Depletion of the cellular antioxidant system contributes to tenofovir disoproxil fumarate - Induced mitochondrial damage and increased oxido-nitrosative stress in the kidney

Journal of Biomedical Science

Volumn 20, Issue 1, 2013, Pages

  Abraham, Premila ^a   Ramamoorthy, Hemalatha ^a   Isaac, Bina ^a  

^a CHRISTIAN MEDICAL COLLEGE   (India)

Author keywords

Mitochondrial antioxidant system; Mitochondrial damage; Proximal tubular damage; Tenofovir

Indexed keywords

3 NITROTYROSINE; ANTIOXIDANT; CARBONATE DEHYDRATASE; CARBONYL DERIVATIVE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; NITRATE; SUCCINATE DEHYDROGENASE; SUPEROXIDE DISMUTASE; TENOFOVIR DISOPROXIL; THIOBARBITURIC ACID REACTIVE SUBSTANCE; ADENINE; DRUG DERIVATIVE; GLUTATHIONE; MANGANESE SUPEROXIDE DISMUTASE; PHOSPHONIC ACID DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME ACTIVITY; FANCONI RENOTUBULAR SYNDROME; HUMAN; HUMAN TISSUE; KIDNEY PARENCHYMA; MALE; MITOCHONDRION; NEPHROTOXICITY; NITROSATIVE STRESS; NONHUMAN; OXIDATIVE STRESS; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEINURIA; RAT; TUBULAR DYSFUNCTION; ANIMAL; CHEMICALLY INDUCED DISORDER; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DRUG EFFECT; ENZYMOLOGY; GENETICS; INJURY; KIDNEY; KIDNEY PROXIMAL TUBULE; METABOLISM; PATHOLOGY; WISTAR RAT; ANALOGS AND DERIVATIVES; CHEMICALLY INDUCED; DRUG EFFECTS;

ADENINE; ANIMALS; ANTIOXIDANTS; GLUTATHIONE; GLUTATHIONE PEROXIDASE; KIDNEY; KIDNEY TUBULES, PROXIMAL; MITOCHONDRIA; MITOCHONDRIAL DISEASES; ORGANOPHOSPHONATES; OXIDATIVE STRESS; RATS; RATS, WISTAR; SUPEROXIDE DISMUTASE;

EID: 84883234363     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1186/1423-0127-20-61     Document Type: Article

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