Activation of NLRP1 and NLRP3 inflammasomes contributed to cyclic stretch-induced pyroptosis and release of IL-1β in human periodontal ligament cells

Oncotarget

Volumn 7, Issue 42, 2016, Pages 68292-68302

  Zhao, Dan ^a,b   Wu, Yaqin ^a,b   Zhuang, Jiabao ^a,b   Xu, Chun ^a,b   Zhang, Fuqiang ^a,b  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b Shanghai Research Institute of Stomatology   (China)

Author keywords

Cyclic stretch; Human periodontal ligament cell; IL 1 ; Inflammasome; Pyroptosis

Indexed keywords

CRYOPYRIN; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; NLRP1 PROTEIN; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; NLRP1 PROTEIN, HUMAN; NLRP3 PROTEIN, HUMAN; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ADOLESCENT; APOPTOSIS; ARTICLE; CHILD; CONTROLLED STUDY; CYCLIC STRETCH; CYTOKINE RELEASE; HUMAN; HUMAN CELL; INFLAMMATION; PERIODONTAL LIGAMENT; PERIODONTAL LIGAMENT CELL; PERIODONTITIS; PROTEIN FUNCTION; PYROPTOSIS; SCHOOL CHILD; SIGNAL TRANSDUCTION; STRETCHING; CELL CULTURE; CYTOLOGY; GENE EXPRESSION; GENETICS; MECHANICAL STRESS; METABOLISM; WESTERN BLOTTING;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; APOPTOSIS REGULATORY PROTEINS; BLOTTING, WESTERN; CASPASE 1; CELLS, CULTURED; CHILD; GENE EXPRESSION; HUMANS; INFLAMMASOMES; INTERLEUKIN-1BETA; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; PERIODONTAL LIGAMENT; PYROPTOSIS; SIGNAL TRANSDUCTION; STRESS, MECHANICAL;

EID: 85013214749     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/ONCOTARGET.11944     Document Type: Article

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