-
1
-
-
84895827127
-
T-cell trafficking and anti-adhesion strategies in inflammatory bowel disease: Current and future prospects
-
Mosli MH, Rivera-Nieves J, Feagan BG: T-cell trafficking and anti-adhesion strategies in inflammatory bowel disease: current and future prospects. Drugs 2014; 74: 297-311.
-
(2014)
Drugs
, vol.74
, pp. 297-311
-
-
Mosli, M.H.1
Rivera-Nieves, J.2
Feagan, B.G.3
-
2
-
-
0037413468
-
Natalizumab for active Crohn's disease
-
Ghosh S, Goldin E, Gordon FH, Malchow HA, Rask-Madsen J, Rutgeerts P, Vyhnalek P, Zadorova Z, Palmer T, Donoghue S; Natalizumab Pan-European Study Group: Natalizumab for active Crohn's disease. N Engl J Med 2003; 348: 24-32.
-
(2003)
N Engl J Med
, vol.348
, pp. 24-32
-
-
Ghosh, S.1
Goldin, E.2
Gordon, F.H.3
Malchow, H.A.4
Rask-Madsen, J.5
Rutgeerts, P.6
Vyhnalek, P.7
Zadorova, Z.8
Palmer, T.9
Donoghue, S.10
-
3
-
-
27644441529
-
Natalizumab induction and maintenance therapy for Crohn's disease
-
Sandborn WJ, Colombel JF, Enns R, Feagan BG, Hanauer SB, Lawrance IC, Panaccione R, Sanders M, Schreiber S, Targan S, van Deventer S, Goldblum R, Despain D, Hogge GS, Rutgeerts P; International Efficacy of Natalizumab as Active Crohn's Therapy (ENACT-1) Trial Group; Evaluation of Natalizumab as Continuous Therapy (ENACT-2) Trial Group: Natalizumab induction and maintenance therapy for Crohn's disease. N Engl J Med 2005; 353: 1912-1925.
-
(2005)
N Engl J Med
, vol.353
, pp. 1912-1925
-
-
Sandborn, W.J.1
Colombel, J.F.2
Enns, R.3
Feagan, B.G.4
Hanauer, S.B.5
Lawrance, I.C.6
Panaccione, R.7
Sanders, M.8
Schreiber, S.9
Targan, S.10
Van Deventer, S.11
Goldblum, R.12
Despain, D.13
Hogge, G.S.14
Rutgeerts, P.15
-
4
-
-
34247884424
-
Natalizumab for the treatment of active Crohn's disease: Results of the ENCORE trial
-
Targan SR, Feagan BG, Fedorak RN, Lashner BA, Panaccione R, Present DH, Spehlmann ME, Rutgeerts PJ, Tulassay Z, Volfova M, Wolf DC, Hernandez C, Bornstein J, Sandborn WJ; International Efficacy of Natalizumab in Crohn's Disease Response and Remission (ENCORE) Trial Group: Natalizumab for the treatment of active Crohn's disease: results of the ENCORE trial. Gastroenterology 2007; 132: 1672-1683.
-
(2007)
Gastroenterology
, vol.132
, pp. 1672-1683
-
-
Targan, S.R.1
Feagan, B.G.2
Fedorak, R.N.3
Lashner, B.A.4
Panaccione, R.5
Present, D.H.6
Spehlmann, M.E.7
Rutgeerts, P.J.8
Tulassay, Z.9
Volfova, M.10
Wolf, D.C.11
Hernandez, C.12
Bornstein, J.13
Sandborn, W.J.14
-
5
-
-
84952916148
-
Safety and efficacy of AJM300, an oral antagonist of α4 integrin, in induction therapy for patients with active ulcerative colitis
-
e2
-
Yoshimura N, Watanabe M, Motoya S, Tominaga K, Matsuoka K, Iwakiri R, Watanabe K, Hibi T; AJM300 Study Group: Safety and efficacy of AJM300, an oral antagonist of α4 integrin, in induction therapy for patients with active ulcerative colitis. Gastroenterology 2015; 149: 1775-1783.e2.
-
(2015)
Gastroenterology
, vol.149
, pp. 1775-1783
-
-
Yoshimura, N.1
Watanabe, M.2
Motoya, S.3
Tominaga, K.4
Matsuoka, K.5
Iwakiri, R.6
Watanabe, K.7
Hibi, T.8
-
6
-
-
84882769357
-
Vedolizumab as induction and maintenance therapy for ulcerative colitis
-
Feagan BG, Rutgeerts P, Sands BE, Hanauer S, Colombel JF, Sandborn WJ, Van Assche G, Axler J, Kim HJ, Danese S, Fox I, Milch C, Sankoh S, Wyant T, Xu J, Parikh A; GEMINI 1 Study Group: Vedolizumab as induction and maintenance therapy for ulcerative colitis. N Engl J Med 2013; 369: 699-710.
-
(2013)
N Engl J Med
, vol.369
, pp. 699-710
-
-
Feagan, B.G.1
Rutgeerts, P.2
Sands, B.E.3
Hanauer, S.4
Colombel, J.F.5
Sandborn, W.J.6
Van Assche, G.7
Axler, J.8
Kim, H.J.9
Danese, S.10
Fox, I.11
Milch, C.12
Sankoh, S.13
Wyant, T.14
Xu, J.15
Parikh, A.16
-
7
-
-
84882749768
-
Vedolizumab as induction and maintenance therapy for Crohn's disease
-
Sandborn WJ, Feagan BG, Rutgeerts P, Hanauer S, Colombel JF, Sands BE, Lukas M, Fedorak RN, Lee S, Bressler B, Fox I, Rosario M, Sankoh S, Xu J, Stephens K, Milch C, Parikh A; GEMINI 2 Study Group: Vedolizumab as induction and maintenance therapy for Crohn's disease. N Engl J Med 2013; 369: 711-721.
-
(2013)
N Engl J Med
, vol.369
, pp. 711-721
-
-
Sandborn, W.J.1
Feagan, B.G.2
Rutgeerts, P.3
Hanauer, S.4
Colombel, J.F.5
Sands, B.E.6
Lukas, M.7
Fedorak, R.N.8
Lee, S.9
Bressler, B.10
Fox, I.11
Rosario, M.12
Sankoh, S.13
Xu, J.14
Stephens, K.15
Milch, C.16
Parikh, A.17
-
8
-
-
84904857048
-
Etrolizumab as induction therapy for ulcerative colitis: A randomised, controlled, phase 2 trial
-
Vermeire S, O'Byrne S, Keir M, Williams M, Lu TT, Mansfield JC, Lamb CA, Feagan BG, Panes J, Salas A, Baumgart DC, Schreiber S, Dotan I, Sandborn WJ, Tew GW, Luca D, Tang MT, Diehl L, Eastham-Anderson J, De Hertogh G, Perrier C, Egen JG, Kirby JA, van Assche G, Rutgeerts P: Etrolizumab as induction therapy for ulcerative colitis: a randomised, controlled, phase 2 trial. Lancet 2014; 384: 309-318.
-
(2014)
Lancet
, vol.384
, pp. 309-318
-
-
Vermeire, S.1
O'Byrne, S.2
Keir, M.3
Williams, M.4
Lu, T.T.5
Mansfield, J.C.6
Lamb, C.A.7
Feagan, B.G.8
Panes, J.9
Salas, A.10
Baumgart, D.C.11
Schreiber, S.12
Dotan, I.13
Sandborn, W.J.14
Tew, G.W.15
Luca, D.16
Tang, M.T.17
Diehl, L.18
Eastham-Anderson, J.19
De Hertogh, G.20
Perrier, C.21
Egen, J.G.22
Kirby, J.A.23
Van Assche, G.24
Rutgeerts, P.25
more..
-
9
-
-
79960336916
-
The mucosal addressin cell adhesion molecule antibody PF-00547,659 in ulcerative colitis: A randomised study
-
Vermeire S, Ghosh S, Panes J, Dahlerup JF, Luegering A, Sirotiakova J, Strauch U, Burgess G, Spanton J, Martin SW, Niezychowski W: The mucosal addressin cell adhesion molecule antibody PF-00547,659 in ulcerative colitis: a randomised study. Gut 2011; 60: 1068-1075.
-
(2011)
Gut
, vol.60
, pp. 1068-1075
-
-
Vermeire, S.1
Ghosh, S.2
Panes, J.3
Dahlerup, J.F.4
Luegering, A.5
Sirotiakova, J.6
Strauch, U.7
Burgess, G.8
Spanton, J.9
Martin, S.W.10
Niezychowski, W.11
-
10
-
-
85009704942
-
Anti-MAdCAM-1 antibody (PF-00547659) for active refractory Crohn's disease: Results of the OPERA study
-
Sandborn W, Lee SD, Tarabar D, Louis E, Klopocka M, Klaus J, Reinisch W, Hebuterne X, Il Park D, Schreiber S, Gorelick KJ, Hassan-Zahraee M, Brown LS, Ahmad A, Cheng JB, Cataldi F, D'Haens GR: Anti-MAdCAM-1 antibody (PF-00547659) for active refractory Crohn's disease: results of the OPERA study. Gastroenterology 2015; 148:S162.
-
(2015)
Gastroenterology
, vol.148
, pp. S162
-
-
Sandborn, W.1
Lee, S.D.2
Tarabar, D.3
Louis, E.4
Klopocka, M.5
Klaus, J.6
Reinisch, W.7
Hebuterne, X.8
Il Park, D.9
Schreiber, S.10
Gorelick, K.J.11
Hassan-Zahraee, M.12
Brown, L.S.13
Ahmad, A.14
Cheng, J.B.15
Cataldi, F.16
D'Haens, G.R.17
-
11
-
-
84944887463
-
TURANDOT: A randomized, multicenter double-blind, placebo-controlled study of the safety and efficacy of anti-MAdCAM antibody PF-00547659 (PF) in patients with moderate to severe ulcerative colitis (UC)
-
Vermeire S, Sandborn W, Danese S, Hebuterne X, Salzberg B, Klopocka M, Tarabar D, Vanasek T, Gregus M, Hellstern P, Kim JS, Sparrow M, Gorelick KJ, Ahmad A, Hassan-Zahraee M, Pradhan V, Cataldi F, Reinisch W: TURANDOT: a randomized, multicenter double-blind, placebo-controlled study of the safety and efficacy of anti-MAdCAM antibody PF-00547659 (PF) in patients with moderate to severe ulcerative colitis (UC). J Crohns Colitis 2015; 9:S13-S14.
-
(2015)
J Crohns Colitis
, vol.9
, pp. S13-S14
-
-
Vermeire, S.1
Sandborn, W.2
Danese, S.3
Hebuterne, X.4
Salzberg, B.5
Klopocka, M.6
Tarabar, D.7
Vanasek, T.8
Gregus, M.9
Hellstern, P.10
Kim, J.S.11
Sparrow, M.12
Gorelick, K.J.13
Ahmad, A.14
Hassan-Zahraee, M.15
Pradhan, V.16
Cataldi, F.17
Reinisch, W.18
-
12
-
-
84875195096
-
A randomized controlled trial of the efficacy and safety of CCX282-B, an orally-administered blocker of chemokine receptor CCR9, for patients with Crohn's disease
-
Keshav S, Vanasek T, Niv Y, Petryka R, Howaldt S, Bafutto M, Racz I, Hetzel D, Nielsen OH, Vermeire S, Reinisch W, Karlen P, Schreiber S, Schall TJ, Bekker P; A randomized controlled trial of the efficacy and safety of CCX282-B, an orally-administered blocker of chemokine receptor CCR9, for patients with Crohn's disease. PLoS One 2013; 8:e60094.
-
(2013)
PLoS One
, vol.8
-
-
Keshav, S.1
Vanasek, T.2
Niv, Y.3
Petryka, R.4
Howaldt, S.5
Bafutto, M.6
Racz, I.7
Hetzel, D.8
Nielsen, O.H.9
Vermeire, S.10
Reinisch, W.11
Karlen, P.12
Schreiber, S.13
Schall, T.J.14
Bekker, P.15
-
13
-
-
0036288638
-
ISIS 2302-CS9 Investigators: Double blind, placebo controlled trial of the remission inducing and steroid sparing properties of an ICAM-1 antisense oligodeoxynucleotide, alicaforsen (ISIS 2302), in active steroid dependent Crohn's disease
-
Yacyshyn BR, Chey WY, Goff J, Salzberg B, Baerg R, Buchman AL, Tami J, Yu R, Gibiansky E, Shanahan WR; ISIS 2302-CS9 Investigators: Double blind, placebo controlled trial of the remission inducing and steroid sparing properties of an ICAM-1 antisense oligodeoxynucleotide, alicaforsen (ISIS 2302), in active steroid dependent Crohn's disease. Gut 2002; 51: 30-36.
-
(2002)
Gut
, vol.51
, pp. 30-36
-
-
Yacyshyn, B.R.1
Chey, W.Y.2
Goff, J.3
Salzberg, B.4
Baerg, R.5
Buchman, A.L.6
Tami, J.7
Yu, R.8
Gibiansky, E.9
Shanahan, W.R.10
-
14
-
-
0037413467
-
A controlled trial of natalizumab for relapsing multiple sclerosis
-
Miller DH, Khan OA, Sheremata WA, Blumhardt LD, Rice GP, Libonati MA, Willmer-Hulme AJ, Dalton CM, Miszkiel KA, O'Connor PW; International Natalizumab Multiple Sclerosis Trial Group: A controlled trial of natalizumab for relapsing multiple sclerosis. N Engl J Med 2003; 348: 15-23.
-
(2003)
N Engl J Med
, vol.348
, pp. 15-23
-
-
Miller, D.H.1
Khan, O.A.2
Sheremata, W.A.3
Blumhardt, L.D.4
Rice, G.P.5
Libonati, M.A.6
Willmer-Hulme, A.J.7
Dalton, C.M.8
Miszkiel, K.A.9
O'Connor, P.W.10
-
15
-
-
33644584352
-
A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis
-
Polman CH, O'Connor PW, Havrdova E, Hutchinson M, Kappos L, Miller DH, Phillips JT, Lublin FD, Giovannoni G, Wajgt A, Toal M, Lynn F, Panzara MA, Sandrock AW; AFFIRM Investigators: A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis. N Engl J Med 2006; 354: 899-910.
-
(2006)
N Engl J Med
, vol.354
, pp. 899-910
-
-
Polman, C.H.1
O'Connor, P.W.2
Havrdova, E.3
Hutchinson, M.4
Kappos, L.5
Miller, D.H.6
Phillips, J.T.7
Lublin, F.D.8
Giovannoni, G.9
Wajgt, A.10
Toal, M.11
Lynn, F.12
Panzara, M.A.13
Sandrock, A.W.14
-
16
-
-
0027248939
-
Attenuation of colitis in the cotton-top tamarin by anti-alpha 4 integrin monoclonal antibody
-
Podolsky DK, Lobb R, King N, Benjamin CD, Pepinsky B, Sehgal P, deBeaumont M: Attenuation of colitis in the cotton-top tamarin by anti-alpha 4 integrin monoclonal antibody. J Clin Invest 1993; 92: 372-380.
-
(1993)
J Clin Invest
, vol.92
, pp. 372-380
-
-
Podolsky, D.K.1
Lobb, R.2
King, N.3
Benjamin, C.D.4
Pepinsky, B.5
Sehgal, P.6
DeBeaumont, M.7
-
17
-
-
22844445587
-
Progressive multifocal leukoencephalopathy after natalizumab therapy for Crohn's disease
-
Van Assche G, Van Ranst M, Sciot R, Dubois B, Vermeire S, Noman M, Verbeeck J, Geboes K, Robberecht W, Rutgeerts P: Progressive multifocal leukoencephalopathy after natalizumab therapy for Crohn's disease. N Engl J Med 2005; 353: 362-368.
-
(2005)
N Engl J Med
, vol.353
, pp. 362-368
-
-
Van Assche, G.1
Van Ranst, M.2
Sciot, R.3
Dubois, B.4
Vermeire, S.5
Noman, M.6
Verbeeck, J.7
Geboes, K.8
Robberecht, W.9
Rutgeerts, P.10
-
18
-
-
84863607194
-
Anti-JC virus antibodies in a large German natalizumab-treated multiple sclerosis cohort
-
Trampe AK, Hemmelmann C, Stroet A, Haghikia A, Hellwig K, Wiendl H, Goelz S, Ziegler A, Gold R, Chan A: Anti-JC virus antibodies in a large German natalizumab-treated multiple sclerosis cohort. Neurology 2012; 78: 1736-1742.
-
(2012)
Neurology
, vol.78
, pp. 1736-1742
-
-
Trampe, A.K.1
Hemmelmann, C.2
Stroet, A.3
Haghikia, A.4
Hellwig, K.5
Wiendl, H.6
Goelz, S.7
Ziegler, A.8
Gold, R.9
Chan, A.10
-
19
-
-
84861022041
-
Risk of natalizumab-associated progressive multifocal leukoencephalopathy
-
Bloomgren G, Richman S, Hotermans C, Subramanyam M, Goelz S, Natarajan A, Lee S, Plavina T, Scanlon JV, Sandrock A, Bozic C: Risk of natalizumab-associated progressive multifocal leukoencephalopathy. N Engl J Med 2012; 366: 1870-1880.
-
(2012)
N Engl J Med
, vol.366
, pp. 1870-1880
-
-
Bloomgren, G.1
Richman, S.2
Hotermans, C.3
Subramanyam, M.4
Goelz, S.5
Natarajan, A.6
Lee, S.7
Plavina, T.8
Scanlon, J.V.9
Sandrock, A.10
Bozic, C.11
-
20
-
-
84906569062
-
Effects of vedolizumab induction therapy for patients with Crohn's disease in whom tumor necrosis factor antagonist treatment failed
-
e3
-
Sands BE, Feagan BG, Rutgeerts P, Colombel JF, Sandborn WJ, Sy R, D'Haens G, Ben-Horin S, Xu J, Rosario M, Fox I, Parikh A, Milch C, Hanauer S: Effects of vedolizumab induction therapy for patients with Crohn's disease in whom tumor necrosis factor antagonist treatment failed. Gastroenterology 2014; 147: 618-627.e3.
-
(2014)
Gastroenterology
, vol.147
, pp. 618-627
-
-
Sands, B.E.1
Feagan, B.G.2
Rutgeerts, P.3
Colombel, J.F.4
Sandborn, W.J.5
Sy, R.6
D'Haens, G.7
Ben-Horin, S.8
Xu, J.9
Rosario, M.10
Fox, I.11
Parikh, A.12
Milch, C.13
Hanauer, S.14
-
21
-
-
84929084606
-
Vedolizumab for induction and maintenance of remission in ulcerative colitis: A Cochrane systematic review and meta-analysis
-
Mosli MH, MacDonald JK, Bickston SJ, Behm BW, Tsoulis DJ, Cheng J, Khanna R, Feagan BG: Vedolizumab for induction and maintenance of remission in ulcerative colitis: a Cochrane systematic review and meta-analysis. Inflamm Bowel Dis 2015; 21: 1151-1159.
-
(2015)
Inflamm Bowel Dis
, vol.21
, pp. 1151-1159
-
-
Mosli, M.H.1
MacDonald, J.K.2
Bickston, S.J.3
Behm, B.W.4
Tsoulis, D.J.5
Cheng, J.6
Khanna, R.7
Feagan, B.G.8
-
22
-
-
84931563838
-
Population pharmacokinetics-pharmacodynamics of vedolizumab in patients with ulcerative colitis and Crohn's disease
-
Rosario M, Dirks NL, Gastonguay MR, Fasanmade AA, Wyant T, Parikh A, Sandborn WJ, Feagan BG, Reinisch W, Fox I: Population pharmacokinetics-pharmacodynamics of vedolizumab in patients with ulcerative colitis and Crohn's disease. Aliment Pharmacol Ther 2015; 42: 188-202.
-
(2015)
Aliment Pharmacol Ther
, vol.42
, pp. 188-202
-
-
Rosario, M.1
Dirks, N.L.2
Gastonguay, M.R.3
Fasanmade, A.A.4
Wyant, T.5
Parikh, A.6
Sandborn, W.J.7
Feagan, B.G.8
Reinisch, W.9
Fox, I.10
-
23
-
-
20444469332
-
Treatment of ulcerative colitis with a humanized antibody to the alpha4beta7 integrin
-
Feagan BG, Greenberg GR, Wild G, Fedorak RN, Pare P, McDonald JW, Dube R, Cohen A, Steinhart AH, Landau S, Aguzzi RA, Fox IH, Vandervoort MK: Treatment of ulcerative colitis with a humanized antibody to the alpha4beta7 integrin. N Engl J Med 2005; 352: 2499-2507.
-
(2005)
N Engl J Med
, vol.352
, pp. 2499-2507
-
-
Feagan, B.G.1
Greenberg, G.R.2
Wild, G.3
Fedorak, R.N.4
Pare, P.5
McDonald, J.W.6
Dube, R.7
Cohen, A.8
Steinhart, A.H.9
Landau, S.10
Aguzzi, R.A.11
Fox, I.H.12
Vandervoort, M.K.13
-
24
-
-
57249089077
-
Treatment of active Crohn's disease with MLN0002, a humanized antibody to the alpha4beta7 integrin
-
Feagan BG, Greenberg GR, Wild G, Fedorak RN, Pare P, McDonald JW, Cohen A, Bitton A, Baker J, Dube R, Landau SB, Vandervoort MK, Parikh A. Treatment of active Crohn's disease with MLN0002, a humanized antibody to the alpha4beta7 integrin. Clin Gastroenterol Hepatol 2008; 6: 1370-1377.
-
(2008)
Clin Gastroenterol Hepatol
, vol.6
, pp. 1370-1377
-
-
Feagan, B.G.1
Greenberg, G.R.2
Wild, G.3
Fedorak, R.N.4
Pare, P.5
McDonald, J.W.6
Cohen, A.7
Bitton, A.8
Baker, J.9
Dube, R.10
Landau, S.B.11
Vandervoort, M.K.12
Parikh, A.13
-
25
-
-
84960145681
-
The safety of vedolizumab for ulcerative colitis and Crohn's disease
-
pii:gutjnl-2015-311079
-
Colombel JF, Sands BE, Rutgeerts P, Sandborn W, Danese S, D'Haens G, Panaccione R, Loftus EV Jr, Sankoh S, Fox I, Parikh A, Milch C, Abhyankar B, Feagan BG: The safety of vedolizumab for ulcerative colitis and Crohn's disease. Gut 2016;pii:gutjnl-2015-311079.
-
(2016)
Gut
-
-
Colombel, J.F.1
Sands, B.E.2
Rutgeerts, P.3
Sandborn, W.4
Danese, S.5
D'Haens, G.6
Panaccione, R.7
Loftus, E.V.8
Sankoh, S.9
Fox, I.10
Parikh, A.11
Milch, C.12
Abhyankar, B.13
Feagan, B.G.14
-
26
-
-
84886788747
-
Vedolizumab, a monoclonal antibody to the gut homing α4β7 integrin, does not affect cerebrospinal fluid T-lymphocyte immunophenotype
-
Milch C, Wyant T, Xu J, Parikh A, Kent W, Fox I, Berger J: Vedolizumab, a monoclonal antibody to the gut homing α4β7 integrin, does not affect cerebrospinal fluid T-lymphocyte immunophenotype. J Neuroimmunol 2013; 264: 123-126.
-
(2013)
J Neuroimmunol
, vol.264
, pp. 123-126
-
-
Milch, C.1
Wyant, T.2
Xu, J.3
Parikh, A.4
Kent, W.5
Fox, I.6
Berger, J.7
-
27
-
-
84874280106
-
Antagonizing the α4β1 integrin, but not α4β7, inhibits leukocytic infiltration of the central nervous system in rhesus monkey experimental autoimmune encephalomyelitis
-
Haanstra KG, Hofman SO, Lopes Estevao DM, Blezer EL, Bauer J, Yang LL, Wyant T, Csizmadia V, 't Hart BA, Fedyk ER: Antagonizing the α4β1 integrin, but not α4β7, inhibits leukocytic infiltration of the central nervous system in rhesus monkey experimental autoimmune encephalomyelitis. J Immunol 2013; 190: 1961-1973.
-
(2013)
J Immunol
, vol.190
, pp. 1961-1973
-
-
Haanstra, K.G.1
Hofman, S.O.2
Lopes Estevao, D.M.3
Blezer, E.L.4
Bauer, J.5
Yang, L.L.6
Wyant, T.7
Csizmadia, V.8
'T Hart, B.A.9
Fedyk, E.R.10
-
28
-
-
84904747073
-
Vedolizumab affects antibody responses to immunisation selectively in the gastrointestinal tract: Randomised controlled trial results
-
Wyant T, Leach T, Sankoh S, Wang Y, Paolino J, Pasetti MF, Feagan BG, Parikh A: Vedolizumab affects antibody responses to immunisation selectively in the gastrointestinal tract: randomised controlled trial results. Gut 2015; 64: 77-83.
-
(2015)
Gut
, vol.64
, pp. 77-83
-
-
Wyant, T.1
Leach, T.2
Sankoh, S.3
Wang, Y.4
Paolino, J.5
Pasetti, M.F.6
Feagan, B.G.7
Parikh, A.8
-
29
-
-
84880254401
-
A randomised phase I study of etrolizumab (rhuMAb β7) in moderate to severe ulcerative colitis
-
Rutgeerts PJ, Fedorak RN, Hommes DW, Sturm A, Baumgart DC, Bressler B, Schreiber S, Mansfield JC, Williams M, Tang M, Visich J, Wei X, Keir M, Luca D, Danilenko D, Egen J, O'Byrne S: A randomised phase I study of etrolizumab (rhuMAb β7) in moderate to severe ulcerative colitis. Gut 2013; 62: 1122-1130.
-
(2013)
Gut
, vol.62
, pp. 1122-1130
-
-
Rutgeerts, P.J.1
Fedorak, R.N.2
Hommes, D.W.3
Sturm, A.4
Baumgart, D.C.5
Bressler, B.6
Schreiber, S.7
Mansfield, J.C.8
Williams, M.9
Tang, M.10
Visich, J.11
Wei, X.12
Keir, M.13
Luca, D.14
Danilenko, D.15
Egen, J.16
O'Byrne, S.17
-
30
-
-
84861318436
-
Targeting leukocyte migration and adhesion in Crohn's disease and ulcerative colitis
-
Thomas S, Baumgart DC: Targeting leukocyte migration and adhesion in Crohn's disease and ulcerative colitis. Inflammopharmacology 2012; 20: 1-18.
-
(2012)
Inflammopharmacology
, vol.20
, pp. 1-18
-
-
Thomas, S.1
Baumgart, D.C.2
-
31
-
-
84959576380
-
Association between response to etrolizumab and expression of integrin αe and granzyme A in colon biopsies of patients with ulcerative colitis
-
Tew GW, Hackney JA, Gibbons D, Lamb CA, Luca D, Egen JG, Diehl L, Eastham Anderson J, Vermeire S, Mansfield JC, Feagan BG, Panes J, Baumgart DC, Schreiber S, Dotan I, Sandborn WJ, Kirby JA, Irving PM, De Hertogh G, Van Assche GA, Rutgeerts P, O'Byrne S, Hayday A, Keir ME: Association between response to etrolizumab and expression of integrin αE and granzyme A in colon biopsies of patients with ulcerative colitis. Gastroenterology 2016; 150: 477-487.
-
(2016)
Gastroenterology
, vol.150
, pp. 477-487
-
-
Tew, G.W.1
Hackney, J.A.2
Gibbons, D.3
Lamb, C.A.4
Luca, D.5
Egen, J.G.6
Diehl, L.7
Eastham Anderson, J.8
Vermeire, S.9
Mansfield, J.C.10
Feagan, B.G.11
Panes, J.12
Baumgart, D.C.13
Schreiber, S.14
Dotan, I.15
Sandborn, W.J.16
Kirby, J.A.17
Irving, P.M.18
De Hertogh, G.19
Van Assche, G.A.20
Rutgeerts, P.21
O'Byrne, S.22
Hayday, A.23
Keir, M.E.24
more..
-
32
-
-
68549135114
-
Pharmacological characterization of PF-00547659, an anti-human MAdCAM monoclonal antibody
-
Pullen N, Molloy E, Carter D, Syntin P, Clemo F, Finco-Kent D, Reagan W, Zhao S, Kawabata T, Sreckovic S: Pharmacological characterization of PF-00547659, an anti-human MAdCAM monoclonal antibody. Br J Pharmacol 2009; 157: 281-293.
-
(2009)
Br J Pharmacol
, vol.157
, pp. 281-293
-
-
Pullen, N.1
Molloy, E.2
Carter, D.3
Syntin, P.4
Clemo, F.5
Finco-Kent, D.6
Reagan, W.7
Zhao, S.8
Kawabata, T.9
Sreckovic, S.10
-
33
-
-
77957244016
-
Characterization of CCX282-B, an orally bioavailable antagonist of the CCR9 chemokine receptor, for treatment of inflammatory bowel disease
-
Walters MJ, Wang Y, Lai N, Baumgart T, Zhao BN, Dairaghi DJ, Bekker P, Ertl LS, Penfold ME, Jaen JC, Keshav S, Wendt E, Pennell A, Ungashe S, Wei Z, Wright JJ, Schall TJ: Characterization of CCX282-B, an orally bioavailable antagonist of the CCR9 chemokine receptor, for treatment of inflammatory bowel disease. J Pharmacol Exp Ther 2010; 335: 61-69.
-
(2010)
J Pharmacol Exp Ther
, vol.335
, pp. 61-69
-
-
Walters, M.J.1
Wang, Y.2
Lai, N.3
Baumgart, T.4
Zhao, B.N.5
Dairaghi, D.J.6
Bekker, P.7
Ertl, L.S.8
Penfold, M.E.9
Jaen, J.C.10
Keshav, S.11
Wendt, E.12
Pennell, A.13
Ungashe, S.14
Wei, Z.15
Wright, J.J.16
Schall, T.J.17
-
34
-
-
84946565146
-
OZANIMOD sphingosine 1-phosphate receptors 1 and 5 (S1P(1) and S1P(5)) modulator treatment of multiple sclerosis treatment of inflammatory bowel disease
-
Gras J: OZANIMOD sphingosine 1-phosphate receptors 1 and 5 (S1P(1) and S1P(5)) modulator treatment of multiple sclerosis treatment of inflammatory bowel disease. Drug Future 2015; 40: 575-581.
-
(2015)
Drug Future
, vol.40
, pp. 575-581
-
-
Gras, J.1
-
35
-
-
84968903266
-
Ozanimod induction and maintenance treatment for ulcerative colitis
-
Sandborn WJ, Feagan BG, Wolf DC, D'Haens G, Vermeire S, Hanauer SB, Ghosh S, Smith H, Cravets M, Frohna PA, Aranda R, Gujrathi S, Olson A; TOUCHSTONE Study Group: Ozanimod induction and maintenance treatment for ulcerative colitis. N Engl J Med 2016; 374: 1754-1762.
-
(2016)
N Engl J Med
, vol.374
, pp. 1754-1762
-
-
Sandborn, W.J.1
Feagan, B.G.2
Wolf, D.C.3
D'Haens, G.4
Vermeire, S.5
Hanauer, S.B.6
Ghosh, S.7
Smith, H.8
Cravets, M.9
Frohna, P.A.10
Aranda, R.11
Gujrathi, S.12
Olson, A.13
-
36
-
-
84960483909
-
Safety and efficacy of the selective sphingosine 1-phosphate receptor modulator ozanimod in relapsing multiple sclerosis (RADIANCE): A randomised, placebo-controlled, phase 2 trial
-
Cohen JA, Arnold DL, Comi G, Bar-Or A, Gujrathi S, Hartung JP, Cravets M, Olson A, Frohna PA, Selmaj KW; RADIANCE Study Group: Safety and efficacy of the selective sphingosine 1-phosphate receptor modulator ozanimod in relapsing multiple sclerosis (RADIANCE): a randomised, placebo-controlled, phase 2 trial. Lancet Neurol 2016; 15: 373-381.
-
(2016)
Lancet Neurol
, vol.15
, pp. 373-381
-
-
Cohen, J.A.1
Arnold, D.L.2
Comi, G.3
Bar-Or, A.4
Gujrathi, S.5
Hartung, J.P.6
Cravets, M.7
Olson, A.8
Frohna, P.A.9
Selmaj, K.W.10
-
37
-
-
0036790088
-
Dose ranging pharmacokinetic trial of highdose alicaforsen (intercellular adhesion molecule-1 antisense oligodeoxynucleotide) (ISIS 2302) in active Crohn's disease
-
Yacyshyn BR, Barish C, Goff J, Dalke D, Gaspari M, Yu R, Tami J, Dorr FA, Sewell KL: Dose ranging pharmacokinetic trial of highdose alicaforsen (intercellular adhesion molecule-1 antisense oligodeoxynucleotide) (ISIS 2302) in active Crohn's disease. Aliment Pharmacol Ther 2002; 16: 1761-1770.
-
(2002)
Aliment Pharmacol Ther
, vol.16
, pp. 1761-1770
-
-
Yacyshyn, B.R.1
Barish, C.2
Goff, J.3
Dalke, D.4
Gaspari, M.5
Yu, R.6
Tami, J.7
Dorr, F.A.8
Sewell, K.L.9
|