-
1
-
-
0038210300
-
Open Innovation: The New Imperative for Creating and Profiting from Technology
-
Harvard Business School Press Boston
-
1 Chesbrough, H.W., Open Innovation: The New Imperative for Creating and Profiting from Technology. 2003, Harvard Business School Press, Boston.
-
(2003)
-
-
Chesbrough, H.W.1
-
2
-
-
84908035484
-
New Frontiers in Open Innovation
-
Oxford University Press
-
2 Chesbrough, H.W., Vanhaverbeke, W., West, J., New Frontiers in Open Innovation. 2014, Oxford University Press.
-
(2014)
-
-
Chesbrough, H.W.1
Vanhaverbeke, W.2
West, J.3
-
3
-
-
75949093281
-
Is open innovation the way forward for big pharma?
-
3 Hunter, J., Stephens, S., Is open innovation the way forward for big pharma?. Nat. Rev. Drug Discov. 9 (2010), 87–88.
-
(2010)
Nat. Rev. Drug Discov.
, vol.9
, pp. 87-88
-
-
Hunter, J.1
Stephens, S.2
-
4
-
-
77957352907
-
Organisational modes for Open Innovation in the bio-pharmaceutical industry: an exploratory analysis
-
4 Bianchi, M., et al. Organisational modes for Open Innovation in the bio-pharmaceutical industry: an exploratory analysis. Technovation 31 (2011), 22–33.
-
(2011)
Technovation
, vol.31
, pp. 22-33
-
-
Bianchi, M.1
-
5
-
-
80052831391
-
Drug discovery in the next decade: innovation needed ASAP
-
5 Bennani, Y.L., Drug discovery in the next decade: innovation needed ASAP. Drug Discov. Today 16 (2011), 779–792.
-
(2011)
Drug Discov. Today
, vol.16
, pp. 779-792
-
-
Bennani, Y.L.1
-
6
-
-
84866739808
-
Drug discovery in pharmaceutical industry: productivity challenges and trends
-
6 Khanna, I., Drug discovery in pharmaceutical industry: productivity challenges and trends. Drug Discov. Today 17 (2012), 1088–1102.
-
(2012)
Drug Discov. Today
, vol.17
, pp. 1088-1102
-
-
Khanna, I.1
-
7
-
-
84889024686
-
Models for open innovation in the pharmaceutical industry
-
7 Schuhmacher, A., et al. Models for open innovation in the pharmaceutical industry. Drug Discov. Today 18 (2013), 1133–1137.
-
(2013)
Drug Discov. Today
, vol.18
, pp. 1133-1137
-
-
Schuhmacher, A.1
-
8
-
-
84898998993
-
Collaboration for innovation is the new mantra for the pharmaceutical industry. Spring 14
-
8 Hunter, J., Collaboration for innovation is the new mantra for the pharmaceutical industry. Spring 14. Drug Discov. World, 2014 (http://www.ddw-online.com).
-
(2014)
Drug Discov. World
-
-
Hunter, J.1
-
9
-
-
84928978237
-
University-industry collaborations: models, drivers and cultures
-
9 Ehrismann, D., Patel, D.D., University-industry collaborations: models, drivers and cultures. Swiss Med. Wkly., 2015, 10.4414/smw.2015.14086 (http://www.smw.ch/content/smw-2015-14086/).
-
(2015)
Swiss Med. Wkly.
-
-
Ehrismann, D.1
Patel, D.D.2
-
10
-
-
84936846249
-
Crowdsourcing in pharma: a strategic framework
-
10 Bentzien, J., et al. Crowdsourcing in pharma: a strategic framework. Drug Discov. Today, 2015, 10.1016/j.drudis.2015.01.011.
-
(2015)
Drug Discov. Today
-
-
Bentzien, J.1
-
11
-
-
84969508638
-
Open innovation in early drug discovery: roadmaps and roadblocks
-
11 Reichman, M., Simpson, P.B., Open innovation in early drug discovery: roadmaps and roadblocks. Drug Discov. Today, 2015, 10.1016/j.drudis.2015.12.008.
-
(2015)
Drug Discov. Today
-
-
Reichman, M.1
Simpson, P.B.2
-
12
-
-
84973410020
-
A new chapter in innovation
-
12 Holmes, D., A new chapter in innovation. Nature 533 (2016), S54–S55.
-
(2016)
Nature
, vol.533
, pp. S54-S55
-
-
Holmes, D.1
-
13
-
-
85019323840
-
Executing an Open Innovation Model: Cooperation is Key to Competition for Biopharmaceutical Companies
-
Deloitte website, Accessed 6 September
-
13 Executing an Open Innovation Model: Cooperation is Key to Competition for Biopharmaceutical Companies; Deloitte website, Accessed 6 September 2016, http://www2.deloitte.com/content/dam/Deloitte/us/Documents/life-sciences-health-care/us-lshc-open-innovation.pdf.
-
(2016)
-
-
-
14
-
-
4344645978
-
Can the pharmaceutical industry reduce attrition rates?
-
14 Kola, I., Landis, J., Can the pharmaceutical industry reduce attrition rates?. Nat. Rev. Drug Discov. 3 (2004), 711–716.
-
(2004)
Nat. Rev. Drug Discov.
, vol.3
, pp. 711-716
-
-
Kola, I.1
Landis, J.2
-
15
-
-
84857743319
-
Diagnosing the decline in pharmaceutical R&D efficiency
-
15 Scannell, J.W., et al. Diagnosing the decline in pharmaceutical R&D efficiency. Nat. Rev. Drug Discov. 11 (2012), 191–200.
-
(2012)
Nat. Rev. Drug Discov.
, vol.11
, pp. 191-200
-
-
Scannell, J.W.1
-
16
-
-
84959128138
-
Innovation in the pharmaceutical industry: new estimates of R&D costs
-
16 DiMasi, J.A., et al. Innovation in the pharmaceutical industry: new estimates of R&D costs. J. Health Economics 47 (2016), 20–33.
-
(2016)
J. Health Economics
, vol.47
, pp. 20-33
-
-
DiMasi, J.A.1
-
17
-
-
79951967029
-
Principles of early drug discovery
-
17 Hughes, J.P., et al. Principles of early drug discovery. Br. J. Pharmacol., 2010, 10.1111/j.1476-5381.2010.01127.x (http://onlinelibrary.wiley.com).
-
(2010)
Br. J. Pharmacol.
-
-
Hughes, J.P.1
-
18
-
-
85019329014
-
-
OIDD website, Accessed September
-
18 Research & Development in the Pharmaceutical Industry, OIDD website, Accessed September, 2016. https://openinnovation.lilly.com/dd/includes/pdf/R_and_D_White_Paper_Final.pdf.
-
(2016)
-
-
Research & Development in the Pharmaceutical Industry1
-
19
-
-
84923103029
-
Measuring open innovation in the bio-pharmaceutical industry
-
19 Michelino, F., et al. Measuring open innovation in the bio-pharmaceutical industry. Creativity Innovation Manage., 2015, 10.1111/caim.12072 (http://onlinelibrary.wiley.com).
-
(2015)
Creativity Innovation Manage.
-
-
Michelino, F.1
-
20
-
-
84996886657
-
Measuring open innovation: a toolkit for successful innovation teams
-
20 Erkens, M., et al. Measuring open innovation: a toolkit for successful innovation teams. Performance 6 (2014), 12–23.
-
(2014)
Performance
, vol.6
, pp. 12-23
-
-
Erkens, M.1
-
21
-
-
85019307976
-
OIDD website
-
What is OIDD? Accessed September
-
21 OIDD website, What is OIDD? https://openinnovation.lilly.com/dd/what-is-oidd/ Accessed September, 2016.
-
(2016)
-
-
-
22
-
-
79951886664
-
The story of Eli Lilly's open innovation journey: how one company developed a mature model
-
22 Schwartz, K., Huff, B., The story of Eli Lilly's open innovation journey: how one company developed a mature model. PDMA Visions 34 (2010), 19–22.
-
(2010)
PDMA Visions
, vol.34
, pp. 19-22
-
-
Schwartz, K.1
Huff, B.2
-
23
-
-
85019320100
-
Innovation Without Walls: Alliance Management at Eli Lilly and Company
-
Harvard Business Review
-
23 Lyles, M., Lai, Y., Dhanaraj, C., Innovation Without Walls: Alliance Management at Eli Lilly and Company. 2007, Harvard Business Review.
-
(2007)
-
-
Lyles, M.1
Lai, Y.2
Dhanaraj, C.3
-
24
-
-
84925285086
-
A decade of innovation in pharmaceutical R&D: the chorus model
-
24 Owens, P.K., et al. A decade of innovation in pharmaceutical R&D: the chorus model. Nat. Rev. Drug Discov. 14 (2015), 17–28.
-
(2015)
Nat. Rev. Drug Discov.
, vol.14
, pp. 17-28
-
-
Owens, P.K.1
-
25
-
-
79960537049
-
2 assay panel
-
2 assay panel. J. Biomol. Screen. 16:6 (2011), 588–602.
-
(2011)
J. Biomol. Screen.
, vol.16
, Issue.6
, pp. 588-602
-
-
Lee, J.A.1
-
26
-
-
85019332932
-
-
Program Agreements
-
26 OIDD Website, Program Agreements, https://openinnovation.lilly.com/dd/getting-started/program-agreements.html.
-
-
-
Website, O.I.D.D.1
-
27
-
-
84968754250
-
Compound screening: fresh hunting ground
-
27 McGilvray, A., Compound screening: fresh hunting ground. Nature 533 (2016), S65–S67.
-
(2016)
Nature
, vol.533
, pp. S65-S67
-
-
McGilvray, A.1
-
28
-
-
85019307976
-
OIDD website
-
What We Offer, Accessed September
-
28 OIDD website, What We Offer, https://openinnovation.lilly.com/dd/what-we-offer/ Accessed September 2016.
-
(2016)
-
-
-
29
-
-
84894094150
-
Open innovation drug discovery (OIDD): a potential path to novel therapeutic chemical space
-
29 Alvim-Gaston, M., et al. Open innovation drug discovery (OIDD): a potential path to novel therapeutic chemical space. Curr. Topics Med. Chem. 14 (2014), 294–303.
-
(2014)
Curr. Topics Med. Chem.
, vol.14
, pp. 294-303
-
-
Alvim-Gaston, M.1
-
30
-
-
85019343657
-
Protecting Your Intellectual Property
-
30 OIDD Website, Protecting Your Intellectual Property, https://openinnovation.lilly.com/dd/what-is-oidd/protecting-your-intellectual-property.html.
-
-
-
Website, O.I.D.D.1
-
31
-
-
84908530414
-
Chemistry: Chemical Con Artists Foil Drug Discovery
-
Within Lilly, the term “confirmed active” excludes so-called PAIN compounds that interfere with assays or have promiscuous activity, thus over-inflating success rate. For an excellent description of PAINs, see, DOI
-
31 Within Lilly, the term “confirmed active” excludes so-called PAIN compounds that interfere with assays or have promiscuous activity, thus over-inflating success rate. For an excellent description of PAINs, see Baell J., Walters M.A. (2014) Chemistry: Chemical Con Artists Foil Drug Discovery. Nature 513(7519):481–3. DOI: 10.1038/513481a.
-
(2014)
Nature
, vol.513
, Issue.7519
, pp. 481-483
-
-
Baell, J.1
Walters, M.A.2
-
32
-
-
85019334372
-
-
Compound Acquisition
-
32 OIDD Website, Compound Acquisition, https://openinnovation.lilly.com/dd/what-we-offer/compound-acquisition.html.
-
-
-
Website, O.I.D.D.1
|