메뉴 건너뛰기




Volumn 8, Issue JAN, 2017, Pages

Clinical review of antidiabetic drugs: Implications for type 2 diabetes mellitus management

(16)  Chaudhury, Arun a   Duvoor, Chitharanjan a,b   Reddy Dendi, Vijaya Sena c   Kraleti, Shashank b   Chada, Aditya a,b   Ravilla, Rahul a,b   Marco, Asween a,d   Shekhawat, Nawal Singh a,e   Montales, Maria Theresa b   Kuriakose, Kevin f   Sasapu, Appalanaidu b   Beebe, Alexandria g   Patil, Naveen g   Musham, Chaitanya K h   Lohani, Govinda Prasad i   Mirza, Wasique j  


Author keywords

Chronic; Clinical management; Diabetes; Insulin; Primary care

Indexed keywords

ANTIDIABETIC AGENT; BIGUANIDE; EXENDIN 4; HEMOGLOBIN A1C; INCRETIN; INSULIN; LIRAGLUTIDE; MEGLITINIDE; METFORMIN; PIOGLITAZONE; ROSIGLITAZONE;

EID: 85011846490     PISSN: None     EISSN: 16642392     Source Type: Journal    
DOI: 10.3389/fendo.2017.0006     Document Type: Short Survey
Times cited : (965)

References (51)
  • 1
    • 84959282357 scopus 로고    scopus 로고
    • London: National Institute for Health and Care Excellence
    • Internal Clinical Guidelines Team. Type 2 Diabetes in Adults: Management. London: National Institute for Health and Care Excellence (2015). 28 p.
    • (2015) Type 2 Diabetes in Adults: Management , pp. 28
  • 2
    • 84960878943 scopus 로고    scopus 로고
    • Standards of medical care in diabetes-2016: summary of revisions
    • Standards of medical care in diabetes-2016: summary of revisions. Diabetes Care (2016) 39(Suppl 1):S4-5. doi:10.2337/dc16-S003.
    • (2016) Diabetes Care , vol.39 , pp. S4-S5
  • 3
    • 84892649479 scopus 로고    scopus 로고
    • Standards of medical care in diabetes
    • American Diabetes Association. Standards of medical care in diabetes. Diabetes Care (2014) 37(1):514-80. doi:10.2337/dc14-S014.
    • (2014) Diabetes Care , vol.37 , Issue.1 , pp. 514-580
  • 4
    • 84877747085 scopus 로고    scopus 로고
    • Diabetes and HIV: current understanding and future perspectives
    • Kalra S, Agrawal N. Diabetes and HIV: current understanding and future perspectives. Curr Diab Rep (2013) 13(3):419-27. doi:10.1007/s11892-013-0369-9.
    • (2013) Curr Diab Rep , vol.13 , Issue.3 , pp. 419-427
    • Kalra, S.1    Agrawal, N.2
  • 5
    • 67650702822 scopus 로고    scopus 로고
    • Effect of statins on fasting plasma glucose in diabetic and nondiabetic patients
    • Sukhija R, Prayaga S, Marashdeh M, Bursac Z, Kakar P, Bansal D, et al. Effect of statins on fasting plasma glucose in diabetic and nondiabetic patients. J Investig Med (2009) 57(3):495-9. doi:10.2310/JIM.0b013e318197ec8b.
    • (2009) J Investig Med , vol.57 , Issue.3 , pp. 495-499
    • Sukhija, R.1    Prayaga, S.2    Marashdeh, M.3    Bursac, Z.4    Kakar, P.5    Bansal, D.6
  • 6
    • 84958053119 scopus 로고    scopus 로고
    • Preventing new-onset diabetes in thiazide-treated patients
    • Mancia G. Preventing new-onset diabetes in thiazide-treated patients. Lancet Diabetes Endocrinol (2016) 4(2):90-2. doi:10.1016/S2213-8587(15)00391-5.
    • (2016) Lancet Diabetes Endocrinol , vol.4 , Issue.2 , pp. 90-92
    • Mancia, G.1
  • 8
    • 84964742402 scopus 로고    scopus 로고
    • Centers for Disease Control and Prevention. Diabetes Latest. (2014). Available from: www.cdc.gov/features/diabetesfactsheet.
    • (2014) Diabetes Latest
  • 10
    • 84908055590 scopus 로고    scopus 로고
    • DiabetesPro
    • American Diabetes Association. Fast Facts-Data and Statistics about Diabetes. DiabetesPro (2014). Available from: http://professional.diabetes.org/content/fast-facts-data-and-statistics-about-diabetes.
    • (2014) Fast Facts-Data and Statistics about Diabetes
  • 11
    • 85011912649 scopus 로고    scopus 로고
    • (2016). Available from: http://care.diabetesjournals.org/content/39/Supplement_1.
    • (2016)
  • 12
    • 84960439629 scopus 로고    scopus 로고
    • The evolution of diabetic ketoacidosis: an update of its etiology, pathogenesis and management
    • Nyenwe EA, Kitabchi AE. The evolution of diabetic ketoacidosis: an update of its etiology, pathogenesis and management. Metabolism (2016) 65(4):507-21. doi:10.1016/j.metabol.2015.12.007.
    • (2016) Metabolism , vol.65 , Issue.4 , pp. 507-521
    • Nyenwe, E.A.1    Kitabchi, A.E.2
  • 13
    • 0034641568 scopus 로고    scopus 로고
    • Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study
    • Stratton IM, Adler AI, Neil HA, Matthews DR, Manley SE, Cull CA, et al. Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study. BMJ (2000) 321:405-12. doi:10.1136/bmj.321.7258.405.
    • (2000) BMJ , vol.321 , pp. 405-412
    • Stratton, I.M.1    Adler, A.I.2    Neil, H.A.3    Matthews, D.R.4    Manley, S.E.5    Cull, C.A.6
  • 14
    • 85011912664 scopus 로고    scopus 로고
    • EMedicine health
    • Stoppler M, Shiel W. Hemoglobin A1C Test. EMedicine health. (2016). Available from: http://www.emedicinehealth.com/hemoglobin_a1c_hba1c/article_em.htm.
    • (2016) Hemoglobin A1C Test
    • Stoppler, M.1    Shiel, W.2
  • 16
    • 0004694873 scopus 로고    scopus 로고
    • For People of African, Mediterranean, or Southeast Asian Heritage: Important Information about Diabetes Blood Tests. National Institute of Diabetes and Digestive and Kidney Diseases (2011). Available from: http://www.niddk.nih.gov/health-information/health-topics/diagnostic-tests/people-african-mediterranean-southeast-asian-heritage-important-information-diabetes-blood-tests/Pages/index.aspx.
    • (2011) National Institute of Diabetes and Digestive and Kidney Diseases
  • 17
    • 85011912675 scopus 로고    scopus 로고
    • Clinical Diabetes
    • American Diabetes Association. Screening for Type 2 Diabetes. (Vol. 18). Clinical Diabetes (2000). Available from: http://journal.diabetes.org/clinicaldiabetes/v18n22000/pg69.htm.
    • (2000) Screening for Type 2 Diabetes , vol.18
  • 18
    • 84862302432 scopus 로고    scopus 로고
    • Prediabetes: a high risk state for developing diabetes
    • Tabak A, Herder C, Rathmann W, Brunner E, Kivimaki M. Prediabetes: a high risk state for developing diabetes. Lancet (2012) 379(9833):2279-90. doi:10.1016/S0140-6736(12)60283-9.
    • (2012) Lancet , vol.379 , Issue.9833 , pp. 2279-2290
    • Tabak, A.1    Herder, C.2    Rathmann, W.3    Brunner, E.4    Kivimaki, M.5
  • 19
    • 84929046598 scopus 로고    scopus 로고
    • Prediabetes and lifestyle modification: time to prevent a preventable disease
    • Tuso P. Prediabetes and lifestyle modification: time to prevent a preventable disease. Perm J (2014) 18(3):88-93. doi:10.7812/TPP/14-002.
    • (2014) Perm J , vol.18 , Issue.3 , pp. 88-93
    • Tuso, P.1
  • 20
    • 85011845404 scopus 로고    scopus 로고
    • Diabetes UK
    • Consumption of Carbohydrate in People with Diabetes. Diabetes UK. (2011). Available from: https://www.diabetes.org.uk/Professionals/Position-statements-reports/Food-nutrition-lifestyle/Consumption-of-carbohydrate-in-people-with-diabetes/.
    • (2011)
  • 21
    • 0025841841 scopus 로고
    • Effects of dietary fiber and carbohydrate on glucose and lipoprotein metabolism in diabetic patients
    • Riccardi G, Rivellese A. Effects of dietary fiber and carbohydrate on glucose and lipoprotein metabolism in diabetic patients. Diabetes Care (1991) 14(12):1115-25. doi:10.2337/diacare.14.12.1115.
    • (1991) Diabetes Care , vol.14 , Issue.12 , pp. 1115-1125
    • Riccardi, G.1    Rivellese, A.2
  • 22
    • 79955549960 scopus 로고    scopus 로고
    • Physical activity advice only or structured exercise training and association with HbA1c levels in type 2 diabetes: a systematic review and meta-analysis
    • Umpierre D, Ribeiro PA, Kramer CK, Leitão CB, Zucatti AT, Azevedo MJ, et al. Physical activity advice only or structured exercise training and association with HbA1c levels in type 2 diabetes: a systematic review and meta-analysis. JAMA (2011) 305(17):1790-9.
    • (2011) JAMA , vol.305 , Issue.17 , pp. 1790-1799
    • Umpierre, D.1    Ribeiro, P.A.2    Kramer, C.K.3    Leitão, C.B.4    Zucatti, A.T.5    Azevedo, M.J.6
  • 24
    • 64649104158 scopus 로고    scopus 로고
    • Banting Lecture. From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitus
    • Defronzo RA. Banting Lecture. From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitus. Diabetes (2009) 58(4):773-95. doi:10.2337/db09-9028.
    • (2009) Diabetes , vol.58 , Issue.4 , pp. 773-795
    • Defronzo, R.A.1
  • 25
    • 84943358575 scopus 로고    scopus 로고
    • The current drug treatment landscape for diabetes and perspectives for the future
    • Bailey CJ. The current drug treatment landscape for diabetes and perspectives for the future. Clin Pharmacol Ther (2015) 98(2):170-84. doi:10.1002/cpt.144.
    • (2015) Clin Pharmacol Ther , vol.98 , Issue.2 , pp. 170-184
    • Bailey, C.J.1
  • 26
    • 84964495115 scopus 로고    scopus 로고
    • PA-C diagnosis and management of diabetes: synopsis of the 2016; American Diabetes Association standards of medical care in diabetes
    • James JC, Andrew SR, Charles FS Jr, Annie N. PA-C diagnosis and management of diabetes: synopsis of the 2016; American Diabetes Association standards of medical care in diabetes. Ann Intern Med (2016) 164:542-52. doi:10.7326/M15-3016.
    • (2016) Ann Intern Med , vol.164 , pp. 542-552
    • James, J.C.1    Andrew, S.R.2    Charles, F.S.3    Annie, N.4
  • 27
    • 60449089649 scopus 로고    scopus 로고
    • Medical management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes
    • Nathan DM, Buse JB, Davidson MB, Ferrannini E, Holman RR, Sherwin R, et al. Medical management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care (2009) 32(1):193. doi:10.2337/dc08-9025.
    • (2009) Diabetes Care , vol.32 , Issue.1 , pp. 193
    • Nathan, D.M.1    Buse, J.B.2    Davidson, M.B.3    Ferrannini, E.4    Holman, R.R.5    Sherwin, R.6
  • 28
    • 84919999219 scopus 로고    scopus 로고
    • Management of hyperglycemia in type 2 diabetes, 2015: a patient-centered approach: update to a position statement of the American Diabetes Association and the European Association for the Study of Diabetes
    • Inzucchi SE, Bergenstal RM, Buse JB, Diamant M, Ferrannini E, Nauck M, et al. Management of hyperglycemia in type 2 diabetes, 2015: a patient-centered approach: update to a position statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care (2015) 38(1):140-9. doi:10.2337/dc14-2441.
    • (2015) Diabetes Care , vol.38 , Issue.1 , pp. 140-149
    • Inzucchi, S.E.1    Bergenstal, R.M.2    Buse, J.B.3    Diamant, M.4    Ferrannini, E.5    Nauck, M.6
  • 29
    • 84978976076 scopus 로고    scopus 로고
    • Comparison of clinical outcomes and adverse events associated with glucose-lowering drugs in patients with type 2 diabetes: a meta-analysis
    • Palmer SC, Mavridis D, Nicolucci A, Johnson DW, Tonelli M, Craig JC, et al. Comparison of clinical outcomes and adverse events associated with glucose-lowering drugs in patients with type 2 diabetes: a meta-analysis. JAMA (2016) 316(3):313-24. doi:10.1001/jama.2016.9400.
    • (2016) JAMA , vol.316 , Issue.3 , pp. 313-324
    • Palmer, S.C.1    Mavridis, D.2    Nicolucci, A.3    Johnson, D.W.4    Tonelli, M.5    Craig, J.C.6
  • 30
    • 85011927583 scopus 로고    scopus 로고
    • (2016). Available from: http://www.clevelandclinicmeded.com/medicalpubs/diseasemanagement/endocrinology/diabetes-mellitus-treatment/.
    • (2016)
  • 32
    • 84920025605 scopus 로고    scopus 로고
    • Metformin in patients with type 2 diabetes and kidney disease: a systematic review
    • Inzucchi SE, Lipska KJ, Mayo H, Bailey CJ, McGuire DK. Metformin in patients with type 2 diabetes and kidney disease: a systematic review. JAMA (2014) 312(24):2668-75. doi:10.1001/jama.2014.15298.
    • (2014) JAMA , vol.312 , Issue.24 , pp. 2668-2675
    • Inzucchi, S.E.1    Lipska, K.J.2    Mayo, H.3    Bailey, C.J.4    McGuire, D.K.5
  • 33
    • 84975705273 scopus 로고    scopus 로고
    • Vitamin B12 screening in metformin-treated diabetics in primary care: were elderly patients less likely to be tested?
    • Fogelman Y, Kitai E, Blumberg G, Golan-Cohen A, Rapoport M, Carmeli E. Vitamin B12 screening in metformin-treated diabetics in primary care: were elderly patients less likely to be tested? Aging Clin Exp Res (2016). doi:10.1007/s40520-016-0546-1.
    • (2016) Aging Clin Exp Res
    • Fogelman, Y.1    Kitai, E.2    Blumberg, G.3    Golan-Cohen, A.4    Rapoport, M.5    Carmeli, E.6
  • 34
    • 84884550328 scopus 로고    scopus 로고
    • Rationale and design of the glycemia reduction approaches in diabetes: a comparativeeffectiveness study (GRADE)
    • Nathan DM, Buse JB, Kahn SE, Krause-Steinrauf H, Larkin ME, Staten M, et al. Rationale and design of the glycemia reduction approaches in diabetes: a comparativeeffectiveness study (GRADE). Diabetes Care (2013) 36(8):2254-61. doi:10.2337/dc13-0356.
    • (2013) Diabetes Care , vol.36 , Issue.8 , pp. 2254-2261
    • Nathan, D.M.1    Buse, J.B.2    Kahn, S.E.3    Krause-Steinrauf, H.4    Larkin, M.E.5    Staten, M.6
  • 35
    • 84957665720 scopus 로고    scopus 로고
    • The incretin effect in healthy individuals and those with type 2 diabetes: physiology, pathophysiology, and response to therapeutic interventions
    • Nauck MA, Meier JJ. The incretin effect in healthy individuals and those with type 2 diabetes: physiology, pathophysiology, and response to therapeutic interventions. Lancet Diabetes Endocrinol (2016) 4(6):525-36. doi:10.1016/S2213-8587(15)00482-9.
    • (2016) Lancet Diabetes Endocrinol , vol.4 , Issue.6 , pp. 525-536
    • Nauck, M.A.1    Meier, J.J.2
  • 36
    • 84973472686 scopus 로고    scopus 로고
    • Diabetes medications as monotherapy or metformin-based combination therapy for type 2 diabetes: a systematic review and meta-analysis
    • Maruthur NM, Tseng E, Hutfless S, Wilson LM, Suarez-Cuervo C, Berger Z, et al. Diabetes medications as monotherapy or metformin-based combination therapy for type 2 diabetes: a systematic review and meta-analysis. Ann Intern Med (2016) 164(11):740-51. doi:10.7326/M15-2650.
    • (2016) Ann Intern Med , vol.164 , Issue.11 , pp. 740-751
    • Maruthur, N.M.1    Tseng, E.2    Hutfless, S.3    Wilson, L.M.4    Suarez-Cuervo, C.5    Berger, Z.6
  • 37
    • 84922816507 scopus 로고    scopus 로고
    • Efficacy and tolerability of glucagon-like peptide-1 receptor agonists in patients with type 2 diabetes mellitus
    • Harris KB, McCarty DJ. Efficacy and tolerability of glucagon-like peptide-1 receptor agonists in patients with type 2 diabetes mellitus. Ther Adv Endocrinol Metab (2015) 6(1):3-18. doi:10.1177/2042018814558242.
    • (2015) Ther Adv Endocrinol Metab , vol.6 , Issue.1 , pp. 3-18
    • Harris, K.B.1    McCarty, D.J.2
  • 38
    • 84885171560 scopus 로고    scopus 로고
    • The clinical efficacy and safety of sodium glucose cotransporter-2 inhibitors in adults with type 2diabetes mellitus
    • Riser Taylor S, Harris KB. The clinical efficacy and safety of sodium glucose cotransporter-2 inhibitors in adults with type 2diabetes mellitus. Pharmacotherapy (2013) 33(9):984-99. doi:10.1002/phar.1303.
    • (2013) Pharmacotherapy , vol.33 , Issue.9 , pp. 984-999
    • Riser Taylor, S.1    Harris, K.B.2
  • 39
    • 0032511566 scopus 로고    scopus 로고
    • Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34)
    • Erratum in: Lancet (1998) 352(9139):1558
    • UK Prospective Diabetes Study (UKPDS) Group. Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). Lancet (1998) 352(9131):854-65; Erratum in: Lancet (1998) 352(9139):1558. doi:10.1016/S0140-6736(98)07037-8.
    • (1998) Lancet , vol.352 , Issue.9131 , pp. 854-865
  • 41
    • 84862267597 scopus 로고    scopus 로고
    • Pathogenesis and glycemic management of type 2 diabetes mellitus: a physiological approach
    • Ismail-Beigi F. Pathogenesis and glycemic management of type 2 diabetes mellitus: a physiological approach. Arch Iran Med (2012) 15(4):239-46.
    • (2012) Arch Iran Med , vol.15 , Issue.4 , pp. 239-246
    • Ismail-Beigi, F.1
  • 42
    • 0036894342 scopus 로고    scopus 로고
    • Sulfonylurea stimulation of insulin secretion
    • Proks P, Reimann F, Green N, Gribble F, Ashcroft F. Sulfonylurea stimulation of insulin secretion. Diabetes (2002) 51(3):5368-76. doi:10.2337/diabetes.51.2007.S368.
    • (2002) Diabetes , vol.51 , Issue.3 , pp. 5368-5376
    • Proks, P.1    Reimann, F.2    Green, N.3    Gribble, F.4    Ashcroft, F.5
  • 44
    • 84865242528 scopus 로고    scopus 로고
    • Preventing diabetes mellitus in developing countries
    • Erratum in: Nat Rev Endocrinol (2012) 8(11):692
    • Echouffo-Tcheugui JB, Dagogo-Jack S. Preventing diabetes mellitus in developing countries. Nat Rev Endocrinol (2012) 8(9):557-62; Erratum in: Nat Rev Endocrinol (2012) 8(11):692. doi:10.1038/nrendo.2012.46.
    • (2012) Nat Rev Endocrinol , vol.8 , Issue.9 , pp. 557-562
    • Echouffo-Tcheugui, J.B.1    Dagogo-Jack, S.2
  • 45
    • 84923208538 scopus 로고    scopus 로고
    • Acquired immunodeficiencies and tuberculosis: focus on HIV/AIDS and diabetes mellitus
    • Ronacher K, Joosten SA, van Crevel R, Dockrell HM, Walzl G, Ottenhoff TH. Acquired immunodeficiencies and tuberculosis: focus on HIV/AIDS and diabetes mellitus. Immunol Rev (2015) 264(1):121-37. doi:10.1111/imr.12257.
    • (2015) Immunol Rev , vol.264 , Issue.1 , pp. 121-137
    • Ronacher, K.1    Joosten, S.A.2    van Crevel, R.3    Dockrell, H.M.4    Walzl, G.5    Ottenhoff, T.H.6
  • 46
    • 0032742992 scopus 로고    scopus 로고
    • The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus
    • Weyer C, Bogardus C, Mott DM, Pratley RE. The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus. J Clin Invest (1999) 104:787-94. doi:10.1172/JCI7231.
    • (1999) J Clin Invest , vol.104 , pp. 787-794
    • Weyer, C.1    Bogardus, C.2    Mott, D.M.3    Pratley, R.E.4
  • 47
    • 84982074515 scopus 로고    scopus 로고
    • Consensus statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the comprehensive type 2 diabetes management algorithm-2016 executive summary
    • Garber AJ, Abrahamson MJ, Barzilay JI, Blonde L, Bloomgarden ZT, Bush MA, et al. Consensus statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the comprehensive type 2 diabetes management algorithm-2016 executive summary. Endocr Pract (2016) 22(1):84-113. doi:10.4158/EP151126.CS.
    • (2016) Endocr Pract , vol.22 , Issue.1 , pp. 84-113
    • Garber, A.J.1    Abrahamson, M.J.2    Barzilay, J.I.3    Blonde, L.4    Bloomgarden, Z.T.5    Bush, M.A.6
  • 48
    • 84941243068 scopus 로고    scopus 로고
    • Impact of glucose-lowering drugs on cardiovascular disease in type 2 diabetes
    • Ferrannini E, DeFronzo RA. Impact of glucose-lowering drugs on cardiovascular disease in type 2 diabetes. Eur Heart J (2015) 36(34):2288-96. doi:10.1093/eurheartj/ehv239.
    • (2015) Eur Heart J , vol.36 , Issue.34 , pp. 2288-2296
    • Ferrannini, E.1    DeFronzo, R.A.2
  • 50
    • 84875179301 scopus 로고    scopus 로고
    • An inhibitor of the protein kinases TBK1 and IKK-e improves obesity-related metabolic dysfunctions in mice
    • Reilly SM, Chiang SH, Decker SJ, Chang L, Uhm M, Larsen MJ, et al. An inhibitor of the protein kinases TBK1 and IKK-e improves obesity-related metabolic dysfunctions in mice. Nat Med (2013) 19(3):313-21. doi:10.1038/nm.3082.
    • (2013) Nat Med , vol.19 , Issue.3 , pp. 313-321
    • Reilly, S.M.1    Chiang, S.H.2    Decker, S.J.3    Chang, L.4    Uhm, M.5    Larsen, M.J.6
  • 51
    • 84875443579 scopus 로고    scopus 로고
    • Obesity: teaching an old drug new tricks-amlexanox targets inflammation to improve metabolic dysfunction
    • Koch L. Obesity: teaching an old drug new tricks-amlexanox targets inflammation to improve metabolic dysfunction. Nat Rev Endocrinol (2013) 9(4):185. doi:10.1038/nrendo.2013.42.
    • (2013) Nat Rev Endocrinol , vol.9 , Issue.4 , pp. 185
    • Koch, L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.