The Block Relevance (BR) analysis to aid medicinal chemists to determine and interpret lipophilicity

MedChemComm

Volumn 4, Issue 10, 2013, Pages 1376-1381

  Caron, Giulia ^a   Vallaro, Maura ^a   Ermondi, Giuseppe ^a  

^a UNIVERSITY OF TURIN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84884780155     PISSN: 20402503     EISSN: 20402511     Source Type: Journal    
DOI: 10.1039/c3md00140g     Document Type: Article

References (27)

1. J. Arnott S. Planey Expert Opin. Drug Discovery 2012 7 863
2. F. Lombardo M. Shalaeva K. Tupper F. Gao M. Abraham J. Med. Chem. 2000 43 2922
3. S. K. Poole C. F. Poole J. Chromatogr., B: Anal. Technol. Biomed. Life Sci. 2003 797 3
4. K. Valko J. Chromatogr., A 2004 1037 299
5. G. Caron, and G. Ermondi, Lipophilicity: Chemical Nature and Biological Relevance, in Molecular Drug Properties-Measurement and Prediction, ed., R. Mannhold, Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany, 2008, 10.1002/9783527621286.ch12
6. M. Shalaeva G. Caron Y. A. Abramov T. N. O'Connell M. S. Plummer G. Yalamanchi K. A. Farley G. H. Goetz L. Philippe M. J. Shapiro J. Med. Chem. 2013 56 12 4870
7. S. Martel, D. Guillarme, Y. Henchoz, A. Galland, J.-L. Veuthey, S. Rudaz and P.-A. Carrupt, Chromatographic Approaches for Measuring Log P, in Molecular Drug Properties-Measurement and Prediction, ed., R. Mannhold, Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany, 2008, 10.1002/9783527621286.ch13
8. A. Nasal D. Siluk R. Kaliszan Curr. Med. Chem. 2003 10 381
9. S. Gocan G. Cimpan J. Comer Adv. Chromatogr. 2006 44 79
10. M. Abraham Chem. Soc. Rev. 1993 22 73
11. M. Abraham H. Chada R. Leitao R. Mitchell W. Lambert R. Kaliszan A. Nasal P. Haber J. Chromatogr., A 1997 766 35
12. M. Abraham W. Acree A. Leo D. Hoekman J. Cavanaugh J. Pharm. Sci. 2010 99 2492
13. P. Goodford J. Med. Chem. 1985 28 849
14. D. Boobbyer P. Goodford P. Mcwhinnie R. Wade J. Med. Chem. 1989 32 1083
15. R. Wade P. Goodford J. Med. Chem. 1993 36 148
16. G. Cruciani P. Crivori P.-A. Carrupt B. Testa J. Mol. Struct. 2000 17 30
17. P. Crivori G. Cruciani P. A. Carrupt B. Testa J. Med. Chem. 2000 43 2204
18. G. Caron G. Ermondi J. Med. Chem. 2005 48 3269
19. G. Ermondi G. Caron M. Ravera E. Gabano S. Bianco J. Platts D. Osella Dalton Trans. 2013 42 3482
20. G. Ermondi G. Caron J. Chromatogr., A 2012 1252 84
21. S. Wold M. Sjostrom L. Eriksson Chemom. Intell. Lab. Syst. 2001 58 109
22. T. Scior J. L. Medina-Franco Q.-T. Do K. Martínez-Mayorga J. A. Yunes Rojas P. Bernard Curr. Med. Chem. 2009 16 4297
23. A. Tropsha P. Gramatica V. K. Gombar QSAR Comb. Sci. 2003 22 69
24. G. Caron G. Ermondi Mini-Rev. Med. Chem. 2003 3 821 830
25. N. Dias N. Nawas C. Poole Analyst 2003 128 427
26. A. Pagliara E. Khamis A. Trinh P.-A. Carrupt R.-S. Tsai B. Testa J. Liq. Chromatogr. 1995 18 1721
27. R. Kaliszan Chem. Rev. 2007 107 3212