Enhanced predictive signalling in schizophrenia

Human Brain Mapping

Volumn 38, Issue 4, 2017, Pages 1767-1779

  Schmack, Katharina ^a,b   Rothkirch, Marcus ^a   Priller, Josef ^a,b,c   Sterzer, Philipp ^a,d  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b BERLIN INSTITUTE OF HEALTH   (Germany)

^c GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^d HUMBOLDT UNIVERSITY   (Germany)

Author keywords

Delusions; Functional magnetic resonance imaging; Hallucinations; Placebo effect; Predictive coding; Psychosis; Schizophrenia; Visual perception

Indexed keywords

ADULT; ARTICLE; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DEPTH PERCEPTION; DISEASE ASSOCIATION; DSM-IV; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HALLUCINATION; HUMAN; ICD-10; MALE; NEUROIMAGING; ORBITAL CORTEX; POSITIVE AND NEGATIVE SYNDROME SCALE; POSITIVE SYNDROME; PRIORITY JOURNAL; SCHIZOPHRENIA; SIGNAL TRANSDUCTION; STEREOSCOPIC VISION; STRUCTURED CLINICAL INTERVIEW FOR DSM DISORDERS; BLOOD; BRAIN; CASE CONTROL STUDY; CULTURAL ANTHROPOLOGY; DIAGNOSTIC IMAGING; HEMISPHERIC DOMINANCE; IMAGE PROCESSING; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; PERCEPTIVE DISCRIMINATION; PHOTOSTIMULATION; PHYSIOLOGY; PSYCHOLOGY; SENSORY NERVE; VISION;

OXYGEN;

ADULT; AFFERENT PATHWAYS; BRAIN; CASE-CONTROL STUDIES; CULTURE; FEMALE; FUNCTIONAL LATERALITY; HALLUCINATIONS; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; OXYGEN; PHOTIC STIMULATION; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY; SIGNAL DETECTION, PSYCHOLOGICAL; VISUAL PERCEPTION;

EID: 85010818895     PISSN: 10659471     EISSN: 10970193     Source Type: Journal    
DOI: 10.1002/hbm.23480     Document Type: Article

References (34)

1. Adams RA, Stephan KE, Brown HR, Frith CD, Friston KJ (2013): The computational anatomy of psychosis. Front Psychiatry 4: 47.
2. Bar M, Kassam KS, Ghuman AS, Boshyan J, Schmid AM, Schmidt AM, Dale AM, Hämäläinen MS, Marinkovic K, Schacter DL, Rosen BR, Halgren E (2006): Top-down facilitation of visual recognition. Proc Natl Acad Sci U S A 103:449–454.
3. Corlett PR, Frith CD, Fletcher PC (2009): From drugs to deprivation: A Bayesian framework for understanding models of psychosis. Psychopharmacology (Berl) 206:515–530.
4. Corlett PR, Taylor JR, Wang X-J, Fletcher PC, Krystal JH (2010): Toward a neurobiology of delusions. Prog Neurobiol 92: 345–369.
5. Dakin S, Carlin P, Hemsley D (2005): Weak suppression of visual context in chronic schizophrenia. Curr Biol CB 15:R822–R824.
6. Deserno L, Boehme R, Heinz A, Schlagenhauf F (2013): Reinforcement learning and dopamine in schizophrenia: Dimensions of symptoms or specific features of a disease group?. Front Psychiatry 4:172.
7. Dima D, Roiser JP, Dietrich DE, Bonnemann C, Lanfermann H, Emrich HM, Dillo W (2009): Understanding why patients with schizophrenia do not perceive the hollow-mask illusion using dynamic causal modelling. NeuroImage 46:1180–1186.
8. First MB, Spitzer RL, Gibbon M, Williams JB (2002a): Structured Clinical Interview for DSM-IV-TR Axis I Disorders, Research Version, Patient Edition. (SCID-I/P). N Y Biom Res N Y State Psychiatr Inst.
9. First MB, Spitzer RL, Gibbon M, Williams JB (2002b): Structured Clinical Interview for DSM-IV-TR Axis I Disorders, Research Version, Non-patient Edition. (SCID-I/NP). N Y Biom Res N Y State Psychiatr Inst.
10. Fletcher PC, Frith CD (2009): Perceiving is believing: A Bayesian approach to explaining the positive symptoms of schizophrenia. Nat Rev Neurosci 10:48–58.
11. Friston K (2005): A theory of cortical responses. Philos Trans R Soc Lond B Biol Sci 360:815–836.
12. Friston KJ, Buechel C, Fink GR, Morris J, Rolls E, Dolan RJ (1997): Psychophysiological and modulatory interactions in neuroimaging. NeuroImage 6:218–229.
13. Gitelman DR, Penny WD, Ashburner J, Friston KJ (2003): Modeling regional and psychophysiologic interactions in fMRI: The importance of hemodynamic deconvolution. NeuroImage 19: 200–207.
14. Heinz A (2002): Dopaminergic dysfunction in alcoholism and schizophrenia–psychopathological and behavioral correlates. Eur Psychiatry J Assoc Eur Psychiatr 17:9–16.
15. Hemsley DR (2005): The schizophrenic experience: Taken out of context?. Schizophr Bull 31:43–53.
16. Kapur S (2003): Psychosis as a state of aberrant salience: A framework linking biology, phenomenology, and pharmacology in schizophrenia. Am J Psychiatry 160:13–23.
17. Kersten D, Mamassian P, Yuille A (2004): Object perception as Bayesian inference. Annu Rev Psychol 55:271–304.
18. Leucht S, Samara M, Heres S, Davis JM (2016): Dose equivalents for antipsychotic drugs: The DDD method. Schizophr Bull 42 Suppl 1:S90–S94.
19. Manoach DS, Press DZ, Thangaraj V, Searl MM, Goff DC, Halpern E, Saper CB, Warach S (1999): Schizophrenic subjects activate dorsolateral prefrontal cortex during a working memory task, as measured by fMRI. Biol Psychiatry 45:1128–1137.
20. Mumford D (1992): On the computational architecture of the neocortex. II. The role of cortico-cortical loops. Biol Cybern 66: 241–251.
21. Notredame C-E, Pins D, Deneve S, Jardri R (2014): What visual illusions teach us about schizophrenia. Front Integr Neurosci 8:63.
22. Petrovic P, Kalso E, Petersson KM, Ingvar M (2002): Placebo and opioid analgesia–imaging a shared neuronal network. Science 295:1737–1740.
23. Powers AR, III Kelley M, Corlett PR (2016): Hallucinations as Top-Down Effects on Perception. Biol Psychiatry Cogn Neurosci Neuroimaging 1:393–400.
24. Sanders LLO, Muckli L, de Millas W, Lautenschlager M, Heinz A, Kathmann N, Sterzer P (2012): Detection of visual events along the apparent motion trace in patients with paranoid schizophrenia. Psychiatry Res 198:216–223.
25. Schmack K, Gómez-Carrillo de Castro A, Rothkirch M, Sekutowicz M, Rössler H, Haynes J-D, Heinz A, Petrovic P, Sterzer P (2013): Delusions and the role of beliefs in perceptual inference. J Neurosci Off J Soc Neurosci 33:13701–13712.
26. Schmack K, Schnack A, Priller J, Sterzer P (2015): Perceptual instability in schizophrenia: Probing predictive coding accounts of delusions with ambiguous stimuli. Schizophr Res Cogn 2:72–77.
27. Schneider U, Borsutzky M, Seifert J, Leweke FM, Huber TJ, Rollnik JD, Emrich HM (2002): Reduced binocular depth inversion in schizophrenic patients. Schizophr Res 53:101–108.
28. Schurger A (2009): A very inexpensive MRI-compatible method for dichoptic visual stimulation. J Neurosci Methods 177:199–202.
29. Seymour K, Stein T, Sanders LLO, Guggenmos M, Theophil I, Sterzer P (2013): Altered contextual modulation of primary visual cortex responses in schizophrenia. Neuropsychopharmacol Off Publ Am Coll Neuropsychopharmacol 38:2607–2612.
30. Steinberg EE, Keiflin R, Boivin JR, Witten IB, Deisseroth K, Janak PH (2013): A causal link between prediction errors, dopamine neurons and learning. Nat Neurosci 16:966–973.
31. Sterzer P, Frith C, Petrovic P (2008): Believing is seeing: Expectations alter visual awareness. Curr Biol CB 18:R697–R698.
32. Summerfield C, Koechlin E (2008): A neural representation of prior information during perceptual inference. Neuron 59: 336–347.
33. Teufel C, Subramaniam N, Dobler V, Perez J, Finnemann J, Mehta PR, Goodyer IM, Fletcher PC (2015): Shift toward prior knowledge confers a perceptual advantage in early psychosis and psychosis-prone healthy individuals. Proc Natl Acad Sci U S A 112:13401–13406.
34. Uhlhaas PJ, Silverstein SM, Phillips WA, Lovell PG (2004): Evidence for impaired visual context processing in schizotypy with thought disorder. Schizophr Res 68:249–260.