Low long non-coding RNA HOTAIR expression is associated with down-regulation of Nrf2 in the spermatozoa of patients with asthenozoospermia or oligoasthenozoospermia

International Journal of Clinical and Experimental Pathology

Volumn 8, Issue 11, 2015, Pages 14198-14205

  Zhang, Lixin ^a   Liu, Zhineng ^a   Li, Xiaokang ^a   Zhang, Ping ^a   Wang, Jia ^a   Zhu, Dandan ^a   Chen, Xinping ^a   Ye, Lihua ^a  

^a NANTONG UNIVERSITY   (China)

Author keywords

Asthenozoospermia and oligoasthenozoospermia; Histone acetylation; HOTAIR; Nrf2; ROS

Indexed keywords

HISTONE; HOTAIR LONG UNTRANSLATED RNA, HUMAN; LONG UNTRANSLATED RNA; NFE2L2 PROTEIN, HUMAN; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR NRF2;

ACETYLATION; ADULT; ASTHENOZOOSPERMIA; CASE CONTROL STUDY; CELL LINE; CELL SURVIVAL; DOWN REGULATION; GENETIC TRANSFECTION; GENETICS; HUMAN; MALE; METABOLISM; MIDDLE AGED; OLIGOSPERMIA; PATHOLOGY; PROMOTER REGION; RNA INTERFERENCE; SPERMATOZOON; SPERMATOZOON MOTILITY;

ACETYLATION; ADULT; ASTHENOZOOSPERMIA; CASE-CONTROL STUDIES; CELL LINE; CELL SURVIVAL; DOWN-REGULATION; HISTONES; HUMANS; MALE; MIDDLE AGED; NF-E2-RELATED FACTOR 2; OLIGOSPERMIA; PROMOTER REGIONS, GENETIC; REACTIVE OXYGEN SPECIES; RNA INTERFERENCE; RNA, LONG NONCODING; SPERM MOTILITY; SPERMATOZOA; SUPEROXIDE DISMUTASE; TRANSFECTION;

EID: 85013350139     PISSN: None     EISSN: 19362625     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Boivin J, Bunting L, Collins JA and Nygren KG. International estimates of infertility prevalence and treatment-seeking: potential need and demand for infertility medical care. Hum Reprod 2007; 22: 1506-1512.
2. De Kretser DM. Male infertility. Lancet 1997; 349: 787-790.
3. Curi SM, Ariagno JI, Chenlo PH, Mendeluk GR, Pugliese MN, Sardi Segovia LM, Repetto HE and Blanco AM. Asthenozoospermia: analysis of a large population. Arch Androl 2003; 49: 343-349.
4. Agarwal A, Gupta S and Sharma R. Oxidative stress and its implications in female infertilitya clinician's perspective. Reprod Biomed Online 2005; 11: 641-650.
5. Lamond S, Watkinson M, Rutherford T, Laing K, Whiting A, Smallwood A, Nargund G, Campbell S and Banerjee S. Gene-specific chromatin damage in human spermatozoa can be blocked by antioxidants that target mitochondria. Reprod Biomed Online 2003; 7: 407-418.
6. Macanovic B, Vucetic M, Jankovic A, Stancic A, Buzadzic B, Garalejic E, Korac A, Korac B and Otasevic V. Correlation between sperm parameters and protein expression of antioxidative defense enzymes in seminal plasma: a pilot study. Dis Markers 2015; 2015: 436236.
7. Cheng Q, Kalabus JL, Zhang J and Blanco JG. A conserved antioxidant response element (ARE) in the promoter of human carbonyl reductase 3 (CBR3) mediates induction by the master redox switch Nrf2. Biochem Pharmacol 2012; 83: 139-148.
8. Esakky P, Hansen DA, Drury AM and Moley KH. Modulation of cell cycle progression in the spermatocyte cell line [GC-2spd(ts) Cell-Line] by cigarette smoke condensate (CSC) via arylhydrocarbon receptor-nuclear factor erythroid 2-related factor 2 (Ahr-Nrf2) pathway. Biol Reprod 2014; 90: 9.
9. Nakamura BN, Lawson G, Chan JY, Banuelos J, Cortés MM, Hoang YD, Ortiz L, Rau BA and Luderer U. Knockout of the transcription factor NRF2 disrupts spermatogenesis in an age-dependent manner. Free Radic Biol Med 2010; 49: 1368-1379.
10. Chen K, Mai Z, Zhou Y, Gao X and Yu B. Low NRF2 mRNA expression in spermatozoa from men with low sperm motility. Tohoku J Exp Med 2012; 228: 259-266.
11. Caley DP, Pink RC, Trujillano D and Carter DR. Long noncoding RNAs, chromatin, and development. ScientificWorldJournal 2010; 10: 90-102.
12. Berghoff EG, Clark MF, Chen S, Cajigas I, Leib DE and Kohtz JD. Evf2 (Dlx6as) lncRNA regulates ultraconserved enhancer methylation and the differential transcriptional control of adjacent genes. Development 2013; 140: 4407-16.
13. Klattenhoff CA, Scheuermann JC, Surface LE, Bradley RK, Fields PA, Steinhauser ML, Ding H, Butty VL, Torrey L, Haas S, Abo R, Tabebordbar M, Lee RT, Burge CB and Boyer LA. Braveheart, a long noncoding RNA required for cardiovascular lineage commitment. Cell 2013; 152: 570-583.
14. Luk AC, Chan WY, Rennert OM and Lee TL. Long noncoding RNAs in spermatogenesis: insights from recent high-through puttranscriptome studies. Reproduction 2014; 147: R131-141.
15. Woo CJ and Kingston RE. HOTAIR lifts noncoding RNAs to new levels. Cell 2007; 129: 1257-1259.
16. Ye P, Wang T, Liu WH, Li XC, Tang LJ and Tian FZ. Enhancing HOTAIR/MiR-10b drive liver normal stem cells to arise malignant transformation tendency through inducing epithelial-mesenchymal transitions. Rejuvenation Res 2015; 18: 332-40.
17. World Health Organization. Laboratory manual for the examination of human semen and sperm-cervical mucus interaction. 5th edition. Geneva: World Health Organization; 2010. pp. 10-56.
18. Kim JH, Jee BC, Lee JM, Suh CS and Kim SH. Histone acetylation level and histone acetyltransferase/deacetylase activity in ejaculatedsperm from normozoospermic men. Yonsei Med J 2014; 55: 1333-1340.
19. Liang M, Li W, Tian H, Hu T, Wang L, Lin Y, Li Y, Huang H and Sun F. Sequential expression of long noncoding RNA as mRNA gene expression in specific stages of mouse spermatogenesis. Sci Rep 2014; 4: 5966.
20. Turner BM. Histone acetylation and control of gene expression. J Cell Sci 1999; 99: 13-20.
21. Yap KL, Li S, Muñoz-Cabello AM, Raguz S, Zeng L, Mujtaba S, Gil J, Walsh MJ and Zhou MM. Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a. Mol Cell 2010; 38: 662-674.
22. Dandekar SP, Nadkarni GD, Kulkarni VS and Punekar S. Lipid peroxidation and antioxidant enzymes in male infertility. J Postgrad Med 2002; 48: 186-189.
23. Cocchia N, Pasolini MP, Mancini R, Petrazzuolo O, Cristofaro I, Rosapane I, Sica A, Tortora G, Lorizio R, Paraggio G and Mancini A. Effect of sod (superoxide dismutase) protein supplementation in semen extenders on motility, viability, acrosome status and ERK (extracellular signal-regulated kinase) protein phosphorylation of chilled stallion spermatozoa. Theriogenology 2011; 75: 1201-1210.