Mechanisms by Which Dietary Antioxidants May Prevent Cardiovascular Diseases

Journal of Medicinal Food

Volumn 1, Issue 1, 1998, Pages 45-51

  Parthasarathy, Sampath ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 85011162273     PISSN: 1096620X     EISSN: 15577600     Source Type: Journal    
DOI: 10.1089/jmf.1998.1.45     Document Type: Article

References (49)

1. Ares, M. P., Kallin, B., Eriksson, P., and Nilsson, J. (1995). Oxidized LDL induces transcription factor activator protein-1 but inhibits activation of nuclear factor-kappa B in human vascular smooth muscle cells. Arterioscler Thromb Vase Biol 15, 1584–1590.
2. Aviram, M., Dankner, G., and Brook, J. G. (1990). Platelet secretory products increase low density lipoprotein oxidation, enhance its uptake by macrophages, and reduce its fluidity. Arteriosclerosis 10, 559–563.
3. Baila, G., Jacob, H. S., Eaton, J. W., Belcher, J. D., and Vercellotti, G. M. (1991). Hemin: A possible physiological mediator of low density lipoprotein oxidation and endothelial injury. Arterioscler Thromb 11, 1700–1711.
4. Berliner, J. A., Navab, M., Fogelman, A. M., Frank, J. S., Demer, L. L., Edwards, P. A., Watson, A. D., and Lusis, A. J. (1995). Atherosclerosis: Basic mechanisms. Oxidation, inflammation, and genetics. Circulation 91, 2488–2496.
5. Berliner, J. A., Territo, M., Almada, L., Carter, A., Shafonsky, E., and Fogelman, A. M. (1986). Monocyte chemotactic factor produced by large vessel endothelial cells in vitro. Arteriosclerosis 6, 254–258.
6. Berliner, J. A., Territo, M. C., Sevanian, A., Ramin, S., Kim, J. A., Bamshad, B., Esterson, M., and Fogelman, A. M. (1990). Minimally modified low density lipoprotein stimulates monocyte endothelial interactions. J Clin Invest 85, 1260–1266.
7. Bowry, V. W., Ingold, K. U., and Stocker, R. (1992). Vitamin E in human low-density lipoprotein: When and how this antioxidant becomes a pro-oxidant. Biochem J 288, 341–344.
8. Brennan, P. and O'Neill, L. A. (1995). Effects of oxidants and antioxidants on nuclear factor kappa B activation in three different cell lines: Evidence against a universal hypothesis involving oxygen radicals. Biochim Biophys Acta 1260, 167–175.
9. Coffey, M. D., Cole, R. A., Colles, S. M., and Chisolm, G. M. (1995). In vitro cell injury by oxidized low density lipoprotein involves lipid hydroperoxide-induced formation of alkoxyl, lipid, and peroxyl radicals. J Clin Invest 96, 1866–1873.
10. Cushing, S. D., Berliner, J. A., Valente, A. J., Territo, M. C., Navab, M., Parhami, F., Gerrity, R., Schwartz, C. J., and Fogelman, A. M. (1990). Minimally modified low density lipoprotein induces monocyte chemotactic protein 1 in human endothelial cells and smooth muscle cells. Proc Natl Acad Sci USA. 87, 5134–5138.
11. Darley-Usmar, V. M., Lelchuk, R., O'Leary, V. J., Knowles, M., Rogers, M. V., and Severn, A. (1990). Oxidation of low-density lipoprotein and macrophage-derived foam cells. Biochem Soc Trans 18, 1064–1066.
12. Esterbauer, H., Schmidt, R., and Hayn, M. (1997). Relationships among oxidation of low-density lipoprotein, antioxidant protection, and atherosclerosis [review]. Adv Pharmacol 38, 425–456.
13. Frostegard, J., Nilsson, J., Haegerstrand, A., Hamsten, A., Wigzell, H., and Gidlund, M. (1990). Oxidized low density lipoprotein induces differentiation and adhesion of human monocytes and the monocytic cell line U937. Proc Natl Acad Sci USA. 87, 904–908.
14. Fruebis, J., Steinberg, D., Dresel, H. A., and Carew, T. E. (1994). A comparison of the antiatherogenic effects of probucol and of a structural analogue of probucol in low density lipoprotein receptor-deficient rabbits. J Clin Invest 94, 392–398.
15. Gey, K. F. (1990). The antioxidant hypothesis of cardiovascular disease: Epidemiology and mechanisms. Biochem Soc Trans 18, 1041–1045.
16. Greenspan, P., Ryu, B. H., Mao, F., and Gutman, R. L. (1995). Association of negatively-charged phospholipids with low-density lipoprotein (LDL) increases its uptake and the deposition of cholesteryl esters by macrophages. Biochim Biophys Acta 1257, 257–264.
17. Haberland, M. E., Rasmussen, R. R., Olch, C. L., and Fogelman, A. M. (1986). Two distinct receptors account for recognition of maleyl-albumin in human monocytes during differentiation in vitro. J Clin Invest 77, 681–689.
18. Hayes, K. C., Pronczuk, A., and Liang, J. S. (1993). Differences in the plasma transport and tissue concentrations of tocopherols and tocotrients: Observations in humans and hamsters. Proc Soc exp Biol Med 202, 353–359.
19. Jialal, I. and Fuller, C. J. (1995). Errect of vitamin E, vitamin C and beta-carotene on LDL oxidation and atherosclerosis [review]. Can J Cardiol 11(Suppl G), 97G-103G.
20. Kamido, H., Kuksis, A., Marai, L., and Myher, J. J. (1992). Identification of cholesterol-bound aldehydes in copper-oxidized low density lipoprotein. FEBS Lett 304, 269–272.
21. Khan, B. V., Parthasarathy, S., Alexander, R. W., and Medford, R. M. (1995). Modified low density lipoprotein and its constituents augment cytokine-activated vascular cell adhesion molecule-1 gene expression in human vascular endothelial cells. J Clin Invest 95, 1262–1270.
22. Kim, J. G., Sabbagh, F., Santanam, N., Wilcox, J. N., Medford, R. M., and Parthasarathy, S. (1997). Generation of a polyclonal antibody against lipid peroxide-mediated proteins. Free Radie Biol Med 23, 251–259.
23. Liu, K. Z., Ramjiawan, B., Kutryk, M. J., and Pierce, G. N. (1991). Effects of oxidative modification of cholesterol in isolated low density lipoproteins on cultured smooth muscle cells. Mol Cell Biochem 108, 49–56.
24. MacAuley, D. (1993). Exercise, cardiovascular disease and lipids [review]. Br J Clin Pract 47, 323–327.
25. Manson, J. E., Gaziano, J. M., Jonas, M. A., and Hennekens, C. H. (1993). Antioxidants and cardiovascular disease: A review. J Am Coll Nutr 12, 426–432.
26. McCusker, K. and Hoidal, J. (1989). Characterization of scavenger receptor activity in resident human lung macrophages. Exp Lung Res 15, 651–661.
27. Myers, D. E., Huang, W. N., and Larkins, R. G. (1996). Lipoprotein-induced prostacyclin production in endothelial cells and effects of lipoprotein modification. Am J Physiol 271, C1504–1511.
28. Naito, C., Kawamura, M., and Yamamoto, Y. (1993). Lipid peroxides as the initiating factor of atherosclerosis [review]. Ann N Y Acad Sci 676, 27–45.
29. Newby, A. C., Southgate, K. M., and Davies, M. (1994). Extracellular matrix degrading metalloproteinases in the pathogenesis of arteriosclerosis [review]. Basic Res Cardiol 89(Suppl 1), 59–70.
30. Parthasarathy, S. (1994). Modified Lipoproteins in the Pathogenesis of Atherosclerosis. (R. G. Landes Company, Austin, TX) pp. 1–125.
31. Pearson, A. M. (1996). Scavenger receptors in innate immunity, [review]. Curr Opin Immunol 8, 20–28.
32. Quinn, M. T., Parthasarathy, S., and Steinberg, D. (1988). Lysophosphatidylcholine: A chemotactic factor for human monocytes and its potential role in atherogenesis. Proc Natl Acad Sci USA. 85, 2805–2809.
33. Rajavashisth, T. B., Andalibi, A., Territo, M. C., Berliner, J. A., Navab, M., Fogelman, A. M., and Lusis, A. J. (1990). Induction of endothelial cell expression of granulocyte and macrophage colony-stimulating factors by modified low-density lipoproteins. Nature 344, 254–257.
34. Rao, G. N., Lassegue, B., Griendling, K. K., and Alexander, R. W. (1993). Hydrogen peroxide stimulates transcription of c-jun in vascular smooth muscle cells: Role of arachidonic acid. Oncogene 8, 2759–2764.
35. Rapola, J. M., Virtamo, J., Ripatti, S., Huttunen, J. K., Al-banes, D., Taylor, P. R., and Heinonen, O. P. (1997). Randomized trial of alpha-tocopherol and beta-caratone supplements on incidence of major coronary events in men with previous myocardial infarction. Lancet 349, 1715–1720.
36. Rosenfeld, M. E., Palinski, W., Yla Herttuala, S., and Carew, T. E. (1990). Macrophages, endothelial cells, and lipoprotein oxidation in the pathogenesis of atherosclerosis. Toxicol Pathol 18, 560–571.
37. Santanam, N. and Parthasarathy, S. (1995). Paradoxical actions of antioxidants in the oxidation of low density lipoprotein by peroxidases. J Clin Invest 95, 2594–2600.
38. Savenkova, M. L., Mueller, D. M., and Heinecke, J. W. (1994). Tyrosyl radical generated by myeloperoxidase is a physiological catalyst for the initiation of lipid peroxidation in low density lipoprotein. J Biol Chem 269, 20394–20400.
39. Schwenke, D. C. (1996). Antioxidants, dietary fat saturation, lipoprotein oxidation and atherogenesis [editorial]. Nutrition 12, 377–379.
40. Shah, P. K., Falk, E., Badimon, J. J., Fernandez-Ortiz, A., Mailhac, A., Villareal-Levy, G., Fallon, J. T., Regnstrom, J., and Fuster, V. (1995). Human monocyte-derived macrophages induce collagen breakdown in fibrous caps of atherosclerotic plaques: Potential role of matrix-degrading metalloproteinases and implications for plaque rupture. Circulation 92, 1565–1569.
41. Steinberg, D., Parthasarathy, S., Carew, T. E., Khoo, J. C., and Witztum, J. L. (1989). Beyond cholesterol: Modifications of low-density lipoprotein that increase its atherogenicity. N Engl J Med 320, 915–924.
42. Stephens, N. G., Parsons, A., Schofield, P. M., Kelly, F., Cheesemen, K., Mitchinson, M. J., and Brown, M. J. (1996). Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS). Lancet 347, 781–786.
43. Stringer, M. D., Gorog, P. G., Freeman, A., and Kakkar, V. V. (1989). Lipid peroxides and atherosclerosis. Biomed J 298, 281–284.
44. Szczeklik, A. and Gryglewski, R. J. (1980). Low density lipoproteins (LDL) are carriers for lipid peroxides and inhibit prostacyclin (PGI2) biosynthesis in arteries. Artery 7, 488–495.
45. Vaarala, O. (1996). Antiphospholipid antibodies and atherosclerosis. Lupus 5, 442–447.
46. Wieland, E., Parthasarathy, S., and Steinberg, D. (1993). Peroxidase-dependent metal-independent oxidation of low density lipoprotein in vitro: A model for in vivo oxidation? Proc Natl Acad Sci USA. 90, 5929–5933.
47. Yamamoto, K. and Niki, E. (1988). Interaction of alpha tocopherol with iron: Antioxidant and prooxidant effects of alpha tocopherol in the oxidation of lipids in aqueous dispersions in the presence of iron. Biochim Biophys Acta 958, 19–23.
48. Yokode, M., Nagano, Y., Arai, H., Ueyama, K., Ueda, Y., and Kita, T. (1995). Cigarette smoke and lipoprotein modification: A possible interpretation for development of atherosclerosis. Ann N Y Acad Sci 748, 294–300.
49. Yokote, K., Morisaki, N., Zenibayashi, M., Ueda, S., Kanzaki, T., Saito, Y., and Yoshida, S. (1993). The phospholipase-A2 reaction leads to increased monocyte adhesion of endothelial cells via the expression of adhesion molecules. Eur J Biochem 217, 723–729.