TNF-α decreases lipoprotein lipase activity in 3T3-L1 adipocytes by up-regulation of angiopoietin-like protein 4

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1862, Issue 5, 2017, Pages 533-540

  Makoveichuk, Elena ^a   Vorrsjö, Evelina ^a   Olivecrona, Thomas ^a   Olivecrona, Gunilla ^a  

^a UMEÅ UNIVERSITY   (Sweden)

Author keywords

3T3 L1 adipocytes; Actinomycin D; Angiopoietin like protein 4; Foxo1 inhibitor; Lipoprotein lipase; TNF

Indexed keywords

ANGIOPOIETIN; ANGIOPOIETIN LIKE PROTEIN 4; DACTINOMYCIN; LIPOPROTEIN LIPASE; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; 5-AMINO-7-(CYCLOHEXYLAMINO)-1-ETHYL-6-FLUORO-4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID; ANGPTL4 PROTEIN, MOUSE; FOXO1 PROTEIN, MOUSE; MESSENGER RNA; QUINOLONE DERIVATIVE; TRANSCRIPTION FACTOR FKHR;

3T3 CELL LINE; ADIPOCYTE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; UPREGULATION; 3T3-L1 CELL LINE; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; RNA INTERFERENCE; TRANSCRIPTION INITIATION;

3T3-L1 CELLS; ADIPOCYTES; ANGIOPOIETINS; ANIMALS; DACTINOMYCIN; FORKHEAD BOX PROTEIN O1; GENE EXPRESSION REGULATION; LIPOPROTEIN LIPASE; MICE; QUINOLONES; RNA INTERFERENCE; RNA, MESSENGER; TRANSCRIPTIONAL ACTIVATION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 85013275740     PISSN: 13881981     EISSN: 18792618     Source Type: Journal    
DOI: 10.1016/j.bbalip.2017.02.005     Document Type: Article

References (36)

1. [1] Kersten, S., Physiological regulation of lipoprotein lipase. Biochim. Biophys. Acta 1841 (2014), 919–933.
2. [2] Young, S.G., Zechner, R., Biochemistry and pathophysiology of intravascular and intracellular lipolysis. Genes Dev. 27 (2013), 459–484.
3. [3] Kroupa, O., Vorrsjo, E., Stienstra, R., Mattijssen, F., Nilsson, S.K., Sukonina, V., Kersten, S., Olivecrona, G., Olivecrona, T., Linking nutritional regulation of Angptl4, Gpihbp1, and Lmf1 to lipoprotein lipase activity in rodent adipose tissue. BMC Physiol., 12, 2012, 13.
4. [4] Sukonina, V., Lookene, A., Olivecrona, T., Olivecrona, G., Angiopoietin-like protein 4 converts lipoprotein lipase to inactive monomers and modulates lipase activity in adipose tissue. Proc. Natl. Acad. Sci. U. S. A. 103 (2006), 17450–17455.
5. [5] Makoveichuk, E., Vorrsjo, E., Olivecrona, T., Olivecrona, G., Inactivation of lipoprotein lipase in 3T3-L1 adipocytes by angiopoietin-like protein 4 requires that both proteins have reached the cell surface. Biochem. Biophys. Res. Commun. 441 (2013), 941–946.
6. [6] Beutler, B., Mahoney, J., Le Trang, N., Pekala, P., Cerami, A., Purification of cachectin, a lipoprotein lipase-suppressing hormone secreted by endotoxin-induced RAW 264.7 cells. J. Exp. Med. 161 (1985), 984–995.
7. [7] Kawakami, M., Murase, T., Ogawa, H., Ishibashi, S., Mori, N., Takaku, F., Shibata, S., Human recombinant TNF suppresses lipoprotein lipase activity and stimulates lipolysis in 3T3-L1 cells. J. Biochem. 101 (1987), 331–338.
8. [8] Price, S.R., Olivecrona, T., Pekala, P.H., Regulation of lipoprotein lipase synthesis in 3T3-L1 adipocytes by cachectin. Further proof for identity with tumour necrosis factor. Biochem. J. 240 (1986), 601–604.
9. [9] Cornelius, P., Enerback, S., Bjursell, G., Olivecrona, T., Pekala, P.H., Regulation of lipoprotein lipase mRNA content in 3T3-L1 cells by tumour necrosis factor. Biochem. J. 249 (1988), 765–769.
10. [10] Barcia, A.M., Harris, H.W., Triglyceride-rich lipoproteins as agents of innate immunity. Clin. Infect. Dis. 41:Suppl. 7 (2005), S498–S503.
11. [11] Fogarty, C.L., Nieminen, J.K., Peraneva, L., Lassenius, M.I., Ahola, A.J., Taskinen, M.R., Jauhiainen, M., Kirveskari, J., Pussinen, P., Horkko, S., Makinen, V.P., Gordin, D., Forsblom, C., Groop, P.H., Vaarala, O., Lehto, M., High-fat meals induce systemic cytokine release without evidence of endotoxemia-mediated cytokine production from circulating monocytes or myeloid dendritic cells. Acta Diabetol. 52 (2015), 315–322.
12. [12] Herieka, M., Erridge, C., High-fat meal induced postprandial inflammation. Mol. Nutr. Food Res. 58 (2014), 136–146.
13. [13] Glass, C.K., Olefsky, J.M., Inflammation and lipid signaling in the etiology of insulin resistance. Cell Metab. 15 (2012), 635–645.
14. [14] Zechner, R., Newman, T.C., Sherry, B., Cerami, A., Breslow, J.L., Recombinant human cachectin/tumor necrosis factor but not interleukin-1 alpha downregulates lipoprotein lipase gene expression at the transcriptional level in mouse 3T3-L1 adipocytes. Mol. Cell. Biol. 8 (1988), 2394–2401.
15. [15] Yamada, T., Ozaki, N., Kato, Y., Miura, Y., Oiso, Y., Insulin downregulates angiopoietin-like protein 4 mRNA in 3T3-L1 adipocytes. Biochem. Biophys. Res. Commun. 347 (2006), 1138–1144.
16. [16] Kuo, T., Chen, T.C., Yan, S., Foo, F., Ching, C., McQueen, A., Wang, J.C., Repression of glucocorticoid-stimulated angiopoietin-like 4 gene transcription by insulin. J. Lipid Res. 55 (2014), 919–928.
17. [17] Semenkovich, C.F., Wims, M., Noe, L., Etienne, J., Chan, L., Insulin regulation of lipoprotein lipase activity in 3T3-L1 adipocytes is mediated at posttranscriptional and posttranslational levels. J. Biol. Chem. 264 (1989), 9030–9038.
18. [18] Lim, C.Y., Hong, W., Han, W., Adiponectin is released via a unique regulated exocytosis pathway from a pre-formed vesicle pool on insulin stimulation. Biochem. J. 471 (2015), 381–389.
19. [19] Makoveichuk, E., Sukonina, V., Kroupa, O., Thulin, P., Ehrenborg, E., Olivecrona, T., Olivecrona, G., Inactivation of lipoprotein lipase occurs on the surface of THP-1 macrophages where oligomers of angiopoietin-like protein 4 are formed. Biochem. Biophys. Res. Commun. 425 (2012), 138–143.
20. [20] Olivecrona, T., Chernick, S.S., Bengtsson-Olivecrona, G., Garrison, M., Scow, R.O., Synthesis and secretion of lipoprotein lipase in 3T3-L1 adipocytes. Demonstration of inactive forms of lipase in cells. J. Biol. Chem. 262 (1987), 10748–10759.
21. [21] Nagashima, T., Shigematsu, N., Maruki, R., Urano, Y., Tanaka, H., Shimaya, A., Shimokawa, T., Shibasaki, M., Discovery of novel forkhead box O1 inhibitors for treating type 2 diabetes: improvement of fasting glycemia in diabetic db/db mice. Mol. Pharmacol. 78 (2010), 961–970.
22. [22] Lu, B., Moser, A., Shigenaga, J.K., Grunfeld, C., Feingold, K.R., The acute phase response stimulates the expression of angiopoietin like protein 4. Biochem. Biophys. Res. Commun. 391 (2010), 1737–1741.
23. [23] Dijk, W., Beigneux, A.P., Larsson, M., Bensadoun, A., Young, S.G., Kersten, S., Angiopoietin-like 4 promotes intracellular degradation of lipoprotein lipase in adipocytes. J. Lipid Res. 57 (2016), 1670–1683.
24. [24] Semb, H., Peterson, J., Tavernier, J., Olivecrona, T., Multiple effects of tumor necrosis factor on lipoprotein lipase in vivo. J. Biol. Chem. 262 (1987), 8390–8394.
25. [25] Gray, N.E., Lam, L.N., Yang, K., Zhou, A.Y., Koliwad, S., Wang, J.C., Angiopoietin-like 4 (Angptl4) protein is a physiological mediator of intracellular lipolysis in murine adipocytes. J. Biol. Chem. 287 (2012), 8444–8456.
26. [26] Feingold, K.R., Staprans, I., Memon, R.A., Moser, A.H., Shigenaga, J.K., Doerrler, W., Dinarello, C.A., Grunfeld, C., Endotoxin rapidly induces changes in lipid metabolism that produce hypertriglyceridemia: low doses stimulate hepatic triglyceride production while high doses inhibit clearance. J. Lipid Res. 33 (1992), 1765–1776.
27. [27] Gouni, I., Oka, K., Etienne, J., Chan, L., Endotoxin-induced hypertriglyceridemia is mediated by suppression of lipoprotein lipase at a post-transcriptional level. J. Lipid Res. 34 (1993), 139–146.
28. [28] Santulli, G., Angiopoietin-like proteins: a comprehensive look. Front. Endocrinol. (Lausanne), 5, 2014, 4.
29. [29] Dijk, W., Kersten, S., Regulation of lipid metabolism by angiopoietin-like proteins. Curr. Opin. Lipidol. 27 (2016), 249–256.
30. [30] Koliwad, S.K., Kuo, T., Shipp, L.E., Gray, N.E., Backhed, F., So, A.Y., Farese, R.V. Jr., Wang, J.C., Angiopoietin-like 4 (ANGPTL4, fasting-induced adipose factor) is a direct glucocorticoid receptor target and participates in glucocorticoid-regulated triglyceride metabolism. J. Biol. Chem. 284 (2009), 25593–25601.
31. [31] Ruge, T., Sukonina, V., Kroupa, O., Makoveichuk, E., Lundgren, M., Svensson, M.K., Olivecrona, G., Eriksson, J.W., Effects of hyperinsulinemia on lipoprotein lipase, angiopoietin-like protein 4, and glycosylphosphatidylinositol-anchored high-density lipoprotein binding protein 1 in subjects with and without type 2 diabetes mellitus. Metabolism 61 (2012), 652–660.
32. [32] Ertunc, M.E., Sikkeland, J., Fenaroli, F., Griffiths, G., Daniels, M.P., Cao, H., Saatcioglu, F., Hotamisligil, G.S., Secretion of fatty acid binding protein aP2 from adipocytes through a nonclassical pathway in response to adipocyte lipase activity. J. Lipid Res. 56 (2015), 423–434.
33. [33] Wu, G., Brouckaert, P., Olivecrona, T., Rapid downregulation of adipose tissue lipoprotein lipase activity on food deprivation: evidence that TNF-alpha is involved. Am. J. Physiol. Endocrinol. Metab. 286 (2004), E711–E717.
34. [34] Bouter, B., Geary, N., Langhans, W., Asarian, L., Diet-genotype interactions in the early development of obesity and insulin resistance in mice with a genetic deficiency in tumor necrosis factor-alpha. Metabolism 59 (2010), 1065–1073.
35. [35] Carbo, N., Costelli, P., Tessitore, L., Bagby, G.J., Lopez-Soriano, F.J., Baccino, F.M., Argiles, J.M., Anti-tumour necrosis factor-alpha treatment interferes with changes in lipid metabolism in a tumour cachexia model. Clin. Sci. (Lond.) 87 (1994), 349–355.
36. [36] Esser, N., Paquot, N., Scheen, A.J., Anti-inflammatory agents to treat or prevent type 2 diabetes, metabolic syndrome and cardiovascular disease. Expert Opin. Investig. Drugs 24 (2015), 283–307.