Engineering rTCA pathway and C4-dicarboxylate transporter for l-malic acid production

Applied Microbiology and Biotechnology

Volumn 101, Issue 10, 2017, Pages 4041-4052

  Chen, Xiulai ^a   Wang, Yuancai ^a   Dong, Xiaoxiang ^a   Hu, Guipeng ^a   Liu, Liming ^a  

^a JIANGNAN UNIVERSITY   (China)

Author keywords

C4 Dicarboxylate transporter; l Malic acid; Pathway optimization; Reductive TCA pathway; Saccharomyces cerevisiae

Indexed keywords

ASPERGILLUS; BIOCHEMISTRY; BIOSYNTHESIS; CALCIUM CARBONATE; GENE EXPRESSION; METABOLIC ENGINEERING; YEAST;

BIOSYNTHESIS PATHWAYS; C4-DICARBOXYLATE TRANSPORTER; GENE EXPRESSION LEVELS; L-MALIC ACID; OPTIMIZATION STRATEGY; PYRUVATE CARBOXYLASE; REDUCTIVE TCA PATHWAY; SCHIZOSACCHAROMYCES POMBE;

CARBOXYLATION;

2 OXOGLUTARIC ACID; ARGININE; C 4 DICARBOXYLATE TRANSPORTER; CALCIUM CARBONATE; CITRIC ACID; COMPLEMENTARY DNA; DICARBOXYLATE TRANSPORTER; FUMARIC ACID; FUNGAL DNA; GLYCEROL; LYSINE; MALATE DEHYDROGENASE; MALIC ACID; PYRUVATE CARBOXYLASE; PYRUVATE DECARBOXYLASE; PYRUVIC ACID; RESTRICTION ENDONUCLEASE; SUCCINIC ACID; TRICARBOXYLIC ACID; UNCLASSIFIED DRUG; MALIC ACID DERIVATIVE;

BIOENGINEERING; BIOLOGICAL PRODUCTION; ENZYME ACTIVITY; FUNGUS; GENE EXPRESSION; METABOLISM; OPTIMIZATION; ORGANIC ACID; REDUCTION;

ARTICLE; ASPERGILLUS FLAVUS; BIOSYNTHESIS; ENZYME ACTIVITY; FLUORESCENCE MICROSCOPY; GENE EXPRESSION; METABOLIC ENGINEERING; NONHUMAN; RHIZOPUS ORYZAE; UBIQUITINATION; CITRIC ACID CYCLE; ENZYMOLOGY; GENETICS; METABOLISM; PH; PHYSIOLOGY; PROCEDURES; RHIZOPUS; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES;

ASPERGILLUS FLAVUS; RHIZOPUS ORYZAE; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES POMBE;

ASPERGILLUS FLAVUS; BIOSYNTHETIC PATHWAYS; CITRIC ACID CYCLE; DICARBOXYLIC ACID TRANSPORTERS; GENE EXPRESSION; HYDROGEN-ION CONCENTRATION; MALATE DEHYDROGENASE; MALATES; METABOLIC ENGINEERING; PYRUVATE CARBOXYLASE; PYRUVIC ACID; RHIZOPUS; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES; UBIQUITINATION;

EID: 85013371899     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-017-8141-8     Document Type: Article

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