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Volumn 42, Issue 2, 2017, Pages 179-186

Nepeta Dschuparensis Bornm extract moderates COX-2 and IL-1β proteins in a rat model of cerebral ischemia

Author keywords

Brain antioxidants; Cyclooxygenase 2; Hypoxia ischemia; Interleukin 1beta; Nepeta

Indexed keywords

CYCLOOXYGENASE 2; INTERLEUKIN 1BETA; NEPETA DSCHUPARENSIS EXTRACT; NEUROPROTECTIVE AGENT; PLANT EXTRACT; TRIPHENYLTETRAZOLIUM; UNCLASSIFIED DRUG;

EID: 85014774804     PISSN: 02530716     EISSN: 17353688     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (10)

References (34)
  • 1
    • 71049180369 scopus 로고    scopus 로고
    • Inflammatory mechanisms in ischemic stroke: Therapeutic approaches
    • 19919699, PMC2780998
    • Lakhan SE, Kirchgessner A, Hofer M. Inflammatory mechanisms in ischemic stroke: Therapeutic approaches. J Transl Med. 2009;7:97. doi: 10.1186/1479-5876-7-97. PubMed PMID: 19919699; PubMed Central PMCID: PMC2780998.
    • (2009) J Transl Med , vol.7 , pp. 97
    • Lakhan, S.E.1    Kirchgessner, A.2    Hofer, M.3
  • 2
    • 39049169272 scopus 로고    scopus 로고
    • Modulation of neuro-inflammation and vascular response by oxidative stress following cerebral ischemia-reperfusion injury
    • 18220759
    • Wong CH, Crack PJ. Modulation of neuro-inflammation and vascular response by oxidative stress following cerebral ischemia-reperfusion injury. Curr Med Chem. 2008;15:1-14. doi: 10.2174/092986708783330665. PubMed PMID: 18220759.
    • (2008) Curr Med Chem , vol.15 , pp. 1-14
    • Wong, C.H.1    Crack, P.J.2
  • 3
    • 0037312886 scopus 로고    scopus 로고
    • Inflammatory mechanisms after ischemia and stroke
    • 12578222
    • Danton GH, Dietrich WD. Inflammatory mechanisms after ischemia and stroke. J Neuropathol Exp Neurol. 2003;62:127-36. doi: 10.1093/jnen/62.2.127. PubMed PMID: 12578222.
    • (2003) J Neuropathol Exp Neurol , vol.62 , pp. 127-136
    • Danton, G.H.1    Dietrich, W.D.2
  • 4
    • 62949176283 scopus 로고    scopus 로고
    • The distinct roles of cyclooxygenase-1 and -2 in neuroinflammation: Implications for translational research
    • 19269697, PMC3379810
    • Choi SH, Aid S, Bosetti F. The distinct roles of cyclooxygenase-1 and -2 in neuroinflammation: Implications for translational research. Trends Pharmacol Sci. 2009;30:174-81. doi: 10.1016/j.tips.2009.01.002. PubMed PMID: 19269697; PubMed Central PMCID: PMC3379810.
    • (2009) Trends Pharmacol Sci , vol.30 , pp. 174-181
    • Choi, S.H.1    Aid, S.2    Bosetti, F.3
  • 5
    • 47249129136 scopus 로고    scopus 로고
    • Cyclooxygenase-2 in synaptic signaling
    • 18537667, PMC2561288
    • Yang H, Chen C. Cyclooxygenase-2 in synaptic signaling. Curr Pharm Des. 2008;14:1443-51. doi: 10.2174/138161208784480144. PubMed PMID: 18537667; PubMed Central PMCID: PMC2561288.
    • (2008) Curr Pharm Des , vol.14 , pp. 1443-1451
    • Yang, H.1    Chen, C.2
  • 6
    • 47249106478 scopus 로고    scopus 로고
    • Cyclooxygenase inhibition in ischemic brain injury
    • 18537663
    • Candelario-Jalil E, Fiebich BL. Cyclooxygenase inhibition in ischemic brain injury. Curr Pharm Des. 2008;14:1401-18. doi: 10.2174/138161208784480216. PubMed PMID: 18537663.
    • (2008) Curr Pharm Des , vol.14 , pp. 1401-1418
    • Candelario-Jalil, E.1    Fiebich, B.L.2
  • 7
    • 4744352557 scopus 로고    scopus 로고
    • Interleukin-1: A master regulator of neuroinflammation
    • 15378607
    • Basu A, Krady JK, Levison SW. Interleukin-1: A master regulator of neuroinflammation. J Neurosci Res. 2004;78:151-6. doi: 10.1002/jnr.20266. PubMed PMID: 15378607.
    • (2004) J Neurosci Res , vol.78 , pp. 151-156
    • Basu, A.1    Krady, J.K.2    Levison, S.W.3
  • 8
    • 0037410074 scopus 로고    scopus 로고
    • Interleukin-1 and neuronal injury: Mechanisms, modification, and therapeutic potential
    • 12706413
    • Rothwell N. Interleukin-1 and neuronal injury: Mechanisms, modification, and therapeutic potential. Brain Behav Immun. 2003;17:152-7. doi: 10.1016/S0889-1591(02)00098-3. PubMed PMID: 12706413.
    • (2003) Brain Behav Immun , vol.17 , pp. 152-157
    • Rothwell, N.1
  • 9
    • 0035278914 scopus 로고    scopus 로고
    • Cytokines and the central nervous system
    • 11306183
    • Szelényi J. Cytokines and the central nervous system. Brain Res Bull. Brain Res Bull. 2001;54:329-38. doi: 10.1016/S0361-9230(01)00428-2. PubMed PMID: 11306183.
    • (2001) Brain Res Bull. Brain Res Bull , vol.54 , pp. 329-338
    • Szelényi, J.1
  • 10
    • 0037883283 scopus 로고    scopus 로고
    • Leaf surface flavonoids in Iranian species of Nepeta (Lamiaceae) and some related genera
    • Jamzad Z, Grayer RJ, Kite GC, Simmonds MS, Ingrouille M, Jalili A. Leaf surface flavonoids in Iranian species of Nepeta (Lamiaceae) and some related genera. Biochem Syst Ecol. 2003;31:587-600. doi: 10.1016/S0305-1978(02)00221-1.
    • (2003) Biochem Syst Ecol , vol.31 , pp. 587-600
    • Jamzad, Z.1    Grayer, R.J.2    Kite, G.C.3    Simmonds, M.S.4    Ingrouille, M.5    Jalili, A.6
  • 11
    • 0024494427 scopus 로고
    • Reversible middle cerebral artery occlusion without craniectomy in rats
    • 2643202
    • Longa EZ, Weinstein PR, Carlson S, Cummins R. Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke. 1989;20:84-91. doi: 10.1161/01. STR.20.1.84. PubMed PMID: 2643202.
    • (1989) Stroke , vol.20 , pp. 84-91
    • Longa, E.Z.1    Weinstein, P.R.2    Carlson, S.3    Cummins, R.4
  • 12
    • 84876136497 scopus 로고    scopus 로고
    • Neuroprotective effects of the immunomodulatory drug Setarud on cerebral ischemia in male rats
    • 25558220, PMC4281408
    • Vafaee F, Zangiabadi N, Pour FM, Dehghanian F, Asadi-Shekaari M, Afshar HK. Neuroprotective effects of the immunomodulatory drug Setarud on cerebral ischemia in male rats. Neural Regen Res. 2012;7:2085-91. doi: 10.3969/j.issn.1673-5374.2012.27.001. PubMed PMID: 25558220; PubMed Central PMCID: PMC4281408.
    • (2012) Neural Regen Res , vol.7 , pp. 2085-2091
    • Vafaee, F.1    Zangiabadi, N.2    Pour, F.M.3    Dehghanian, F.4    Asadi-Shekaari, M.5    Afshar, H.K.6
  • 13
    • 84862333850 scopus 로고    scopus 로고
    • Cerebroprotective effect of date seed extract (Phoenix dactylifera) on focal cerebral ischemia in male rats
    • Kalantaripour T, Asadi-Shekaari M, Basiri M, Najar AG. Cerebroprotective effect of date seed extract (Phoenix dactylifera) on focal cerebral ischemia in male rats. J Biol Sci. 2012;12:180. doi: 10.3923/jbs.2012.180.185.
    • (2012) J Biol Sci , vol.12 , pp. 180
    • Kalantaripour, T.1    Asadi-Shekaari, M.2    Basiri, M.3    Najar, A.G.4
  • 14
    • 59649123881 scopus 로고    scopus 로고
    • Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke
    • 19169263
    • Liesz A, Suri-Payer E, Veltkamp C, Doerr H, Sommer C, Rivest S, et al. Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke. Nat Med. 2009;15:192-9. doi: 10.1038/nm.1927. PubMed PMID: 19169263.
    • (2009) Nat Med , vol.15 , pp. 192-199
    • Liesz, A.1    Suri-Payer, E.2    Veltkamp, C.3    Doerr, H.4    Sommer, C.5    Rivest, S.6
  • 15
    • 49849103054 scopus 로고    scopus 로고
    • Ischemic postconditioning inhibits apoptosis after focal cerebral ischemia/reperfusion injury in the rat
    • 18583563
    • Xing B, Chen H, Zhang M, Zhao D, Jiang R, Liu X, et al. Ischemic postconditioning inhibits apoptosis after focal cerebral ischemia/reperfusion injury in the rat. Stroke. 2008;39:2362-9. doi: 10.1161/STROKEAHA.107.507939. PubMed PMID: 18583563.
    • (2008) Stroke , vol.39 , pp. 2362-2369
    • Xing, B.1    Chen, H.2    Zhang, M.3    Zhao, D.4    Jiang, R.5    Liu, X.6
  • 16
    • 0030716503 scopus 로고    scopus 로고
    • Superior neuroprotective efficacy of a novel antioxidant (U-101033E) with improved blood-brain barrier permeability in focal cerebral ischemia
    • 9341713
    • Schmid-Elsaesser R, Zausinger S, Hungerhuber E, Plesnila N, Baethmann A, Reulen HJ. Superior neuroprotective efficacy of a novel antioxidant (U-101033E) with improved blood-brain barrier permeability in focal cerebral ischemia. Stroke. 1997;28:2018-24. doi: 10.1161/01.STR.28.10.2018. PubMed PMID: 9341713.
    • (1997) Stroke , vol.28 , pp. 2018-2024
    • Schmid-Elsaesser, R.1    Zausinger, S.2    Hungerhuber, E.3    Plesnila, N.4    Baethmann, A.5    Reulen, H.J.6
  • 17
    • 80052025635 scopus 로고    scopus 로고
    • Protective effect of Etoricoxib against middle cerebral artery occlusion induced transient focal cerebral ischemia in rats
    • 21635885
    • Maheshwari A, Badgujar L, Phukan B, Bodhankar SL, Thakurdesai P. Protective effect of Etoricoxib against middle cerebral artery occlusion induced transient focal cerebral ischemia in rats. Eur J Pharmacol. 2011;667:230-7. doi: 10.1016/j.ejphar.2011.05.030. PubMed PMID: 21635885.
    • (2011) Eur J Pharmacol , vol.667 , pp. 230-237
    • Maheshwari, A.1    Badgujar, L.2    Phukan, B.3    Bodhankar, S.L.4    Thakurdesai, P.5
  • 18
    • 0034724791 scopus 로고    scopus 로고
    • Neurological impairment in rats after transient middle cerebral artery occlusion: A comparative study under various treatment paradigms
    • 10773197
    • Zausinger S, Hungerhuber E, Baethmann A, Reulen H, Schmid-Elsaesser R. Neurological impairment in rats after transient middle cerebral artery occlusion: A comparative study under various treatment paradigms. Brain Res. 2000;863:94-105. doi: 10.1016/S0006-8993(00)02100-4. PubMed PMID: 10773197.
    • (2000) Brain Res , vol.863 , pp. 94-105
    • Zausinger, S.1    Hungerhuber, E.2    Baethmann, A.3    Reulen, H.4    Schmid-Elsaesser, R.5
  • 19
    • 0037199090 scopus 로고    scopus 로고
    • A test for detecting long-term sensorimotor dysfunction in the mouse after focal cerebral ischemia
    • 12100987
    • Zhang L, Schallert T, Zhang ZG, Jiang Q, Arniego P, Li Q, et al. A test for detecting long-term sensorimotor dysfunction in the mouse after focal cerebral ischemia. J Neurosci Methods. 2002;117:207-14. doi: 10.1016/S0165-0270(02)00114-0. PubMed PMID: 12100987.
    • (2002) J Neurosci Methods , vol.117 , pp. 207-214
    • Zhang, L.1    Schallert, T.2    Zhang, Z.G.3    Jiang, Q.4    Arniego, P.5    Li, Q.6
  • 20
    • 0037099784 scopus 로고    scopus 로고
    • Caspase inhibition by Z-VAD increases the survival of grafted bone marrow cells and improves functional outcome after MCAo in rats
    • 12084437
    • Chen J, Li Y, Wang L, Lu M, Chopp M. Caspase inhibition by Z-VAD increases the survival of grafted bone marrow cells and improves functional outcome after MCAo in rats. J Neurol Sci. 2002;199:17-24. doi: 10.1016/S0022-510X(02)00075-8. PubMed PMID: 12084437.
    • (2002) J Neurol Sci , vol.199 , pp. 17-24
    • Chen, J.1    Li, Y.2    Wang, L.3    Lu, M.4    Chopp, M.5
  • 21
    • 8744309183 scopus 로고    scopus 로고
    • Chronic ethanol treatment enhances inflammatory mediators and cell death in the brain and in astrocytes
    • 15605983
    • Vallés SL, Blanco AM, Pascual M, Guerri C. Chronic ethanol treatment enhances inflammatory mediators and cell death in the brain and in astrocytes. Brain Pathol. 2004;14:365-71. doi: 10.1111/j.1750-3639.2004.tb00079.x. PubMed PMID: 15605983.
    • (2004) Brain Pathol , vol.14 , pp. 365-371
    • Vallés, S.L.1    Blanco, A.M.2    Pascual, M.3    Guerri, C.4
  • 22
    • 4444333049 scopus 로고    scopus 로고
    • Cyclooxygenase-2 (COX-2) in inflammatory and degenerative brain diseases
    • 15453089
    • Minghetti L. Cyclooxygenase-2 (COX-2) in inflammatory and degenerative brain diseases. J Neuropathol Exp Neurol. 2004;63:901-10. doi: 10.1093/jnen/63.9.901. PubMed PMID: 15453089.
    • (2004) J Neuropathol Exp Neurol , vol.63 , pp. 901-910
    • Minghetti, L.1
  • 23
    • 30444459031 scopus 로고    scopus 로고
    • The role of inflammation in CNS injury and disease
    • 16402109, PMC1760754
    • Lucas SM, Rothwell NJ, Gibson RM. The role of inflammation in CNS injury and disease. Br J Pharmacol. 2006;147 Suppl 1:S232-40. doi: 10.1038/sj.bjp.0706400. PubMed PMID: 16402109; PubMed Central PMCID: PMC1760754.
    • (2006) Br J Pharmacol , vol.147 , pp. S232-S240
    • Lucas, S.M.1    Rothwell, N.J.2    Gibson, R.M.3
  • 24
    • 0035149749 scopus 로고    scopus 로고
    • Reactive oxygen radicals in signaling and damage in the ischemic brain
    • 11149664
    • Chan PH. Reactive oxygen radicals in signaling and damage in the ischemic brain. J Cereb Blood Flow Metab. 2001;21:2-14. doi: 10.1097/00004647-200101000-00002. PubMed PMID: 11149664.
    • (2001) J Cereb Blood Flow Metab , vol.21 , pp. 2-14
    • Chan, P.H.1
  • 25
    • 0035887744 scopus 로고    scopus 로고
    • Age-dependent cognitive deficits and neuronal apoptosis in cyclooxygenase-2 transgenic mice
    • 11588192
    • Andreasson KI, Savonenko A, Vidensky S, Goellner JJ, Zhang Y, Shaffer A, et al. Age-dependent cognitive deficits and neuronal apoptosis in cyclooxygenase-2 transgenic mice.. J Neurosci. 2001;21:8198-209. PubMed PMID: 11588192.
    • (2001) J Neurosci , vol.21 , pp. 8198-8209
    • Andreasson, K.I.1    Savonenko, A.2    Vidensky, S.3    Goellner, J.J.4    Zhang, Y.5    Shaffer, A.6
  • 26
    • 19644364808 scopus 로고    scopus 로고
    • The role of free radicals in cerebral hypoxia and ischemia
    • 15925277
    • Rodrigo J, Fernández AP, Serrano J, Peinado MA, Martínez A. The role of free radicals in cerebral hypoxia and ischemia. Free Radic Biol Med. 2005;39:26-50. doi: 10.1016/j.freeradbiomed.2005.02.010. PubMed PMID: 15925277.
    • (2005) Free Radic Biol Med , vol.39 , pp. 26-50
    • Rodrigo, J.1    Fernández, A.P.2    Serrano, J.3    Peinado, M.A.4    Martínez, A.5
  • 27
    • 33847644971 scopus 로고    scopus 로고
    • The inflammatory response in stroke
    • 17188755, PMC1868538
    • Wang Q, Tang XN, Yenari MA. The inflammatory response in stroke. J Neuroimmunol. 2007;184:53-68. doi: 10.1016/j.jneuroim.2006.11.014. PubMed PMID: 17188755; PubMed Central PMCID: PMC1868538.
    • (2007) J Neuroimmunol , vol.184 , pp. 53-68
    • Wang, Q.1    Tang, X.N.2    Yenari, M.A.3
  • 28
    • 84918838539 scopus 로고    scopus 로고
    • In the pathogenesis of ischemic stroke
    • 25553478
    • Pei J, You X, Fu Q. Inflammation in the pathogenesis of ischemic stroke. Front Biosci (Landmark Ed). 2015;20:772-83. doi: 10.2741/4336.PubMed PMID: 25553478.
    • (2015) Front Biosci (Landmark Ed) , vol.20 , pp. 772-783
    • Pei, J.1    You, X.2    Inflammation, F.Q.3
  • 29
    • 76849106478 scopus 로고    scopus 로고
    • Curcumin improves outcomes and attenuates focal cerebral ischemic injury via antiapoptotic mechanisms in rats
    • 19774461
    • Zhao J, Yu S, Zheng W, Feng G, Luo G, Wang L, et al. Curcumin improves outcomes and attenuates focal cerebral ischemic injury via antiapoptotic mechanisms in rats. Neurochem Res. 2010;35:374-9. doi: 10.1007/s11064-009-0065-y. PubMed PMID: 19774461.
    • (2010) Neurochem Res , vol.35 , pp. 374-379
    • Zhao, J.1    Yu, S.2    Zheng, W.3    Feng, G.4    Luo, G.5    Wang, L.6
  • 30
    • 84858604500 scopus 로고    scopus 로고
    • Selective COX-2 Inhibitors: A Review of Their Structure-Activity Relationships
    • 24250402, PMC3813081
    • Zarghi A, Arfaei S. Selective COX-2 Inhibitors: A Review of Their Structure-Activity Relationships. Iran J Pharm Res. 2011;10:655-83. PubMed PMID: 24250402; PubMed Central PMCID: PMC3813081.
    • (2011) Iran J Pharm Res , vol.10 , pp. 655-683
    • Zarghi, A.1    Arfaei, S.2
  • 31
    • 84876150371 scopus 로고    scopus 로고
    • Identification of 1,8-cineole, borneol, camphor, and thujone as anti-inflammatory compounds in a Salvia officinalis L. Infusion using human gingival fibroblasts
    • 23488631
    • Ehrnhöfer-Ressler MM, Fricke K, Pignitter M, Walker JM, Walker J, Rychlik M, et al. Identification of 1,8-cineole, borneol, camphor, and thujone as anti-inflammatory compounds in a Salvia officinalis L. infusion using human gingival fibroblasts. J Agric Food Chem. 2013;61:3451-9. doi: 10.1021/jf305472t.PubMed PMID: 23488631.
    • (2013) J Agric Food Chem , vol.61 , pp. 3451-3459
    • Ehrnhöfer-Ressler, M.M.1    Fricke, K.2    Pignitter, M.3    Walker, J.M.4    Walker, J.5    Rychlik, M.6
  • 32
    • 0036264003 scopus 로고    scopus 로고
    • Beta-eudesmol induces neurite outgrowth in rat pheochromocytoma cells accompanied by an activation of mitogen-activated protein kinase
    • 12023507
    • Obara Y, Aoki T, Kusano M, Ohizumi Y. Beta-eudesmol induces neurite outgrowth in rat pheochromocytoma cells accompanied by an activation of mitogen-activated protein kinase. J Pharmacol Exp Ther. 2002;301:803-11. doi: 10.1124/jpet.301.3.803. PubMed PMID: 12023507.
    • (2002) J Pharmacol Exp Ther , vol.301 , pp. 803-811
    • Obara, Y.1    Aoki, T.2    Kusano, M.3    Ohizumi, Y.4
  • 34
    • 84938744480 scopus 로고    scopus 로고
    • Pharmacological and neuroprotective profile of an essential oil derived from leaves of Aloysia citrodora Palau
    • 25877296
    • Abuhamdah S, Abuhamdah R, Howes MJ, Al-Olimat S, Ennaceur A, Chazot PL. Pharmacological and neuroprotective profile of an essential oil derived from leaves of Aloysia citrodora Palau. J Pharm Pharmacol. 2015;67:1306-15. doi: 10.1111/jphp.12424. PubMed PMID: 25877296.
    • (2015) J Pharm Pharmacol , vol.67 , pp. 1306-1315
    • Abuhamdah, S.1    Abuhamdah, R.2    Howes, M.J.3    Al-Olimat, S.4    Ennaceur, A.5    Chazot, P.L.6


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