Mechanism of ICU-acquired weakness: muscle contractility in critical illness

Intensive Care Medicine

Volumn 43, Issue 4, 2017, Pages 584-586

  Batt, Jane ^a   Mathur, Sunita ^b   Katzberg, Hans D ^c  

^a ST MICHAEL'S HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CRITICAL ILLNESS; EDITORIAL; HUMAN; INTENSIVE CARE UNIT; INTENSIVE CARE UNIT ACQUIRED WEAKNESS; MUSCLE ATROPHY; MUSCLE CONTRACTILITY; MUSCLE EXCITATION; MUSCLE FIBER MEMBRANE; MUSCLE MASS; MUSCLE WEAKNESS; NONHUMAN; POLYNEUROPATHY; ANIMAL; BREATHING MUSCLE; MUSCLE CONTRACTION; PATHOPHYSIOLOGY;

ANIMALS; CRITICAL ILLNESS; HUMANS; INTENSIVE CARE UNITS; MUSCLE CONTRACTION; MUSCLE WEAKNESS; RESPIRATORY MUSCLES;

EID: 85014081388     PISSN: 03424642     EISSN: 14321238     Source Type: Journal    
DOI: 10.1007/s00134-017-4730-3     Document Type: Editorial

References (20)

1. Herridge MS, Chu LM, Matte A et al (2016) The RECOVER Program: disability risk groups and one year outcome after 7 days of mechanical ventilation. Am J Respir Crit Care Med 194:831–844. doi:10.1164/rccm.201512-2343OC
2. Manini TM, Clark BC (2012) Dynapenia and aging: an update. J Gerontol A Biol Sci Med Sci 67:28–40. doi:10.1093/gerona/glr010
3. Larsson L, Li X, Berg HE, Frontera WR (1996) Effects of removal of weight-bearing function on contractility and myosin isoform composition in single human skeletal muscle cells. Pflugers Arch Eur J Physiol 432:320–328
4. Dos SC, Hussain SN, Mathur S et al (2016) Mechanisms of chronic muscle wasting and dysfunction after an intensive care unit stay. A pilot study. Am J Respir Crit Care Med 194:821–830. doi:10.1164/rccm.201512-2344OC
5. Trojaborg W (2006) Electrophysiologic techniques in critical illness-associated weakness. J Neurol Sci 242:83–85. doi:10.1016/j.jns.2005.11.019
6. Rich MM, Pinter MJ (2003) Crucial role of sodium channel fast inactivation in muscle fibre inexcitability in a rat model of critical illness myopathy. J Physiol 547:555–566. doi:10.1113/jphysiol.2002.035188
7. Kraner SD, Wang Q, Novak KR, Cheng D, Cool DR, Peng J, Rich MM (2011) Upregulation of the CaV 1.1-ryanodine receptor complex in a rat model of critical illness myopathy. Am J Physiol Regul Integr Comp Physiol 300:R1384–R1391. doi:10.1152/ajpregu.00032.2011
8. 2+ channel function in an acute septic myopathy model. J Neurol 257:546–555. doi:10.1007/s00415-009-5362-5
9. Friedrich O, Reid MB, Van den Berghe G, Vanhorebeek I, Hermans G, Rich MM, Larsson L (2015) The sick and the weak: neuropathies/myopathies in the critically ill. Physiol Rev 95:1025–1109. doi:10.1152/physrev.00028.2014
10. 2+ release contributes to muscle weakness in a rat model of critical illness myopathy. Crit Care 20:254. doi:10.1186/1471-2164-12-602
11. Callahan LA, Nethery D, Stofan D, Dimarco A, Supinski G (2001) Free radical-induced contractile protein dysfunction in endotoxin-induced sepsis. Am J Respir Cell Mol Biol 24:210–217. doi:10.1165/ajrcmb.24.2.4075
12. Latronico N, Bolton CF (2011) Critical illness polyneuropathy and myopathy: a major cause of muscle weakness and paralysis. Lancet Neurol 10:931–941. doi:10.1016/S1474-4422(11)70178-8
13. Corpeno KR, Salah H, Gastaldello S et al (2016) Mechano-signalling pathways in an experimental intensive critical illness myopathy model. J Physiol 594:4371–4388. doi:10.1113/JP271973
14. Rocheteau P, Chatre L, Briand D et al (2015) Sepsis induces long-term metabolic and mitochondrial muscle stem cell dysfunction amenable by mesenchymal stem cell therapy. Nat Commun 6:10145. doi:10.1038/ncomms10145
15. Carre JE, Orban JC, Re L et al (2010) Survival in critical illness is associated with early activation of mitochondrial biogenesis. Am J Respir Crit Care Med 182:745–751. doi:10.1164/rccm.201003-0326OC
16. Hardin BJ, Campbell KS, Smith JD, Arbogast S, Smith J, Moylan JS, Reid MB (2008) TNF-alpha acts via TNFR1 and muscle-derived oxidants to depress myofibrillar force in murine skeletal muscle. J Appl Physiol 104:694–699. doi:10.1152/japplphysiol.00898.2007
17. Li YP, Lecker SH, Chen Y, Waddell ID, Goldberg AL, Reid MB (2003) TNF-alpha increases ubiquitin-conjugating activity in skeletal muscle by up-regulating UbcH2/E220k. FASEB J 17:1048–1057. doi:10.1096/fj.02-0759com
18. Cooney R, Owens E, Jurasinski C, Gray K, Vannice J, Vary T (1994) Interleukin-1 receptor antagonist prevents sepsis-induced inhibition of protein synthesis. Am J Physiol 267:E636–E641
19. Friedrich O, Yi B, Edwards JN et al (2014) IL-1alpha reversibly inhibits skeletal muscle ryanodine receptor. A novel mechanism for critical illness myopathy? Am J Respir Cell Mol Biol 50:1096–1106. doi:10.1165/rcmb.2013-0059OC
20. Romanello V, Guadagnin E, Gomes L et al (2010) Mitochondrial fission and remodelling contributes to muscle atrophy. EMBO J 29:1774–1785. doi:10.3389/fphys.2015.00422