Multifunctional Theranostics for Dual-Modal Photodynamic Synergistic Therapy via Stepwise Water Splitting

ACS Applied Materials and Interfaces

Volumn 9, Issue 8, 2017, Pages 6829-6838

  Yang, Dan ^a   Yang, Guixin ^a   Gai, Shili ^a   He, Fei ^a   Li, Chunxia ^b   Yang, Piaoping ^a  

^a HARBIN ENGINEERING UNIVERSITY   (China)

^b ZHEJIANG NORMAL UNIVERSITY   (China)

Author keywords

carbon dots; g C3N4; MOFs; synergistic therapy; up conversion

Indexed keywords

CRYSTALLINE MATERIALS; HYBRID SYSTEMS; INFRARED DEVICES; LIGHT; ORGANOMETALLICS; PHOTODYNAMIC THERAPY;

CARBON DOTS; G-C3N4; MOFS; SYNERGISTIC THERAPY; UP CONVERSION;

PHOTOSENSITIZERS;

NANOPARTICLE; PHOTOSENSITIZING AGENT; WATER;

CHEMISTRY; PHOTOCHEMOTHERAPY; THERANOSTIC NANOMEDICINE;

NANOPARTICLES; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; THERANOSTIC NANOMEDICINE; WATER;

EID: 85014250521     PISSN: 19448244     EISSN: 19448252     Source Type: Journal    
DOI: 10.1021/acsami.6b15203     Document Type: Article

References (70)

1. Idris, N. M.; Gnanasammandhan, M. K.; Zhang, J.; Ho, P. C.; Mahendran, R.; Zhang, Y. In Vivo Photodynamic Therapy Using Upconversion Nanoparticles as Remote-Controlled Nanotransducers Nat. Med. 2012, 18, 1580-U190 10.1038/nm.2933
2. Wang, F.; Chen, X. L.; Zhao, Z. X.; Tang, S. H.; Huang, X. Q.; Lin, C. H.; Cai, C. B.; Zheng, N. F. Synthesis of Magnetic, Fluorescent And Mesoporous Core-Shell-Structured Nanoparticles for Imaging, Targeting and Photodynamic Therapy J. Mater. Chem. 2011, 21, 11244-11252 10.1039/c1jm10329f
3. 2 and Glucose in Blood ACS Appl. Mater. Interfaces 2015, 7, 10548-10555 10.1021/acsami.5b02188
4. Gai, S.; Li, C.; Yang, P.; Lin, J. Recent Progress in Rare Earth Micro/Nanocrystals: Soft Chemical Synthesis, Luminescent Properties, and Biomedical Applications Chem. Rev. 2014, 114, 2343-2389 10.1021/cr4001594
5. Hu, Y.; Yang, Y. M.; Wang, H. J.; Du, H. Synergistic Integration of Layer-by-Layer Assembly of Photosensitizer and Gold Nanorings for Enhanced Photodynamic Therapy in the Near Infrared ACS Nano 2015, 9, 8744-8754 10.1021/acsnano.5b03063
6. Chen, R.; Zhang, J. F.; Wang, Y.; Chen, X. F.; Zapien, J. A.; Lee, C. S. Graphitic Carbon Nitride Nanosheet@Metal-Organic Framework Core-Shell Nanoparticles for Photo-Chemo Combination Therapy Nanoscale 2015, 7, 17299-17305 10.1039/C5NR04436G
7. Huang, P.; Lin, J.; Wang, X. S.; Wang, Z.; Zhang, C. L.; He, M.; Wang, K.; Chen, F.; Li, Z. M.; Shen, G. X.; Cui, D. X.; Chen, X. Y. Light-Triggered Theranostics Based on Photosensitizer-Conjugated Carbon Dots for Simultaneous Enhanced-Fluorescence Imaging and Photodynamic Therapy Adv. Mater. 2012, 24, 5104-5110 10.1002/adma.201200650
8. Idris, N. M.; Lucky, S. S.; Li, Z. Q.; Huang, K.; Zhang, Y. Photoactivation of Core-Shell Titania Coated Upconversion Nanoparticles and Their Effect on Cell Death J. Mater. Chem. B 2014, 2, 7017-7026 10.1039/C4TB01169D
9. Lu, S.; Tu, D. T.; Hu, P.; Xu, J.; Li, R. F.; Wang, M.; Chen, Z.; Huang, M. D.; Chen, X. Y. Multifunctional Nano-Bioprobes Based on Rattle-Structured Upconverting Luminescent Nanoparticles Angew. Chem., Int. Ed. 2015, 54, 7915-7919 10.1002/anie.201501468
10. Pan, L. M.; Liu, J. A.; Shi, J. L. Intranuclear Photosensitizer Delivery and Photosensitization for Enhanced Photodynamic Therapy with Ultralow Irradiance Adv. Funct. Mater. 2014, 24, 7318-7327 10.1002/adfm.201402255
11. Liu, X. M.; Que, I.; Kong, X. G.; Zhang, Y. L.; Tu, L. P.; Chang, Y. L.; Wang, T. T.; Chan, A.; Lowik, C.; Zhang, H. In Vivo 808 nm Image-Guided Photodynamic Therapy Based on an Upconversion Theranostic Nanoplatform Nanoscale 2015, 7, 14914-14923 10.1039/C5NR03690A
12. 2 Photosensitizing Nanoplatform: Near-Infrared Light Mediated in Vivo Photodynamic Therapy via Mitochondria-Involved Apoptosis Pathway ACS Nano 2015, 9, 2584-2599 10.1021/nn506107c
13. Turan, I. S.; Yildiz, D.; Turksoy, A.; Gunaydin, G.; Akkaya, E. U. A Bifunctional Photosensitizer for Enhanced Fractional Photodynamic Therapy: Singlet Oxygen Generation in the Presence and Absence of Light Angew. Chem., Int. Ed. 2016, 55, 2875-2878 10.1002/anie.201511345
14. Yue, X. L.; Yanez, C. O.; Yao, S.; Belfield, K. D. Selective Cell Death by Photochemically Induced pH Imbalance in Cancer Cells J. Am. Chem. Soc. 2013, 135, 2112-2115 10.1021/ja3122312
15. Jin, C. S.; Lovell, J. F.; Chen, J.; Zheng, G. Ablation of Hypoxic Tumors with Dose-Equivalent Photothermal, but Not Photodynamic, Therapy Using a Nanostructured Porphyrin Assembly ACS Nano 2013, 7, 2541-2550 10.1021/nn3058642
16. Heinrich, T. A.; Tedesco, A. C.; Fukuto, J. M.; da Silva, R. S. Production of Reactive Oxygen and Nitrogen Species by Light Irradiation of a Nitrosyl Phthalocyanine Ruthenium Complex as a Strategy for Cancer Treatment Dalton Trans. 2014, 43, 4021-4025 10.1039/c3dt52217b
17. Erler, J. T.; Bennewith, K. L.; Nicolau, M.; Dornhofer, N.; Kong, C.; Le, Q. T.; Chi, J. T. A.; Jeffrey, S. S.; Giaccia, A. J. Lysyl Oxidase is Essential for Hypoxia-Induced Metastasis Nature 2006, 440, 1222-1226 10.1038/nature04695
18. 2 Nanoparticles to Enhance Photodynamic Therapy Adv. Funct. Mater. 2016, 26, 5490-5498 10.1002/adfm.201600676
19. Liu, Y. Y.; Liu, Y.; Bu, W. B.; Cheng, C.; Zuo, C. J.; Xiao, Q. F.; Sun, Y.; Ni, D. L.; Zhang, C.; Liu, J. A.; Shi, J. L. Hypoxia Induced by Upconversion-Based Photodynamic Therapy: Towards Highly Effective Synergistic Bioreductive Therapy in Tumors Angew. Chem., Int. Ed. 2015, 54, 8105-8109 10.1002/anie.201500478
20. Hu, D. H.; Sheng, Z. H.; Gao, G. H.; Siu, F. M.; Liu, C. B.; Wan, Q.; Gong, P.; Zheng, H. R.; Ma, Y. F.; Cai, L. T. Activatable Albumin-Photosensitizer Nanoassemblies for Triple-Modal Imaging and Thermal-Modulated Photodynamic Therapy of Cancer Biomaterials 2016, 93, 10-19 10.1016/j.biomaterials.2016.03.037
21. Chen, Y.; Tan, C.; Zhang, H.; Wang, L. Two-Dimensional Graphene Analogues for Biomedical Applications Chem. Soc. Rev. 2015, 44, 2681-2701 10.1039/C4CS00300D
22. Brown, S. B.; Brown, E. A.; Walker, I. The Present and Future Role of Photodynamic Therapy in Cancer Treatment Lancet Oncol. 2004, 5, 497-508 10.1016/S1470-2045(04)01529-3
23. Li, Y. Y.; Wen, T.; Zhao, R. F.; Liu, X. X.; Ji, T. J.; Wang, H.; Shi, X. W.; Shi, J.; Wei, J. Y.; Zhao, Y. L.; Wu, X. C.; Nie, G. J. Localized Electric Field of Plasmonic Nanoplatform Enhanced Photodynamic Tumor Therapy ACS Nano 2014, 8, 11529-11542 10.1021/nn5047647
24. Zhang, C.; Zhao, K. L.; Bu, W. B.; Ni, D. L.; Liu, Y. Y.; Feng, J. W.; Shi, J. L. Marriage of Scintillator and Semiconductor for Synchronous Radiotherapy and Deep Photodynamic Therapy with Diminished Oxygen Dependence Angew. Chem., Int. Ed. 2015, 54, 1770-1774 10.1002/anie.201408472
25. Kachynski, A. V.; Pliss, A.; Kuzmin, A. N.; Ohulchanskyy, T. Y.; Baev, A.; Qu, J.; Prasad, P. N. Photodynamic Therapy by in Situ Nonlinear Photon Conversion Nat. Photonics 2014, 8, 455-461 10.1038/nphoton.2014.90
26. Liu, J.; Liu, Y.; Liu, N. Y.; Han, Y. Z.; Zhang, X.; Huang, H.; Lifshitz, Y.; Lee, S. T.; Zhong, J.; Kang, Z. H. Metal-Free Efficient Photocatalyst for Stable Visible Water Splitting via a Two-Electron Pathway Science 2015, 347, 970-974 10.1126/science.aaa3145
27. Martin, D. J.; Reardon, P. J. T.; Moniz, S. J. A.; Tang, J. W. Visible Light-Driven Pure Water Splitting by a Nature-Inspired Organic Semiconductor-Based System J. Am. Chem. Soc. 2014, 136, 12568-12571 10.1021/ja506386e
28. Chen, C. K.; Chen, H. M.; Chen, C. J.; Liu, R. S. Plasmon-Enhanced Near-Infrared-Active Materials In Photoelectrochemical Water Splitting Chem. Commun. 2013, 49, 7917-7919 10.1039/c3cc42567c
29. 3 Single Crystals Science 2015, 347, 967-970 10.1126/science.aaa5760
30. Cao, S. W.; Low, J. X.; Yu, J. G.; Jaroniec, M. Polymeric Photocatalysts Based on Graphitic Carbon Nitride Adv. Mater. 2015, 27, 2150-2176 10.1002/adma.201500033
31. Highfield, J. Advances and Recent Trends in Heterogeneous Photo(Electro)-Catalysis for Solar Fuels and Chemicals Molecules 2015, 20, 6739-6793 10.3390/molecules20046739
32. 4 Based Low Cost Photocatalytic System: Activity Enhancement and Emerging Applications Catal. Sci. Technol. 2015, 5, 5048-5061 10.1039/C5CY00938C
33. 4 Material J. Mater. Chem. A 2014, 2, 17521-17529 10.1039/C4TA02781G
34. 4 Nanosheets as Efficient Photosensitizers and pH-Responsive Drug Nanocarriers for Cancer Imaging And Therapy J. Mater. Chem. B 2014, 2, 1031-1037 10.1039/c3tb21479f
35. Liu, J. H.; Zhang, Y. W.; Lu, L. H.; Wu, G.; Chen, W. Self-Regenerated Solar-Driven Photocatalytic Water-Splitting by Urea Derived Graphitic Carbon Nitride With Platinum Nanoparticles Chem. Commun. 2012, 48, 8826-8828 10.1039/c2cc33644h
36. Chan, C. F.; Zhou, Y.; Guo, H. Y.; Zhang, J. Y.; Jiang, L. J.; Chen, W.; Shiu, K. K.; Wong, W. K.; Wong, K. L. pH-Dependent Cancer-Directed Photodynamic Therapy by a Water-Soluble Graphitic-Phase Carbon Nitride-Porphyrin Nanoprobe ChemPlusChem 2016, 81, 535-540 10.1002/cplu.201600085
37. Wan, H.; Zhang, Y.; Zhang, W. B.; Zou, H. F. Robust Two-Photon Visualized Nanocarrier with Dual Targeting Ability for Controlled Chemo-Photodynamic Synergistic Treatment of Cancer ACS Appl. Mater. Interfaces 2015, 7, 9608-9618 10.1021/acsami.5b01165
38. Li, H. T.; Kang, Z. H.; Liu, Y.; Lee, S. T. Carbon Nanodots: Synthesis, Properties and Applications J. Mater. Chem. 2012, 22, 24230-24253 10.1039/c2jm34690g
39. Ming, H.; Ma, Z.; Liu, Y.; Pan, K. M.; Yu, H.; Wang, F.; Kang, Z. H. Large Scale Electrochemical Synthesis of High Quality Carbon Nanodots and Their Photocatalytic Property Dalton Trans. 2012, 41, 9526-9531 10.1039/c2dt30985h
40. He, L.; Wang, T. T.; An, J. P.; Li, X. M.; Zhang, L. Y.; Li, L.; Li, G. Z.; Wu, X. T.; Su, Z. M.; Wang, C. G. Carbon Nanodots@Zeolitic Imidazolate Framework-8 Nanoparticles for Simultaneous Ph-Responsive Drug Delivery and Fluorescence Imaging CrystEngComm 2014, 16, 3259-3263 10.1039/c3ce42506a
41. 4:Yb,Tm: Enhanced Visible-Near Infrared Photocatalytic Activity Chem. Commun. 2016, 52, 453-456 10.1039/C5CC07372C
42. Xu, X. Y.; Ray, R.; Gu, Y. L.; Ploehn, H. J.; Gearheart, L.; Raker, K.; Scrivens, W. A. Electrophoretic Analysis and Purification of Fluorescent Single-Walled Carbon Nanotube Fragments J. Am. Chem. Soc. 2004, 126, 12736-12737 10.1021/ja040082h
43. Ge, J. C.; Jia, Q. Y.; Liu, W. M.; Lan, M. H.; Zhou, B. J.; Guo, L.; Zhou, H. Y.; Zhang, H. Y.; Wang, Y.; Gu, Y.; Meng, X. M.; Wang, P. F. Carbon Dots with Intrinsic Theranostic Properties for Bioimaging, Red-Light-Triggered Photodynamic/Photothermal Simultaneous Therapy In Vitro and In Vivo Adv. Healthcare Mater. 2016, 5, 665-675 10.1002/adhm.201500720
44. Feng, T.; Ai, X. Z.; Ong, H. M.; Zhao, Y. L. Dual-Responsive Carbon Dots for Tumor Extracellular Microenvironment Triggered Targeting and Enhanced Anticancer Drug Delivery ACS Appl. Mater. Interfaces 2016, 8, 18732-18740 10.1021/acsami.6b06695
45. Jia, X.; Pei, M. L.; Zhao, X. B.; Tian, K.; Zhou, T. T.; Liu, P. PEGylated Oxidized Alginate-DOX Prodrug Conjugate Nanoparticles Cross-Linked with Fluorescent Carbon Dots for Tumor Theranostics ACS Biomater. Sci. Eng. 2016, 2, 1641-1648 10.1021/acsbiomaterials.6b00443
46. Ge, J.; Lan, M.; Zhou, B.; Liu, W.; Guo, L.; Wang, H.; Jia, Q.; Niu, G.; Huang, X.; Zhou, H.; Meng, X.; Wang, P.; Lee, C.-S.; Zhang, W.; Han, X. A graphene Quantum Dot Photodynamic Therapy Agent with High Singlet Oxygen Generation Nat. Commun. 2014, 5, 4596-4605 10.1038/ncomms5596
47. Ge, J.; Jia, Q.; Liu, W.; Guo, L.; Liu, Q.; Lan, M.; Zhang, H.; Meng, X.; Wang, P. Red-Emissive Carbon Dots for Fluorescent, Photoacoustic, and Thermal Theranostics in Living Mice Adv. Mater. 2015, 27, 4169-4177 10.1002/adma.201500323
48. van Veggel, F. Near-Infrared Quantum Dots and Their Delicate Synthesis, Challenging Characterization, and Exciting Potential Applications Chem. Mater. 2014, 26, 111-122 10.1021/cm4021436
49. Li, H. T.; Liu, R. H.; Lian, S. Y.; Liu, Y.; Huang, H.; Kang, Z. H. Near-Infrared Light Controlled Photocatalytic Activity of Carbon Quantum Dots for Highly Selective Oxidation Reaction Nanoscale 2013, 5, 3289-3297 10.1039/c3nr00092c
50. Liu, R. H.; Huang, H.; Li, H. T.; Liu, Y.; Zhong, J.; Li, Y. Y.; Zhang, S.; Kang, Z. H. Metal Nanoparticle/Carbon Quantum Dot Composite as a Photocatalyst for High-Efficiency Cyclohexane Oxidation ACS Catal. 2014, 4, 328-336 10.1021/cs400913h
51. 4 Core-Shell-Shell Nanoparticles through Gadolinium Sublattice-Mediated Energy Migration Dyes Pigm. 2016, 130, 99-105 10.1016/j.dyepig.2016.03.015
52. Dai, Y. L.; Xiao, H. H.; Liu, J. H.; Yuan, Q. H.; Ma, P. A.; Yang, D. M.; Li, C. X.; Cheng, Z. Y.; Hou, Z. Y.; Yang, P. P.; Lin, J. In Vivo Multimodality Imaging and Cancer Therapy by Near-Infrared Light-Triggered trans-Platinum Pro-Drug-Conjugated Upconverison Nanoparticles J. Am. Chem. Soc. 2013, 135, 18920-18929 10.1021/ja410028q
53. He, F.; Yang, G. X.; Yang, P. P.; Yu, Y. X.; Lv, R. C.; Li, C. X.; Dai, Y. L.; Gai, S. L.; Lin, J. A New Single 808 nm NIR Light-Induced Imaging-Guided Multifunctional Cancer Therapy Platform Adv. Funct. Mater. 2015, 25, 3966-3976 10.1002/adfm.201500464
54. Ai, X. Z.; Ho, C. J. H.; Aw, J.; Attia, A. B. E.; Mu, J.; Wang, Y.; Wang, X. Y.; Wang, Y.; Liu, X. G.; Chen, H. B.; Gao, M. Y.; Chen, X. Y.; Yeow, E. K. L.; Liu, G.; Olivo, M.; Xing, B. G. In Vivo Covalent Cross-Linking of Photon-Converted Rare-Earth Nanostructures for Tumour Localization and Theranostics Nat. Commun. 2016, 7, 10432-10442 10.1038/ncomms10432
55. Wang, C.; Cheng, L.; Liu, Z. Upconversion Nanoparticles for Photodynamic Therapy and other Cancer Therapeutics Theranostics 2013, 3, 317-330 10.7150/thno.5284
56. Wang, C.; Tao, H. Q.; Cheng, L.; Liu, Z. Near-Infrared Light Induced in Vivo Photodynamic Therapy of Cancer Based on Upconversion Nanoparticles Biomaterials 2011, 32, 6145-6154 10.1016/j.biomaterials.2011.05.007
57. Wang, F.; Banerjee, D.; Liu, Y. S.; Chen, X. Y.; Liu, X. G. Upconversion Nanoparticles in Biological Labeling, Imaging, and Therapy Analyst 2010, 135, 1839-1854 10.1039/c0an00144a
58. Guan, M.; Dong, H.; Ge, J.; Chen, D.; Sun, L.; Li, S.; Wang, C.; Yan, C.; Wang, P.; Shu, C. Multifunctional Upconversion-Nanoparticles-Trismethylpyridylporphyrin- Fullerene Nanocomposite: a Near-Infrared Light-Triggered Theranostic Platform for Imaging-Guided Photodynamic Therapy NPG Asia Mater. 2015, 7, e205 10.1038/am.2015.82
59. 3+-Based Upconversion Nanomaterials for Drug Delivery Chem. Soc. Rev. 2015, 44, 1416-1448 10.1039/C4CS00155A
60. Zhang, Z.; Chen, Y.; Xu, X.; Zhang, J.; Xiang, G.; He, W.; Wang, X. Well-Defined Metal-Organic Framework Hollow Nanocages Angew. Chem., Int. Ed. 2014, 53, 429-433 10.1002/anie.201308589
61. Lu, K. D.; He, C. B.; Lin, W. B. A Chlorin-Based Nanoscale Metal-Organic Framework for Photodynamic Therapy of Colon Cancers J. Am. Chem. Soc. 2015, 137, 7600-7603 10.1021/jacs.5b04069
62. Guo, H. L.; Zhu, Y. Z.; Wang, S.; Su, S. Q.; Zhou, L.; Zhang, H. J. Combining Coordination Modulation with Acid-Base Adjustment for the Control over Size of Metal-Organic Frameworks Chem. Mater. 2012, 24, 444-450 10.1021/cm202593h
63. Corma, A.; Garcia, H.; Llabres i Xamena, F. X. L. I. Engineering Metal Organic Frameworks for Heterogeneous Catalysis Chem. Rev. 2010, 110, 4606-4655 10.1021/cr9003924
64. Zheng, X. P.; Shi, J. X.; Bu, Y.; Tian, G.; Zhang, X.; Yin, W. Y.; Gao, B. F.; Yang, Z. Y.; Hu, Z. B.; Liu, X. F.; Yan, L.; Gu, Z. J.; Zhao, Y. L. Silica-Coated Bismuth Sulfide Nanorods as Multimodal Contrast Agents for a Non-Invasive Visualization of the Gastrointestinal Tract Nanoscale 2015, 7, 12581-12591 10.1039/C5NR03068D
65. 3+ Complex Nanoparticles Chem.-Eur. J. 2011, 17, 7007-7012 10.1002/chem.201003712
66. xS Double-Shelled Hollow Spheres for Enhanced Chemo-/Photothermal Anti-Cancer Therapy and Dual-Modal Imaging Nanoscale 2015, 7, 12180-12191 10.1039/C5NR02269J
67. Xiong, L. Q.; Yang, T. S.; Yang, Y.; Xu, C. J.; Li, F. Y. Long-Term in Vivo Biodistribution Imaging and Toxicity of Polyacrylic Acid-Coated Upconversion Nanophosphors Biomaterials 2010, 31, 7078-7085 10.1016/j.biomaterials.2010.05.065
68. Haase, M.; Schafer, H. Upconverting Nanoparticles Angew. Chem., Int. Ed. 2011, 50, 5808-5829 10.1002/anie.201005159
69. Wang, S. D.; Zhu, Z. F.; Chang, Y. J.; Wang, H.; Yuan, N.; Li, G. P.; Yu, D. B.; Jiang, Y. Ammonium Hydroxide Modulated Synthesis of High-Quality Fluorescent Carbon Dots for White Leds with Excellent Color Rendering Properties Nanotechnology 2016, 27, 295202-295211 10.1088/0957-4484/27/29/295202
70. Wang, F.; Han, Y.; Lim, C. S.; Lu, Y. H.; Wang, J.; Xu, J.; Chen, H. Y.; Zhang, C.; Hong, M. H.; Liu, X. G. Simultaneous Phase and Size Control of Upconversion Nanocrystals through Lanthanide Doping Nature 2010, 463, 1061-1065 10.1038/nature08777