Patterns of Sociodemographic and Clinicopathologic Characteristics of Stages II and III Colorectal Cancer Patients by Age: Examining Potential Mechanisms of Young-Onset Disease

Journal of Cancer Epidemiology

Volumn 2017, Issue , 2017, Pages

  Murphy, Caitlin C ^a,b   Sanoff, Hanna K ^c   Stitzenberg, Karyn B ^c   Baron, John A ^b,d   Lund, Jennifer L ^b   Sandler, Robert S ^b,d  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b University of North Carolina at Chapel Hill   (United States)

^c UNIVERSITY OF NORTH CAROLINA   (United States)

^d UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT;

ADULT; AGE; AGED; ARTICLE; BLACK PERSON; CANCER CHEMOTHERAPY; CANCER LOCALIZATION; CANCER PATIENT; CANCER RADIOTHERAPY; CANCER STAGING; CANCER SURGERY; COLON RESECTION; COLORECTAL CANCER; COLORECTAL CARCINOMA; CONTROLLED STUDY; FEMALE; HISPANIC; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; MICROSATELLITE INSTABILITY; MULTIMODALITY CANCER THERAPY; PROCTOCOLECTOMY; RACE DIFFERENCE; RECTUM RESECTION; SIGNET RING CARCINOMA; TOTAL COLON RESECTION;

EID: 85012164853     PISSN: 16878558     EISSN: 16878566     Source Type: Journal    
DOI: 10.1155/2017/4024580     Document Type: Article

References (56)

1. R. L. Siegel, A. Jemal, and E. M. Ward, "Increase in incidence of colorectal cancer among young men and women in the United States," Cancer Epidemiology Biomarkers and Prevention, vol. 18, no. 6, pp. 1695-1698, 2009.
2. T. L. Fairley, C. J. Cardinez, J. Martin et al. , "Colorectal cancer in U. S. adults younger than 50 years of age, 1998-2001," Cancer, vol. 107, S5, pp. 1153-1161, 2006.
3. C. E. Bailey, C.-Y. Hu, Y. N. You et al. , "Increasing disparities in the age-related incidences of colon and rectal cancers in the United States, 1975-2010," JAMA Surgery, vol. 150, no. 1, pp. 17-22, 2015.
4. B. Karsten, J. Kim, J. King, and R. R. Kumar, "Characteristics of colorectal cancer in young patients at an urban county hospital," American Surgeon, vol. 74, no. 10, pp. 973-976, 2008.
5. K. Marble, S. Banerjee, and L. Greenwald, "Colorectal carcinoma in young patients," Journal of Surgical Oncology, vol. 51, no. 3, pp. 179-182, 1992.
6. N. Savas, U. Dagli, S. Akbulut, O. Yuksel, and B. Sahin, "Colorectal cancer localization in young patients: should we expand the screening program"DigestiveDiseases and Sciences, vol. 52, no. 3, pp. 798-802, 2007.
7. E. Mitry, A.-M. Benhamiche, J.-L. Jouve, F. Clinard, C. Finn-Faivre, and J. Faivre, "Colorectal adenocarcinoma in patients under 45 years of age: comparison with older patients in a welldefined French population," Diseases of the Colon and Rectum, vol. 44, no. 3, pp. 380-387, 2001.
8. J. Brant Parramore, J. P. Wei, and K. A. Yeh, "Colorectal cancer in patients under forty: presentation and outcome," American Surgeon, vol. 64, no. 6, pp. 563-568, 1998.
9. V. S. Schellerer, S. Merkel, S. C. Schumann et al. , "Despite aggressive histopathology survival is not impaired in young patients with colorectal cancer: CRC in patients under 50 years of age," International Journal of Colorectal Disease, vol. 27, no. 1, pp. 71-79, 2012.
10. R. K. Yantiss, M. Goodarzi, X. K. Zhou et al. , "Clinical, pathologic, and molecular features of early-onset colorectal carcinoma," American Journal of Surgical Pathology, vol. 33, no. 4, pp. 572-582, 2009.
11. J.-M. Chiang, M.-C. Chen, C. R. Changchien et al. , "Favorable influence of age on tumor characteristics of sporadic colorectal adenocarcinoma: patients 30 years of age or younger may be a distinct patient group," Diseases of the Colon and Rectum, vol. 46, no. 7, pp. 904-910, 2003.
12. C.-L. Chou, S.-C. Chang, T.-C. Lin et al. , "Differences in clinicopathological characteristics of colorectal cancer between younger and elderly patients: an analysis of 322 patients from a single institution," American Journal of Surgery, vol. 202, no. 5, pp. 574-582, 2011.
13. S. Ganapathi, D. Kumar, N. Katsoulas et al. , "Colorectal cancer in the young: trends, characteristics and outcome," International Journal of Colorectal Disease, vol. 26, no. 7, pp. 927-934, 2011.
14. P. M. Griffin, J. M. Liff, R. S. Greenberg, and W. S. Clark, "Adenocarcinomas of the colon and rectum in persons under 40 years old. A population-based study," Gastroenterology, vol. 100, no. 4, pp. 1033-1040, 1991.
15. M. Li, J.-Y. Li, A.-L. Zhao, and J. Gu, "Do young patients with colorectal cancer have a poorer prognosis than old patients" Journal of Surgical Research, vol. 167, no. 2, pp. 231-236, 2011.
16. J. T. Liang, K. C. Huang, A. L. Cheng, Y. M. Jeng, M. S. Wu, and S. M. Wang, "Clinicopathological and molecular biological features of colorectal cancer in patients less than 40 years of age," British Journal of Surgery, vol. 90, no. 2, pp. 205-214, 2003.
17. L. C. Harlan, L. X. Clegg, J. Abrams, J. L. Stevens, and R. Ballard-Barbash, "Community-based use of chemotherapy and hormonal therapy for early-stage breast cancer: 1987-2000," Journal of Clinical Oncology, vol. 24, no. 6, pp. 872-877, 2006.
18. L. C. Harlan, C. N. Klabunde, A. H. Ambs et al. , "Comorbidities, therapy, and newly diagnosed conditions for women with early stage breast cancer," Journal of Cancer Survivorship, vol. 3, no. 2, pp. 89-98, 2009.
19. J. A. Zujewski, L. C. Harlan, D. M. Morrell, and J. L. Stevens, "Ductal carcinoma in situ: trends in treatment over time in the US," Breast Cancer Research and Treatment, vol. 127, no. 1, pp. 251-257, 2011.
20. D. P. Cronin, L. C. Harlan, A. L. Potosky, L. X. Clegg, J. L. Stevens, and M. M. Mooney, "Patterns of care for adjuvant therapy in a random population-based sample of patients diagnosed with colorectal cancer," American Journal of Gastroenterology, vol. 101, no. 10, pp. 2308-2318, 2006.
21. C. C. Murphy, L. C. Harlan, J. L. Lund, C. F. Lynch, and A. M. Geiger, "Patterns of colorectal cancer care in the United States: 1990-2010," Journal of the National Cancer Institute, vol. 107, no. 10, Article ID djv198, 2015.
22. C. C. Murphy, L. C. Harlan, J. L. Warren, and A. M. Geiger, "Race and insurance differences in the receipt of adjuvant chemotherapy among patients with stage III colon cancer," Journal of Clinical Oncology, vol. 33,no. 23, pp. 2530-2536, 2015.
23. A. L. Potosky, L. C. Harlan, R. S. Kaplan, K. A. Johnson, and C. F. Lynch, "Age, sex, and racial differences in the use of standard adjuvant therapy for colorectal cancer," Journal of Clinical Oncology, vol. 20, no. 5, pp. 1192-1202, 2002.
24. E. L. Trimble, L. C. Harlan, D. Gius, J. Stevens, and S. M. Schwartz, "Patterns of care for women with cervical cancer in the United States," Cancer, vol. 113, no. 4, pp. 743-749, 2008.
25. K. Yost, C. Perkins, R. Cohen, C. Morris, and W. Wright, "Socioeconomic status and breast cancer incidence in California for different race/ethnic groups," Cancer Causes and Control, vol. 12, no. 8, pp. 703-711, 2001.
26. M. Yu, Z. Tatalovich, J. T. Gibson, and K. A. Cronin, "Using a composite index of socioeconomic status to investigate health disparitieswhile protecting the confidentiality of cancer registry data," Cancer Causes and Control, vol. 25, no. 1, pp. 81-92, 2014.
27. U. S. Department of Health and Human Services, Health Resources and Services Administration, and Bureau of Health Professions, Area Health Resource File (AHRF), http://ahrf. hrsa. gov/.
28. D. J. Weisenberger, A. J. Levine, T. I. Long et al. , "Association of the colorectalCpGislandmethylator phenotypewithmolecular features, risk factors, and family history," Cancer Epidemiology Biomarkers and Prevention, vol. 24, no. 3, pp. 512-519, 2015.
29. M. E. Stokes, C. S. Davis, and G. G. Koch, Categorical Data Analysis Using SAS , SAS Institute, 2012.
30. F. A. Sinicrope, Q. Shi, T. C. Smyrk et al. , "Molecular markers identify subtypes of stage III colon cancer associated with patient outcomes," Gastroenterology, vol. 148, no. 1, pp. 88-99, 2015.
31. The Cancer Genome Atlas Network, "Comprehensive molecular characterization of human colon and rectal cancer," Nature, vol. 487, no. 7407, pp. 330-337, 2012.
32. J. Guinney, R. Dienstmann, X. Wang et al. , "The consensus molecular subtypes of colorectal cancer," Nature Medicine, vol. 21, no. 11, pp. 1350-1356, 2015.
33. H. H. Yoon, Q. Shi, S. R. Alberts et al. , "Racial differences in BRAF/KRAS mutation rates and survival in stage III colon cancer patients," Journal of theNational Cancer Institute, vol. 107, no. 10, 2015.
34. K. Kumar, H. Brim, F. Giardiello et al. , "Distinct BRAF (V600E) and KRAS mutations in high microsatellite Instability sporadic colorectal cancer in African Americans," Clinical Cancer Research, vol. 15, no. 4, pp. 1155-1161, 2009.
35. B. E. Sylvester, D. Huo, A. Khramtsov et al. , "Molecular analysis of colorectal tumors within a diverse patient cohort at a single institution," Clinical Cancer Research, vol. 18, no. 2, pp. 350-359, 2012.
36. A. Umar, C. R. Boland, J. P. Terdiman et al. , "Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability," Journal of the National Cancer Institute, vol. 96, no. 4, pp. 261-268, 2004.
37. A. B. Benson III, T. Bekaii-Saab, E. Chan et al. , "Rectal cancer," JNCCN Journal of the National Comprehensive Cancer Network, vol. 10, no. 12, pp. 1528-1564, 2012.
38. A. B. Benson, A. P. Venook, T. Bekaii-Saab et al. , "Colon cancer, version 3. 2014," Journal of the National Comprehensive Cancer Network, vol. 12, no. 7, pp. 1028-1059, 2014.
39. L. C. Beamer, M. L. Grant, C. R. Espenschied et al. , "Reflex immunohistochemistry and microsatellite instability testing of colorectal tumors for lynch syndrome among US cancer programs and follow-up of abnormal results," Journal of Clinical Oncology, vol. 30, no. 10, pp. 1058-1063, 2012.
40. K. Kessels, H. H. Fidder, N. L. De Groot et al. , "Adherence to microsatellite instability testing in young-onset colorectal cancer patients," Diseases of the Colon and Rectum, vol. 56, no. 7, pp. 825-833, 2013.
41. J. J. Karlitz, M.-C. Hsieh, Y. Liu et al. , "Population-based lynch syndrome screening by microsatellite instability in patients 50: prevalence, testing determinants, and result availability prior to colon surgery," American Journal of Gastroenterology, vol. 110, no. 7, pp. 948-955, 2015.
42. T. André, C. Boni, L. Mounedji-Boudiaf et al. , "Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer," New England Journal of Medicine, vol. 350, no. 23, pp. 2343-2351, 2004.
43. C. Twelves, A. Wong, M. P. Nowacki et al. , "Capecitabine as adjuvant treatment for stage III colon cancer," The New England Journal of Medicine, vol. 352, no. 26, pp. 2696-2704, 2005.
44. F. Paraf and S. Jothy, "Colorectal cancer before the age of 40: a case-control study," Diseases of the Colon and Rectum, vol. 43, no. 9, pp. 1222-1226, 2000.
45. H. M. Quah, R. Joseph, D. Schrag et al. , "Young age influences treatment but not outcome of colon cancer," Annals of Surgical Oncology, vol. 14, no. 10, pp. 2759-2765, 2007.
46. P. J. Kneuertz, G. J. Chang, C.-Y. Hu et al. , "Overtreatment of young adults with colon cancer: more intense treatments with unmatched survival gains," JAMA Surgery, vol. 150, no. 5, pp. 402-409, 2015.
47. C. H. Lieu, L. A. Renfro, A. De Gramont et al. , "Association of age with survival in patients with metastatic colorectal cancer: analysis from the ARCAD clinical trials program," Journal of Clinical Oncology, vol. 32, no. 27, pp. 2975-2982, 2014.
48. H. L. Howe, X. Wu, L. A. G. Ries et al. , "Annual report to the nation on the status of cancer, 1975-2003, featuring cancer among U. S. Hispanic/Latino populations," Cancer, vol. 107, no. 8, pp. 1711-1742, 2006.
49. S. R. Ennis, M. Ŕos-Vargas, and N. G. Albert, Census USBot: The Hispanic Population: 2010: US Department of Commerce, Economics and Statistics Administration, US Census Bureau, 2011.
50. American Cancer Society,Cancer Facts & Figures forHispanics, American Cancer Society, Atlanta, Ga, USA, 2009.
51. P. S. Pinheiro, R. L. Sherman, E. J. Trapido et al. , "Cancer incidence in first generation U. S. Hispanics: Cubans, Mexicans, Puerto Ricans, and New Latinos," Cancer Epidemiology Biomarkers and Prevention, vol. 18, no. 8, pp. 2162-2169, 2009.
52. R. L. Siegel, A. Jemal, M. J. Thun, Y. Hao, and E. M. Ward, "Trends in the incidence of colorectal cancer in relation to county-level poverty among blacks and whites," Journal of the National Medical Association, vol. 100, no. 12, pp. 1441-1444, 2008.
53. E. Ward, A. Jemal, V. Cokkinides et al. , "Cancer disparities by race/ethnicity and socioeconomic status," Ca-A Cancer Journal for Clinicians, vol. 54, no. 2, pp. 78-93, 2004.
54. C. A. Doubeni, T. S. Field, D. S. M. Buist et al. , "Racial differences in tumor stage and survival for colorectal cancer in an insured population," Cancer, vol. 109, no. 3,pp. 612-620, 2007.
55. X. L. Du, S. Fang, S. W. Vernon et al. , "Racial disparities and socioeconomic status in association with survival in a large population-based cohort of elderly patients with colon cancer," Cancer, vol. 110, no. 3, pp. 660-669, 2007.
56. P. J. Limburg, W. S. Harmsen, H. H. Chen et al. , "revalence of alterations in DNA mismatch repair genes in patients with young-onset colorectal cancer," Clinical Gastroenterology and Hepatology, vol. 9, no. 6, pp. 497-502, 2011.