메뉴 건너뛰기




Volumn 47, Issue 4, 2017, Pages 189-202

The genome of the protozoan parasite Cystoisospora suis and a reverse vaccinology approach to identify vaccine candidates

Author keywords

Antigens; Apicomplexa; Coccidia; Illumina sequencing; Transcriptome; Vacceed

Indexed keywords

AMA1; M2AP; MEMBRANE PROTEIN; MIC1; MIC10; MIC12; MIC13; MIC2; MIC3; MIC4; MIC5; MIC8; PROTOZOAL VACCINE; ROP1; ROP13; ROP16; ROP2; ROP5; ROP8; ROP9; SAG1; SAG2; SAG3; SAG4; SAG5; SRS1; SRS2; SRS28; SRS9; UNCLASSIFIED DRUG; UNINDEXED DRUG; PARASITE ANTIGEN; PROTOZOAL DNA;

EID: 85011703163     PISSN: 00207519     EISSN: 18790135     Source Type: Journal    
DOI: 10.1016/j.ijpara.2016.11.007     Document Type: Article
Times cited : (28)

References (81)
  • 1
    • 79960959409 scopus 로고    scopus 로고
    • An observational study on the prevalence and impact of Isospora suis in suckling piglets in southwestern Ontario, and risk factors for shedding oocysts
    • Aliaga-Leyton, A., Webster, E., Friendship, R., Dewey, C., Vilaca, K., Peregrine, A.S., An observational study on the prevalence and impact of Isospora suis in suckling piglets in southwestern Ontario, and risk factors for shedding oocysts. Can. Vet. J. 52 (2011), 184–188.
    • (2011) Can. Vet. J. , vol.52 , pp. 184-188
    • Aliaga-Leyton, A.1    Webster, E.2    Friendship, R.3    Dewey, C.4    Vilaca, K.5    Peregrine, A.S.6
  • 2
    • 84872287798 scopus 로고    scopus 로고
    • Inferring hierarchical orthologous groups from orthologous gene pairs
    • Altenhoff, A.M., Gil, M., Gonnet, G.H., Dessimoz, C., Inferring hierarchical orthologous groups from orthologous gene pairs. PLoS One, 8, 2013, e53786.
    • (2013) PLoS One , vol.8 , pp. e53786
    • Altenhoff, A.M.1    Gil, M.2    Gonnet, G.H.3    Dessimoz, C.4
  • 3
    • 0038665562 scopus 로고    scopus 로고
    • Development of a vaccine for toxoplasmosis: current status
    • Bhopale, G.M., Development of a vaccine for toxoplasmosis: current status. Microbes Infect. 5 (2003), 457–462.
    • (2003) Microbes Infect. , vol.5 , pp. 457-462
    • Bhopale, G.M.1
  • 4
    • 84890982964 scopus 로고    scopus 로고
    • Securing poultry production from the ever-present Eimeria challenge
    • Blake, D.P., Tomley, F.M., Securing poultry production from the ever-present Eimeria challenge. Trends Parasitol. 30 (2014), 12–19.
    • (2014) Trends Parasitol. , vol.30 , pp. 12-19
    • Blake, D.P.1    Tomley, F.M.2
  • 6
    • 84988074679 scopus 로고
    • Improved silver staining of plant proteins, RNA and DNA in polyacrylamide gels
    • Blum, H.B.H., Gross, H.J., Improved silver staining of plant proteins, RNA and DNA in polyacrylamide gels. Electrophoresis 8 (1987), 93–99.
    • (1987) Electrophoresis , vol.8 , pp. 93-99
    • Blum, H.B.H.1    Gross, H.J.2
  • 7
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford, M.M., A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72 (1976), 248–254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 8
    • 0030585734 scopus 로고    scopus 로고
    • Evaluation of gene structure prediction programs
    • Burset, M., Guigo, R., Evaluation of gene structure prediction programs. Genomics 34 (1996), 353–367.
    • (1996) Genomics , vol.34 , pp. 353-367
    • Burset, M.1    Guigo, R.2
  • 10
    • 24644503098 scopus 로고    scopus 로고
    • Blast2GO: a universal tool for annotation, visualization and analysis in functional genomics research
    • Conesa, A., Gotz, S., Garcia-Gomez, J.M., Terol, J., Talon, M., Robles, M., Blast2GO: a universal tool for annotation, visualization and analysis in functional genomics research. Bioinformatics 21 (2005), 3674–3676.
    • (2005) Bioinformatics , vol.21 , pp. 3674-3676
    • Conesa, A.1    Gotz, S.2    Garcia-Gomez, J.M.3    Terol, J.4    Talon, M.5    Robles, M.6
  • 11
    • 84862797129 scopus 로고    scopus 로고
    • Toxoplasma gondii immune mapped protein-1 (TgIMP1) is a novel vaccine candidate against toxoplasmosis
    • Cui, X., Lei, T., Yang, D., Hao, P., Li, B., Liu, Q., Toxoplasma gondii immune mapped protein-1 (TgIMP1) is a novel vaccine candidate against toxoplasmosis. Vaccine 30 (2012), 2282–2287.
    • (2012) Vaccine , vol.30 , pp. 2282-2287
    • Cui, X.1    Lei, T.2    Yang, D.3    Hao, P.4    Li, B.5    Liu, Q.6
  • 13
    • 48749118637 scopus 로고    scopus 로고
    • Toxoplasma rhoptries: unique secretory organelles and source of promising vaccine proteins for immunoprevention of toxoplasmosis
    • Dlugonska, H., Toxoplasma rhoptries: unique secretory organelles and source of promising vaccine proteins for immunoprevention of toxoplasmosis. J. Biomed. Biotechnol., 2008, 2008, 632424.
    • (2008) J. Biomed. Biotechnol. , vol.2008 , pp. 632424
    • Dlugonska, H.1
  • 14
    • 12144269039 scopus 로고    scopus 로고
    • Sarcocystis neurona major surface antigen gene 1 (SAG1) shows evidence of having evolved under positive selection pressure
    • Elsheikha, H.M., Mansfield, L.S., Sarcocystis neurona major surface antigen gene 1 (SAG1) shows evidence of having evolved under positive selection pressure. Parasitol. Res. 94 (2004), 452–459.
    • (2004) Parasitol. Res. , vol.94 , pp. 452-459
    • Elsheikha, H.M.1    Mansfield, L.S.2
  • 15
    • 0034697980 scopus 로고    scopus 로고
    • Predicting subcellular localization of proteins based on their N-terminal amino acid sequence
    • Emanuelsson, O., Nielsen, H., Brunak, S., von Heijne, G., Predicting subcellular localization of proteins based on their N-terminal amino acid sequence. J. Mol. Biol. 300 (2000), 1005–1016.
    • (2000) J. Mol. Biol. , vol.300 , pp. 1005-1016
    • Emanuelsson, O.1    Nielsen, H.2    Brunak, S.3    von Heijne, G.4
  • 17
    • 84902519383 scopus 로고    scopus 로고
    • Immune response to Cystoisospora suis in piglets: local and systemic changes in T-cell subsets and selected mRNA transcripts in the small intestine
    • Gabner, S., Worliczek, H.L., Witter, K., Meyer, F.R., Gerner, W., Joachim, A., Immune response to Cystoisospora suis in piglets: local and systemic changes in T-cell subsets and selected mRNA transcripts in the small intestine. Parasite Immunol. 36 (2014), 277–291.
    • (2014) Parasite Immunol. , vol.36 , pp. 277-291
    • Gabner, S.1    Worliczek, H.L.2    Witter, K.3    Meyer, F.R.4    Gerner, W.5    Joachim, A.6
  • 19
    • 0032961627 scopus 로고    scopus 로고
    • Mass spectrometric identification of proteins from silver-stained polyacrylamide gel: a method for the removal of silver ions to enhance sensitivity
    • Gharahdaghi, F., Weinberg, C.R., Meagher, D.A., Imai, B.S., Mische, S.M., Mass spectrometric identification of proteins from silver-stained polyacrylamide gel: a method for the removal of silver ions to enhance sensitivity. Electrophoresis 20 (1999), 601–605.
    • (1999) Electrophoresis , vol.20 , pp. 601-605
    • Gharahdaghi, F.1    Weinberg, C.R.2    Meagher, D.A.3    Imai, B.S.4    Mische, S.M.5
  • 20
    • 84886737285 scopus 로고    scopus 로고
    • A novel strategy for classifying the output from an in silico vaccine discovery pipeline for eukaryotic pathogens using machine learning algorithms
    • Goodswen, S.J., Kennedy, P.J., Ellis, J.T., A novel strategy for classifying the output from an in silico vaccine discovery pipeline for eukaryotic pathogens using machine learning algorithms. BMC Bioinformatics, 14, 2013.
    • (2013) BMC Bioinformatics , vol.14
    • Goodswen, S.J.1    Kennedy, P.J.2    Ellis, J.T.3
  • 21
    • 84904725957 scopus 로고    scopus 로고
    • Discovering a vaccine against neosporosis using computers: is it feasible?
    • Goodswen, S.J., Kennedy, P.J., Ellis, J.T., Discovering a vaccine against neosporosis using computers: is it feasible?. Trends Parasitol. 30 (2014), 401–411.
    • (2014) Trends Parasitol. , vol.30 , pp. 401-411
    • Goodswen, S.J.1    Kennedy, P.J.2    Ellis, J.T.3
  • 22
    • 84920148723 scopus 로고    scopus 로고
    • Enhancing in silico protein-based vaccine discovery for eukaryotic pathogens using predicted peptide-MHC binding and peptide conservation scores
    • Goodswen, S.J., Kennedy, P.J., Ellis, J.T., Enhancing in silico protein-based vaccine discovery for eukaryotic pathogens using predicted peptide-MHC binding and peptide conservation scores. PLoS One, 9, 2014, e115745.
    • (2014) PLoS One , vol.9 , pp. e115745
    • Goodswen, S.J.1    Kennedy, P.J.2    Ellis, J.T.3
  • 23
    • 84904732727 scopus 로고    scopus 로고
    • Vacceed: a high-throughput in silico vaccine candidate discovery pipeline for eukaryotic pathogens based on reverse vaccinology
    • Goodswen, S.J., Kennedy, P.J., Ellis, J.T., Vacceed: a high-throughput in silico vaccine candidate discovery pipeline for eukaryotic pathogens based on reverse vaccinology. Bioinformatics 30 (2014), 2381–2383.
    • (2014) Bioinformatics , vol.30 , pp. 2381-2383
    • Goodswen, S.J.1    Kennedy, P.J.2    Ellis, J.T.3
  • 24
    • 84870880579 scopus 로고    scopus 로고
    • De novo reconstruction of the Toxoplasma gondii transcriptome improves on the current genome annotation and reveals alternatively spliced transcripts and putative long non-coding RNAs
    • Hassan, M.A., Melo, M.B., Haas, B., Jensen, K.D., Saeij, J.P., De novo reconstruction of the Toxoplasma gondii transcriptome improves on the current genome annotation and reveals alternatively spliced transcripts and putative long non-coding RNAs. BMC Genomics, 13, 2012, 696.
    • (2012) BMC Genomics , vol.13 , pp. 696
    • Hassan, M.A.1    Melo, M.B.2    Haas, B.3    Jensen, K.D.4    Saeij, J.P.5
  • 25
    • 84928675019 scopus 로고    scopus 로고
    • Asexual expansion of Toxoplasma gondii merozoites is distinct from tachyzoites and entails expression of non-overlapping gene families to attach, invade, and replicate within feline enterocytes
    • Hehl, A.B., Basso, W.U., Lippuner, C., Ramakrishnan, C., Okoniewski, M., Walker, R.A., Grigg, M.E., Smith, N.C., Deplazes, P., Asexual expansion of Toxoplasma gondii merozoites is distinct from tachyzoites and entails expression of non-overlapping gene families to attach, invade, and replicate within feline enterocytes. BMC Genomics, 16, 2015, 66.
    • (2015) BMC Genomics , vol.16 , pp. 66
    • Hehl, A.B.1    Basso, W.U.2    Lippuner, C.3    Ramakrishnan, C.4    Okoniewski, M.5    Walker, R.A.6    Grigg, M.E.7    Smith, N.C.8    Deplazes, P.9
  • 29
    • 0035935659 scopus 로고    scopus 로고
    • Advances and prospects for subunit vaccines against protozoa of veterinary importance
    • Jenkins, M.C., Advances and prospects for subunit vaccines against protozoa of veterinary importance. Vet. Parasitol. 101 (2001), 291–310.
    • (2001) Vet. Parasitol. , vol.101 , pp. 291-310
    • Jenkins, M.C.1
  • 30
    • 44949218553 scopus 로고    scopus 로고
    • In-gel digestion of proteins for MALDI-MS fingerprint mapping
    • J.E. Coligan B.M. Dunn H.L. Ploegh D.W. Speicher Wingfield John Wiley New York
    • Jimenez, C.R., Huang, L., Qiu, Y., Burlingame, A.L., In-gel digestion of proteins for MALDI-MS fingerprint mapping. Coligan, J.E., Dunn, B.M., Ploegh, H.L., Speicher, D.W., Wingfield, (eds.) Curr Protoc Protein Sci., 2001, John Wiley, New York, 16.14.1–16.14.5.
    • (2001) Curr Protoc Protein Sci. , pp. 16.14.1-16.14.5
    • Jimenez, C.R.1    Huang, L.2    Qiu, Y.3    Burlingame, A.L.4
  • 31
    • 83055188429 scopus 로고    scopus 로고
    • Efficacy of sulfonamides and Baycox((R)) against Isospora suis in experimental infections of suckling piglets
    • Joachim, A., Mundt, H.C., Efficacy of sulfonamides and Baycox((R)) against Isospora suis in experimental infections of suckling piglets. Parasitol. Res. 109 (2011), 1653–1659.
    • (2011) Parasitol. Res. , vol.109 , pp. 1653-1659
    • Joachim, A.1    Mundt, H.C.2
  • 34
    • 34547584314 scopus 로고    scopus 로고
    • Advantages of combined transmembrane topology and signal peptide prediction–the Phobius web server
    • Kall, L., Krogh, A., Sonnhammer, E.L., Advantages of combined transmembrane topology and signal peptide prediction–the Phobius web server. Nucleic Acids Res. 35 (2007), W429–W432.
    • (2007) Nucleic Acids Res. , vol.35 , pp. W429-W432
    • Kall, L.1    Krogh, A.2    Sonnhammer, E.L.3
  • 35
    • 84876996918 scopus 로고    scopus 로고
    • TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions
    • Kim, D., Pertea, G., Trapnell, C., Pimentel, H., Kelley, R., Salzberg, S.L., TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions. Genome Biol., 14, 2013, R36.
    • (2013) Genome Biol. , vol.14 , pp. R36
    • Kim, D.1    Pertea, G.2    Trapnell, C.3    Pimentel, H.4    Kelley, R.5    Salzberg, S.L.6
  • 36
    • 79960699711 scopus 로고    scopus 로고
    • Genome cartography: charting the apicomplexan genome
    • Kissinger, J.C., DeBarry, J., Genome cartography: charting the apicomplexan genome. Trends Parasitol. 27 (2011), 345–354.
    • (2011) Trends Parasitol. , vol.27 , pp. 345-354
    • Kissinger, J.C.1    DeBarry, J.2
  • 37
    • 2942544417 scopus 로고    scopus 로고
    • Gene finding in novel genomes
    • Korf, I., Gene finding in novel genomes. BMC Bioinformatics, 5, 2004, 59.
    • (2004) BMC Bioinformatics , vol.5 , pp. 59
    • Korf, I.1
  • 39
    • 33751104704 scopus 로고    scopus 로고
    • Improved method for predicting linear B-cell epitopes
    • Larsen, J.E., Lund, O., Nielsen, M., Improved method for predicting linear B-cell epitopes. Immunome Res., 2, 2006, 2.
    • (2006) Immunome Res. , vol.2 , pp. 2
    • Larsen, J.E.1    Lund, O.2    Nielsen, M.3
  • 40
    • 0034045751 scopus 로고    scopus 로고
    • Avian coccidiosis. A review of acquired intestinal immunity and vaccination strategies
    • Lillehoj, H.S., Lillehoj, E.P., Avian coccidiosis. A review of acquired intestinal immunity and vaccination strategies. Avian Dis. 44 (2000), 408–425.
    • (2000) Avian Dis. , vol.44 , pp. 408-425
    • Lillehoj, H.S.1    Lillehoj, E.P.2
  • 41
    • 84919708683 scopus 로고    scopus 로고
    • Recent advances in Toxoplasma gondii immunotherapeutics
    • Lim, S.S., Othman, R.Y., Recent advances in Toxoplasma gondii immunotherapeutics. Korean J. Parasitol. 52 (2014), 581–593.
    • (2014) Korean J. Parasitol. , vol.52 , pp. 581-593
    • Lim, S.S.1    Othman, R.Y.2
  • 42
    • 0006044829 scopus 로고
    • Enteric coccidial infections and coccidiosis in swine
    • Lindsay, D., Blagburn, B., Powe, T., Enteric coccidial infections and coccidiosis in swine. Compend. Cont. Educ. Pract. 14 (1992), 698–702.
    • (1992) Compend. Cont. Educ. Pract. , vol.14 , pp. 698-702
    • Lindsay, D.1    Blagburn, B.2    Powe, T.3
  • 43
    • 23044471766 scopus 로고    scopus 로고
    • An algorithm for progressive multiple alignment of sequences with insertions
    • Loytynoja, A., Goldman, N., An algorithm for progressive multiple alignment of sequences with insertions. Proc. Natl. Acad. Sci. U.S.A. 102 (2005), 10557–10562.
    • (2005) Proc. Natl. Acad. Sci. U.S.A. , vol.102 , pp. 10557-10562
    • Loytynoja, A.1    Goldman, N.2
  • 44
    • 42149175948 scopus 로고    scopus 로고
    • Whole-genome analysis reveals molecular innovations and evolutionary transitions in chromalveolate species
    • Martens, C., Vandepoele, K., Van de Peer, Y., Whole-genome analysis reveals molecular innovations and evolutionary transitions in chromalveolate species. Proc. Natl. Acad. Sci. U.S.A. 105 (2008), 3427–3432.
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 3427-3432
    • Martens, C.1    Vandepoele, K.2    Van de Peer, Y.3
  • 45
    • 77955847209 scopus 로고    scopus 로고
    • Non-coding RNA in apicomplexan parasites
    • Matrajt, M., Non-coding RNA in apicomplexan parasites. Mol. Biochem. Parasitol. 174 (2010), 1–7.
    • (2010) Mol. Biochem. Parasitol. , vol.174 , pp. 1-7
    • Matrajt, M.1
  • 46
    • 84904736092 scopus 로고    scopus 로고
    • Successful vaccines for naturally occurring protozoal diseases of animals should guide human vaccine research. A review of protozoal vaccines and their designs
    • McAllister, M.M., Successful vaccines for naturally occurring protozoal diseases of animals should guide human vaccine research. A review of protozoal vaccines and their designs. Parasitology 141 (2014), 624–640.
    • (2014) Parasitology , vol.141 , pp. 624-640
    • McAllister, M.M.1
  • 47
    • 0032906581 scopus 로고    scopus 로고
    • Occurrence of Isospora suis in larger piglet production units and on specialized piglet rearing farms
    • Meyer, C., Joachim, A., Daugschies, A., Occurrence of Isospora suis in larger piglet production units and on specialized piglet rearing farms. Vet. Parasitol. 82 (1999), 277–284.
    • (1999) Vet. Parasitol. , vol.82 , pp. 277-284
    • Meyer, C.1    Joachim, A.2    Daugschies, A.3
  • 48
    • 23144455729 scopus 로고    scopus 로고
    • OrfPredictor: predicting protein-coding regions in EST-derived sequences
    • Min, X.J., Butler, G., Storms, R., Tsang, A., OrfPredictor: predicting protein-coding regions in EST-derived sequences. Nucleic Acids Res. 33 (2005), W677–W680.
    • (2005) Nucleic Acids Res. , vol.33 , pp. W677-W680
    • Min, X.J.1    Butler, G.2    Storms, R.3    Tsang, A.4
  • 49
    • 84899123083 scopus 로고    scopus 로고
    • Vaccines against neosporosis: what can we learn from the past studies?
    • Monney, T., Hemphill, A., Vaccines against neosporosis: what can we learn from the past studies?. Exp. Parasitol. 140 (2014), 52–70.
    • (2014) Exp. Parasitol. , vol.140 , pp. 52-70
    • Monney, T.1    Hemphill, A.2
  • 50
    • 84861657429 scopus 로고    scopus 로고
    • Vaccines against a major cause of abortion in cattle, Neospora caninum infection
    • Monney, T., Debache, K., Hemphill, A., Vaccines against a major cause of abortion in cattle, Neospora caninum infection. Animals (Basel) 1 (2011), 306–325.
    • (2011) Animals (Basel) , vol.1 , pp. 306-325
    • Monney, T.1    Debache, K.2    Hemphill, A.3
  • 53
    • 33747860914 scopus 로고    scopus 로고
    • Additional gene ontology structure for improved biological reasoning
    • Myhre, S., Tveit, H., Mollestad, T., Laegreid, A., Additional gene ontology structure for improved biological reasoning. Bioinformatics 22 (2006), 2020–2027.
    • (2006) Bioinformatics , vol.22 , pp. 2020-2027
    • Myhre, S.1    Tveit, H.2    Mollestad, T.3    Laegreid, A.4
  • 54
    • 73349096884 scopus 로고    scopus 로고
    • GRA proteins of Toxoplasma gondii: maintenance of host-parasite interactions across the parasitophorous vacuolar membrane
    • Nam, H.W., GRA proteins of Toxoplasma gondii: maintenance of host-parasite interactions across the parasitophorous vacuolar membrane. Korean J. Parasitol. 47:Suppl (2009), S29–S37.
    • (2009) Korean J. Parasitol. , vol.47 , pp. S29-S37
    • Nam, H.W.1
  • 55
    • 0036362368 scopus 로고    scopus 로고
    • Vaccine development against Neospora caninum infection
    • Nishikawa, Y., Mikami, T., Nagasawa, H., Vaccine development against Neospora caninum infection. J. Vet. Med. Sci. 64 (2002), 1–5.
    • (2002) J. Vet. Med. Sci. , vol.64 , pp. 1-5
    • Nishikawa, Y.1    Mikami, T.2    Nagasawa, H.3
  • 56
    • 84942295733 scopus 로고    scopus 로고
    • Molecular phylogenetics of eimeriid coccidia (Eimeriidae, Eimeriorina, Apicomplexa, Alveolata): a preliminary multi-gene and multi-genome approach
    • Ogedengbe, J.D., Ogedengbe, M.E., Hafeez, M.A., Barta, J.R., Molecular phylogenetics of eimeriid coccidia (Eimeriidae, Eimeriorina, Apicomplexa, Alveolata): a preliminary multi-gene and multi-genome approach. Parasitol. Res. 114 (2015), 4149–4160.
    • (2015) Parasitol. Res. , vol.114 , pp. 4149-4160
    • Ogedengbe, J.D.1    Ogedengbe, M.E.2    Hafeez, M.A.3    Barta, J.R.4
  • 57
    • 34249848751 scopus 로고    scopus 로고
    • CEGMA: a pipeline to accurately annotate core genes in eukaryotic genomes
    • Parra, G., Bradnam, K., Korf, I., CEGMA: a pipeline to accurately annotate core genes in eukaryotic genomes. Bioinformatics 23 (2007), 1061–1067.
    • (2007) Bioinformatics , vol.23 , pp. 1061-1067
    • Parra, G.1    Bradnam, K.2    Korf, I.3
  • 58
    • 80053345905 scopus 로고    scopus 로고
    • SignalP 4.0: discriminating signal peptides from transmembrane regions
    • Petersen, T.N., Brunak, S., von Heijne, G., Nielsen, H., SignalP 4.0: discriminating signal peptides from transmembrane regions. Nat. Methods 8 (2011), 785–786.
    • (2011) Nat. Methods , vol.8 , pp. 785-786
    • Petersen, T.N.1    Brunak, S.2    von Heijne, G.3    Nielsen, H.4
  • 60
    • 84929483930 scopus 로고    scopus 로고
    • Comprehensive evaluation of Toxoplasma gondii VEG and Neospora caninum LIV genomes with tachyzoite stage transcriptome and proteome defines novel transcript features
    • Ramaprasad, A., Mourier, T., Naeem, R., Malas, T.B., Moussa, E., Panigrahi, A., Vermont, S.J., Otto, T.D., Wastling, J., Pain, A., Comprehensive evaluation of Toxoplasma gondii VEG and Neospora caninum LIV genomes with tachyzoite stage transcriptome and proteome defines novel transcript features. PLoS One, 10, 2015, e0124473.
    • (2015) PLoS One , vol.10 , pp. e0124473
    • Ramaprasad, A.1    Mourier, T.2    Naeem, R.3    Malas, T.B.4    Moussa, E.5    Panigrahi, A.6    Vermont, S.J.7    Otto, T.D.8    Wastling, J.9    Pain, A.10
  • 61
    • 67650499884 scopus 로고    scopus 로고
    • Neospora caninum–how close are we to development of an efficacious vaccine that prevents abortion in cattle?
    • Reichel, M.P., Ellis, J.T., Neospora caninum–how close are we to development of an efficacious vaccine that prevents abortion in cattle?. Int. J. Parasitol. 39 (2009), 1173–1187.
    • (2009) Int. J. Parasitol. , vol.39 , pp. 1173-1187
    • Reichel, M.P.1    Ellis, J.T.2
  • 62
    • 40649119254 scopus 로고    scopus 로고
    • Phylogenetic analysis of Cystoisospora species at the rRNA ITS1 locus and development of a PCR-RFLP assay
    • Samarasinghe, B., Johnson, J., Ryan, U., Phylogenetic analysis of Cystoisospora species at the rRNA ITS1 locus and development of a PCR-RFLP assay. Exp. Parasitol. 118 (2008), 592–595.
    • (2008) Exp. Parasitol. , vol.118 , pp. 592-595
    • Samarasinghe, B.1    Johnson, J.2    Ryan, U.3
  • 63
    • 79953678075 scopus 로고    scopus 로고
    • The apicomplexan plastid and its evolution
    • Sato, S., The apicomplexan plastid and its evolution. Cell. Mol. Life Sci. 68 (2011), 1285–1296.
    • (2011) Cell. Mol. Life Sci. , vol.68 , pp. 1285-1296
    • Sato, S.1
  • 64
    • 84859768479 scopus 로고    scopus 로고
    • Oases: robust de novo RNA-seq assembly across the dynamic range of expression levels
    • Schulz, M.H., Zerbino, D.R., Vingron, M., Birney, E., Oases: robust de novo RNA-seq assembly across the dynamic range of expression levels. Bioinformatics 28 (2012), 1086–1092.
    • (2012) Bioinformatics , vol.28 , pp. 1086-1092
    • Schulz, M.H.1    Zerbino, D.R.2    Vingron, M.3    Birney, E.4
  • 65
    • 84884988364 scopus 로고    scopus 로고
    • Transfer of Cystoisospora suis-specific colostral antibodies and their correlation with the course of neonatal porcine cystoisosporosis
    • Schwarz, L., Joachim, A., Worliczek, H.L., Transfer of Cystoisospora suis-specific colostral antibodies and their correlation with the course of neonatal porcine cystoisosporosis. Vet. Parasitol. 197 (2013), 487–497.
    • (2013) Vet. Parasitol. , vol.197 , pp. 487-497
    • Schwarz, L.1    Joachim, A.2    Worliczek, H.L.3
  • 66
    • 84901182620 scopus 로고    scopus 로고
    • Superinfection of sows with Cystoisospora suis ante partum leads to a milder course of cystoisosporosis in suckling piglets
    • Schwarz, L., Worliczek, H.L., Winkler, M., Joachim, A., Superinfection of sows with Cystoisospora suis ante partum leads to a milder course of cystoisosporosis in suckling piglets. Vet. Parasitol. 204 (2014), 158–168.
    • (2014) Vet. Parasitol. , vol.204 , pp. 158-168
    • Schwarz, L.1    Worliczek, H.L.2    Winkler, M.3    Joachim, A.4
  • 67
    • 0029927505 scopus 로고    scopus 로고
    • Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels
    • Shevchenko, A., Wilm, M., Vorm, O., Mann, M., Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal. Chem. 68 (1996), 850–858.
    • (1996) Anal. Chem. , vol.68 , pp. 850-858
    • Shevchenko, A.1    Wilm, M.2    Vorm, O.3    Mann, M.4
  • 70
    • 84888135119 scopus 로고    scopus 로고
    • Escaping the immune system: how the malaria parasite makes vaccine development a challenge
    • Stanisic, D.I., Barry, A.E., Good, M.F., Escaping the immune system: how the malaria parasite makes vaccine development a challenge. Trends Parasitol. 29 (2013), 612–622.
    • (2013) Trends Parasitol. , vol.29 , pp. 612-622
    • Stanisic, D.I.1    Barry, A.E.2    Good, M.F.3
  • 72
    • 0030969267 scopus 로고    scopus 로고
    • Studies of resistance to anticoccidials in Eimeria field isolates and pure Eimeria strains
    • Stephen, B., Rommel, M., Daugschies, A., Haberkorn, A., Studies of resistance to anticoccidials in Eimeria field isolates and pure Eimeria strains. Vet. Parasitol. 69 (1997), 19–29.
    • (1997) Vet. Parasitol. , vol.69 , pp. 19-29
    • Stephen, B.1    Rommel, M.2    Daugschies, A.3    Haberkorn, A.4
  • 74
    • 84875634162 scopus 로고    scopus 로고
    • Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration
    • Thorvaldsdottir, H., Robinson, J.T., Mesirov, J.P., Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration. Brief Bioinform. 14 (2013), 178–192.
    • (2013) Brief Bioinform. , vol.14 , pp. 178-192
    • Thorvaldsdottir, H.1    Robinson, J.T.2    Mesirov, J.P.3
  • 76
    • 33645093214 scopus 로고    scopus 로고
    • Protecting babies: vaccine strategies to prevent foetopathy in Neospora caninum-infected cattle
    • Williams, D.J., Trees, A.J., Protecting babies: vaccine strategies to prevent foetopathy in Neospora caninum-infected cattle. Parasite Immunol. 28 (2006), 61–67.
    • (2006) Parasite Immunol. , vol.28 , pp. 61-67
    • Williams, D.J.1    Trees, A.J.2
  • 78
    • 77957316544 scopus 로고    scopus 로고
    • Faeces, FACS, and functional assays–preparation of Isospora suis oocyst antigen and representative controls for immunoassays
    • Worliczek, H.L., Ruttkowski, B., Joachim, A., Saalmuller, A., Gerner, W., Faeces, FACS, and functional assays–preparation of Isospora suis oocyst antigen and representative controls for immunoassays. Parasitology 137 (2010), 1637–1643.
    • (2010) Parasitology , vol.137 , pp. 1637-1643
    • Worliczek, H.L.1    Ruttkowski, B.2    Joachim, A.3    Saalmuller, A.4    Gerner, W.5
  • 79
    • 84879819354 scopus 로고    scopus 로고
    • Isospora suis in an epithelial cell culture system - an in vitro model for sexual development in coccidia
    • Worliczek, H.L., Ruttkowski, B., Schwarz, L., Witter, K., Tschulenk, W., Joachim, A., Isospora suis in an epithelial cell culture system - an in vitro model for sexual development in coccidia. PLoS One, 8, 2013, e69797.
    • (2013) PLoS One , vol.8 , pp. e69797
    • Worliczek, H.L.1    Ruttkowski, B.2    Schwarz, L.3    Witter, K.4    Tschulenk, W.5    Joachim, A.6
  • 81
    • 0033965297 scopus 로고    scopus 로고
    • Cryptosporidium parvum appears to lack a plastid genome
    • Zhu, G., Marchewka, M.J., Keithly, J.S., Cryptosporidium parvum appears to lack a plastid genome. Microbiology 146:Pt 2 (2000), 315–321.
    • (2000) Microbiology , vol.146 , pp. 315-321
    • Zhu, G.1    Marchewka, M.J.2    Keithly, J.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.