Pro-inflammatory immune responses in leukocytes of premature infants exposed to maternal chorioamnionitis or funisitis

Pediatric Research

Volumn 81, Issue 2, 2017, Pages 384-390

  Jackson, Courtney M ^a   Wells, Casey B ^a   Tabangin, Meredith E ^b   Meinzen Derr, Jareen ^b   Jobe, Alan H ^c   Chougnet, Claire A ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^c UNIVERSITY OF CINCINNATI   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FORKHEAD TRANSCRIPTION FACTOR; GAMMA INTERFERON; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; MESSENGER RNA; RETINOID RELATED ORPHAN RECEPTOR GAMMA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 3; TUMOR NECROSIS FACTOR; CYTOKINE;

ARTICLE; BLOOD; BLOOD VOLUME; CHORIOAMNIONITIS; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FOLLOW UP; FUNISITIS; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INFANT; LEUKOCYTE; LUNG DYSPLASIA; MALE; PREMATURITY; PRIORITY JOURNAL; CYTOLOGY; GENE EXPRESSION REGULATION; IMMUNOLOGY; INFLAMMATION; NEWBORN; PREGNANCY; TH17 CELL;

BRONCHOPULMONARY DYSPLASIA; CHORIOAMNIONITIS; CYTOKINES; FEMALE; GENE EXPRESSION REGULATION; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; INFLAMMATION; MALE; PREGNANCY; TH17 CELLS; TRANSCRIPTION FACTORS;

EID: 85012919179     PISSN: 00313998     EISSN: 15300447     Source Type: Journal    
DOI: 10.1038/pr.2016.232     Document Type: Article

References (34)

1. Maródi L. Innate cellular immune responses in newborns. Clin Immunol 2006;118:137-44.
2. Adkins B, Leclerc C, Marshall-Clarke S. Neonatal adaptive immunity comes of age. Nat Rev Immunol 2004;4:553-64.
3. Mold JE, McCune JM. Immunological tolerance during fetal development: from mouse to man. Adv Immunol 2012;115:73-111.
4. Miller LH, Haynes JD, McAulife FM, Shiroishi T, Durocher JR, McGin-niss MH. Evidence for diferences in erythrocyte surface receptors for the malarial parasites, Plasmodium falciparum and Plasmodium knowlesi. J Exp Med 1977;146:277-81.
5. Mold JE, Venkatasubrahmanyam S, Burt TD, et al. Fetal and adult hema-topoietic stem cells give rise to distinct T cell lineages in humans. Science 2010;330:1695-9.
6. Zhang X, Mozeleski B, Lemoine S, et al. CD4 T cells with effector memory phenotype and function develop in the sterile environment of the fetus. Sci Transl Med 2014;6:238ra72.
7. Hazenberg MD, Spits H. Human innate lymphoid cells. Blood 2014;124:700-9.
8. Ivarsson MA, Loh L, Marquardt N, et al. Diferentiation and functional regulation of human fetal NK cells. J Clin Invest 2013;123:3889-901.
9. Leeansyah E, Loh L, Nixon DF, Sandberg JK. Acquisition of innate-like microbial reactivity in mucosal tissues during human fetal MAIT-cell development. Nat Commun 2014;5:3143.
10. Eichenwald EC, Stark AR. Management and outcomes of very low birth weight. N Engl J Med 2008;358:1700-11.
11. Goldenberg RL, Culhane JF, Iams JD, Romero R. Epidemiology and causes of preterm birth. Lancet 2008;371:75-84.
12. Romero R, Gotsch F, Pineles B, Kusanovic JP. Infammation in pregnancy: its roles in reproductive physiology, obstetrical complications, and fetal injury. Nutr Rev 2007;65(12 Pt 2):S194-202.
13. Stoll BJ, Hansen NI, Higgins RD, et al.; National Institute of Child Health and Human Development. Very low birth weight preterm infants with early onset neonatal sepsis: the predominance of gram-negative infections continues in the National Institute of Child Health and Human Development Neonatal Research Network, 2002-2003. Pediatr Infect Dis J 2005;24:635-9.
14. Gomez R, Romero R, Ghezzi F, Yoon BH, Mazor M, Berry SM. The fetal infammatory response syndrome. Am J Obstet Gynecol 1998;179:194-202.
15. Kallapur SG, Nitsos I, Moss TJ, et al. IL-1 mediates pulmonary and systemic infammatory responses to chorioamnionitis induced by lipopoly-saccharide. Am J Respir Crit Care Med 2009;179:955-61.
16. Wolfs TG, Buurman WA, Zoer B, et al. Endotoxin induced chorioamnio-nitis prevents intestinal development during gestation in fetal sheep. PLoS One 2009;4:e5837.
17. Kemp M W, Saito M, Nitsos I, Jobe AH, Kallapur SG, Newnham J P. Exposure to in utero lipopolysaccharide induces infammation in the fetal ovine skin. Reprod Sci 2011;18:88-98.
18. Kallapur SG, Presicce P, Rueda CM, Jobe AH, Chougnet CA. Fetal immune response to chorioamnionitis. Semin Reprod Med 2014;32:56-67.
19. Daegelmann C, Herberth G, Röder S, et al.; LISAplus study group. Association between suppressors of cytokine signalling, T-helper type 1/T-helper type 2 balance and allergic sensitization in children. Clin Exp Allergy 2008;38:438-48.
20. Herberth G, Daegelmann C, Weber A, et al.; LISAplus Study Group. Association of neuropeptides with T1/T2 balance and allergic sensitization in children. Clin Exp Allergy 2006;36:1408-16.
21. Shennan AT, Dunn MS, Ohlsson A, Lennox K, Hoskins EM. Abnormal pulmonary outcomes in premature infants: prediction from oxygen requirement in the neonatal period. Pediatrics 1988;82:527-32.
22. Redline R W, Faye-Petersen O, Heller D, Qureshi F, Savell V, Vogler C; Society for Pediatric Pathology, Perinatal Section, Amniotic Fluid Infection Nosology Committee. Amniotic infection syndrome: nosology and repro-ducibility of placental reaction patterns. Pediatr Dev Pathol 2003;6:435-48.
23. Pryhuber GS, Maitre NL, Ballard RA, et al.; Prematurity and Respiratory Outcomes Program Investigators. Prematurity and respiratory outcomes program (PROP): study protocol of a prospective multicenter study of respiratory outcomes of preterm infants in the United States. BMC Pediatr 2015;15:37.
24. Gantert M, Been J V, Gavilanes AW, Garnier Y, Zimmermann LJ, Kramer BW. Chorioamnionitis: a multiorgan disease of the fetus? J Perina-tol 2010;30 Suppl:S21-30.
25. Misra RS, Shah S, Fowell DJ, et al. Preterm cord blood CD4? T cells exhibit increased IL-6 production in chorioamnionitis and decreased CD4? T cells in bronchopulmonary dysplasia. Hum Immunol 2015;76:329-38.
26. Cosmi L, De Palma R, Santarlasci V, et al. Human interleukin 17-pro-ducing cells originate from a CD161+CD4+ T cell precursor. J Exp Med 2008;205:1903-16.
27. Nishimaki S, Shima Y, Sato M, An H, Kadota K, Yokota S. Postnatal changes of cytokines in premature infants with or without funisitis. J Matern Fetal Neonatal Med 2014;27:1545-9.
28. Kallapur SG, Presicce P, Senthamaraikannan P, et al. Intra-amniotic IL-1β induces fetal infammation in rhesus monkeys and alters the regulatory T cell/IL-17 balance. J Immunol 2013;191:1102-9.
29. Matsuoka T, Matsubara T, Katayama K, Takeda K, Koga M, Furukawa S. Increase of cord blood cytokine-producing T cells in intrauterine infection. Pediatr Int 2001;43:453-7.
30. Romero R, Chaemsaithong P, Korzeniewski SJ, et al. Clinical chorioamnio-nitis at term II: the intra-amniotic infammatory response. J Perinat Med 2016;44:5-22.
31. Baier RJ, Loggins J, Kruger TE. Interleukin-4 and 13 concentrations in infants at risk to develop Bronchopulmonary Dysplasia. BMC Pediatr 2003;3:8.
32. Sempowski GD, Beckmann M P, Derdak S, Phipps R P. Subsets of murine lung fbroblasts express membrane-bound and soluble IL-4 receptors. Role of IL-4 in enhancing fbroblast proliferation and collagen synthesis. J Immunol 1994;152:3606-14.
33. Turunen R, Vaarala O, Nupponen I, et al. Activation of T cells in preterm infants with respiratory distress syndrome. Neonatology 2009;96:248-58.
34. Ivanov II, McKenzie BS, Zhou L, et al. The orphan nuclear receptor ROR-gammat directs the diferentiation program of proinfammatory IL-17+ T helper cells. Cell 2006;126:1121-33.