Double knockout of pendrin and Na-Cl cotransporter (NCC) causes severe salt wasting, volume depletion, and renal failure

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 33, 2012, Pages 13368-13373

  Soleimani, Manoocher ^a,b,c   Barone, Sharon ^a,b,c   Xu, Jie ^a,b,c   Shull, Gary E ^b   Siddiqui, Faraz ^b   Zahedi, Kamyar ^a,b,c   Amlal, Hassane ^b,c  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF CINCINNATI   (United States)

Author keywords

Diuretics; Kidney tubules; Nephrogenic diabetes insipidus

Indexed keywords

PENDRIN; SODIUM CHLORIDE COTRANSPORTER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DISEASE SEVERITY; HYPOKALEMIA; KIDNEY FAILURE; METABOLIC ALKALOSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SALT WASTING;

ALKALOSIS; ANIMALS; ANION TRANSPORT PROTEINS; BODY WEIGHT; DIURESIS; KIDNEY; KIDNEY FUNCTION TESTS; MICE; MICE, KNOCKOUT; MODELS, BIOLOGICAL; POTASSIUM; RECEPTORS, DRUG; RENAL INSUFFICIENCY; SODIUM; SODIUM CHLORIDE; SODIUM CHLORIDE, DIETARY; SYMPORTERS; VASOPRESSINS; WATER-ELECTROLYTE BALANCE;

EID: 84865160669     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1202671109     Document Type: Article

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