-
1
-
-
0016274287
-
Hepatic ketogenesis and gluconeogenesis in humans
-
Garber AJ, Menzel PH, Boden G. Hepatic ketogenesis and gluconeogenesis in humans. J Clin Invest 1974; 54: 981–989.
-
(1974)
J Clin Invest
, vol.54
, pp. 981-989
-
-
Garber, A.J.1
Menzel, P.H.2
Boden, G.3
-
2
-
-
77952633345
-
Studies in the ketosis of fasting
-
Foster DW. Studies in the ketosis of fasting. J Clin Invest 1967; 46: 1283–1296.
-
(1967)
J Clin Invest
, vol.46
, pp. 1283-1296
-
-
Foster, D.W.1
-
3
-
-
43249084958
-
The ketogenic diet for the treatment of childhood epilepsy: a randomised controlled trial
-
Neal EG, Chaffe H, Schwartz RH. The ketogenic diet for the treatment of childhood epilepsy: a randomised controlled trial. Lancet Neurol 2008; 7: 500–506.
-
(2008)
Lancet Neurol
, vol.7
, pp. 500-506
-
-
Neal, E.G.1
Chaffe, H.2
Schwartz, R.H.3
-
4
-
-
84908007846
-
Triheptanoin for glucose transporter type I deficiency (G1D): modulation of human ictogenesis, cerebral metabolic rate, and cognitive indices by a food supplement
-
Pascual JM, Liu P, Mao D. Triheptanoin for glucose transporter type I deficiency (G1D): modulation of human ictogenesis, cerebral metabolic rate, and cognitive indices by a food supplement. JAMA Neurol 2014; 71: 1255–1265.
-
(2014)
JAMA Neurol
, vol.71
, pp. 1255-1265
-
-
Pascual, J.M.1
Liu, P.2
Mao, D.3
-
5
-
-
0018582265
-
Tomographic measurement of local cerebral glucose metabolic rate in humans with (F-18)2-fluoro-2-deoxy-D-glucose: validation of method
-
Phelps ME, Huang SC, Hoffman EJ. Tomographic measurement of local cerebral glucose metabolic rate in humans with (F-18)2-fluoro-2-deoxy-D-glucose: validation of method. Ann Neurol 1979; 6: 371–388.
-
(1979)
Ann Neurol
, vol.6
, pp. 371-388
-
-
Phelps, M.E.1
Huang, S.C.2
Hoffman, E.J.3
-
6
-
-
34547583836
-
Automated synthesis of 11C-acetoacetic acid, a key alternate brain fuel to glucose
-
Tremblay S, Ouellet R, Rodrigue S. Automated synthesis of 11C-acetoacetic acid, a key alternate brain fuel to glucose. Appl Radiat Isot 2007; 65: 934–940.
-
(2007)
Appl Radiat Isot
, vol.65
, pp. 934-940
-
-
Tremblay, S.1
Ouellet, R.2
Rodrigue, S.3
-
7
-
-
84903362456
-
Brain glucose and acetoacetate metabolism: a comparison of young and older adults
-
Nugent S, Tremblay S, Chen KW. Brain glucose and acetoacetate metabolism: a comparison of young and older adults. Neurobiol Aging 2014; 35: 1386–1395.
-
(2014)
Neurobiol Aging
, vol.35
, pp. 1386-1395
-
-
Nugent, S.1
Tremblay, S.2
Chen, K.W.3
-
8
-
-
84919917084
-
Lower brain 18F-fluorodeoxyglucose uptake but normal 11C-acetoacetate metabolism in mild Alzheimer's disease dementia
-
Castellano CA, Nugent S, Paquet N. Lower brain 18F-fluorodeoxyglucose uptake but normal 11C-acetoacetate metabolism in mild Alzheimer's disease dementia. J Alzheimers Dis 2015; 43: 1343–1353.
-
(2015)
J Alzheimers Dis
, vol.43
, pp. 1343-1353
-
-
Castellano, C.A.1
Nugent, S.2
Paquet, N.3
-
9
-
-
62449142597
-
The role of metabolic disorders in Alzheimer disease and vascular dementia: two roads converged
-
Craft S. The role of metabolic disorders in Alzheimer disease and vascular dementia: two roads converged. Arch Neurol 2009; 66: 300–305.
-
(2009)
Arch Neurol
, vol.66
, pp. 300-305
-
-
Craft, S.1
-
10
-
-
84954271182
-
Can ketones compensate for deteriorating brain glucose uptake during aging? Implications for the risk and treatment of Alzheimer's disease
-
Cunnane SC, Courchesne-Loyer A, St-Pierre V. Can ketones compensate for deteriorating brain glucose uptake during aging? Implications for the risk and treatment of Alzheimer's disease. Ann N Y Acad Sci 2016; 1367: 12–20.
-
(2016)
Ann N Y Acad Sci
, vol.1367
, pp. 12-20
-
-
Cunnane, S.C.1
Courchesne-Loyer, A.2
St-Pierre, V.3
-
11
-
-
0034844219
-
Ketone bodies, potential therapeutic uses
-
Veech RL, Chance B, Kashiwaya Y. Ketone bodies, potential therapeutic uses. IUBMB Life 2001; 51: 241–247.
-
(2001)
IUBMB Life
, vol.51
, pp. 241-247
-
-
Veech, R.L.1
Chance, B.2
Kashiwaya, Y.3
-
12
-
-
78649962844
-
Brain fuel metabolism, aging, and Alzheimer's disease
-
Cunnane S, Nugent S, Roy M. Brain fuel metabolism, aging, and Alzheimer's disease. Nutrition 2011; 27: 3–20.
-
(2011)
Nutrition
, vol.27
, pp. 3-20
-
-
Cunnane, S.1
Nugent, S.2
Roy, M.3
-
13
-
-
0029894079
-
Changes in cerebral blood flow and carbohydrate metabolism during acute hyperketonemia
-
Hasselbalch SG, Madsen PL, Hageman LP. Changes in cerebral blood flow and carbohydrate metabolism during acute hyperketonemia. Am J Physiol 1996; 270(5 Pt 1): E746–E751.
-
(1996)
Am J Physiol
, vol.270
, Issue.5
, pp. E746-E751
-
-
Hasselbalch, S.G.1
Madsen, P.L.2
Hageman, L.P.3
-
14
-
-
0036293650
-
Effect of acute hyperketonemia on the cerebral uptake of ketone bodies in nondiabetic subjects and IDDM patients
-
Blomqvist G, Alvarsson M, Grill V. Effect of acute hyperketonemia on the cerebral uptake of ketone bodies in nondiabetic subjects and IDDM patients. Am J Physiol Endocrinol Metab 2002; 283: E20–E28.
-
(2002)
Am J Physiol Endocrinol Metab
, vol.283
, pp. E20-E28
-
-
Blomqvist, G.1
Alvarsson, M.2
Grill, V.3
-
15
-
-
79957963820
-
Mild experimental ketosis increases brain uptake of (11)C-acetoacetate and (18)F-fluorodeoxyglucose: a dual-tracer PET imaging study in rats
-
Pifferi F, Tremblay S, Croteau E. Mild experimental ketosis increases brain uptake of (11)C-acetoacetate and (18)F-fluorodeoxyglucose: a dual-tracer PET imaging study in rats. Nutr Neurosci 2011; 14: 51–58.
-
(2011)
Nutr Neurosci
, vol.14
, pp. 51-58
-
-
Pifferi, F.1
Tremblay, S.2
Croteau, E.3
-
16
-
-
84869095794
-
The ketogenic diet increases brain glucose and ketone uptake in aged rats: a dual tracer PET and volumetric MRI study
-
Roy M, Nugent S, Tremblay-Mercier J. The ketogenic diet increases brain glucose and ketone uptake in aged rats: a dual tracer PET and volumetric MRI study. Brain Res 2012; 1488: 14–23.
-
(2012)
Brain Res
, vol.1488
, pp. 14-23
-
-
Roy, M.1
Nugent, S.2
Tremblay-Mercier, J.3
-
18
-
-
0015413298
-
Resistance to symptomatic insulin reactions after fasting
-
Drenick EJ, Alvarez LC, Tamasi GC. Resistance to symptomatic insulin reactions after fasting. J Clin Invest 1972; 51: 2757–2562.
-
(1972)
J Clin Invest
, vol.51
, pp. 2562-2757
-
-
Drenick, E.J.1
Alvarez, L.C.2
Tamasi, G.C.3
-
19
-
-
0019521834
-
Cerebral blood flow and metabolic rate of oxygen, glucose, lactate, pyruvate, ketone bodies and amino acids
-
Lying-Tunell U, Lindblad BS, Malmlund HO. Cerebral blood flow and metabolic rate of oxygen, glucose, lactate, pyruvate, ketone bodies and amino acids. Acta Neurol Scand 1981; 63: 337–350.
-
(1981)
Acta Neurol Scand
, vol.63
, pp. 337-350
-
-
Lying-Tunell, U.1
Lindblad, B.S.2
Malmlund, H.O.3
-
20
-
-
0003685387
-
-
10th ed, Philadelphia, W.B. Saunders Company
-
Mahan LK, Escott-Stump S. Krause's food, nutrition, & diet therapy, 10th ed. Philadelphia: W.B. Saunders Company, 2000.
-
(2000)
Krause's food, nutrition, & diet therapy
-
-
Mahan, L.K.1
Escott-Stump, S.2
-
22
-
-
0021262232
-
The Harris Benedict equation reevaluated: resting energy requirements and the body cell mass
-
Roza AM, Shizgal HM. The Harris Benedict equation reevaluated: resting energy requirements and the body cell mass. Am J Clin Nutr 1984; 40: 168–182.
-
(1984)
Am J Clin Nutr
, vol.40
, pp. 168-182
-
-
Roza, A.M.1
Shizgal, H.M.2
-
23
-
-
41649106122
-
An optimized blockwise nonlocal means denoising filter for 3-D magnetic resonance images
-
Coupe P, Yger P, Prima S. An optimized blockwise nonlocal means denoising filter for 3-D magnetic resonance images. IEEE Trans Med Imaging 2008; 27: 425–441.
-
(2008)
IEEE Trans Med Imaging
, vol.27
, pp. 425-441
-
-
Coupe, P.1
Yger, P.2
Prima, S.3
-
24
-
-
84933676657
-
Using fMRI non-local means denoising to uncover activation in sub-cortical structures at 1.5 T for guided HARDI tractography
-
Bernier M, Chamberland M, Houde JC. Using fMRI non-local means denoising to uncover activation in sub-cortical structures at 1.5 T for guided HARDI tractography. Front Hum Neurosci 2014; 8: 715.
-
(2014)
Front Hum Neurosci
, vol.8
, pp. 715
-
-
Bernier, M.1
Chamberland, M.2
Houde, J.C.3
-
25
-
-
80053564195
-
Image-derived input function for brain PET studies: many challenges and few opportunities
-
Zanotti-Fregonara P, Chen K, Liow JS. Image-derived input function for brain PET studies: many challenges and few opportunities. J Cereb Blood Flow Metab 2011; 31: 1986–1998.
-
(2011)
J Cereb Blood Flow Metab
, vol.31
, pp. 1986-1998
-
-
Zanotti-Fregonara, P.1
Chen, K.2
Liow, J.S.3
-
26
-
-
0020956774
-
Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data
-
Patlak CS, Blasberg RG, Fenstermacher JD. Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data. J Cereb Blood Flow Metab 1983; 3: 1–7.
-
(1983)
J Cereb Blood Flow Metab
, vol.3
, pp. 1-7
-
-
Patlak, C.S.1
Blasberg, R.G.2
Fenstermacher, J.D.3
-
27
-
-
0036733752
-
The FDG lumped constant in normal human brain
-
Graham MM, Muzi M, Spence AM. The FDG lumped constant in normal human brain. J Nucl Med 2002; 43: 1157–1166.
-
(2002)
J Nucl Med
, vol.43
, pp. 1157-1166
-
-
Graham, M.M.1
Muzi, M.2
Spence, A.M.3
-
28
-
-
0019202402
-
Direct, fixed-time kinetic assays for beta-hydroxybutyrate and acetoacetate with a centrifugal analyzer or a computer-backed spectrophotometer
-
Li PK, Lee JT, MacGillivray MH. Direct, fixed-time kinetic assays for beta-hydroxybutyrate and acetoacetate with a centrifugal analyzer or a computer-backed spectrophotometer. Clin Chem 1980; 26: 1713–1717.
-
(1980)
Clin Chem
, vol.26
, pp. 1713-1717
-
-
Li, P.K.1
Lee, J.T.2
MacGillivray, M.H.3
-
29
-
-
0022260035
-
Direct automated assay method for serum or urine levels of ketone bodies
-
Harano Y, Ohtsuki M, Ida M. Direct automated assay method for serum or urine levels of ketone bodies. Clin Chim Acta 1985; 151: 177–183.
-
(1985)
Clin Chim Acta
, vol.151
, pp. 177-183
-
-
Harano, Y.1
Ohtsuki, M.2
Ida, M.3
-
31
-
-
77953730768
-
Bezafibrate mildly stimulates ketogenesis and fatty acid metabolism in hypertriglyceridemic subjects
-
Tremblay-Mercier J, Tessier D, Plourde M. Bezafibrate mildly stimulates ketogenesis and fatty acid metabolism in hypertriglyceridemic subjects. J Pharmacol Exp Ther 2010; 334: 341–346.
-
(2010)
J Pharmacol Exp Ther
, vol.334
, pp. 341-346
-
-
Tremblay-Mercier, J.1
Tessier, D.2
Plourde, M.3
-
32
-
-
0015040664
-
Utilization of non-esterified fatty acids and ketone nbodies in human brain
-
Gottstein U, Muller W, Berghoff W. Utilization of non-esterified fatty acids and ketone nbodies in human brain. Klin Wochenschr 1971; 49: 406–411.
-
(1971)
Klin Wochenschr
, vol.49
, pp. 406-411
-
-
Gottstein, U.1
Muller, W.2
Berghoff, W.3
-
33
-
-
0035829361
-
Controlling the false discovery rate in behavior genetics research
-
Benjamini Y, Drai D, Elmer G. Controlling the false discovery rate in behavior genetics research. Behav Brain Res 2001; 125: 279–284.
-
(2001)
Behav Brain Res
, vol.125
, pp. 279-284
-
-
Benjamini, Y.1
Drai, D.2
Elmer, G.3
-
34
-
-
0022552442
-
Regional ketone body utilization by rat brain in starvation and diabetes
-
Hawkins RA, Mans AM, Davis DW. Regional ketone body utilization by rat brain in starvation and diabetes. Am J Physiol 1986; 250: E169–E178.
-
(1986)
Am J Physiol
, vol.250
, pp. E169-E178
-
-
Hawkins, R.A.1
Mans, A.M.2
Davis, D.W.3
-
35
-
-
85021156164
-
The ketogenic diet in epilepsy
-
A DB
-
A DB. The ketogenic diet in epilepsy. Can Med Assoc J 1931; 24: 106–107.
-
(1931)
Can Med Assoc J
, vol.24
, pp. 106-107
-
-
-
36
-
-
77952549736
-
Ketogenic diets: an historical antiepileptic therapy with promising potentialities for the aging brain
-
Balietti M, Casoli T, Di Stefano G. Ketogenic diets: an historical antiepileptic therapy with promising potentialities for the aging brain. Ageing Res Rev 2010; 9: 273–279.
-
(2010)
Ageing Res Rev
, vol.9
, pp. 273-279
-
-
Balietti, M.1
Casoli, T.2
Di Stefano, G.3
-
37
-
-
84881148989
-
Ketosis proportionately spares glucose utilization in brain
-
Zhang Y, Kuang Y, Xu K. Ketosis proportionately spares glucose utilization in brain. J Cereb Blood Flow Metab 2013; 33: 1307–1311.
-
(2013)
J Cereb Blood Flow Metab
, vol.33
, pp. 1307-1311
-
-
Zhang, Y.1
Kuang, Y.2
Xu, K.3
-
39
-
-
33947261376
-
Hypometabolism exceeds atrophy in presymptomatic early-onset familial Alzheimer's disease
-
Mosconi L, Sorbi S, de Leon MJ. Hypometabolism exceeds atrophy in presymptomatic early-onset familial Alzheimer's disease. J Nucl Med 2006; 47: 1778–1786.
-
(2006)
J Nucl Med
, vol.47
, pp. 1778-1786
-
-
Mosconi, L.1
Sorbi, S.2
de Leon, M.J.3
-
40
-
-
78651274000
-
Insulin resistance and Alzheimer-like reductions in regional cerebral glucose metabolism for cognitively normal adults with prediabetes or early type 2 diabetes
-
Baker LD, Cross DJ, Minoshima S. Insulin resistance and Alzheimer-like reductions in regional cerebral glucose metabolism for cognitively normal adults with prediabetes or early type 2 diabetes. Arch Neurol 2011; 68: 51–57.
-
(2011)
Arch Neurol
, vol.68
, pp. 51-57
-
-
Baker, L.D.1
Cross, D.J.2
Minoshima, S.3
-
41
-
-
0347719366
-
Functional brain abnormalities in young adults at genetic risk for late-onset Alzheimer's dementia
-
Reiman EM, Chen K, Alexander GE. Functional brain abnormalities in young adults at genetic risk for late-onset Alzheimer's dementia. Proc Natl Acad Sci USA 2004; 101: 284–289.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 284-289
-
-
Reiman, E.M.1
Chen, K.2
Alexander, G.E.3
-
42
-
-
84865529158
-
Clinical and biomarker changes in dominantly inherited Alzheimer's disease
-
Bateman RJ, Xiong C, Benzinger TL. Clinical and biomarker changes in dominantly inherited Alzheimer's disease. N Engl J Med 2012; 367: 795–804.
-
(2012)
N Engl J Med
, vol.367
, pp. 795-804
-
-
Bateman, R.J.1
Xiong, C.2
Benzinger, T.L.3
-
43
-
-
84955416036
-
Relationship of metabolic and endocrine parameters to brain glucose metabolism in older adults: do cognitively-normal older adults have a particular metabolic phenotype?
-
Nugent S, Castellano CA, Bocti C. Relationship of metabolic and endocrine parameters to brain glucose metabolism in older adults: do cognitively-normal older adults have a particular metabolic phenotype? Biogerontology 2016; 17: 241–255.
-
(2016)
Biogerontology
, vol.17
, pp. 241-255
-
-
Nugent, S.1
Castellano, C.A.2
Bocti, C.3
-
44
-
-
84875368921
-
Stimulation of mild, sustained ketonemia by medium-chain triacylglycerols in healthy humans: estimated potential contribution to brain energy metabolism
-
Courchesne-Loyer A, Fortier M, Tremblay-Mercier J. Stimulation of mild, sustained ketonemia by medium-chain triacylglycerols in healthy humans: estimated potential contribution to brain energy metabolism. Nutrition 2013; 29: 635–640.
-
(2013)
Nutrition
, vol.29
, pp. 635-640
-
-
Courchesne-Loyer, A.1
Fortier, M.2
Tremblay-Mercier, J.3
-
45
-
-
0025322353
-
Ketone body kinetics in vivo using simultaneous administration of acetoacetate and 3-hydroxybutyrate labelled with stable isotopes
-
Avogaro A, Nosadini R, Bier DM. Ketone body kinetics in vivo using simultaneous administration of acetoacetate and 3-hydroxybutyrate labelled with stable isotopes. Acta Diabetol Lat 1990; 27: 41–51.
-
(1990)
Acta Diabetol Lat
, vol.27
, pp. 41-51
-
-
Avogaro, A.1
Nosadini, R.2
Bier, D.M.3
-
46
-
-
0028789091
-
Use of R-beta-[1-11C]hydroxybutyrate in PET studies of regional cerebral uptake of ketone bodies in humans
-
Blomqvist G, Thorell JO, Ingvar M. Use of R-beta-[1-11C]hydroxybutyrate in PET studies of regional cerebral uptake of ketone bodies in humans. Am J Physiol 1995; 269: E948–E959.
-
(1995)
Am J Physiol
, vol.269
, pp. E948-E959
-
-
Blomqvist, G.1
Thorell, J.O.2
Ingvar, M.3
-
48
-
-
34547624611
-
Supply and demand in cerebral energy metabolism: the role of nutrient transporters
-
Simpson IA, Carruthers A, Vannucci SJ. Supply and demand in cerebral energy metabolism: the role of nutrient transporters. J Cereb Blood Flow Metab 2007; 27: 1766–1791.
-
(2007)
J Cereb Blood Flow Metab
, vol.27
, pp. 1766-1791
-
-
Simpson, I.A.1
Carruthers, A.2
Vannucci, S.J.3
-
49
-
-
84863397848
-
The monocarboxylate transporter family – role and regulation
-
Halestrap AP, Wilson MC. The monocarboxylate transporter family – role and regulation. IUBMB Life 2012; 64: 109–119.
-
(2012)
IUBMB Life
, vol.64
, pp. 109-119
-
-
Halestrap, A.P.1
Wilson, M.C.2
|