-
1
-
-
2642709177
-
Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators
-
Palella FJ Jr, Delaney KM, Moorman AC, et al. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators. N Engl J Med 1998;338:853-60.
-
(1998)
N Engl J Med
, vol.338
, pp. 853-860
-
-
Palella, F.J.1
Delaney, K.M.2
Moorman, A.C.3
-
2
-
-
0032576426
-
Changing patterns of mortality across Europe in patients infected with HIV-1
-
Mocroft A, Vella S, Benfield TL, et al. Changing patterns of mortality across Europe in patients infected with HIV-1. EuroSIDA Study Group. Lancet 1998;352:1725-30.
-
(1998)
EuroSIDA Study Group. Lancet
, vol.352
, pp. 1725-1730
-
-
Mocroft, A.1
Vella, S.2
Benfield, T.L.3
-
3
-
-
65449167169
-
Effect of early versus deferred antiretroviral therapy for HIV on survival
-
Kitahata MM, Gange SJ, Abraham AG, et al. Effect of early versus deferred antiretroviral therapy for HIV on survival. N Engl J Med 2009;360:1815-26.
-
(2009)
N Engl J Med
, vol.360
, pp. 1815-1826
-
-
Kitahata, M.M.1
Gange, S.J.2
Abraham, A.G.3
-
4
-
-
80755172498
-
Premature aging and premature age-related comorbidities in HIV-infected patients: Facts and hypotheses
-
Capeau J. Premature aging and premature age-related comorbidities in HIV-infected patients: facts and hypotheses. Clin Infect Dis 2011;53: 1127-9.
-
(2011)
Clin Infect Dis
, vol.53
, pp. 1127-1129
-
-
Capeau, J.1
-
5
-
-
84855616052
-
-
Panel on Antiretroviral Guidelines for Adults and Adolescents Department of Health and Human Services. Accessed October 15, 2013
-
Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents. Department of Health and Human Services. Available at http://www.aidsinfo.nih.gov/ContentFiles/AdultandAdolescentGL.pdf. Accessed October 15, 2013.
-
Guidelines for the Use of Antiretroviral Agents in HIV-1-infected Adults and Adolescents
-
-
-
6
-
-
79954611097
-
Tenofovir-associated kidney toxicity in HIV-infected patients: A review of the evidence
-
Hall AM, Hendry BM, Nitsch D, et al. Tenofovir-associated kidney toxicity in HIV-infected patients: a review of the evidence. Am J Kidney Dis 2011;57:773-80.
-
(2011)
Am J Kidney Dis
, vol.57
, pp. 773-780
-
-
Hall, A.M.1
Hendry, B.M.2
Nitsch, D.3
-
7
-
-
77956637582
-
Randomized comparison of renal effects, efficacy, and safety with once-daily abacavir/lamivudine versus tenofovir/emtricitabine, administered with efavirenz, in antiretroviralnaive, HIV-1-infected adults: 48-week results from the ASSERT study
-
Post FA, Moyle GJ, StellbrinkHJ, et al. Randomized comparison of renal effects, efficacy, and safety with once-daily abacavir/lamivudine versus tenofovir/emtricitabine, administered with efavirenz, in antiretroviralnaive, HIV-1-infected adults: 48-week results from the ASSERT study. J Acquir Immune Defic Syndr 2010;55:49-57.
-
(2010)
J Acquir Immune Defic Syndr
, vol.55
, pp. 49-57
-
-
Post, F.A.1
Moyle, G.J.2
Stellbrink, H.J.3
-
9
-
-
77957847133
-
Comparison of changes in bone density and turnover with abacavir-lamivudine versus tenofovir- emtricitabine in HIV-infected adults: 48-week results from the ASSERT study
-
Stellbrink HJ, Orkin C, Arribas JR, et al. Comparison of changes in bone density and turnover with abacavir-lamivudine versus tenofovir- emtricitabine in HIV-infected adults: 48-week results from the ASSERT study. Clin Infect Dis 2010;51:963-72.
-
(2010)
Clin Infect Dis
, vol.51
, pp. 963-972
-
-
Stellbrink, H.J.1
Orkin, C.2
Arribas, J.R.3
-
11
-
-
50949121086
-
Chronic administration of tenofovir to rhesus macaques from infancy through adulthood and pregnancy: Summary of pharmacokinetics and biological and virological effects
-
Van Rompay KK, Durand-Gasselin L, Brignolo LL, et al. Chronic administration of tenofovir to rhesus macaques from infancy through adulthood and pregnancy: summary of pharmacokinetics and biological and virological effects. Antimicrob Agents Chemother 2008;52: 3144-60.
-
(2008)
Antimicrob Agents Chemother
, vol.52
, pp. 3144-3160
-
-
Van Rompay, K.K.1
Durand-Gasselin, L.2
Brignolo, L.L.3
-
12
-
-
18244398917
-
Selective intracellular activation of a novel prodrug of the human immunodeficiency virus reverse transcriptase inhibitor tenofovir leads to preferential distribution and accumulation in lymphatic tissue
-
Lee WA, He GX, Eisenberg E, et al. Selective intracellular activation of a novel prodrug of the human immunodeficiency virus reverse transcriptase inhibitor tenofovir leads to preferential distribution and accumulation in lymphatic tissue. Antimicrob Agents Chemother 2005;49: 1898-906.
-
(2005)
Antimicrob Agents Chemother
, vol.49
, pp. 1898-1906
-
-
Lee, W.A.1
He, G.X.2
Eisenberg, E.3
-
13
-
-
45749091322
-
Activation of 9-[(R)-2-[[(S)-[[(S)-1- (Isopropoxycarbonyl) ethyl]amino]phenoxyphosphinyl]-methoxy] propyl] adenine (GS-7340) and other tenofovir phosphonoamidate prodrugs by human proteases
-
Birkus G, Kutty N, He GX, et al. Activation of 9-[(R)-2-[[(S)-[[(S)-1- (Isopropoxycarbonyl) ethyl]amino]phenoxyphosphinyl]-methoxy] propyl] adenine (GS-7340) and other tenofovir phosphonoamidate prodrugs by human proteases. Mol Pharmacol 2008;74:92-100.
-
(2008)
Mol Pharmacol
, vol.74
, pp. 92-100
-
-
Birkus, G.1
Kutty, N.2
He, G.X.3
-
14
-
-
84937215233
-
Tenofovir alafenamide versus tenofovir disoproxil fumarate, coformulated with elvitegravir, cobicistat, and emtricitabine, for initial treatment of HIV-1 infection: Two randomised, double-blind, phase 3, non-inferiority trials
-
Sax PE, Wohl D, Yin MT, et al. Tenofovir alafenamide versus tenofovir disoproxil fumarate, coformulated with elvitegravir, cobicistat, and emtricitabine, for initial treatment of HIV-1 infection: two randomised, double-blind, phase 3, non-inferiority trials. Lancet 2015;385:2606-15.
-
(2015)
Lancet
, vol.385
, pp. 2606-2615
-
-
Sax, P.E.1
Wohl, D.2
Yin, M.T.3
-
15
-
-
84937531121
-
Tenofovir alafenamide versus tenofovir disoproxil fumarate in the first protease inhibitor-based singletablet regimen for initial HIV-1 therapy: A randomized phase 2 study
-
Mills A, Crofoot GJr, McDonald C, et al. Tenofovir alafenamide versus tenofovir disoproxil fumarate in the first protease inhibitor-based singletablet regimen for initial HIV-1 therapy: a randomized phase 2 study. J Acquir Immune Defic Syndr 2015;69:439-45.
-
(2015)
J Acquir Immune Defic Syndr
, vol.69
, pp. 439-445
-
-
Mills, A.1
Crofoot, G.2
McDonald, C.3
-
16
-
-
84906080271
-
Tenofovir alafenamide vs. Tenofovir disoproxil fumarate in single tablet regimens for initial HIV-1 therapy: A randomized phase 2 study
-
Sax PE, Zolopa A, Brar I, et al. Tenofovir alafenamide vs. tenofovir disoproxil fumarate in single tablet regimens for initial HIV-1 therapy: a randomized phase 2 study. J Acquir Immune Defic Syndr 2014;67:52-8.
-
(2014)
J Acquir Immune Defic Syndr
, vol.67
, pp. 52-58
-
-
Sax, P.E.1
Zolopa, A.2
Brar, I.3
-
17
-
-
84960824872
-
Efficacy and safety of tenofovir alafenamide versus tenofovir disoproxil fumarate given as fixed-dose combinations containing emtricitabine as backbones for treatment of HIV-1 infection in virologically suppressed adults: A randomised, doubleblind, active-controlled phase 3 trial
-
Gallant JE, Daar ES, Raffi F, et al. Efficacy and safety of tenofovir alafenamide versus tenofovir disoproxil fumarate given as fixed-dose combinations containing emtricitabine as backbones for treatment of HIV-1 infection in virologically suppressed adults: a randomised, doubleblind, active-controlled phase 3 trial. Lancet HIV 2016;3:e158-165.
-
(2016)
Lancet HIV
, vol.3
, pp. e158-e165
-
-
Gallant, J.E.1
Daar, E.S.2
Raffi, F.3
-
18
-
-
85028245571
-
Switching from tenofovir disoproxil fumarate to tenofovir alafenamide in antiretroviral regimens for virologically suppressed adults with HIV-1 infection: A randomised, active-controlled, multicentre, open-label, phase 3, noninferiority study
-
Mills A, Arribas JR, Andrade-Villanueva J, et al. Switching from tenofovir disoproxil fumarate to tenofovir alafenamide in antiretroviral regimens for virologically suppressed adults with HIV-1 infection: a randomised, active-controlled, multicentre, open-label, phase 3, noninferiority study. Lancet Infect Dis 2016;16:43-52.
-
(2016)
Lancet Infect Dis
, vol.16
, pp. 43-52
-
-
Mills, A.1
Arribas, J.R.2
Andrade-Villanueva, J.3
-
19
-
-
84973121361
-
Brief report: A randomized, doubleblind comparison of tenofovir alafenamide versus tenofovir disoproxil fumarate, each coformulated with elvitegravir, cobicistat, and emtricitabine for initial HIV-1 treatment: Week 96 results
-
Wohl D, Oka S, Clumeck N, et al. Brief report: a randomized, doubleblind comparison of tenofovir alafenamide versus tenofovir disoproxil fumarate, each coformulated with elvitegravir, cobicistat, and emtricitabine for initial HIV-1 treatment: week 96 results. J Acquir Immune Defic Syndr 2016;72:58-64.
-
(2016)
J Acquir Immune Defic Syndr
, vol.72
, pp. 58-64
-
-
Wohl, D.1
Oka, S.2
Clumeck, N.3
-
20
-
-
84865719940
-
Switching to tenofovir/emtricitabine from abacavir/lamivudine in HIV-infected adults with raised cholesterol: Effect on lipid profiles
-
Behrens G, Maserati R, Rieger A, et al. Switching to tenofovir/emtricitabine from abacavir/lamivudine in HIV-infected adults with raised cholesterol: effect on lipid profiles. Antivir Ther 2012;17: 1011-20.
-
(2012)
Antivir Ther
, vol.17
, pp. 1011-1020
-
-
Behrens, G.1
Maserati, R.2
Rieger, A.3
-
21
-
-
77954319572
-
A pilot study to determine the impact on dyslipidemia of adding tenofovir to stable background antiretroviral therapy: ACTG 5206
-
TungsiripatM, Kitch D, Glesby MJ, et al. A pilot study to determine the impact on dyslipidemia of adding tenofovir to stable background antiretroviral therapy: ACTG 5206. AIDS 2010;24:1781-4.
-
(2010)
AIDS
, vol.24
, pp. 1781-1784
-
-
Tungsiripat, M.1
Kitch, D.2
Glesby, M.J.3
-
22
-
-
84907817074
-
British HIV Association guidelines for the treatment of HIV-1-positive adults with antiretroviral therapy 2012
-
Williams I, Churchill D, Anderson J, et al. British HIV Association guidelines for the treatment of HIV-1-positive adults with antiretroviral therapy 2012. HIV Med 2012;13(suppl 2):1-85.
-
(2012)
HIV Med
, vol.13
, pp. 1-85
-
-
Williams, I.1
Churchill, D.2
Anderson, J.3
-
23
-
-
80755123417
-
Premature age-related comorbidities among HIV-infected persons compared with the general population
-
Guaraldi G, Orlando G, Zona S, et al. Premature age-related comorbidities among HIV-infected persons compared with the general population. Clin Infect Dis 2011;53:1120-6.
-
(2011)
Clin Infect Dis
, vol.53
, pp. 1120-1126
-
-
Guaraldi, G.1
Orlando, G.2
Zona, S.3
-
24
-
-
77957847133
-
Comparison of changes in bone density and turnover with abacavir-lamivudine versus tenofoviremtricitabine in HIV-infected adults: 48-week results from the ASSERT study
-
Stellbrink HJ, Orkin C, Arribas JR, et al. Comparison of changes in bone density and turnover with abacavir-lamivudine versus tenofoviremtricitabine in HIV-infected adults: 48-week results from the ASSERT study. Clin Infect Dis 2010;51:963-72.
-
(2010)
Clin Infect Dis
, vol.51
, pp. 963-972
-
-
Stellbrink, H.J.1
Orkin, C.2
Arribas, J.R.3
-
25
-
-
79957494036
-
Bone mineral density and fractures in antiretroviral-naive persons randomized to receive abacavirlamivudine or tenofovir disoproxil fumarate-emtricitabine along with efavirenz or atazanavir-ritonavir: AIDS Clinical Trials Group A5224s, a substudy of ACTG A5202
-
McComsey GA, Kitch D, Daar ES, et al. Bone mineral density and fractures in antiretroviral-naive persons randomized to receive abacavirlamivudine or tenofovir disoproxil fumarate-emtricitabine along with efavirenz or atazanavir-ritonavir: Aids Clinical Trials Group A5224s, a substudy of ACTG A5202. J Infect Dis 2011;203:1791-801.
-
(2011)
J Infect Dis
, vol.203
, pp. 1791-1801
-
-
McComsey, G.A.1
Kitch, D.2
Daar, E.S.3
-
26
-
-
84884501365
-
Bone mineral density in HIV participants randomized to raltegravir and lopinavir/ritonavir compared with standard second line therapy
-
Martin A, Moore C, Mallon PW, et al. Bone mineral density in HIV participants randomized to raltegravir and lopinavir/ritonavir compared with standard second line therapy. AIDS 2013;27:2403-11.
-
(2013)
AIDS
, vol.27
, pp. 2403-2411
-
-
Martin, A.1
Moore, C.2
Mallon, P.W.3
-
27
-
-
58149494675
-
Tenofovir use is associated with an increase in serum alkaline phosphatase in the Swiss HIV Cohort Study
-
Fux CA, Rauch A, Simcock M, et al. Tenofovir use is associated with an increase in serum alkaline phosphatase in the Swiss HIV Cohort Study. Antivir Ther 2008;13:1077-82.
-
(2008)
Antivir Ther
, vol.13
, pp. 1077-1082
-
-
Fux, C.A.1
Rauch, A.2
Simcock, M.3
-
28
-
-
33749499825
-
An update on biomarkers of bone turnover and their utility in biomedical research and clinical practice
-
Leeming DJ, Alexandersen P, Karsdal MA, et al. An update on biomarkers of bone turnover and their utility in biomedical research and clinical practice. Eur J Clin Pharmacol 2006;62:781-92.
-
(2006)
Eur J Clin Pharmacol
, vol.62
, pp. 781-792
-
-
Leeming, D.J.1
Alexandersen, P.2
Karsdal, M.A.3
-
29
-
-
19944434212
-
Association between renal disease and outcomes among HIV-infected women receiving or not receiving antiretroviral therapy
-
Szczech LA, Hoover DR, Feldman JG, et al. Association between renal disease and outcomes among HIV-infected women receiving or not receiving antiretroviral therapy. Clin Infect Dis 2004;39:1199-206.
-
(2004)
Clin Infect Dis
, vol.39
, pp. 1199-1206
-
-
Szczech, L.A.1
Hoover, D.R.2
Feldman, J.G.3
-
30
-
-
77958470109
-
Cystatin C, albuminuria, and 5-year all-cause mortality in HIV-infected persons
-
Choi A, Scherzer R, Bacchetti P, et al. Cystatin C, albuminuria, and 5-year all-cause mortality in HIV-infected persons. Am J Kidney Dis 2010;56:872-82.
-
(2010)
Am J Kidney Dis
, vol.56
, pp. 872-882
-
-
Choi, A.1
Scherzer, R.2
Bacchetti, P.3
-
31
-
-
76649132688
-
Association between kidney function and albuminuria with cardiovascular events in HIV-infected persons
-
Choi AI, Li Y, Deeks SG, et al. Association between kidney function and albuminuria with cardiovascular events in HIV-infected persons. Circulation 2010;121:651-8.
-
(2010)
Circulation
, vol.121
, pp. 651-658
-
-
Choi, A.I.1
Li, Y.2
Deeks, S.G.3
-
32
-
-
77956634614
-
Microalbuminuria is associated with all-cause and AIDS mortality in womenwith HIV infection
-
Wyatt CM, Hoover DR, Shi Q, et al. Microalbuminuria is associated with all-cause and AIDS mortality in womenwith HIV infection. J Acquir Immune Defic Syndr 2010;55:73-7.
-
(2010)
J Acquir Immune Defic Syndr
, vol.55
, pp. 73-77
-
-
Wyatt, C.M.1
Hoover, D.R.2
Shi, Q.3
-
33
-
-
84865714929
-
Effect of cobicistat on glomerular filtration rate in subjects with normal and impaired renal function
-
German P, Liu HC, Szwarcberg J, et al. Effect of cobicistat on glomerular filtration rate in subjects with normal and impaired renal function. J Acquir Immune Defic Syndr 2012;61:32-40.
-
(2012)
J Acquir Immune Defic Syndr
, vol.61
, pp. 32-40
-
-
German, P.1
Liu, H.C.2
Szwarcberg, J.3
-
34
-
-
84920111540
-
Tenofovir alafenamide is not a substrate for renal organic anion transporters (OATs) and does not exhibit OATdependent cytotoxicity
-
Bam RA, Yant SR, Cihlar T. Tenofovir alafenamide is not a substrate for renal organic anion transporters (OATs) and does not exhibit OATdependent cytotoxicity. Antivir Ther 2014;19:687-92.
-
(2014)
Antivir Ther
, vol.19
, pp. 687-692
-
-
Bam, R.A.1
Yant, S.R.2
Cihlar, T.3
-
35
-
-
84883234363
-
Depletion of the cellular antioxidant system contributes to tenofovir disoproxil fumarate- induced mitochondrial damage and increased oxido-nitrosative stress in the kidney
-
Abraham P, Ramamoorthy H, Isaac B. Depletion of the cellular antioxidant system contributes to tenofovir disoproxil fumarate- induced mitochondrial damage and increased oxido-nitrosative stress in the kidney. J Biomed Sci 2013;20:61.
-
(2013)
J Biomed Sci
, vol.20
, pp. 61
-
-
Abraham, P.1
Ramamoorthy, H.2
Isaac, B.3
-
37
-
-
84892409297
-
Use of glomerular filtration rate estimating equations for drug dosing in HIV-positive patients
-
Okparavero AA, Tighiouart H, Krishnasami Z, et al. Use of glomerular filtration rate estimating equations for drug dosing in HIV-positive patients. Antivir Ther 2013;18:793-802.
-
(2013)
Antivir Ther
, vol.18
, pp. 793-802
-
-
Okparavero, A.A.1
Tighiouart, H.2
Krishnasami, Z.3
|