A systematic review on the effect of acute aerobic exercise on arterial stiffness reveals a differential response in the upper and lower arterial segments

Hypertension Research

Volumn 40, Issue 2, 2017, Pages 146-172

  Mutter, Andrew F ^a   Cooke, Alexandra B ^a   Saleh, Olivier ^b   Gomez, Yessica Haydee ^b   Daskalopoulou, Stella S ^a,b  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

Author keywords

aerobic exercise; arterial stiffness; augmentation index; exercise testing; pulse wave velocity

Indexed keywords

ADULT; AEROBIC EXERCISE; ARTERIAL STIFFNESS; AUGMENTATION INDEX; DATA BASE; EXERCISE TEST; HUMAN; LOWER LIMB; MUSCLE FIBER CULTURE; PULSE WAVE; SYSTEMATIC REVIEW; AGED; BLOOD PRESSURE; EXERCISE; FEMALE; MALE; MIDDLE AGED; PHYSIOLOGY;

ADULT; AGED; BLOOD PRESSURE; EXERCISE; FEMALE; HUMANS; MALE; MIDDLE AGED; PULSE WAVE ANALYSIS; VASCULAR STIFFNESS;

EID: 85011705807     PISSN: 09169636     EISSN: 13484214     Source Type: Journal    
DOI: 10.1038/hr.2016.111     Document Type: Review

References (74)

1. WHO. Physical Inactivity: A Global Public Health Problem. World Health Organization: Geneva, Switzerland, 2012.
2. Francis K. Physical activity in the prevention of cardiovascular disease. Phys Ther 1996; 76: 456-468.
3. Laurent S, Cockcroft J, Van Bortel L, Boutouyrie P, Giannattasio C, Hayoz D, Pannier B, Vlachopoulos C, Wilkinson I, Struijker-Boudier H. Expert consensus document on arterial stiffness: methodological issues and clinical applications. Eur Heart J 2006; 27: 2588-2605.
4. Townsend RR, Wilkinson IB, Schiffrin EL, Avolio AP, Chirinos JA, Cockcroft JR, Heffernan KS, Lakatta EG, McEniery CM, Mitchell GF, Najjar SS, Nichols WW, Urbina EM, Weber T. Recommendations for improving and standardizing vascular research on arterial stiffness: a scientific statement from the American Heart Association. Hypertension 2015; 66: 698-722.
5. Laurent S, Boutouyrie P, Asmar R, Gautier I, Laloux B, Guize L, Ducimetiere P, Benetos A. Aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in hypertensive patients. Hypertension 2001; 37: 1236-1241.
6. Mancia G, De Backer G, Dominiczak A, Cifkova R, Fagard R, Germano G, Grassi G, Heagerty AM, Kjeldsen SE, Laurent S, Narkiewicz K, Ruilope L, Rynkiewicz A, Schmieder RE, Struijker Boudier HA, Zanchetti A, Vahanian A, Camm J, De Caterina R, Dean V, Dickstein K, Filippatos G, Funck-Brentano C, Hellemans I, Kristensen SD, McGregor K, Sechtem U, Silber S, Tendera M, Widimsky P, Zamorano JL, Erdine S, Kiowski W, Agabiti-Rosei E, Ambrosioni E, Lindholm LH, Manolis A, Nilsson PM, Redon J, Struijker-Boudier HA, Viigimaa M, Adamopoulos S, Bertomeu V, Clement D, Farsang C, Gaita D, Lip G, Mallion JM, Manolis AJ, O'Brien E, Ponikowski P, Ruschitzka F, Tamargo J, van Zwieten P, Waeber B, Williams B, The task force for the management of arterial hypertension of the European Society of H, The task force for the management of arterial hypertension of the European Society of C. 2007 Guidelines for the management of arterial hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Eur Heart J 2007; 28: 1462-1536.
7. Yambe T, Yoshizawa M, Saijo Y, Yamaguchi T, Shibata M, Konno S, Nitta S, Kuwayama T. Brachio-Ankle pulse wave velocity and cardio-Ankle vascular index (CAVI). Biomed Pharmacother 2004; 58 (Suppl 1): S95-S98.
8. Shirai K, Utino J, Otsuka K, Takata M. A novel blood pressure-independent arterial wall stiffness parameter; cardio-Ankle vascular index (CAVI). J Atheroscler Thromb 2006; 13: 101-107.
9. Bertovic DA, Waddell TK, Gatzka CD, Cameron JD, Dart AM, Kingwell BA. Muscular strength training is associated with low arterial compliance and high pulse pressure. Hypertension 1999; 33: 1385-1391.
10. Goldberg MJ, Boutcher SH, Boutcher YN. The effect of 4 weeks of aerobic exercise on vascular and baroreflex function of young men with a family history of hypertension. J Hum Hypertens 2012; 26: 644-649.
11. Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-Analyses: the PRISMA statement. Int J Surg 2010; 8: 336-341.
12. Egger MS, D, Altman EG. Systematic Reviews in Healthcare: Meta-Analysis in Context, 2nd edn. BMJ Publishing Group: London, UK, 2001.
13. Casey DP, Nichols WW, Braith RW. Impact of aging on central pressure wave reflection characteristics during exercise. Am J Hypertens 2008; 21: 419-424.
14. Dischl B, Engelberger RP, Gojanovic B, Liaudet L, Gremion G, Waeber B, Feihl F. Enhanced diastolic reflections on arterial pressure pulse during exercise recovery. Scand J Med Sci Sports 2011; 21: e325-e333.
15. Doonan RJ, Scheffler P, Yu A, Egiziano G, Mutter A, Bacon S, Carli F, Daskalopoulos ME, Daskalopoulou SS. Altered arterial stiffness and subendocardial viability ratio in young healthy light smokers after acute exercise. PLoS ONE 2011; 6: e26151.
16. Heffernan KS, Collier SR, Kelly EE, Jae SY, Fernhall B. Arterial stiffness and baroreflex sensitivity following bouts of aerobic and resistance exercise. Int J Sports Med 2007; 28: 197-203.
17. Kingwell BA, Berry KL, Cameron JD, Jennings GL, Dart AM. Arterial compliance increases after moderate-intensity cycling. Am J Physiol Heart Circ Physiol 1997; 273: H2186-H2191.
18. McClean CM, Clegg M, Shafat A, Murphy MH, Trinick T, Duly E, McLaughlin J, Fogarty M, Davison GW. The impact of acute moderate intensity exercise on arterial regional stiffness, lipid peroxidation, and antioxidant status in healthy males. Res Sports Med 2011; 19: 1-13.
19. Rakobowchuk M, Stuckey MI, Millar PJ, Gurr L, Macdonald MJ. Effect of acute sprint interval exercise on central and peripheral artery distensibility in young healthy males. Eur J Appl Physiol 2009; 105: 787-795.
20. Sharman JE, McEniery CM, Campbell RI, Coombes JS, Wilkinson IB, Cockcroft JR. The effect of exercise on large artery haemodynamics in healthy young men. Eur J Clin Invest 2005; 35: 738-744.
21. Sugawara J, Otsuki T, Tanabe T, Maeda S, Kuno S, Ajisaka R, Matsuda M. The effects of low-intensity single-leg exercise on regional arterial stiffness. Jpn J Physiol 2003; 53: 239-241.
22. Sugawara J, Maeda S, Otsuki T, Tanabe T, Ajisaka R, Matsuda M. Effects of nitric oxide synthase inhibitor on decrease in peripheral arterial stiffness with acute low-intensity aerobic exercise. Am J Physiol Heart Circ Physiol 2004; 287: H2666-H2669.
23. Tordi N, Mourot L, Colin E, Regnard J. Intermittent versus constant aerobic exercise: effects on arterial stiffness. Eur J Appl Physiol 2010; 108: 801-809.
24. Heffernan KS, Jae SY, Echols GH, Lepine NR, Fernhall B. Arterial stiffness and wave reflection following exercise in resistance-Trained men. Med Sci Sports Exerc 2007; 39: 842-848.
25. Ribeiro F, Oliveira NL, Pires J, Alves AJ, Oliveira J. Treadmill walking with load carriage increases aortic pressure wave reflection. Rev Port Cardiol 2014; 33: 425-430.
26. Wang H, Zhang T, Zhu W, Wu H, Yan S. Acute effects of continuous and interval low-intensity exercise on arterial stiffness in healthy young men. Eur J Appl Physiol 2014; 114: 1385-1392.
27. Zheng L, Zhang X, Zhu WL, Chen XH, Wu H, Yan SF. Acute effects of moderateintensity continuous and accumulated exercise on arterial stiffness in healthy young men. Eur J Appl Physiol 2015; 115: 177-185.
28. Attinà TM, Drummond ID, Malatino LS, Maxwell SR, Webb DJ. Phosphodiesterase type 5 inhibition improves arterial stiffness after exercise but not exercise capacity in hypertensive men. Am J Hypertens 2013; 26: 342-350.
29. Hanssen H, Nussbaumer M, Moor C, Cordes M, Schindler C, Schmidt-Trucksass A. Acute effects of interval versus continuous endurance training on pulse wave reflection in healthy young men. Atherosclerosis 2015; 238: 399-406.
30. Milatz F, Ketelhut S, Ketelhut RG. Favorable effect of aerobic exercise on arterial pressure and aortic pulse wave velocity during stress testing. Eur J Vasc Med 2015; 44: 271-276.
31. Zhou Z, He Z, Yuan M, Yin Z, Dang X, Zhu J, Zhu W. Longer rest intervals do not attenuate the superior effects of accumulated exercise on arterial stiffness. Eur J Appl Physiol 2015; 115: 2149-2157.
32. Liu HB, Yuan WX, Qin KR, Hou J. Acute effect of cycling intervention on carotid arterial hemodynamics: basketball athletes versus sedentary controls. Biomed Eng Online 2015; 14: S17.
33. Boutcher YN, Hopp JP, Boutcher SH. Acute effect of a single bout of aerobic exercise on vascular and baroreflex function of young males with a family history of hypertension. J Hum Hypertens 2011; 25: 311-319.
34. Campbell R, Fisher JP, Sharman JE, McDonnell BJ, Frenneaux MP. Contribution of nitric oxide to the blood pressure and arterial responses to exercise in humans. J Hum Hypertens 2011; 25: 262-270.
35. Chandrakumar D, Boutcher SH, Boutcher YN. Acute exercise effects on vascular and autonomic function in overweight men. J Sports Med Phys Fitness 2015; 55: 91-102.
36. Collier SR, Diggle MD, Heffernan KS, Kelly EE, Tobin MM, Fernhall B. Changes in arterial distensibility and flow-mediated dilation after acute resistance vs. aerobic exercise. J Strength Condit Res 2010; 24: 2846-2852.
37. Payne RA, Teh CH, Webb DJ, Maxwell SR. A generalized arterial transfer function derived at rest underestimates augmentation of central pressure after exercise. J Hypertens 2007; 25: 2266-2272.
38. Sharman JE, McEniery CM, Campbell R, Pusalkar P, Wilkinson IB, Coombes JS, Cockcroft JR. Nitric oxide does not significantly contribute to changes in pulse pressure amplification during light aerobic exercise. Hypertension 2008; 51: 856-861.
39. Akazawa N, Ra SG, Sugawara J, Maeda S. Influence of aerobic exercise training on post-exercise responses of aortic pulse pressure and augmentation pressure in postmenopausal women. Front Physiol 2015; 6: 268.
40. Lydakis C, Momen A, Blaha C, Gugoff S, Gray K, Herr M, Leuenberger UA, Sinoway LI. Changes of central haemodynamic parameters during mental stress and acute bouts of static and dynamic exercise. J Hum Hypertens 2008; 22: 320-328.
41. Naka KK, Tweddel AC, Parthimos D, Henderson A, Goodfellow J, Frenneaux MP. Arterial distensibility: acute changes following dynamic exercise in normal subjects. Am J Physiol Heart Circ Physiol 2003; 284: H970-H978.
42. Nickel KJ, Acree LS, Gardner AW. Effects of a single bout of exercise on arterial compliance in older adults. Angiology 2011; 62: 33-37.
43. Nottin S, Walther G, Vinet A, Dauzat M, Beck L, Messner-Pellenc P, Obert P. Reproducibility of automated pulse wave velocity measurement during exercise. Running head: pulse wave velocity during exercise. Archiv Malad Coeur Vaisseaux 2006; 99: 564-568.
44. Ranadive SM, Fahs CA, Yan H, Rossow LM, Agiovlasitis S, Fernhall B. Comparison of the acute impact of maximal arm and leg aerobic exercise on arterial stiffness. Eur J Appl Physiol 2011; 112: 2631-2635.
45. Doonan RJ, Mutter A, Egiziano G, Gomez YH, Daskalopoulou SS. Differences in arterial stiffness at rest and after acute exercise between young men and women. Hypertens Res 2013; 36: 226-231.
46. Hu M, Yan H, Ranadive SM, Agiovlasitis S, Fahs CA, Atiq M, Atique N, Fernhall B. Arterial stiffness response to exercise in persons with and without Down syndrome. Res Dev Disabil 2013; 34: 3139-3147.
47. Nieman D, Dew D, Krasen P. Gender difference in the acute influence of a 2-hour run on arterial stiffness in trained runners. Res Sports Med 2013; 21: 66-77.
48. Munir S, Jiang B, Guilcher A, Brett S, Redwood S, Marber M, Chowienczyk P. Exercise reduces arterial pressure augmentation through vasodilation of muscular arteries in humans. Am J Physiol Heart Circ Physiol 2008; 294: H1645-H1650.
49. Babcock MC, Lefferts WK, Hughes WE, Fitzgerald KL, Leyer BK, Redmond JG, Heffernan KS. Acute effect of high-intensity cycling exercise on carotid artery hemodynamic pulsatility. Eur J Appl Physiol 2015; 115: 1037-1045.
50. Burr JF, Boulter M, Beck K. Arterial stiffness results from eccentrically biased downhill running exercise. J Sci Med Sport 2015; 18: 230-235.
51. Gkaliagkousi E, Gavriilaki E, Nikolaidou B, Triantafyllou G, Douma S. Exercise-induced pulse wave velocity changes in untreated patients with essential hypertension: the effect of an angiotensin receptor antagonist. J Clin Hypertens 2014; 16: 482-487.
52. Lane AD, Ranadive SM, Yan H, Kappus RM, Cook MD, Sun P, Woods JA, Wilund K, Fernhall B. Effect of sex on wasted left ventricular effort following maximal exercise. Int J Sports Med 2013; 34: 770-776.
53. Yan H, Ranadive SM, Heffernan KS, Lane AD, Kappus RM, Cook MD, Wu PT, Sun P, Harvey IS, Woods JA, Wilund KR, Fernhall B. Hemodynamic and arterial stiffness differences between African-Americans and Caucasians after maximal exercise. Am J Physiol Heart Circ Physiol 2014; 306: H60-H68.
54. Hull JH, Ansley L, Bolton CE, Sharman JE, Knight RK, Cockcroft JR, Shale DJ, Garrod R. The effect of exercise on large artery haemodynamics in cystic fibrosis. J Cyst Fibros 2011; 10: 121-127.
55. Silver FH, Snowhill PB, Foran DJ. Mechanical behavior of vessel wall: a comparative study of aorta, vena cava, and carotid artery. Ann Biomed Eng 2003; 31: 793-803.
56. Sprangers RL, Wesseling KH, Imholz AL, Imholz BP, Wieling W. Initial blood pressure fall on stand up and exercise explained by changes in total peripheral resistance. J Appl Physiol 1991; 70: 523-530.
57. Belz GG. Elastic properties and Windkessel function of the human aorta. Cardiovasc Drugs Ther 1995; 9: 73-83.
58. Hamer M, Taylor A, Steptoe A. The effect of acute aerobic exercise on stress related blood pressure responses: a systematic review and meta-Analysis. Biol Psychol 2006; 71: 183-190.
59. Halliwill JR, Taylor JA, Eckberg DL. Impaired sympathetic vascular regulation in humans after acute dynamic exercise. J Physiol 1996; 495: 279-288.
60. Joyner MJ. Effect of exercise on arterial compliance. Circulation 2000; 102: 1214-1215.
61. Reed AS, Tschakovsky ME, Minson CT, Halliwill JR, Torp KD, Nauss LA, Joyner MJ. Skeletal muscle vasodilatation during sympathoexcitation is not neurally mediated in humans. J Physiol 2000; 525 (Part 1): 253-262.
62. Di Francescomarino S, Sciartilli A, Di Valerio V, Di Baldassarre A, Gallina S. The effect of physical exercise on endothelial function. Sports Med 2009; 39: 797-812.
63. Poveda JJ, Berrazueta JR, Ochoteco A, Montalban C, Garcia-Unzueta MT, Fernandez C, Pena N, Amado JA. Age-related responses of vasoactive factors during acute exercise. Horm Metab Res 1998; 30: 668-672.
64. Cooke AB, Toli E, Gomez YH, Mutter AF, Eisenberg MJ, Mantzoros CS, Daskalopoulou SS. From rest to stressed: endothelin-1 levels in young healthy smokers and non-smokers. Metabolism 2015; 64: 1103-1111.
65. Schmitt M, Qasem A, McEniery C, Wilkinson IB, Tatarinoff V, Noble K, Klemes J, Payne N, Frenneaux MP, Cockcroft J, Avolio A. Role of natriuretic peptides in regulation of conduit artery distensibility. Am J Physiol Heart Circ Physiol 2004; 287: H1167-H1171.
66. Willich SN, Lewis M, Lowel H, Arntz HR, Schubert F, Schroder R. Physical exertion as a trigger of acute myocardial infarction. Triggers and Mechanisms of Myocardial Infarction Study Group. N Engl J Med 1993; 329: 1684-1690.
67. Aizawa K, Mendelsohn ME, Overend TJ, Petrella RJ. Effect of upper body aerobic exercise on arterial stiffness in older adults. J Aging Phys Activity 2009; 17: 468-478.
68. McClean CM, McNeilly AM, Trinick TR, Murphy MH, Duly E, McLaughlin J, McEneny J, Burke G, Davison GW. Acute exercise and impaired glucose tolerance in obese humans. J Clin Lipidol 2009; 3: 262-268.
69. Sacre JW, Holland DJ, Jenkins C, Sharman JE. Augmentation index immediately after maximal exercise in patients with type 2 diabetes mellitus. Med Sci Sports Exerc 2012; 44: 75-83.
70. Seo J, Chung W, Kim S, Kim M, Zo J. Immediate impact of exercise on arterial stiffness in humans. World J Cardiovasc Dis 2013; 3: 40-45.
71. Shim CY, Hong GR, Park S, Yang WI, Choi D, Chung N, Ha JW. Impact of central haemodynamics on left ventricular function in individuals with an exaggerated blood pressure response to exercise. J Hypertens 2015; 33: 612-620; discussion 20.
72. Shim CY, Yang WI, Park S, Kang MK, Ko YG, Choi D, Jang Y, Chung N, Ha JW. Overweight and its association with aortic pressure wave reflection after exercise. Am J Hypertens 2011; 24: 1136-1142.
73. Tabara Y, Yuasa T, Oshiumi A, Kobayashi T, Miyawaki Y, Miki T, Kohara K. Effect of acute and long-Term aerobic exercise on arterial stiffness in the elderly. Hypertens Res 2007; 30: 895-902.
74. Tanaka S, Sugiura T, Yamashita S, Dohi Y, Kimura G, Ohte N. Differential response of central blood pressure to isometric and isotonic exercises. Scientific Rep 2014; 4: 5.