Recruited monocytic myeloid-derived suppressor cells promote the arrest of tumor cells in the premetastatic niche through an IL-1β-mediated increase in E-selectin expression

International Journal of Cancer

Volumn 140, Issue 6, 2017, Pages 1370-1383

  Shi, Huifang ^a   Zhang, Juechao ^a   Han, Xiaoqing ^a   Li, Huihan ^a   Xie, Mingshu ^a   Sun, Yingying ^a   Liu, Wenguang ^a   Ba, Xueqing ^a   Zeng, Xianlu ^a  

^a NORTHEAST NORMAL UNIVERSITY   (China)

Author keywords

E selectin; IL 1 ; mo MDSCs; premetastatic niche; tumor cell arrest

Indexed keywords

ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; INTERLEUKIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 5; CCL12 PROTEIN, MOUSE; MONOCYTE CHEMOTACTIC PROTEIN; TUMOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ADHESION; CELL MIGRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DISTANT METASTASIS; ENDOTHELIUM CELL; GENE EXPRESSION; INTERSTITIAL MACROPHAGE; LUNG ALVEOLUS MACROPHAGE; LUNG METASTASIS; MELANOMA; MOUSE; MYELOID-DERIVED SUPPRESSOR CELL; NONHUMAN; TUMOR MICROENVIRONMENT; ANIMAL; ANTIBODY SPECIFICITY; BIOSYNTHESIS; C57BL MOUSE; CELL MOTION; CLASSIFICATION; COCULTURE; EXPERIMENTAL MELANOMA; GENE EXPRESSION REGULATION; GENE SILENCING; GENETICS; IMMUNOLOGY; LUNG TUMOR; MACROPHAGE; METABOLISM; MONOCYTE; PATHOLOGY; PHYSIOLOGY; SECONDARY; STEM CELL NICHE; TUMOR CELL CULTURE; TUMOR EMBOLISM; VASCULAR ENDOTHELIUM;

ANIMALS; CELL ADHESION; CELL MOVEMENT; COCULTURE TECHNIQUES; E-SELECTIN; ENDOTHELIUM, VASCULAR; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; INTERLEUKIN-1BETA; LUNG NEOPLASMS; MACROPHAGES; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; MONOCYTE CHEMOATTRACTANT PROTEINS; MONOCYTES; MYELOID-DERIVED SUPPRESSOR CELLS; NEOPLASM PROTEINS; NEOPLASTIC CELLS, CIRCULATING; ORGAN SPECIFICITY; STEM CELL NICHE; TUMOR CELLS, CULTURED; TUMOR MICROENVIRONMENT;

EID: 85010750301     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.30538     Document Type: Article

References (50)

1. Woodhouse EC, Chuaqui RF, Liotta LA. General mechanisms of metastasis. Cancer 1997;80:1529–37.
2. Minn AJ, Gupta GP, Siegel PM, et al. Genes that mediate breast cancer metastasis to lung. Nature 2005;436:518–24.
3. Bethan P, David L. The metastatic niche: adapting the foreign soil. Nat Rev Cancer 2009;9:285–93.
4. Kaplan RN, Shahin R, David L. Preparing the ''soil'': the premetastatic niche. Cancer Res 2007;66:11089–93.
5. Sceneay J, Smyth MJ, Möller A. The pre-metastatic niche: finding common ground. Cancer Metast Rev 2013;32:449–64.
6. Gao D, Joshi N, Choi H, et al. Myeloid progenitor cells in the premetastatic lung promote metastases by inducing mesenchymal to epithelial transition. Cancer Res 2012;72:1384–94.
7. Lee E, Fertig EJ, Jin K, et al. Breast cancer cells condition lymphatic endothelial cells within pre-metastatic niches to promote metastasis. Nat Commun 2014;5:4715–30.
8. + granulocytes. Proc Natl Acad Sci USA 2010;107:21248–55.
9. Kaplan RN, Riba RD, Zacharoulis S, et al. VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature 2005;438:820–27.
10. Hiratsuka S, Watanabe A, Sakurai Y, et al. The S100A8–serum amyloid A3–TLR4 paracrine cascade establishes a pre-metastatic phase. Nat Cell Biol 2008;10:1349–55.
11. Mammoto A, Mammoto T, Kanapathipillai M, et al. Control of lung vascular permeability and endotoxin-induced pulmonary oedema by changes in extracellular matrix mechanics. Nat Commun 2013;4:1759–68.
12. Hiratsuka S, Watanabe A, Aburatani H, et al. Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis. Nat Cell Biol 2006;8:1369–75.
13. Joyce JA, Pollard JW. Microenvironmental regulation of metastasis. Nat Rev Cancer 2009;9:239–52.
14. Gabrilovich DI, Nagaraj S. Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev 2009;9:162–74.
15. Serafini P, Santo CD, Marigo I, et al. Derangement of immune responses by myeloid suppressor cells. Cancer Immunol Immun 2004;53:64–72.
16. Raber PL, Paul T, Rosa S, et al. Subpopulations of myeloid-derived suppressor cells impair T cell responses through independent nitric oxide-related pathways. Int J Cancer 2014;134:2853–64.
17. Talmadge JE, Gabrilovich DI. History of myeloid-derived suppressor cells. Nat Rev 2013;13:739–52.
18. Nolan DJ, Ciarrocchi A, Mellick AS, et al. Bone marrow-derived endothelial progenitor cells are a major determinant of nascent tumor neovascularization. Gene Dev 2007;21:1546–58.
19. Davidoff AM, Ng CY, Brown P, et al. Bone marrow-derived cells contribute to tumor neovasculature and, when modified to express an angiogenesis inhibitor, can restrict tumor growth in mice. Clin Cancer Res 2001;7:2870–79.
20. Youn JI, Nagaraj S, Collazo M, et al. Subsets of myeloid-derived suppressor cells in tumor-bearing mice. J Immunol 2008;181:5791–802.
21. Rodriguez PC, Ernstoff MS, Claudia H, et al. Arginase I–producing myeloid-derived suppressor cells in renal cell carcinoma are a subpopulation of activated granulocytes. Cancer Res 2009;69:1553–60.
22. + myeloid-derived suppressor cell expansion in cancer patients. J Immunol 2009;182:6562–68.
23. + myeloid cells tip the balance of immune protection to tumor promotion in the premetastatic lung. Cancer Res 2010;70:6139–49.
24. Acuff HB, Carter KJ, Fingleton B, et al. Matrix metalloproteinase-9 from bone marrow-derived cells contributes to survival but not growth of tumor cells in the lung microenvironment. Cancer Res 2006;66:259–66.
25. + immune suppressor cells and compromises NK cell cytotoxicity in the premetastatic niche. Cancer Res 2012;72:3906–11.
26. Vincent H, Benjamin JD, Lishi S, et al. Mitigating age-related immune dysfunction heightens the efficacy of tumor immunotherapy in aged mice. Cancer Res 2012;72:2089–99.
27. Gabrilovich DI, Ostrand-Rosenberg S, Bronte V. Coordinated regulation of myeloid cells by tumours. Nat Rev 2012;12:253–68.
28. Stackpole CW. Distinct lung-colonizing and lung-metastasizing cell populations in B16 mouse melanoma. Nature 1981;289:798–800.
29. Grivennikov SI, Greten FR, Karin M. Immunity, inflammation, and cancer. Cell 2010;140:883–99.
30. Nguyen DX, Bos PD, Massagué J. Metastasis: from dissemination to organ-specific colonization. Nat Rev 2009;9:274–84.
31. Labelle M, Hynes RO. The initial hours of metastasis: the importance of cooperative host-tumor cell interactions during hematogenous dissemination. Cancer Discov 2012;2:1091–99.
32. Richter U, Schröder C, Wicklein D, et al. Adhesion of small cell lung cancer cells to E- and P-Selectin under physiological flow conditions: implications for metastasis formation. Histochem Cell Biol 2011;135:499–512.
33. Stübkea K, Wickleina D, Herich L, et al. Selectin-deficiency reduces the number of spontaneous metastases in a xenograft model of human breast cancer. Cancer Lett 2012;321:89–99.
34. Huang Y, Song N, Ding Y, et al. Pulmonary vascular destabilization in the premetastatic phase facilitates lung metastasis. Cancer Res 2009;69:7529–37.
35. Leeuwenberg JF, Smeets EF, Neefjes JJ, et al. E-selectin and intercellular adhesion molecule-1 are released by activated human endothelial cells in vitro. Immunology 1992;77:543–9.
36. Wyble CW, Hynes KL, Kuchibhotla J, et al. TNF-β and IL-1 upregulate membrane-bound and soluble E-selectin through a common pathway. J Surg Res 1997;73:107–12.
37. Mayer-Barber KD, Andrade BB, Barber DL, et al. Innate and adaptive interferons suppress IL-1alpha and IL-1beta production by distinct pulmonary myeloid subsets during Mycobacterium tuberculosis infection. Immunity 2011;35:1023–34.
38. Sharma SK, Chintala NK, Vadrevu SK, et al. Pulmonary alveolar macrophages contribute to the premetastatic niche by suppressing antitumor T cell responses in the lungs. J Immunol 2015;194:5529–38.
39. Lu T, Gabrilovich DI. Molecular pathways: tumor-infiltrating myeloid cells and reactive oxygen species in regulation of tumor microenvironment. Clin Cancer Res 2012;18:4877–82.
40. + cells in tumor-bearing host directly promotes tumor angiogenesis. Cancer Cell 2004;6:271–71.
41. Du R, Lu KV, Petritsch C, et al. HIF1alpha induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion. Cancer Cell 2008;13:206–20.
42. + myeloid cells that promote metastasis. Cancer Cell 2008;13:23–35.
43. Barthel SR, Gavino JD, Descheny L, et al. Targeting selectins and selectin ligands in inflammation and cancer. Expert Opin Ther Target 2007;11:1473–91.
44. Biancone L, Araki M, Araki K, et al. Redirection of tumor metastasis by expression of E-selectin in vivo. J Exp Med 1996;183:581–7.
45. Hiratsuka S, Goel S, Kamoun WS, et al. Endothelial focal adhesion kinase mediates cancer cell homing to discrete regions of the lungs via e-selectin up-regulation. Proc Natl Acad Sci USA 2011;108:3725–30.
46. Eran E, Roni N, Thaiss CA, et al. Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganisms. Nat Rev Cancer 2013;13:759–71.
47. Alberto M, Paola A, Antonio S, et al. Cancer-related inflammation. Nature 2008;454:436–44.
48. Balkwill F. TNF-alpha in promotion and progression of cancer. Cancer Metast Rev 2006;25:409–16.
49. Tu S, Bhagat G, Cui G, et al. Overexpression of Interleukin-1β induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice. Cancer Cell 2008;14:408–19.
50. Zhao H, Kalish F, Schulz S, et al. Unique roles of infiltrating myeloid cells in the murine uterus during early to midpregnancy. J Immunol 2015;194:3713–22.