Optical inactivation of synaptic AMPA receptors erases fear memory

Nature Biotechnology

Volumn 35, Issue 1, 2017, Pages 38-47

  Takemoto, Kiwamu ^a,b   Iwanari, Hiroko ^c   Tada, Hirobumi ^a   Suyama, Kumiko ^a   Sano, Akane ^a   Nagai, Takeharu ^d   Hamakubo, Takao ^c   Takahashi, Takuya ^a  

^a YOKOHAMA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN; CHROMOPHORES; MONOCLONAL ANTIBODIES; PHOTOSENSITIZERS; PROPIONIC ACID; PSYCHOPHYSIOLOGY;

AMPA-RECEPTOR; ANTIBODY CONJUGATE; COGNITIVE FUNCTIONS; EXTRACELLULAR DOMAINS; MEMORY ACQUISITIONS; OPTICAL TECHNIQUE; PHYSIOLOGICAL ROLES; SYNAPTIC PROTEINS;

ANTIBODIES;

AMPA RECEPTOR; ANTIBODY CONJUGATE; EOSIN; MONOCLONAL ANTIBODY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CHROMOPHORE ASSISTED LIGHT INACTIVATION; CONTROLLED STUDY; EMBRYO; FEAR; HIPPOCAMPAL CA1 REGION; HIPPOCAMPAL NEURONAL CULTURE; IN VIVO STUDY; MALE; MEMORY; MOUSE; NONHUMAN; OPTICS; PRIORITY JOURNAL; RAT; ANIMAL; ANTAGONISTS AND INHIBITORS; HIPPOCAMPUS; INSTITUTE FOR CANCER RESEARCH MOUSE; LIGHT; METABOLISM; NERVE CELL INHIBITION; PHOTOSTIMULATION; PHYSIOLOGY; PROCEDURES; RADIATION RESPONSE; REINFORCEMENT; SYNAPSE;

ANIMALS; EXTINCTION, PSYCHOLOGICAL; FEAR; HIPPOCAMPUS; LIGHT; MALE; MEMORY; MICE; MICE, INBRED ICR; NEURAL INHIBITION; PHOTIC STIMULATION; RECEPTORS, AMPA; SYNAPSES;

EID: 85011015548     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt.3710     Document Type: Article

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