-
1
-
-
84919848147
-
Hepatitis B virus infection
-
[1] Trepo, C., Chan, H.L., Lok, A., Hepatitis B virus infection. Lancet 384:9959 (2014), 2053–2063.
-
(2014)
Lancet
, vol.384
, Issue.9959
, pp. 2053-2063
-
-
Trepo, C.1
Chan, H.L.2
Lok, A.3
-
2
-
-
33748929265
-
Peginterferon alpha-2b plus adefovir induce strong cccDNA decline and HBsAg reduction in patients with chronic hepatitis B
-
[2] Wursthorn, K., Lutgehetmann, M., Dandri, M., Volz, T., Buggisch, P., Zollner, B., et al. Peginterferon alpha-2b plus adefovir induce strong cccDNA decline and HBsAg reduction in patients with chronic hepatitis B. Hepatology 44 (2006), 675–684.
-
(2006)
Hepatology
, vol.44
, pp. 675-684
-
-
Wursthorn, K.1
Lutgehetmann, M.2
Dandri, M.3
Volz, T.4
Buggisch, P.5
Zollner, B.6
-
3
-
-
84879327902
-
Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virus
-
[3] Yan, H., Zhong, G., Xu, G., He, W., Jing, Z., Gao, Z., et al. Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virus. eLife, 1, 2012, e00049.
-
(2012)
eLife
, vol.1
, pp. e00049
-
-
Yan, H.1
Zhong, G.2
Xu, G.3
He, W.4
Jing, Z.5
Gao, Z.6
-
4
-
-
84894237342
-
Hepatitis B and D viruses exploit sodium taurocholate co-transporting polypeptide for species-specific entry into hepatocytes
-
[4] Ni, Y., Lempp, F.A., Mehrle, S., Nkongolo, S., Kaufman, C., Falth, M., et al. Hepatitis B and D viruses exploit sodium taurocholate co-transporting polypeptide for species-specific entry into hepatocytes. Gastroenterology 146 (2014), 1070–1083.
-
(2014)
Gastroenterology
, vol.146
, pp. 1070-1083
-
-
Ni, Y.1
Lempp, F.A.2
Mehrle, S.3
Nkongolo, S.4
Kaufman, C.5
Falth, M.6
-
5
-
-
0033617583
-
Viral clearance without destruction of infected cells during acute HBV infection
-
[5] Guidotti, L.G., Rochford, R., Chung, J., Shapiro, M., Purcell, R., Chisari, F.V., Viral clearance without destruction of infected cells during acute HBV infection. Science 284 (1999), 825–829.
-
(1999)
Science
, vol.284
, pp. 825-829
-
-
Guidotti, L.G.1
Rochford, R.2
Chung, J.3
Shapiro, M.4
Purcell, R.5
Chisari, F.V.6
-
6
-
-
84984754046
-
State of the (research) chimp
-
[6] Harrington, M., State of the (research) chimp. Lab Animal, 41, 2012, 31.
-
(2012)
Lab Animal
, vol.41
, pp. 31
-
-
Harrington, M.1
-
7
-
-
0036297520
-
Experimental transfection of Macaca sylvanus with cloned human hepatitis B virus
-
[7] Gheit, T., Sekkat, S., Cova, L., Chevallier, M., Petit, M.A., Hantz, O., et al. Experimental transfection of Macaca sylvanus with cloned human hepatitis B virus. J Gen Virol 83 (2002), 1645–1649.
-
(2002)
J Gen Virol
, vol.83
, pp. 1645-1649
-
-
Gheit, T.1
Sekkat, S.2
Cova, L.3
Chevallier, M.4
Petit, M.A.5
Hantz, O.6
-
8
-
-
77952707314
-
Hepatitis B virus replication in primary macaque hepatocytes: crossing the species barrier toward a new small primate model
-
[8] Lucifora, J., Vincent, I.E., Berthillon, P., Dupinay, T., Michelet, M., Protzer, U., et al. Hepatitis B virus replication in primary macaque hepatocytes: crossing the species barrier toward a new small primate model. Hepatology 51 (2010), 1954–1960.
-
(2010)
Hepatology
, vol.51
, pp. 1954-1960
-
-
Lucifora, J.1
Vincent, I.E.2
Berthillon, P.3
Dupinay, T.4
Michelet, M.5
Protzer, U.6
-
9
-
-
84887016912
-
Discovery of naturally occurring transmissible chronic hepatitis B virus infection among Macaca fascicularis from Mauritius Island
-
[9] Dupinay, T., Gheit, T., Roques, P., Cova, L., Chevallier-Queyron, P., Tasahsu, S.I., et al. Discovery of naturally occurring transmissible chronic hepatitis B virus infection among Macaca fascicularis from Mauritius Island. Hepatology 58 (2013), 1610–1620.
-
(2013)
Hepatology
, vol.58
, pp. 1610-1620
-
-
Dupinay, T.1
Gheit, T.2
Roques, P.3
Cova, L.4
Chevallier-Queyron, P.5
Tasahsu, S.I.6
-
10
-
-
84880320667
-
Molecular determinants of hepatitis B and D virus entry restriction in mouse sodium taurocholate cotransporting polypeptide
-
[10] Yan, H., Peng, B., He, W., Zhong, G., Qi, Y., Ren, B., et al. Molecular determinants of hepatitis B and D virus entry restriction in mouse sodium taurocholate cotransporting polypeptide. J Virol 87 (2013), 7977–7991.
-
(2013)
J Virol
, vol.87
, pp. 7977-7991
-
-
Yan, H.1
Peng, B.2
He, W.3
Zhong, G.4
Qi, Y.5
Ren, B.6
-
11
-
-
84895536554
-
HBV life cycle is restricted in mouse hepatocytes expressing human NTCP
-
[11] Li, H., Zhuang, Q., Wang, Y., Zhang, T., Zhao, J., Zhang, Y., et al. HBV life cycle is restricted in mouse hepatocytes expressing human NTCP. Cell Mol Immunol 11 (2014), 175–183.
-
(2014)
Cell Mol Immunol
, vol.11
, pp. 175-183
-
-
Li, H.1
Zhuang, Q.2
Wang, Y.3
Zhang, T.4
Zhao, J.5
Zhang, Y.6
-
12
-
-
84938916095
-
Hepatitis B virus covalently closed circular DNA formation in immortalized mouse hepatocytes associated with nucleocapsid destabilization
-
[12] Cui, X., Guo, J.T., Hu, J., Hepatitis B virus covalently closed circular DNA formation in immortalized mouse hepatocytes associated with nucleocapsid destabilization. J Virol 89 (2015), 9021–9028.
-
(2015)
J Virol
, vol.89
, pp. 9021-9028
-
-
Cui, X.1
Guo, J.T.2
Hu, J.3
-
13
-
-
84894064916
-
Immune cell responses are not required to induce substantial hepatitis B virus antigen decline during pegylated interferon-alpha administration
-
[13] Allweiss, L., Volz, T., Lutgehetmann, M., Giersch, K., Bornscheuer, T., Lohse, A.W., et al. Immune cell responses are not required to induce substantial hepatitis B virus antigen decline during pegylated interferon-alpha administration. J Hepatol 60 (2014), 500–507.
-
(2014)
J Hepatol
, vol.60
, pp. 500-507
-
-
Allweiss, L.1
Volz, T.2
Lutgehetmann, M.3
Giersch, K.4
Bornscheuer, T.5
Lohse, A.W.6
-
14
-
-
2942532722
-
Persistence of cccDNA during the natural history of chronic hepatitis B and decline during adefovir dipivoxil therapy
-
[14] Werle-Lapostolle, B., Bowden, S., Locarnini, S., Wursthorn, K., Petersen, J., Lau, G., et al. Persistence of cccDNA during the natural history of chronic hepatitis B and decline during adefovir dipivoxil therapy. Gastroenterology 126 (2004), 1750–1758.
-
(2004)
Gastroenterology
, vol.126
, pp. 1750-1758
-
-
Werle-Lapostolle, B.1
Bowden, S.2
Locarnini, S.3
Wursthorn, K.4
Petersen, J.5
Lau, G.6
-
15
-
-
84941419474
-
A sensitive and accurate quantification method for the detection of hepatitis B virus covalently closed circular DNA by the application of a droplet digital polymerase chain reaction amplification system
-
[15] Mu, D., Yan, L., Tang, H., Liao, Y., A sensitive and accurate quantification method for the detection of hepatitis B virus covalently closed circular DNA by the application of a droplet digital polymerase chain reaction amplification system. Biotechnol Lett 37 (2015), 2063–2073.
-
(2015)
Biotechnol Lett
, vol.37
, pp. 2063-2073
-
-
Mu, D.1
Yan, L.2
Tang, H.3
Liao, Y.4
-
16
-
-
50949116278
-
Rolling circle amplification, a powerful tool for genetic and functional studies of complete hepatitis B virus genomes from low-level infections and for directly probing covalently closed circular DNA
-
[16] Margeridon, S., Carrouee-Durantel, S., Chemin, I., Barraud, L., Zoulim, F., Trepo, C., et al. Rolling circle amplification, a powerful tool for genetic and functional studies of complete hepatitis B virus genomes from low-level infections and for directly probing covalently closed circular DNA. Antimicrob Agents Chemother 52 (2008), 3068–3073.
-
(2008)
Antimicrob Agents Chemother
, vol.52
, pp. 3068-3073
-
-
Margeridon, S.1
Carrouee-Durantel, S.2
Chemin, I.3
Barraud, L.4
Zoulim, F.5
Trepo, C.6
-
17
-
-
80051679793
-
Quantitation of HBV covalently closed circular DNA in micro formalin fixed paraffin-embedded liver tissue using rolling circle amplification in combination with real-time PCR
-
[17] Zhong, Y., Han, J., Zou, Z., Liu, S., Tang, B., Ren, X., et al. Quantitation of HBV covalently closed circular DNA in micro formalin fixed paraffin-embedded liver tissue using rolling circle amplification in combination with real-time PCR. Clin Chim Acta 412 (2011), 1905–1911.
-
(2011)
Clin Chim Acta
, vol.412
, pp. 1905-1911
-
-
Zhong, Y.1
Han, J.2
Zou, Z.3
Liu, S.4
Tang, B.5
Ren, X.6
-
18
-
-
84924287298
-
A novel method for detection of HBVcccDNA in hepatocytes using rolling circle amplification combined with in situ PCR
-
[18] Zhong, Y., Hu, S., Xu, C., Zhao, Y., Xu, D., Zhao, Y., et al. A novel method for detection of HBVcccDNA in hepatocytes using rolling circle amplification combined with in situ PCR. BMC Infect Dis, 14, 2014, 608.
-
(2014)
BMC Infect Dis
, vol.14
, pp. 608
-
-
Zhong, Y.1
Hu, S.2
Xu, C.3
Zhao, Y.4
Xu, D.5
Zhao, Y.6
-
19
-
-
33644854241
-
Hepatitis B virus replication is regulated by the acetylation status of hepatitis B virus cccDNA-bound H3 and H4 histones
-
[19] Pollicino, T., Belloni, L., Raffa, G., Pediconi, N., Squadrito, G., Raimondo, G., et al. Hepatitis B virus replication is regulated by the acetylation status of hepatitis B virus cccDNA-bound H3 and H4 histones. Gastroenterology 130 (2006), 823–837.
-
(2006)
Gastroenterology
, vol.130
, pp. 823-837
-
-
Pollicino, T.1
Belloni, L.2
Raffa, G.3
Pediconi, N.4
Squadrito, G.5
Raimondo, G.6
-
20
-
-
78149319907
-
Generation of covalently closed circular DNA of hepatitis B viruses via intracellular recycling is regulated in a virus specific manner
-
[20] Kock, J., Rosler, C., Zhang, J.J., Blum, H.E., Nassal, M., Thoma, C., Generation of covalently closed circular DNA of hepatitis B viruses via intracellular recycling is regulated in a virus specific manner. PLoS Pathog, 6, 2010, e1001082.
-
(2010)
PLoS Pathog
, vol.6
, pp. e1001082
-
-
Kock, J.1
Rosler, C.2
Zhang, J.J.3
Blum, H.E.4
Nassal, M.5
Thoma, C.6
-
21
-
-
78449260869
-
Nuclear export and import of human hepatitis B virus capsid protein and particles
-
[21] Li, H.C., Huang, E.Y., Su, P.Y., Wu, S.Y., Yang, C.C., Lin, Y.S., et al. Nuclear export and import of human hepatitis B virus capsid protein and particles. PLoS Pathog, 6, 2010, e1001162.
-
(2010)
PLoS Pathog
, vol.6
, pp. e1001162
-
-
Li, H.C.1
Huang, E.Y.2
Su, P.Y.3
Wu, S.Y.4
Yang, C.C.5
Lin, Y.S.6
-
22
-
-
77649199085
-
Nucleoporin 153 arrests the nuclear import of hepatitis B virus capsids in the nuclear basket
-
[22] Schmitz, A., Schwarz, A., Foss, M., Zhou, L., Rabe, B., Hoellenriegel, J., et al. Nucleoporin 153 arrests the nuclear import of hepatitis B virus capsids in the nuclear basket. PLoS Pathog, 6, 2010, e1000741.
-
(2010)
PLoS Pathog
, vol.6
, pp. e1000741
-
-
Schmitz, A.1
Schwarz, A.2
Foss, M.3
Zhou, L.4
Rabe, B.5
Hoellenriegel, J.6
-
23
-
-
84940172646
-
HBV cccDNA: viral persistence reservoir and key obstacle for a cure of chronic hepatitis B
-
[23] Nassal, M., HBV cccDNA: viral persistence reservoir and key obstacle for a cure of chronic hepatitis B. Gut 64 (2015), 1972–1984.
-
(2015)
Gut
, vol.64
, pp. 1972-1984
-
-
Nassal, M.1
-
24
-
-
36049013787
-
Characterization of the intracellular deproteinized relaxed circular DNA of hepatitis B virus: an intermediate of covalently closed circular DNA formation
-
[24] Guo, H., Jiang, D., Zhou, T., Cuconati, A., Block, T.M., Guo, J.T., Characterization of the intracellular deproteinized relaxed circular DNA of hepatitis B virus: an intermediate of covalently closed circular DNA formation. J Virol 81 (2007), 12472–12484.
-
(2007)
J Virol
, vol.81
, pp. 12472-12484
-
-
Guo, H.1
Jiang, D.2
Zhou, T.3
Cuconati, A.4
Block, T.M.5
Guo, J.T.6
-
25
-
-
72849136702
-
Production and function of the cytoplasmic deproteinized relaxed circular DNA of hepadnaviruses
-
[25] Guo, H., Mao, R., Block, T.M., Guo, J.T., Production and function of the cytoplasmic deproteinized relaxed circular DNA of hepadnaviruses. J Virol 84 (2010), 387–396.
-
(2010)
J Virol
, vol.84
, pp. 387-396
-
-
Guo, H.1
Mao, R.2
Block, T.M.3
Guo, J.T.4
-
26
-
-
84865060138
-
Characterization of the host factors required for hepadnavirus covalently closed circular (ccc) DNA formation
-
[26] Guo, H., Xu, C., Zhou, T., Block, T.M., Guo, J.T., Characterization of the host factors required for hepadnavirus covalently closed circular (ccc) DNA formation. PLoS One, 7, 2012, e43270.
-
(2012)
PLoS One
, vol.7
, pp. e43270
-
-
Guo, H.1
Xu, C.2
Zhou, T.3
Block, T.M.4
Guo, J.T.5
-
27
-
-
84920764736
-
Involvement of the host DNA-repair enzyme TDP2 in formation of the covalently closed circular DNA persistence reservoir of hepatitis B viruses
-
[27] Koniger, C., Wingert, I., Marsmann, M., Rosler, C., Beck, J., Nassal, M., Involvement of the host DNA-repair enzyme TDP2 in formation of the covalently closed circular DNA persistence reservoir of hepatitis B viruses. Proc Natl Acad Sci U S A 111 (2014), E4244–E4253.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. E4244-E4253
-
-
Koniger, C.1
Wingert, I.2
Marsmann, M.3
Rosler, C.4
Beck, J.5
Nassal, M.6
-
28
-
-
84937889320
-
Does tyrosyl DNA phosphodiesterase-2 play a role in hepatitis B virus genome repair?
-
[28] Cui, X., McAllister, R., Boregowda, R., Sohn, J.A., Ledesma, F.C., Caldecott, K.W., et al. Does tyrosyl DNA phosphodiesterase-2 play a role in hepatitis B virus genome repair?. PLoS One, 10, 2015, e0128401.
-
(2015)
PLoS One
, vol.10
, pp. e0128401
-
-
Cui, X.1
McAllister, R.2
Boregowda, R.3
Sohn, J.A.4
Ledesma, F.C.5
Caldecott, K.W.6
-
29
-
-
0029037074
-
The covalently closed duplex form of the hepadnavirus genome exists in situ as a heterogeneous population of viral minichromosomes
-
[29] Newbold, J.E., Xin, H., Tencza, M., Sherman, G., Dean, J., Bowden, S., et al. The covalently closed duplex form of the hepadnavirus genome exists in situ as a heterogeneous population of viral minichromosomes. J Virol 69 (1995), 3350–3357.
-
(1995)
J Virol
, vol.69
, pp. 3350-3357
-
-
Newbold, J.E.1
Xin, H.2
Tencza, M.3
Sherman, G.4
Dean, J.5
Bowden, S.6
-
30
-
-
0028095561
-
Hepatitis B virus genome is organized into nucleosomes in the nucleus of the infected cell
-
[30] Bock, C.T., Schranz, P., Schroder, C.H., Zentgraf, H., Hepatitis B virus genome is organized into nucleosomes in the nucleus of the infected cell. Virus Genes 8 (1994), 215–229.
-
(1994)
Virus Genes
, vol.8
, pp. 215-229
-
-
Bock, C.T.1
Schranz, P.2
Schroder, C.H.3
Zentgraf, H.4
-
31
-
-
0035896013
-
Structural organization of the hepatitis B virus minichromosome
-
[31] Bock, C.T., Schwinn, S., Locarnini, S., Fyfe, J., Manns, M.P., Trautwein, C., et al. Structural organization of the hepatitis B virus minichromosome. J Mol Biol 307 (2001), 183–196.
-
(2001)
J Mol Biol
, vol.307
, pp. 183-196
-
-
Bock, C.T.1
Schwinn, S.2
Locarnini, S.3
Fyfe, J.4
Manns, M.P.5
Trautwein, C.6
-
32
-
-
73949127893
-
Nuclear HBx binds the HBV minichromosome and modifies the epigenetic regulation of cccDNA function
-
[32] Belloni, L., Pollicino, T., De Nicola, F., Guerrieri, F., Raffa, G., Fanciulli, M., et al. Nuclear HBx binds the HBV minichromosome and modifies the epigenetic regulation of cccDNA function. Proc Natl Acad Sci U S A 106 (2009), 19975–19979.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 19975-19979
-
-
Belloni, L.1
Pollicino, T.2
De Nicola, F.3
Guerrieri, F.4
Raffa, G.5
Fanciulli, M.6
-
33
-
-
84875772744
-
Methyltransferase PRMT1 is a binding partner of HBx and a negative regulator of hepatitis B virus transcription
-
[33] Benhenda, S., Ducroux, A., Riviere, L., Sobhian, B., Ward, M.D., Dion, S., et al. Methyltransferase PRMT1 is a binding partner of HBx and a negative regulator of hepatitis B virus transcription. J Virol 87 (2013), 4360–4371.
-
(2013)
J Virol
, vol.87
, pp. 4360-4371
-
-
Benhenda, S.1
Ducroux, A.2
Riviere, L.3
Sobhian, B.4
Ward, M.D.5
Dion, S.6
-
34
-
-
84856514985
-
IFN-alpha inhibits HBV transcription and replication in cell culture and in humanized mice by targeting the epigenetic regulation of the nuclear cccDNA minichromosome
-
[34] Belloni, L., Allweiss, L., Guerrieri, F., Pediconi, N., Volz, T., Pollicino, T., et al. IFN-alpha inhibits HBV transcription and replication in cell culture and in humanized mice by targeting the epigenetic regulation of the nuclear cccDNA minichromosome. J Clin Invest 122 (2012), 529–537.
-
(2012)
J Clin Invest
, vol.122
, pp. 529-537
-
-
Belloni, L.1
Allweiss, L.2
Guerrieri, F.3
Pediconi, N.4
Volz, T.5
Pollicino, T.6
-
35
-
-
84947466102
-
Mapping of histone modifications in episomal HBV cccDNA uncovers an unusual chromatin organization amenable to epigenetic manipulation
-
[35] Tropberger, P., Mercier, A., Robinson, M., Zhong, W., Ganem, D.E., Holdorf, M., Mapping of histone modifications in episomal HBV cccDNA uncovers an unusual chromatin organization amenable to epigenetic manipulation. Proc Natl Acad Sci U S A 112 (2015), E5715–E5724.
-
(2015)
Proc Natl Acad Sci U S A
, vol.112
, pp. E5715-E5724
-
-
Tropberger, P.1
Mercier, A.2
Robinson, M.3
Zhong, W.4
Ganem, D.E.5
Holdorf, M.6
-
36
-
-
78650807161
-
Hepatitis B virus resistance to antiviral drugs: where are we going?
-
[36] Zoulim, F., Hepatitis B virus resistance to antiviral drugs: where are we going?. Liver Int 31 (2011), 111–116.
-
(2011)
Liver Int
, vol.31
, pp. 111-116
-
-
Zoulim, F.1
-
37
-
-
0029838758
-
The hepatitis B virus persists for decades after patients’ recovery from acute viral hepatitis despite active maintenance of a cytotoxic T-lymphocyte response
-
[37] Rehermann, B., Ferrari, C., Pasquinelli, C., Chisari, F.V., The hepatitis B virus persists for decades after patients’ recovery from acute viral hepatitis despite active maintenance of a cytotoxic T-lymphocyte response. Nat Med 2 (1996), 1104–1108.
-
(1996)
Nat Med
, vol.2
, pp. 1104-1108
-
-
Rehermann, B.1
Ferrari, C.2
Pasquinelli, C.3
Chisari, F.V.4
-
38
-
-
84864378861
-
Identification of disubstituted sulfonamide compounds as specific inhibitors of hepatitis B virus covalently closed circular DNA formation
-
[38] Cai, D., Mills, C., Yu, W., Yan, R., Aldrich, C.E., Saputelli, J.R., et al. Identification of disubstituted sulfonamide compounds as specific inhibitors of hepatitis B virus covalently closed circular DNA formation. Antimicrob Agents Chemother 56 (2012), 4277–4288.
-
(2012)
Antimicrob Agents Chemother
, vol.56
, pp. 4277-4288
-
-
Cai, D.1
Mills, C.2
Yu, W.3
Yan, R.4
Aldrich, C.E.5
Saputelli, J.R.6
-
39
-
-
33748305988
-
Hepatitis B virus e antigen production is dependent upon covalently closed circular (ccc) DNA in HepAD38 cell cultures and may serve as a cccDNA surrogate in antiviral screening assays
-
[39] Zhou, T., Guo, H., Guo, J.T., Cuconati, A., Mehta, A., Block, T.M., Hepatitis B virus e antigen production is dependent upon covalently closed circular (ccc) DNA in HepAD38 cell cultures and may serve as a cccDNA surrogate in antiviral screening assays. Antiviral Res 72 (2006), 116–124.
-
(2006)
Antiviral Res
, vol.72
, pp. 116-124
-
-
Zhou, T.1
Guo, H.2
Guo, J.T.3
Cuconati, A.4
Mehta, A.5
Block, T.M.6
-
40
-
-
79957614798
-
Hepatitis B virus X protein is essential to initiate and maintain virus replication after infection
-
[40] Lucifora, J., Arzberger, S., Durantel, D., Belloni, L., Strubin, M., Levrero, M., et al. Hepatitis B virus X protein is essential to initiate and maintain virus replication after infection. J Hepatol 55 (2011), 996–1003.
-
(2011)
J Hepatol
, vol.55
, pp. 996-1003
-
-
Lucifora, J.1
Arzberger, S.2
Durantel, D.3
Belloni, L.4
Strubin, M.5
Levrero, M.6
-
41
-
-
77954226664
-
In vivo proliferation of hepadnavirus-infected hepatocytes induces loss of covalently closed circular DNA in mice
-
[41] Lutgehetmann, M., Volz, T., Kopke, A., Broja, T., Tigges, E., Lohse, A.W., et al. In vivo proliferation of hepadnavirus-infected hepatocytes induces loss of covalently closed circular DNA in mice. Hepatology 52 (2010), 16–24.
-
(2010)
Hepatology
, vol.52
, pp. 16-24
-
-
Lutgehetmann, M.1
Volz, T.2
Kopke, A.3
Broja, T.4
Tigges, E.5
Lohse, A.W.6
-
42
-
-
0037302268
-
Conditional replication of duck hepatitis B virus in hepatoma cells
-
[42] Guo, J.T., Pryce, M., Wang, X., Barrasa, M.I., Hu, J., Seeger, C., Conditional replication of duck hepatitis B virus in hepatoma cells. J Virol 77 (2003), 1885–1893.
-
(2003)
J Virol
, vol.77
, pp. 1885-1893
-
-
Guo, J.T.1
Pryce, M.2
Wang, X.3
Barrasa, M.I.4
Hu, J.5
Seeger, C.6
-
43
-
-
84884575067
-
Duck hepatitis B virus covalently closed circular DNA appears to survive hepatocyte mitosis in the growing liver
-
[43] Reaiche-Miller, G.Y., Thorpe, M., Low, H.C., Qiao, Q., Scougall, C.A., Mason, W.S., et al. Duck hepatitis B virus covalently closed circular DNA appears to survive hepatocyte mitosis in the growing liver. Virology 446 (2013), 357–364.
-
(2013)
Virology
, vol.446
, pp. 357-364
-
-
Reaiche-Miller, G.Y.1
Thorpe, M.2
Low, H.C.3
Qiao, Q.4
Scougall, C.A.5
Mason, W.S.6
-
44
-
-
0141593509
-
Hepatocyte turnover during resolution of a transient hepadnaviral infection
-
[44] Summers, J., Jilbert, A.R., Yang, W., Aldrich, C.E., Saputelli, J., Litwin, S., et al. Hepatocyte turnover during resolution of a transient hepadnaviral infection. Proc Natl Acad Sci U S A 100 (2003), 11652–11659.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 11652-11659
-
-
Summers, J.1
Jilbert, A.R.2
Yang, W.3
Aldrich, C.E.4
Saputelli, J.5
Litwin, S.6
-
45
-
-
84910029231
-
127 Proliferation of hepatitis B virus infected human hepatocytes induces suppression of viral replication and rapid cccDNA decrease in humanized mice
-
[45] Allweiss, L., Volz, T., Giersch, K., Lohse, A.W., Petersen, J., Lütgehetmann, M., et al. 127 Proliferation of hepatitis B virus infected human hepatocytes induces suppression of viral replication and rapid cccDNA decrease in humanized mice. J Hepatol 58 (2013), S56–S57.
-
(2013)
J Hepatol
, vol.58
, pp. S56-S57
-
-
Allweiss, L.1
Volz, T.2
Giersch, K.3
Lohse, A.W.4
Petersen, J.5
Lütgehetmann, M.6
-
46
-
-
77954489756
-
Control of hepatitis B virus at the level of transcription
-
[46] Quasdorff, M., Protzer, U., Control of hepatitis B virus at the level of transcription. J Viral Hepat 17 (2010), 527–536.
-
(2010)
J Viral Hepat
, vol.17
, pp. 527-536
-
-
Quasdorff, M.1
Protzer, U.2
-
47
-
-
45249096077
-
A concerted action of HNF4alpha and HNF1alpha links hepatitis B virus replication to hepatocyte differentiation
-
[47] Quasdorff, M., Hosel, M., Odenthal, M., Zedler, U., Bohne, F., Gripon, P., et al. A concerted action of HNF4alpha and HNF1alpha links hepatitis B virus replication to hepatocyte differentiation. Cell Microbiol 10 (2008), 1478–1490.
-
(2008)
Cell Microbiol
, vol.10
, pp. 1478-1490
-
-
Quasdorff, M.1
Hosel, M.2
Odenthal, M.3
Zedler, U.4
Bohne, F.5
Gripon, P.6
-
48
-
-
84957977888
-
IL6 inhibits HBV transcription by targeting the epigenetic control of the nuclear cccDNA minichromosome
-
[48] Palumbo, G.A., Scisciani, C., Pediconi, N., Lupacchini, L., Alfalate, D., Guerrieri, F., et al. IL6 inhibits HBV transcription by targeting the epigenetic control of the nuclear cccDNA minichromosome. PLoS One, 10, 2015, e0142599.
-
(2015)
PLoS One
, vol.10
, pp. e0142599
-
-
Palumbo, G.A.1
Scisciani, C.2
Pediconi, N.3
Lupacchini, L.4
Alfalate, D.5
Guerrieri, F.6
-
49
-
-
84945439538
-
HBx relieves chromatin-mediated transcriptional repression of hepatitis B viral cccDNA involving SETDB1 histone methyltransferase
-
[49] Riviere, L., Gerossier, L., Ducroux, A., Dion, S., Deng, Q., Michel, M.L., et al. HBx relieves chromatin-mediated transcriptional repression of hepatitis B viral cccDNA involving SETDB1 histone methyltransferase. J Hepatol 63 (2015), 1093–1102.
-
(2015)
J Hepatol
, vol.63
, pp. 1093-1102
-
-
Riviere, L.1
Gerossier, L.2
Ducroux, A.3
Dion, S.4
Deng, Q.5
Michel, M.L.6
-
50
-
-
84870522970
-
Hepatitis B virus X protein stimulates gene expression selectively from extrachromosomal DNA templates
-
[50] van Breugel, P.C., Robert, E.I., Mueller, H., Decorsiere, A., Zoulim, F., Hantz, O., et al. Hepatitis B virus X protein stimulates gene expression selectively from extrachromosomal DNA templates. Hepatology 56 (2012), 2116–2124.
-
(2012)
Hepatology
, vol.56
, pp. 2116-2124
-
-
van Breugel, P.C.1
Robert, E.I.2
Mueller, H.3
Decorsiere, A.4
Zoulim, F.5
Hantz, O.6
-
51
-
-
84907584690
-
The Tudor domain protein Spindlin1 is involved in intrinsic antiviral defense against incoming hepatitis B Virus and herpes simplex virus type 1
-
[51] Ducroux, A., Benhenda, S., Riviere, L., Semmes, O.J., Benkirane, M., Neuveut, C., The Tudor domain protein Spindlin1 is involved in intrinsic antiviral defense against incoming hepatitis B Virus and herpes simplex virus type 1. PLoS Pathog, 10, 2014, e1004343.
-
(2014)
PLoS Pathog
, vol.10
, pp. e1004343
-
-
Ducroux, A.1
Benhenda, S.2
Riviere, L.3
Semmes, O.J.4
Benkirane, M.5
Neuveut, C.6
-
52
-
-
79958761596
-
HBc binds to the CpG islands of HBV cccDNA and promotes an epigenetic permissive state
-
[52] Guo, Y.H., Li, Y.N., Zhao, J.R., Zhang, J., Yan, Z., HBc binds to the CpG islands of HBV cccDNA and promotes an epigenetic permissive state. Epigenetics 6 (2011), 720–726.
-
(2011)
Epigenetics
, vol.6
, pp. 720-726
-
-
Guo, Y.H.1
Li, Y.N.2
Zhao, J.R.3
Zhang, J.4
Yan, Z.5
-
53
-
-
73149094329
-
Not interferon, but interleukin-6 controls early gene expression in hepatitis B virus infection
-
[53] Hosel, M., Quasdorff, M., Wiegmann, K., Webb, D., Zedler, U., Broxtermann, M., et al. Not interferon, but interleukin-6 controls early gene expression in hepatitis B virus infection. Hepatology 50 (2009), 1773–1782.
-
(2009)
Hepatology
, vol.50
, pp. 1773-1782
-
-
Hosel, M.1
Quasdorff, M.2
Wiegmann, K.3
Webb, D.4
Zedler, U.5
Broxtermann, M.6
-
54
-
-
0032825042
-
Interferon gene transfer by a hepatitis B virus vector efficiently suppresses wild-type virus infection
-
[54] Protzer, U., Nassal, M., Chiang, P.W., Kirschfink, M., Schaller, H., Interferon gene transfer by a hepatitis B virus vector efficiently suppresses wild-type virus infection. Proc Natl Acad Sci U S A 96 (1999), 10818–10823.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 10818-10823
-
-
Protzer, U.1
Nassal, M.2
Chiang, P.W.3
Kirschfink, M.4
Schaller, H.5
-
55
-
-
84940460029
-
Mimicking Interferon-α (IFNα) inhibitory activity on hepatitis B virus (HBV) transcription and replication by targeting the epigenetic control of nuclear cccDNA minichromosome with epigenetic small molecules
-
[55] Belloni, L., Palumbo, G.A., Valente, S., Rotili, D., Pediconi, N., Mai, A., et al. Mimicking Interferon-α (IFNα) inhibitory activity on hepatitis B virus (HBV) transcription and replication by targeting the epigenetic control of nuclear cccDNA minichromosome with epigenetic small molecules. Hepatology, 56, 2012, 369A.
-
(2012)
Hepatology
, vol.56
, pp. 369A
-
-
Belloni, L.1
Palumbo, G.A.2
Valente, S.3
Rotili, D.4
Pediconi, N.5
Mai, A.6
-
56
-
-
84884692876
-
Alpha-interferon suppresses hepadnavirus transcription by altering epigenetic modification of cccDNA minichromosomes
-
[56] Liu, F., Campagna, M., Qi, Y., Zhao, X., Guo, F., Xu, C., et al. Alpha-interferon suppresses hepadnavirus transcription by altering epigenetic modification of cccDNA minichromosomes. PLoS Pathog, 9, 2013, e1003613.
-
(2013)
PLoS Pathog
, vol.9
, pp. e1003613
-
-
Liu, F.1
Campagna, M.2
Qi, Y.3
Zhao, X.4
Guo, F.5
Xu, C.6
-
57
-
-
77449113802
-
A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery
-
[57] Li, T., Robert, E.I., van Breugel, P.C., Strubin, M., Zheng, N., A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery. Nat Struct Mol Biol 17 (2010), 105–111.
-
(2010)
Nat Struct Mol Biol
, vol.17
, pp. 105-111
-
-
Li, T.1
Robert, E.I.2
van Breugel, P.C.3
Strubin, M.4
Zheng, N.5
-
58
-
-
84896029673
-
Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA
-
[58] Lucifora, J., Xia, Y., Reisinger, F., Zhang, K., Stadler, D., Cheng, X., et al. Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA. Science 343 (2014), 1221–1228.
-
(2014)
Science
, vol.343
, pp. 1221-1228
-
-
Lucifora, J.1
Xia, Y.2
Reisinger, F.3
Zhang, K.4
Stadler, D.5
Cheng, X.6
-
59
-
-
84952684286
-
Interferon-gamma and tumor necrosis factor-alpha produced by T cells reduce the HBV persistence form, cccDNA, without cytolysis
-
[59] Xia, Y., Stadler, D., Lucifora, J., Reisinger, F., Webb, D., Hosel, M., et al. Interferon-gamma and tumor necrosis factor-alpha produced by T cells reduce the HBV persistence form, cccDNA, without cytolysis. Gastroenterology 150 (2016), 194–205.
-
(2016)
Gastroenterology
, vol.150
, pp. 194-205
-
-
Xia, Y.1
Stadler, D.2
Lucifora, J.3
Reisinger, F.4
Webb, D.5
Hosel, M.6
-
60
-
-
37349056697
-
T cells redirected against hepatitis B virus surface proteins eliminate infected hepatocytes
-
[60] Bohne, F., Chmielewski, M., Ebert, G., Wiegmann, K., Kurschner, T., Schulze, A., et al. T cells redirected against hepatitis B virus surface proteins eliminate infected hepatocytes. Gastroenterology 134 (2008), 239–247.
-
(2008)
Gastroenterology
, vol.134
, pp. 239-247
-
-
Bohne, F.1
Chmielewski, M.2
Ebert, G.3
Wiegmann, K.4
Kurschner, T.5
Schulze, A.6
-
61
-
-
84880582625
-
T cells expressing a chimeric antigen receptor that binds hepatitis B virus envelop proteins control virus replication in mice
-
[61] Krebs, K., Bottinger, N., Huang, L.R., Chmielewski, M., Arzberger, S., Gasteiger, G., et al. T cells expressing a chimeric antigen receptor that binds hepatitis B virus envelop proteins control virus replication in mice. Gastroenterology 145 (2013), 456–465.
-
(2013)
Gastroenterology
, vol.145
, pp. 456-465
-
-
Krebs, K.1
Bottinger, N.2
Huang, L.R.3
Chmielewski, M.4
Arzberger, S.5
Gasteiger, G.6
-
62
-
-
85000432888
-
HAPs hepatitis B virus (HBV) capsid inhibitors block core protein interaction with the viral minichromosome and host cell genes and affect cccDNA transcription and stability
-
[62] Belloni, L., Li, L., Palumbo, G.A., Chirapu, S.R., Calvo, L., Finn, M.G., et al. HAPs hepatitis B virus (HBV) capsid inhibitors block core protein interaction with the viral minichromosome and host cell genes and affect cccDNA transcription and stability. Hepatology, 54, 2013, 277A.
-
(2013)
Hepatology
, vol.54
, pp. 277A
-
-
Belloni, L.1
Li, L.2
Palumbo, G.A.3
Chirapu, S.R.4
Calvo, L.5
Finn, M.G.6
-
63
-
-
77952011493
-
Zinc-finger nucleases as a novel therapeutic strategy for targeting hepatitis B virus DNAs
-
[63] Cradick, T.J., Keck, K., Bradshaw, S., Jamieson, A.C., McCaffrey, A.P., Zinc-finger nucleases as a novel therapeutic strategy for targeting hepatitis B virus DNAs. Mol Ther 18 (2010), 947–954.
-
(2010)
Mol Ther
, vol.18
, pp. 947-954
-
-
Cradick, T.J.1
Keck, K.2
Bradshaw, S.3
Jamieson, A.C.4
McCaffrey, A.P.5
-
64
-
-
84880799657
-
Predictors of hepatitis B cure using gene therapy to deliver DNA cleavage enzymes: a mathematical modeling approach
-
[64] Schiffer, J.T., Swan, D.A., Stone, D., Jerome, K.R., Predictors of hepatitis B cure using gene therapy to deliver DNA cleavage enzymes: a mathematical modeling approach. PLoS Comput Biol, 9, 2013, e1003131.
-
(2013)
PLoS Comput Biol
, vol.9
, pp. e1003131
-
-
Schiffer, J.T.1
Swan, D.A.2
Stone, D.3
Jerome, K.R.4
-
65
-
-
84895908706
-
An efficient antiviral strategy for targeting hepatitis B virus genome using transcription activator-like effector nucleases
-
[65] Chen, J., Zhang, W., Lin, J., Wang, F., Wu, M., Chen, C., et al. An efficient antiviral strategy for targeting hepatitis B virus genome using transcription activator-like effector nucleases. Mol Ther 22 (2014), 303–311.
-
(2014)
Mol Ther
, vol.22
, pp. 303-311
-
-
Chen, J.1
Zhang, W.2
Lin, J.3
Wang, F.4
Wu, M.5
Chen, C.6
-
66
-
-
84885023096
-
Inactivation of hepatitis B virus replication in cultured cells and in vivo with engineered transcription activator-like effector nucleases
-
[66] Bloom, K., Ely, A., Mussolino, C., Cathomen, T., Arbuthnot, P., Inactivation of hepatitis B virus replication in cultured cells and in vivo with engineered transcription activator-like effector nucleases. Mol Ther 21 (2013), 1889–1897.
-
(2013)
Mol Ther
, vol.21
, pp. 1889-1897
-
-
Bloom, K.1
Ely, A.2
Mussolino, C.3
Cathomen, T.4
Arbuthnot, P.5
-
67
-
-
84927935415
-
Targeting hepatitis B virus with CRISPR/Cas9
-
[67] Seeger, C., Sohn, J.A., Targeting hepatitis B virus with CRISPR/Cas9. Mol Ther Nucleic Acids, 3, 2014, e216.
-
(2014)
Mol Ther Nucleic Acids
, vol.3
, pp. e216
-
-
Seeger, C.1
Sohn, J.A.2
-
68
-
-
84920095727
-
Suppression of hepatitis B virus DNA accumulation in chronically infected cells using a bacterial CRISPR/Cas RNA-guided DNA endonuclease
-
[68] Kennedy, E.M., Bassit, L.C., Mueller, H., Kornepati, A.V., Bogerd, H.P., Nie, T., et al. Suppression of hepatitis B virus DNA accumulation in chronically infected cells using a bacterial CRISPR/Cas RNA-guided DNA endonuclease. Virology 476 (2015), 196–205.
-
(2015)
Virology
, vol.476
, pp. 196-205
-
-
Kennedy, E.M.1
Bassit, L.C.2
Mueller, H.3
Kornepati, A.V.4
Bogerd, H.P.5
Nie, T.6
-
69
-
-
84927513847
-
Targeting hepatitis B virus cccDNA by CRISPR/Cas9 nuclease efficiently inhibits viral replication
-
[69] Dong, C., Qu, L., Wang, H., Wei, L., Dong, Y., Xiong, S., Targeting hepatitis B virus cccDNA by CRISPR/Cas9 nuclease efficiently inhibits viral replication. Antiviral Res 118 (2015), 110–117.
-
(2015)
Antiviral Res
, vol.118
, pp. 110-117
-
-
Dong, C.1
Qu, L.2
Wang, H.3
Wei, L.4
Dong, Y.5
Xiong, S.6
-
70
-
-
85010908060
-
Experimental in vitro and in vivo models for the study of human hepatitis B virus infection
-
[70] Allweis, L., Dandri, M., Experimental in vitro and in vivo models for the study of human hepatitis B virus infection. J Hepatol 64 (2016), S17–S31.
-
(2016)
J Hepatol
, vol.64
, pp. S17-S31
-
-
Allweis, L.1
Dandri, M.2
-
71
-
-
85010842062
-
New antiviral targets for innovative treatment concepts for hepatitis B virus and hepatitis delta virus
-
[71] Durantel, D., Zoulim, F., New antiviral targets for innovative treatment concepts for hepatitis B virus and hepatitis delta virus. J Hepatol 64 (2016), S117–S131.
-
(2016)
J Hepatol
, vol.64
, pp. S117-S131
-
-
Durantel, D.1
Zoulim, F.2
|