Effect of acute hyperketonemia on the cerebral uptake of ketone bodies in nondiabetic subjects and IDDM patients

American Journal of Physiology - Endocrinology and Metabolism

Volumn 283, Issue 1 46-1, 2002, Pages

  Blomqvist, G ^a   Alvarsson, M ^b   Grill, V ^b   Von Heijne, G ^b   Ingvar, M ^b   Thorell, J O ^b   Stone Elander, S ^b   Widen L ^b   Ekberg, K ^c  

^a UPPSALA UNIVERSITY HOSPITAL   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c TRONDHEIM UNIVERSITY HOSPITAL   (Norway)

Author keywords

Blood brain barrier; Positron emission tomography; hydroxybutyrate

Indexed keywords

3 HYDROXYBUTYRIC ACID; KETONE BODY;

ADULT; ARTICLE; BLOOD BRAIN BARRIER; CITRIC ACID CYCLE; CLINICAL ARTICLE; CONTROLLED STUDY; GLUCOSE METABOLISM; GLUCOSE OXIDATION; GLUCOSE TRANSPORT; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; KETOGENESIS; KETONE BODY METABOLISM; MALE; METABOLIC RATE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL;

EID: 0036293650     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.00294.2001     Document Type: Article

References (21)

1. 11C]hydroxybutyrate in PET studies of regional cerebral uptake of ketone bodies in humans
2. Changes during development in transport processes of the blood-brain barrier
3. The estimation of rates of utilization of glucose and ketone bodies in the brain of the suckling rats using compartmental analysis of isotopic data
4. The movement of ketone bodies, glucose, pyruvate and lactate between the blood and the brain of rats
5. High- and low-affinity transport of D-glucose from blood to brain
6. Cerebral blood flow and substrate utilization in insulin-treated diabetic subjects
7. Ketone bodies as markers for type 1 (insulin dependent) diabetes and their value in the monitoring of diabetic control
8. Brain metabolism during short-term starvation in humans
9. Changes in cerebral blood flow and carbohydrate metabolism during acute hyperketonemia
10. Regional blood-brain barrier transport of ketone bodies in portacaval-shunted rats
11. CSF concentration and CSF/blood ratio of fuel related components in children after prolonged fasting
12. An algorithm for least-squares estimation on nonlinear parameters
13. Chronic hypoglycemia increases brain glucose transport
14. Measurement of human brain β-hydroxybutyrate in acute hyperketonemia
15. Human brain β-hydroxybutyrate and lactate increase in fasting-induced ketosis
16. Graphical evaluation of blood-to-brain transfer constants from multiple time uptake data
17. Physiological role of ketone bodies as substrates and signals in mammalian tissues
18. Regulation of glucose and ketone body metabolism in brain of anaesthetized rats
19. Effect of ketone body infusions on amino acid and nitrogen metabolism in man
20. 11C]-β-hydroxybutyric acid
21. The ECAT EXACT HR: Performance of a new high resolution positron scanner