Double Knockout of the Na+-Driven Cl2/HCO3 2 exchanger and Na+/Cl- cotransporter induces hypokalemia and volume depletion

Journal of the American Society of Nephrology

Volumn 28, Issue 1, 2017, Pages 130-139

  Sinning, Anne ^a   Radionov, Nikita ^b,c   Trepiccione, Francesco ^b,c   López Cayuqueo, Karen I ^b,c,d   Jayat, Maximilien ^b,c   Baron, Stéphanie ^e   Cornière, Nicolas ^f   Alexander, R Todd ^g   Hadchouel, Juliette ^b,c   Eladari, Dominique ^b,c,e   Hübner, Christian A ^a   Chambrey, Régine ^b,c,h  

^a JENA UNIVERSITY HOSPITAL   (Germany)

^b PARIS CARDIOVASCULAR RESEARCH CENTER   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d CENTRO DE ESTUDIOS CIENTÍFICOS CECS   (Chile)

^e HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

^f Service de Néphrologie et Transplantation Rénale   (France)

^g UNIVERSITY OF ALBERTA   (Canada)

^h CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALDOSTERONE; BICARBONATE CHLORIDE ANTIPORTER; CALCIUM ACTIVATED POTASSIUM CHANNEL; EPITHELIAL SODIUM CHANNEL; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; PENDRIN; POTASSIUM ION; SODIUM CHLORIDE COTRANSPORTER; SODIUM ION; SODIUM POTASSIUM CHLORIDE COTRANSPORTER 2; SODIUM PROTON EXCHANGE PROTEIN 3; THIAZIDE DIURETIC AGENT; AMILORIDE; RENIN; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HOMEOSTASIS; HYPOKALEMIA; HYPOVOLEMIA; MOUSE; NONHUMAN; PLASMA RENIN ACTIVITY; POTASSIUM BLOOD LEVEL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SODIUM BALANCE; SODIUM DEPLETION; UPREGULATION; ALDOSTERONE BLOOD LEVEL; ALDOSTERONE URINE LEVEL; GENE DISRUPTION; HEMATOCRIT; IMMUNOBLOTTING; SODIUM EXCRETION; WESTERN BLOTTING; ANIMAL; BLOOD VOLUME; KNOCKOUT MOUSE; PHYSIOLOGY;

ANIMALS; BLOOD VOLUME; CHLORIDE-BICARBONATE ANTIPORTERS; HYPOKALEMIA; MICE; MICE, KNOCKOUT; UP-REGULATION;

EID: 85013766611     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2015070734     Document Type: Article

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