The CREBBP acetyltransferase is a haploinsufficient tumor suppressor in B-cell lymphoma

Cancer Discovery

Volumn 7, Issue 3, 2017, Pages 323-337

  Zhang, Jiyuan ^a   Vlasevska, Sofija ^a   Wells, Victoria A ^a   Nataraj, Sarah ^a   Holmes, Antony B ^a   Duval, Romain ^a   Meyer, Stefanie N ^a   Mo, Tongwei ^a   Basso, Katia ^a,b   Brindle, Paul K ^c   Hussein, Shafinaz ^d   Dalla Favera, Riccardo ^a,b   Pasqualucci, Laura ^a,b  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b NewYork Presbyterian Hospital   (United States)

^c ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^d STATEN ISLAND UNIVERSITY HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; B LYMPHOCYTE RECEPTOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2B; IMMUNOGLOBULIN G3; IMMUNOGLOBULIN M; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 3; TUMOR SUPPRESSOR PROTEIN; BCL6 PROTEIN, HUMAN; CREBBP PROTEIN, HUMAN; CREBBP PROTEIN, MOUSE; PROTEIN BCL 6;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTATION; ARTICLE; B CELL LYMPHOMA; CANCER INCIDENCE; CANCER INHIBITION; CANCER SURVIVAL; CELL DIFFERENTIATION; CELL FATE; CELL PROLIFERATION ASSAY; CELL VIABILITY ASSAY; CHROMATIN IMMUNOPRECIPITATION; CREBBP ACETYLTRANSFERASE GENE; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENE; GENE EXPRESSION; GENE MUTATION; GERMINAL CENTER; HAPLOINSUFFICIENCY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOFLUORESCENCE TEST; IMMUNOGLOBULIN GENE; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SOUTHERN BLOTTING; TUMOR SUPPRESSOR GENE; ANIMAL; B LYMPHOCYTE; C57BL MOUSE; CHROMATIN; DIFFUSE LARGE B CELL LYMPHOMA; DRUG EFFECTS; ENHANCER REGION; FOLLICULAR LYMPHOMA; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PLASMA CELL;

ANIMALS; B-LYMPHOCYTES; CELL DIFFERENTIATION; CHROMATIN; CREB-BINDING PROTEIN; ENHANCER ELEMENTS, GENETIC; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, TUMOR SUPPRESSOR; GERMINAL CENTER; HAPLOINSUFFICIENCY; HUMANS; LYMPHOMA, FOLLICULAR; LYMPHOMA, LARGE B-CELL, DIFFUSE; MICE, INBRED C57BL; MICE, KNOCKOUT; PLASMA CELLS; PROTO-ONCOGENE PROTEINS C-BCL-6;

EID: 85014758342     PISSN: 21598274     EISSN: 21598290     Source Type: Journal    
DOI: 10.1158/2159-8290.CD-16-1417     Document Type: Article

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