Bi-phasic regulation of glycogen content in astrocytes via Cav-1/PTEN/PI3K/AKT/GSK-3β pathway by fluoxetine

Psychopharmacology

Volumn 234, Issue 7, 2017, Pages 1069-1077

  Bai, Qiufang ^a   Song, Dan ^a   Gu, Li ^a   Verkhratsky, Alexei ^b,c   Peng, Liang ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c BASQUE FOUNDATION FOR SCIENCE   (Spain)

Author keywords

Cav 1; Fluoxetine; Glycogen; GSK 3 ; PI3K AKT; PTEN

Indexed keywords

CAVEOLIN 1; FLUOXETINE; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTAMATE AMMONIA LIGASE; GLYCOGEN SYNTHASE KINASE 3BETA; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; SMALL INTERFERING RNA; CAV1 PROTEIN, MOUSE; GLYCOGEN; PIK3CD PROTEIN, MOUSE; PTEN PROTEIN, MOUSE; SEROTONIN UPTAKE INHIBITOR;

ANIMAL CELL; ARTICLE; ASTROCYTE; CELL DIFFERENTIATION; CELL MEMBRANE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; ENZYME INHIBITION; GENE EXPRESSION; GLYCOGEN ANALYSIS; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; DRUG EFFECTS; GENE SILENCING; METABOLISM; PHOSPHORYLATION; PRIMARY CELL CULTURE;

ANIMALS; ASTROCYTES; CAVEOLIN 1; FLUOXETINE; GENE KNOCKDOWN TECHNIQUES; GLYCOGEN; GLYCOGEN SYNTHASE KINASE 3 BETA; MICE; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PRIMARY CELL CULTURE; PTEN PHOSPHOHYDROLASE; RNA, SMALL INTERFERING; SEROTONIN UPTAKE INHIBITORS; SIGNAL TRANSDUCTION;

EID: 85013628596     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-017-4547-3     Document Type: Article

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