메뉴 건너뛰기




Volumn 93, Issue 4, 2017, Pages 867-881.e6

Axonal Endoplasmic Reticulum Ca2+ Content Controls Release Probability in CNS Nerve Terminals

Author keywords

Ca2+ imaging; ER GCaMP; GCaMP6; low affinity Ca2+ indicator; presynaptic endoplasmic reticulum; STIM1

Indexed keywords

SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; STROMAL INTERACTION MOLECULE 1; CALCIUM; CALCIUM CHANNEL;

EID: 85011277900     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2017.01.010     Document Type: Article
Times cited : (192)

References (77)
  • 1
    • 0031593899 scopus 로고    scopus 로고
    • Functional measurements of [Ca2+] in the endoplasmic reticulum using a herpes virus to deliver targeted aequorin
    • Alonso, M.T., Barrero, M.J., Carnicero, E., Montero, M., Garcia-Sancho, J., Alvarez, J., Functional measurements of [Ca2+] in the endoplasmic reticulum using a herpes virus to deliver targeted aequorin. Cell Calcium 24 (1998), 87–96.
    • (1998) Cell Calcium , vol.24 , pp. 87-96
    • Alonso, M.T.1    Barrero, M.J.2    Carnicero, E.3    Montero, M.4    Garcia-Sancho, J.5    Alvarez, J.6
  • 2
    • 84904734010 scopus 로고    scopus 로고
    • Intrinsic variability in Pv, RRP size, Ca(2+) channel repertoire, and presynaptic potentiation in individual synaptic boutons
    • Ariel, P., Hoppa, M.B., Ryan, T.A., Intrinsic variability in Pv, RRP size, Ca(2+) channel repertoire, and presynaptic potentiation in individual synaptic boutons. Front. Synaptic Neurosci., 4, 2013, 9.
    • (2013) Front. Synaptic Neurosci. , vol.4 , pp. 9
    • Ariel, P.1    Hoppa, M.B.2    Ryan, T.A.3
  • 3
    • 79959630005 scopus 로고    scopus 로고
    • Synaptic vesicle retrieval time is a cell-wide rather than individual-synapse property
    • Armbruster, M., Ryan, T.A., Synaptic vesicle retrieval time is a cell-wide rather than individual-synapse property. Nat. Neurosci. 14 (2011), 824–826.
    • (2011) Nat. Neurosci. , vol.14 , pp. 824-826
    • Armbruster, M.1    Ryan, T.A.2
  • 5
    • 61849142791 scopus 로고    scopus 로고
    • Calcium signaling and neurodegenerative diseases
    • Bezprozvanny, I., Calcium signaling and neurodegenerative diseases. Trends Mol. Med. 15 (2009), 89–100.
    • (2009) Trends Mol. Med. , vol.15 , pp. 89-100
    • Bezprozvanny, I.1
  • 6
    • 78650415043 scopus 로고    scopus 로고
    • Hereditary spastic paraplegias: membrane traffic and the motor pathway
    • Blackstone, C., O'Kane, C.J., Reid, E., Hereditary spastic paraplegias: membrane traffic and the motor pathway. Nat. Rev. Neurosci. 12 (2011), 31–42.
    • (2011) Nat. Rev. Neurosci. , vol.12 , pp. 31-42
    • Blackstone, C.1    O'Kane, C.J.2    Reid, E.3
  • 7
    • 0038573741 scopus 로고    scopus 로고
    • Presence and functional significance of presynaptic ryanodine receptors
    • Bouchard, R., Pattarini, R., Geiger, J.D., Presence and functional significance of presynaptic ryanodine receptors. Prog. Neurobiol. 69 (2003), 391–418.
    • (2003) Prog. Neurobiol. , vol.69 , pp. 391-418
    • Bouchard, R.1    Pattarini, R.2    Geiger, J.D.3
  • 8
    • 63049139104 scopus 로고    scopus 로고
    • Molecular clustering of STIM1 with Orai1/CRACM1 at the plasma membrane depends dynamically on depletion of Ca2+ stores and on electrostatic interactions
    • Calloway, N., Vig, M., Kinet, J.P., Holowka, D., Baird, B., Molecular clustering of STIM1 with Orai1/CRACM1 at the plasma membrane depends dynamically on depletion of Ca2+ stores and on electrostatic interactions. Mol. Biol. Cell 20 (2009), 389–399.
    • (2009) Mol. Biol. Cell , vol.20 , pp. 389-399
    • Calloway, N.1    Vig, M.2    Kinet, J.P.3    Holowka, D.4    Baird, B.5
  • 9
    • 84938942822 scopus 로고    scopus 로고
    • The active-zone protein Munc13 controls the use-dependence of presynaptic voltage-gated calcium channels
    • Calloway, N., Gouzer, G., Xue, M., Ryan, T.A., The active-zone protein Munc13 controls the use-dependence of presynaptic voltage-gated calcium channels. eLife, 4, 2015, e07728.
    • (2015) eLife , vol.4 , pp. e07728
    • Calloway, N.1    Gouzer, G.2    Xue, M.3    Ryan, T.A.4
  • 10
    • 0036139984 scopus 로고    scopus 로고
    • Assessing the role of calcium-induced calcium release in short-term presynaptic plasticity at excitatory central synapses
    • Carter, A.G., Vogt, K.E., Foster, K.A., Regehr, W.G., Assessing the role of calcium-induced calcium release in short-term presynaptic plasticity at excitatory central synapses. J. Neurosci. 22 (2002), 21–28.
    • (2002) J. Neurosci. , vol.22 , pp. 21-28
    • Carter, A.G.1    Vogt, K.E.2    Foster, K.A.3    Regehr, W.G.4
  • 12
    • 0035195395 scopus 로고    scopus 로고
    • Synapsin dispersion and reclustering during synaptic activity
    • Chi, P., Greengard, P., Ryan, T.A., Synapsin dispersion and reclustering during synaptic activity. Nat. Neurosci. 4 (2001), 1187–1193.
    • (2001) Nat. Neurosci. , vol.4 , pp. 1187-1193
    • Chi, P.1    Greengard, P.2    Ryan, T.A.3
  • 13
    • 68649116755 scopus 로고    scopus 로고
    • SR/ER-mitochondrial local communication: calcium and ROS
    • Csordás, G., Hajnóczky, G., SR/ER-mitochondrial local communication: calcium and ROS. Biochim. Biophys. Acta 1787 (2009), 1352–1362.
    • (2009) Biochim. Biophys. Acta , vol.1787 , pp. 1352-1362
    • Csordás, G.1    Hajnóczky, G.2
  • 15
    • 84874635112 scopus 로고    scopus 로고
    • Constitutive endocytosis and turnover of the neuronal glycine transporter GlyT2 is dependent on ubiquitination of a C-terminal lysine cluster
    • de Juan-Sanz, J., Núñez, E., López-Corcuera, B., Aragón, C., Constitutive endocytosis and turnover of the neuronal glycine transporter GlyT2 is dependent on ubiquitination of a C-terminal lysine cluster. PLoS ONE, 8, 2013, e58863.
    • (2013) PLoS ONE , vol.8 , pp. e58863
    • de Juan-Sanz, J.1    Núñez, E.2    López-Corcuera, B.3    Aragón, C.4
  • 18
    • 0035132863 scopus 로고    scopus 로고
    • Calcium stores in hippocampal synaptic boutons mediate short-term plasticity, store-operated Ca2+ entry, and spontaneous transmitter release
    • Emptage, N.J., Reid, C.A., Fine, A., Calcium stores in hippocampal synaptic boutons mediate short-term plasticity, store-operated Ca2+ entry, and spontaneous transmitter release. Neuron 29 (2001), 197–208.
    • (2001) Neuron , vol.29 , pp. 197-208
    • Emptage, N.J.1    Reid, C.A.2    Fine, A.3
  • 19
    • 34248584090 scopus 로고    scopus 로고
    • Inositol trisphosphate receptor Ca2+ release channels
    • Foskett, J.K., White, C., Cheung, K.H., Mak, D.O., Inositol trisphosphate receptor Ca2+ release channels. Physiol. Rev. 87 (2007), 593–658.
    • (2007) Physiol. Rev. , vol.87 , pp. 593-658
    • Foskett, J.K.1    White, C.2    Cheung, K.H.3    Mak, D.O.4
  • 21
    • 84912552965 scopus 로고    scopus 로고
    • STIM1-mediated bidirectional regulation of Ca(2+) entry through voltage-gated calcium channels (VGCC) and calcium-release activated channels (CRAC)
    • Harraz, O.F., Altier, C., STIM1-mediated bidirectional regulation of Ca(2+) entry through voltage-gated calcium channels (VGCC) and calcium-release activated channels (CRAC). Front. Cell. Neurosci., 8, 2014, 43.
    • (2014) Front. Cell. Neurosci. , vol.8 , pp. 43
    • Harraz, O.F.1    Altier, C.2
  • 25
    • 0018254261 scopus 로고
    • Endoplasmic reticulum sequesters calcium in the squid giant axon
    • Henkart, M.P., Reese, T.S., Brinley, F.J. Jr., Endoplasmic reticulum sequesters calcium in the squid giant axon. Science 202 (1978), 1300–1303.
    • (1978) Science , vol.202 , pp. 1300-1303
    • Henkart, M.P.1    Reese, T.S.2    Brinley, F.J.3
  • 26
    • 84929316222 scopus 로고    scopus 로고
    • Store-operated calcium entry: Mechanisms and modulation
    • Hogan, P.G., Rao, A., Store-operated calcium entry: Mechanisms and modulation. Biochem. Biophys. Res. Commun. 460 (2015), 40–49.
    • (2015) Biochem. Biophys. Res. Commun. , vol.460 , pp. 40-49
    • Hogan, P.G.1    Rao, A.2
  • 28
    • 84861947988 scopus 로고    scopus 로고
    • α2δ expression sets presynaptic calcium channel abundance and release probability
    • Hoppa, M.B., Lana, B., Margas, W., Dolphin, A.C., Ryan, T.A., α2δ expression sets presynaptic calcium channel abundance and release probability. Nature 486 (2012), 122–125.
    • (2012) Nature , vol.486 , pp. 122-125
    • Hoppa, M.B.1    Lana, B.2    Margas, W.3    Dolphin, A.C.4    Ryan, T.A.5
  • 29
    • 78149435362 scopus 로고    scopus 로고
    • Regulation of STIM1 and SOCE by the ubiquitin-proteasome system (UPS)
    • Keil, J.M., Shen, Z., Briggs, S.P., Patrick, G.N., Regulation of STIM1 and SOCE by the ubiquitin-proteasome system (UPS). PLoS ONE, 5, 2010, e13465.
    • (2010) PLoS ONE , vol.5 , pp. e13465
    • Keil, J.M.1    Shen, Z.2    Briggs, S.P.3    Patrick, G.N.4
  • 30
    • 0028016049 scopus 로고
    • Changes in free calcium in the endoplasmic reticulum of living cells detected using targeted aequorin
    • Kendall, J.M., Badminton, M.N., Dormer, R.L., Campbell, A.K., Changes in free calcium in the endoplasmic reticulum of living cells detected using targeted aequorin. Anal. Biochem. 221 (1994), 173–181.
    • (1994) Anal. Biochem. , vol.221 , pp. 173-181
    • Kendall, J.M.1    Badminton, M.N.2    Dormer, R.L.3    Campbell, A.K.4
  • 31
    • 84877932096 scopus 로고    scopus 로고
    • Balance of calcineurin Aα and CDK5 activities sets release probability at nerve terminals
    • Kim, S.H., Ryan, T.A., Balance of calcineurin Aα and CDK5 activities sets release probability at nerve terminals. J. Neurosci. 33 (2013), 8937–8950.
    • (2013) J. Neurosci. , vol.33 , pp. 8937-8950
    • Kim, S.H.1    Ryan, T.A.2
  • 35
    • 0036095866 scopus 로고    scopus 로고
    • Calcium signaling at single mossy fiber presynaptic terminals in the rat hippocampus
    • Liang, Y., Yuan, L.L., Johnston, D., Gray, R., Calcium signaling at single mossy fiber presynaptic terminals in the rat hippocampus. J. Neurophysiol. 87 (2002), 1132–1137.
    • (2002) J. Neurophysiol. , vol.87 , pp. 1132-1137
    • Liang, Y.1    Yuan, L.L.2    Johnston, D.3    Gray, R.4
  • 36
    • 21844432686 scopus 로고    scopus 로고
    • STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx
    • Liou, J., Kim, M.L., Heo, W.D., Jones, J.T., Myers, J.W., Ferrell, J.E. Jr., Meyer, T., STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx. Curr. Biol. 15 (2005), 1235–1241.
    • (2005) Curr. Biol. , vol.15 , pp. 1235-1241
    • Liou, J.1    Kim, M.L.2    Heo, W.D.3    Jones, J.T.4    Myers, J.W.5    Ferrell, J.E.6    Meyer, T.7
  • 37
  • 38
    • 0026514824 scopus 로고
    • Microdomains of high calcium concentration in a presynaptic terminal
    • Llinás, R., Sugimori, M., Silver, R.B., Microdomains of high calcium concentration in a presynaptic terminal. Science 256 (1992), 677–679.
    • (1992) Science , vol.256 , pp. 677-679
    • Llinás, R.1    Sugimori, M.2    Silver, R.B.3
  • 39
    • 47949132511 scopus 로고    scopus 로고
    • Oligomerization of STIM1 couples ER calcium depletion to CRAC channel activation
    • Luik, R.M., Wang, B., Prakriya, M., Wu, M.M., Lewis, R.S., Oligomerization of STIM1 couples ER calcium depletion to CRAC channel activation. Nature 454 (2008), 538–542.
    • (2008) Nature , vol.454 , pp. 538-542
    • Luik, R.M.1    Wang, B.2    Prakriya, M.3    Wu, M.M.4    Lewis, R.S.5
  • 40
    • 84952629974 scopus 로고    scopus 로고
    • SOCE in neurons: Signaling or just refilling?
    • Majewski, L., Kuznicki, J., SOCE in neurons: Signaling or just refilling?. Biochim. Biophys. Acta 1853 (2015), 1940–1952.
    • (2015) Biochim. Biophys. Acta , vol.1853 , pp. 1940-1952
    • Majewski, L.1    Kuznicki, J.2
  • 41
    • 57049143140 scopus 로고    scopus 로고
    • Mitochondria in neuroplasticity and neurological disorders
    • Mattson, M.P., Gleichmann, M., Cheng, A., Mitochondria in neuroplasticity and neurological disorders. Neuron 60 (2008), 748–766.
    • (2008) Neuron , vol.60 , pp. 748-766
    • Mattson, M.P.1    Gleichmann, M.2    Cheng, A.3
  • 43
    • 0030610646 scopus 로고    scopus 로고
    • Fluorescent indicators for Ca2+ based on green fluorescent proteins and calmodulin
    • Miyawaki, A., Llopis, J., Heim, R., McCaffery, J.M., Adams, J.A., Ikura, M., Tsien, R.Y., Fluorescent indicators for Ca2+ based on green fluorescent proteins and calmodulin. Nature 388 (1997), 882–887.
    • (1997) Nature , vol.388 , pp. 882-887
    • Miyawaki, A.1    Llopis, J.2    Heim, R.3    McCaffery, J.M.4    Adams, J.A.5    Ikura, M.6    Tsien, R.Y.7
  • 46
    • 80053310677 scopus 로고    scopus 로고
    • SOC and now also SIC: store-operated and store-inhibited channels
    • Moreno, C., Vaca, L., SOC and now also SIC: store-operated and store-inhibited channels. IUBMB Life 63 (2011), 856–863.
    • (2011) IUBMB Life , vol.63 , pp. 856-863
    • Moreno, C.1    Vaca, L.2
  • 47
    • 0023652396 scopus 로고
    • A C-terminal signal prevents secretion of luminal ER proteins
    • Munro, S., Pelham, H.R., A C-terminal signal prevents secretion of luminal ER proteins. Cell 48 (1987), 899–907.
    • (1987) Cell , vol.48 , pp. 899-907
    • Munro, S.1    Pelham, H.R.2
  • 49
    • 84901825346 scopus 로고    scopus 로고
    • Molecular aspects of hereditary spastic paraplegia
    • Noreau, A., Dion, P.A., Rouleau, G.A., Molecular aspects of hereditary spastic paraplegia. Exp. Cell Res. 325 (2014), 18–26.
    • (2014) Exp. Cell Res. , vol.325 , pp. 18-26
    • Noreau, A.1    Dion, P.A.2    Rouleau, G.A.3
  • 50
  • 51
    • 10644234677 scopus 로고    scopus 로고
    • Bcl-2-mediated alterations in endoplasmic reticulum Ca2+ analyzed with an improved genetically encoded fluorescent sensor
    • Palmer, A.E., Jin, C., Reed, J.C., Tsien, R.Y., Bcl-2-mediated alterations in endoplasmic reticulum Ca2+ analyzed with an improved genetically encoded fluorescent sensor. Proc. Natl. Acad. Sci. USA 101 (2004), 17404–17409.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 17404-17409
    • Palmer, A.E.1    Jin, C.2    Reed, J.C.3    Tsien, R.Y.4
  • 52
    • 77957332175 scopus 로고    scopus 로고
    • The CRAC channel activator STIM1 binds and inhibits L-type voltage-gated calcium channels
    • Park, C.Y., Shcheglovitov, A., Dolmetsch, R., The CRAC channel activator STIM1 binds and inhibits L-type voltage-gated calcium channels. Science 330 (2010), 101–105.
    • (2010) Science , vol.330 , pp. 101-105
    • Park, C.Y.1    Shcheglovitov, A.2    Dolmetsch, R.3
  • 53
    • 0042035632 scopus 로고    scopus 로고
    • Capacitative calcium entry in the nervous system
    • Putney, J.W. Jr., Capacitative calcium entry in the nervous system. Cell Calcium 34 (2003), 339–344.
    • (2003) Cell Calcium , vol.34 , pp. 339-344
    • Putney, J.W.1
  • 54
    • 84894150737 scopus 로고    scopus 로고
    • Activity-driven local ATP synthesis is required for synaptic function
    • Rangaraju, V., Calloway, N., Ryan, T.A., Activity-driven local ATP synthesis is required for synaptic function. Cell 156 (2014), 825–835.
    • (2014) Cell , vol.156 , pp. 825-835
    • Rangaraju, V.1    Calloway, N.2    Ryan, T.A.3
  • 57
    • 0033803597 scopus 로고    scopus 로고
    • The use of pHluorins for optical measurements of presynaptic activity
    • Sankaranarayanan, S., De Angelis, D., Rothman, J.E., Ryan, T.A., The use of pHluorins for optical measurements of presynaptic activity. Biophys. J. 79 (2000), 2199–2208.
    • (2000) Biophys. J. , vol.79 , pp. 2199-2208
    • Sankaranarayanan, S.1    De Angelis, D.2    Rothman, J.E.3    Ryan, T.A.4
  • 58
    • 0034710645 scopus 로고    scopus 로고
    • Intracellular calcium dependence of transmitter release rates at a fast central synapse
    • Schneggenburger, R., Neher, E., Intracellular calcium dependence of transmitter release rates at a fast central synapse. Nature 406 (2000), 889–893.
    • (2000) Nature , vol.406 , pp. 889-893
    • Schneggenburger, R.1    Neher, E.2
  • 60
    • 0037083746 scopus 로고    scopus 로고
    • Ca(2+) dynamics in the lumen of the endoplasmic reticulum in sensory neurons: direct visualization of Ca(2+)-induced Ca(2+) release triggered by physiological Ca(2+) entry
    • Solovyova, N., Veselovsky, N., Toescu, E.C., Verkhratsky, A., Ca(2+) dynamics in the lumen of the endoplasmic reticulum in sensory neurons: direct visualization of Ca(2+)-induced Ca(2+) release triggered by physiological Ca(2+) entry. EMBO J. 21 (2002), 622–630.
    • (2002) EMBO J. , vol.21 , pp. 622-630
    • Solovyova, N.1    Veselovsky, N.2    Toescu, E.C.3    Verkhratsky, A.4
  • 61
    • 0030804808 scopus 로고    scopus 로고
    • The calcium channel and the organization of the presynaptic transmitter release face
    • Stanley, E.F., The calcium channel and the organization of the presynaptic transmitter release face. Trends Neurosci. 20 (1997), 404–409.
    • (1997) Trends Neurosci. , vol.20 , pp. 404-409
    • Stanley, E.F.1
  • 62
    • 53149128421 scopus 로고    scopus 로고
    • Structural and mechanistic insights into STIM1-mediated initiation of store-operated calcium entry
    • Stathopulos, P.B., Zheng, L., Li, G.Y., Plevin, M.J., Ikura, M., Structural and mechanistic insights into STIM1-mediated initiation of store-operated calcium entry. Cell 135 (2008), 110–122.
    • (2008) Cell , vol.135 , pp. 110-122
    • Stathopulos, P.B.1    Zheng, L.2    Li, G.Y.3    Plevin, M.J.4    Ikura, M.5
  • 63
    • 79960672046 scopus 로고    scopus 로고
    • Endoplasmic reticulum Ca(2+) handling in excitable cells in health and disease
    • Stutzmann, G.E., Mattson, M.P., Endoplasmic reticulum Ca(2+) handling in excitable cells in health and disease. Pharmacol. Rev. 63 (2011), 700–727.
    • (2011) Pharmacol. Rev. , vol.63 , pp. 700-727
    • Stutzmann, G.E.1    Mattson, M.P.2
  • 64
  • 65
    • 42049090126 scopus 로고    scopus 로고
    • Mitochondria: the hub of cellular Ca2+ signaling
    • Szabadkai, G., Duchen, M.R., Mitochondria: the hub of cellular Ca2+ signaling. Physiology (Bethesda) 23 (2008), 84–94.
    • (2008) Physiology (Bethesda) , vol.23 , pp. 84-94
    • Szabadkai, G.1    Duchen, M.R.2
  • 66
    • 34848904785 scopus 로고    scopus 로고
    • Motor neuron disease-associated mutant vesicle-associated membrane protein-associated protein (VAP) B recruits wild-type VAPs into endoplasmic reticulum-derived tubular aggregates
    • Teuling, E., Ahmed, S., Haasdijk, E., Demmers, J., Steinmetz, M.O., Akhmanova, A., Jaarsma, D., Hoogenraad, C.C., Motor neuron disease-associated mutant vesicle-associated membrane protein-associated protein (VAP) B recruits wild-type VAPs into endoplasmic reticulum-derived tubular aggregates. J. Neurosci. 27 (2007), 9801–9815.
    • (2007) J. Neurosci. , vol.27 , pp. 9801-9815
    • Teuling, E.1    Ahmed, S.2    Haasdijk, E.3    Demmers, J.4    Steinmetz, M.O.5    Akhmanova, A.6    Jaarsma, D.7    Hoogenraad, C.C.8
  • 67
    • 0017031603 scopus 로고
    • Three-dimensional distribution of smooth endoplasmic reticulum in myelinated axons
    • Tsukita, S., Ishikawa, H., Three-dimensional distribution of smooth endoplasmic reticulum in myelinated axons. J. Electron Microsc. (Tokyo) 25 (1976), 141–149.
    • (1976) J. Electron Microsc. (Tokyo) , vol.25 , pp. 141-149
    • Tsukita, S.1    Ishikawa, H.2
  • 68
    • 12944314765 scopus 로고    scopus 로고
    • Physiology and pathophysiology of the calcium store in the endoplasmic reticulum of neurons
    • Verkhratsky, A., Physiology and pathophysiology of the calcium store in the endoplasmic reticulum of neurons. Physiol. Rev. 85 (2005), 201–279.
    • (2005) Physiol. Rev. , vol.85 , pp. 201-279
    • Verkhratsky, A.1
  • 69
    • 33745494172 scopus 로고    scopus 로고
    • Distinct endocytic pathways control the rate and extent of synaptic vesicle protein recycling
    • Voglmaier, S.M., Kam, K., Yang, H., Fortin, D.L., Hua, Z., Nicoll, R.A., Edwards, R.H., Distinct endocytic pathways control the rate and extent of synaptic vesicle protein recycling. Neuron 51 (2006), 71–84.
    • (2006) Neuron , vol.51 , pp. 71-84
    • Voglmaier, S.M.1    Kam, K.2    Yang, H.3    Fortin, D.L.4    Hua, Z.5    Nicoll, R.A.6    Edwards, R.H.7
  • 71
    • 84883766736 scopus 로고    scopus 로고
    • Presenilins regulate calcium homeostasis and presynaptic function via ryanodine receptors in hippocampal neurons
    • Wu, B., Yamaguchi, H., Lai, F.A., Shen, J., Presenilins regulate calcium homeostasis and presynaptic function via ryanodine receptors in hippocampal neurons. Proc. Natl. Acad. Sci. USA 110 (2013), 15091–15096.
    • (2013) Proc. Natl. Acad. Sci. USA , vol.110 , pp. 15091-15096
    • Wu, B.1    Yamaguchi, H.2    Lai, F.A.3    Shen, J.4
  • 75
    • 27144515996 scopus 로고    scopus 로고
    • STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane
    • Zhang, S.L., Yu, Y., Roos, J., Kozak, J.A., Deerinck, T.J., Ellisman, M.H., Stauderman, K.A., Cahalan, M.D., STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane. Nature 437 (2005), 902–905.
    • (2005) Nature , vol.437 , pp. 902-905
    • Zhang, S.L.1    Yu, Y.2    Roos, J.3    Kozak, J.A.4    Deerinck, T.J.5    Ellisman, M.H.6    Stauderman, K.A.7    Cahalan, M.D.8
  • 77
    • 79952171014 scopus 로고    scopus 로고
    • Auto-inhibitory role of the EF-SAM domain of STIM proteins in store-operated calcium entry
    • Zheng, L., Stathopulos, P.B., Schindl, R., Li, G.Y., Romanin, C., Ikura, M., Auto-inhibitory role of the EF-SAM domain of STIM proteins in store-operated calcium entry. Proc. Natl. Acad. Sci. USA 108 (2011), 1337–1342.
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 1337-1342
    • Zheng, L.1    Stathopulos, P.B.2    Schindl, R.3    Li, G.Y.4    Romanin, C.5    Ikura, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.