chiara i   Sorosina, Melissa j   Cantello, Roberto f   Kloetzel, Peter M g,h   Stumpf, Michael P H c   Paul, Friedemann g,k   more..

d CNR   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

OSTEOPONTIN; PROTEASOME;

EID: 85014904136     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep43718     Document Type: Article
Times cited : (34)

References (42)
  • 1
    • 84896903104 scopus 로고    scopus 로고
    • Immunology of relapse and remission in multiple sclerosis
    • Steinman L. Immunology of relapse and remission in multiple sclerosis. Annu Rev Immunol 32, 257-281 (2014
    • (2014) Annu Rev Immunol , vol.32 , pp. 257-281
    • Steinman, L.1
  • 2
    • 67349213676 scopus 로고    scopus 로고
    • A molecular trio in relapse and remission in multiple sclerosis
    • Steinman L. A molecular trio in relapse and remission in multiple sclerosis. Nat Rev Immunol 9, 440-447 (2009
    • (2009) Nat Rev Immunol , vol.9 , pp. 440-447
    • Steinman, L.1
  • 3
    • 39049136065 scopus 로고    scopus 로고
    • Specificity And correlation with disease activity of cerebrospinal fluid osteopontin levels in patients with multiple sclerosis
    • Chowdhury S. A, Lin J, & Sadiq S. A. Specificity and correlation with disease activity of cerebrospinal fluid osteopontin levels in patients with multiple sclerosis. Arch Neurol 65, 232-235 (2008
    • (2008) Arch Neurol , vol.65 , pp. 232-235
    • Chowdhury, S.A.1    Lin, J.2    Sadiq, S.A.3
  • 4
    • 21044457664 scopus 로고    scopus 로고
    • Osteopontin gene haplotypes correlate with multiple sclerosis development and progression
    • Chiocchetti A, et al. Osteopontin gene haplotypes correlate with multiple sclerosis development and progression. J Neuroimmunol 163, 172-178 (2005
    • (2005) J Neuroimmunol , vol.163 , pp. 172-178
    • Chiocchetti, A.1
  • 5
    • 10344246601 scopus 로고    scopus 로고
    • Plasma osteopontin levels in multiple sclerosis
    • Comabella M, et al. Plasma osteopontin levels in multiple sclerosis. J Neuroimmunol 158, 231-239 (2005
    • (2005) J Neuroimmunol , vol.158 , pp. 231-239
    • Comabella, M.1
  • 6
    • 33846998653 scopus 로고    scopus 로고
    • Osteopontin-induced relapse and progression of autoimmune brain disease through enhanced survival of activated T cells
    • Hur E. M, et al. Osteopontin-induced relapse and progression of autoimmune brain disease through enhanced survival of activated T cells. Nat Immunol 8, 74-83 (2007
    • (2007) Nat Immunol , vol.8 , pp. 74-83
    • Hur, E.M.1
  • 7
    • 84907437823 scopus 로고    scopus 로고
    • Thrombin cleavage of osteopontin disrupts a pro-chemotactic sequence for dendritic cells, which is compensated by the release of its pro-chemotactic C-Terminal fragment
    • Shao Z, Morser J, & Leung L. L. Thrombin cleavage of osteopontin disrupts a pro-chemotactic sequence for dendritic cells, which is compensated by the release of its pro-chemotactic C-Terminal fragment. J Biol Chem 289, 27146-27158 (2014
    • (2014) J Biol Chem , vol.289 , pp. 27146-27158
    • Shao, Z.1    Morser, J.2    Leung, L.L.3
  • 8
    • 84979790726 scopus 로고    scopus 로고
    • Thrombin cleavage of osteopontin modulates its activities in human cells in vitro and mouse experimental autoimmune encephalomyelitis in vivo
    • Boggio E, et al. Thrombin Cleavage of Osteopontin Modulates Its Activities in Human Cells In Vitro and Mouse Experimental Autoimmune Encephalomyelitis In Vivo. J Immunol Res 2016, 9345495, doi: 10.1155/2016/9345495 (2016
    • (2016) J Immunol Res , vol.2016 , pp. 9345495
    • Boggio, E.1
  • 9
    • 72949103056 scopus 로고    scopus 로고
    • Proteasomes in immune cells: More than peptide producers?
    • Groettrup M, Kirk C. J, & Basler M. Proteasomes in immune cells: more than peptide producers?. Nat Rev Immunol 10, 73-78 (2010
    • (2010) Nat Rev Immunol , vol.10 , pp. 73-78
    • Groettrup, M.1    Kirk, C.J.2    Basler, M.3
  • 10
    • 84944788684 scopus 로고    scopus 로고
    • Quantitative time-resolved analysis reveals intricate, differential regulation of standard- and immuno-proteasomes
    • Liepe J, et al. Quantitative time-resolved analysis reveals intricate, differential regulation of standard- And immuno-proteasomes. Elife 4 (2015
    • (2015) Elife , vol.4
    • Liepe, J.1
  • 11
    • 84903702716 scopus 로고    scopus 로고
    • Differential global structural changes in the core particle of yeast and mouse proteasome induced by ligand binding
    • Arciniega M, Beck P, Lange O. F, Groll M, & Huber R. Differential global structural changes in the core particle of yeast and mouse proteasome induced by ligand binding. Proc Natl Acad Sci USA 111, 9479-9484 (2014
    • (2014) Proc Natl Acad Sci USA , vol.111 , pp. 9479-9484
    • Arciniega, M.1    Beck, P.2    Lange, O.F.3    Groll, M.4    Huber, R.5
  • 12
    • 84924325954 scopus 로고    scopus 로고
    • Proteasome isoforms exhibit only quantitative differences in cleavage and epitope generation
    • Mishto M, et al. Proteasome isoforms exhibit only quantitative differences in cleavage and epitope generation. Eur J Immunol 44, 3508-3521 (2014
    • (2014) Eur J Immunol , vol.44 , pp. 3508-3521
    • Mishto, M.1
  • 13
    • 56449112645 scopus 로고    scopus 로고
    • Extracellular, circulating proteasomes and ubiquitin - Incidence and relevance
    • Sixt S. U, & Dahlmann B. Extracellular, circulating proteasomes and ubiquitin - incidence and relevance. Biochim Biophys Acta 1782, 817-823 (2008
    • (2008) Biochim Biophys Acta , vol.1782 , pp. 817-823
    • Sixt, S.U.1    Dahlmann, B.2
  • 14
    • 33750476672 scopus 로고    scopus 로고
    • Circulating proteasomes are functional and have a subtype pattern distinct from 20S proteasomes in major blood cells
    • Zoeger A, Blau M, Egerer K, Feist E, & Dahlmann B. Circulating proteasomes are functional and have a subtype pattern distinct from 20S proteasomes in major blood cells. Clin Chem 52, 2079-2086 (2006
    • (2006) Clin Chem , vol.52 , pp. 2079-2086
    • Zoeger, A.1    Blau, M.2    Egerer, K.3    Feist, E.4    Dahlmann, B.5
  • 15
    • 20444477186 scopus 로고    scopus 로고
    • Heightened levels of circulating 20S proteasome in critically ill patients
    • Roth G. A, et al. Heightened levels of circulating 20S proteasome in critically ill patients. Eur J Clin Invest 35, 399-403 (2005
    • (2005) Eur J Clin Invest , vol.35 , pp. 399-403
    • Roth, G.A.1
  • 16
    • 84891373742 scopus 로고    scopus 로고
    • T lymphocytes export proteasomes by way of microparticles: A possible mechanism for generation of extracellular proteasomes
    • Bochmann I, et al. T lymphocytes export proteasomes by way of microparticles: a possible mechanism for generation of extracellular proteasomes. J Cell Mol Med 18, 59-68 (2014
    • (2014) J Cell Mol Med , vol.18 , pp. 59-68
    • Bochmann, I.1
  • 17
    • 84866524463 scopus 로고    scopus 로고
    • Proteolytic potential of the msc exosome proteome: Implications for an exosome-mediated delivery of therapeutic proteasome
    • Lai R. C, et al. Proteolytic Potential of the MSC Exosome Proteome: Implications for an Exosome-Mediated Delivery of Therapeutic Proteasome. Int J Proteomics 2012, 971907 (2012
    • (2012) Int J Proteomics , vol.2012 , pp. 971907
    • Lai, R.C.1
  • 18
    • 66649115349 scopus 로고    scopus 로고
    • Plasma proteasome level is a reliable early marker of malignant transformation of liver cirrhosis
    • Henry L, et al. Plasma proteasome level is a reliable early marker of malignant transformation of liver cirrhosis. Gut 58, 833-838 (2009
    • (2009) Gut , vol.58 , pp. 833-838
    • Henry, L.1
  • 19
    • 84876681536 scopus 로고    scopus 로고
    • Clinical use of p-proteasome in discriminating metastatic melanoma patients: Comparative study with LDH, MIA and S100B protein
    • Henry L, et al. Clinical use of p-proteasome in discriminating metastatic melanoma patients: comparative study with LDH, MIA and S100B protein. Int J Cancer 133, 142-148 (2013
    • (2013) Int J Cancer , vol.133 , pp. 142-148
    • Henry, L.1
  • 20
    • 84857787712 scopus 로고    scopus 로고
    • Serum 20S proteasome is elevated in patients with renal cell carcinoma and associated with poor prognosis
    • de Martino M, et al. Serum 20S proteasome is elevated in patients with renal cell carcinoma and associated with poor prognosis. Br J Cancer 106, 904-908 (2012
    • (2012) Br J Cancer , vol.106 , pp. 904-908
    • De Martino, M.1
  • 21
    • 0036790834 scopus 로고    scopus 로고
    • Circulating proteasomes are markers of cell damage and immunologic activity in autoimmune diseases
    • Egerer K, et al. Circulating proteasomes are markers of cell damage and immunologic activity in autoimmune diseases. J Rheumatol 29, 2045-2052 (2002
    • (2002) J Rheumatol , vol.29 , pp. 2045-2052
    • Egerer, K.1
  • 22
    • 84864106711 scopus 로고    scopus 로고
    • Plasma ubiquitin-proteasome system profile in patients with multiple sclerosis: Correlation with clinical features, neuroimaging, and treatment with interferon-beta-1b
    • Minagar A, et al. Plasma ubiquitin-proteasome system profile in patients with multiple sclerosis: correlation with clinical features, neuroimaging, and treatment with interferon-beta-1b. Neurol Res 34, 611-618 (2012
    • (2012) Neurol Res , vol.34 , pp. 611-618
    • Minagar, A.1
  • 23
  • 24
    • 84859155913 scopus 로고    scopus 로고
    • Circulating extracellular proteasome in the cerebrospinal fluid: A study on concentration and proteolytic activity
    • Mueller O, et al. Circulating extracellular proteasome in the cerebrospinal fluid: a study on concentration and proteolytic activity. J Mol Neurosci 46, 509-515 (2011
    • (2011) J Mol Neurosci , vol.46 , pp. 509-515
    • Mueller, O.1
  • 25
    • 85013222187 scopus 로고    scopus 로고
    • Standardization of sample collection, isolation and analysis methods in extracellular vesicle research
    • Witwer K. W, et al. Standardization of sample collection, isolation and analysis methods in extracellular vesicle research. J Extracell Vesicles 2 (2013
    • (2013) J Extracell Vesicles , vol.2
    • Witwer, K.W.1
  • 26
    • 84992027493 scopus 로고    scopus 로고
    • A large fraction of HLA class i ligands are proteasome-generated spliced peptides
    • Liepe J, et al. A large fraction of HLA class I ligands are proteasome-generated spliced peptides. Science 354, 354-358 (2016
    • (2016) Science , vol.354 , pp. 354-358
    • Liepe, J.1
  • 27
    • 84963682507 scopus 로고    scopus 로고
    • Proteasomes generate spliced epitopes by two different mechanisms and as efficiently as non-spliced epitopes
    • Ebstein F, et al. Proteasomes generate spliced epitopes by two different mechanisms and as efficiently as non-spliced epitopes. Sci Rep 6, 24032 (2016
    • (2016) Sci Rep , vol.6 , pp. 24032
    • Ebstein, F.1
  • 28
    • 84867173683 scopus 로고    scopus 로고
    • Driving forces of proteasome-catalyzed peptide splicing in yeast and humans
    • Mishto M, et al. Driving Forces of Proteasome-catalyzed Peptide Splicing in Yeast and Humans. Mol Cell Proteomics 11, 1008-1023 (2012
    • (2012) Mol Cell Proteomics , vol.11 , pp. 1008-1023
    • Mishto, M.1
  • 29
    • 84893204344 scopus 로고    scopus 로고
    • Current understanding on the role of standard and immunoproteasomes in inflammatory/immunological pathways of multiple sclerosis
    • Bellavista E, et al. Current understanding on the role of standard and immunoproteasomes in inflammatory/immunological pathways of multiple sclerosis. Autoimmune Dis 2014, 739705 (2014
    • (2014) Autoimmune Dis , vol.2014 , pp. 739705
    • Bellavista, E.1
  • 30
    • 84876702879 scopus 로고    scopus 로고
    • Immunoproteasome in cancer and neuropathologies: A new therapeutic target?
    • Bellavista E, et al. Immunoproteasome in cancer and neuropathologies: a new therapeutic target?. Curr Pharm Des 19, 702-718 (2013
    • (2013) Curr Pharm des , vol.19 , pp. 702-718
    • Bellavista, E.1
  • 31
    • 84867324545 scopus 로고    scopus 로고
    • Immunoproteasome subunit LMP7 deficiency and inhibition suppresses Th1 and Th17 but enhances regulatory T cell differentiation
    • Kalim K. W, Basler M, Kirk C. J, & Groettrup M. Immunoproteasome subunit LMP7 deficiency and inhibition suppresses Th1 and Th17 but enhances regulatory T cell differentiation. J Immunol 189, 4182-4193 (2012
    • (2012) J Immunol , vol.189 , pp. 4182-4193
    • Kalim, K.W.1    Basler, M.2    Kirk, C.J.3    Groettrup, M.4
  • 32
    • 67650388103 scopus 로고    scopus 로고
    • A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis
    • Muchamuel T, et al. A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis. Nat Med 15, 781-787 (2009
    • (2009) Nat Med , vol.15 , pp. 781-787
    • Muchamuel, T.1
  • 33
    • 84893771480 scopus 로고    scopus 로고
    • Inhibition of the immunoproteasome ameliorates experimental autoimmune encephalomyelitis
    • Basler M, et al. Inhibition of the immunoproteasome ameliorates experimental autoimmune encephalomyelitis. EMBO Mol Med 6, 226-238 (2014
    • (2014) EMBO Mol Med , vol.6 , pp. 226-238
    • Basler, M.1
  • 34
    • 84924325954 scopus 로고    scopus 로고
    • Proteasome isoforms exhibit only quantitative differences in cleavage and epitope generation
    • Mishto M, et al. Proteasome isoforms exhibit only quantitative differences in cleavage and epitope generation. Eur J Immunol (2014
    • (2014) Eur J Immunol
    • Mishto, M.1
  • 35
    • 77955505159 scopus 로고    scopus 로고
    • The 20s proteasome splicing activity discovered by splicemet
    • Liepe J, et al. The 20S Proteasome Splicing Activity Discovered by SpliceMet. PLOS Computational Biology 6, e1000830 (2010
    • (2010) PLOS Computational Biology , vol.6 , pp. e1000830
    • Liepe, J.1
  • 36
    • 84925156346 scopus 로고    scopus 로고
    • The I-TASSER Suite: Protein structure and function prediction
    • Yang J, et al. The I-TASSER Suite: protein structure and function prediction. Nat Methods 12, 7-8 (2015
    • (2015) Nat Methods , vol.12 , pp. 7-8
    • Yang, J.1
  • 37
    • 84908114976 scopus 로고    scopus 로고
    • Tertiary structure prediction and identification of druggable pocket in the cancer biomarker -Osteopontin-c
    • Sivakumar S, & Niranjali Devaraj S. Tertiary structure prediction and identification of druggable pocket in the cancer biomarker -Osteopontin-c. J Diabetes Metab Disord 13, 13 (2014
    • (2014) J Diabetes Metab Disord , vol.13 , pp. 13
    • Sivakumar, S.1    Niranjali Devaraj, S.2
  • 38
    • 79952501096 scopus 로고    scopus 로고
    • Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria
    • Polman C. H, et al. Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria. Ann Neurol 69, 292-302 (2011
    • (2011) Ann Neurol , vol.69 , pp. 292-302
    • Polman, C.H.1
  • 39
    • 84906790427 scopus 로고    scopus 로고
    • Osteopontin circulating levels correlate with renal involvement in systemic lupus erythematosus and are lower in ACE inhibitor-Treated patients
    • Quaglia M, et al. Osteopontin circulating levels correlate with renal involvement in systemic lupus erythematosus and are lower in ACE inhibitor-Treated patients. Clin Rheumatol 33, 1263-1271 (2014
    • (2014) Clin Rheumatol , vol.33 , pp. 1263-1271
    • Quaglia, M.1
  • 40
    • 79251596822 scopus 로고    scopus 로고
    • The prognostic impact of circulating proteasome concentrations in patients with epithelial ovarian cancer
    • Heubner M, et al. The prognostic impact of circulating proteasome concentrations in patients with epithelial ovarian cancer. Gynecol Oncol 120, 233-238 (2011
    • (2011) Gynecol Oncol , vol.120 , pp. 233-238
    • Heubner, M.1
  • 41
    • 67349114201 scopus 로고    scopus 로고
    • Acid sphingomyelinase activity triggers microparticle release from glial cells
    • Bianco F, et al. Acid sphingomyelinase activity triggers microparticle release from glial cells. Embo J 28, 1043-1054 (2009
    • (2009) Embo J , vol.28 , pp. 1043-1054
    • Bianco, F.1
  • 42
    • 33645788632 scopus 로고    scopus 로고
    • A structural model of 20S immunoproteasomes: Effect of LMP2 codon 60 polymorphism on expression, activity, intracellular localisation and insight into the regulatory mechanisms
    • Mishto M, et al. A structural model of 20S immunoproteasomes: effect of LMP2 codon 60 polymorphism on expression, activity, intracellular localisation and insight into the regulatory mechanisms. Biol Chem 387, 417-429 (2006
    • (2006) Biol Chem , vol.387 , pp. 417-429
    • Mishto, M.1


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