Relationship between passive permeability and molecular polarity using block relevance analysis

Molecular Pharmaceutics

Volumn 14, Issue 2, 2017, Pages 386-393

  Goetz, Gilles H ^b   Shalaeva, Marina ^b   Caron, Giulia ^a   Ermondi, Giuseppe ^a   Philippe, Laurence ^b  

^a UNIVERSITY OF TURIN   (Italy)

^b PFIZER INC   (United States)

Author keywords

Block relevance analysis; EPSA; Lipophilicity; Passive permeability; Polarity; SFC

Indexed keywords

ANIMAL CELL; ARTICLE; CELL MEMBRANE PERMEABILITY; COLORECTAL CANCER CELL LINE; DRUG PENETRATION; FORCE; HUMAN; HUMAN CELL; HYDROPHILICITY; KIDNEY CELL; LIPOPHILICITY; MDCK CELL LINE; MOLECULAR INTERACTION; NONHUMAN; PASSIVE TRANSPORT; PRIORITY JOURNAL; SURFACE AREA; ANIMAL; CACO-2 CELL LINE; CELL LINE; CHEMICAL PHENOMENA; DOG; METABOLISM; PERMEABILITY; TRANSPORT AT THE CELLULAR LEVEL; TUMOR CELL LINE;

DRUG;

ANIMALS; BIOLOGICAL TRANSPORT; CACO-2 CELLS; CELL LINE; CELL LINE, TUMOR; DOGS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MADIN DARBY CANINE KIDNEY CELLS; PERMEABILITY; PHARMACEUTICAL PREPARATIONS;

EID: 85011655898     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/acs.molpharmaceut.6b00724     Document Type: Article

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