Prevalence of Alterations in DNA Mismatch Repair Genes in Patients With Young-Onset Colorectal Cancer

Clinical Gastroenterology and Hepatology

Volumn 9, Issue 6, 2011, Pages 497-502

  Limburg, Paul J ^a   Harmsen, William S ^a   Chen, Helen H ^a   Gallinger, Steven ^b   Haile, Robert W ^c   Baron, John A ^d   Casey, Graham ^c   Woods, Michael O ^e   Thibodeau, Stephen N ^a   Lindor, Noralane M ^a  

^a MAYO CLINIC   (United States)

^b CANCER CARE ONTARIO   (Canada)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^d DARTMOUTH MEDICAL SCHOOL   (United States)

^e MEMORIAL UNIVERSITY OF NEWFOUNDLAND   (Canada)

Author keywords

Cancer Genetics; Colon Cancer; Genetics; Mutation Analysis

Indexed keywords

MISMATCH REPAIR PROTEIN; PROTEIN MLH1; PROTEIN MSH2; PROTEIN MSH6;

ADULT; ARTICLE; BASE MISPAIRING; CANCER SCREENING; COLORECTAL CANCER; FEMALE; GENE MUTATION; GENE SEQUENCE; GERM LINE; HEREDITARY NONPOLYPOSIS COLORECTAL CANCER; HIGH RISK POPULATION; HUMAN; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; MISMATCH REPAIR; NUCLEOTIDE SEQUENCE; ONSET AGE; PREDICTIVE VALUE; PREVALENCE; SENSITIVITY AND SPECIFICITY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADULT; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; DNA MISMATCH REPAIR; DNA-BINDING PROTEINS; FEMALE; GENE DELETION; GENE DUPLICATION; GENETIC TESTING; HUMANS; MALE; MIDDLE AGED; MUTATION; MUTS HOMOLOG 2 PROTEIN; NUCLEAR PROTEINS; PREDICTIVE VALUE OF TESTS; PREVALENCE; SENSITIVITY AND SPECIFICITY; SEQUENCE ANALYSIS, DNA;

EID: 79957469844     PISSN: 15423565     EISSN: 15423565     Source Type: Journal    
DOI: 10.1016/j.cgh.2010.10.021     Document Type: Article

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