Excess mortality in persons with severe mental disorders: a multilevel intervention framework and priorities for clinical practice, policy and research agendas

World Psychiatry

Volumn 16, Issue 1, 2017, Pages 30-40

  Liu, Nancy H ^a,b   Daumit, Gail L ^c   Dua, Tarun ^a   Aquila, Ralph ^d   Charlson, Fiona ^e   Cuijpers, Pim ^f   Druss, Benjamin ^g   Dudek, Kenn ^d   Freeman, Melvyn ^h   Fujii, Chiyo ⁱ   Gaebel, Wolfgang ^j   Hegerl, Ulrich ^k   Levav, Itzhak ^l   Munk Laursen, Thomas ^m   Ma, Hong ⁿ   Maj, Mario ^o   Elena Medina Mora, Maria ^p   Nordentoft, Merete ^q   Prabhakaran, Dorairaj ^r   Pratt, Karen ^d   Prince, Martin ^s   Rangaswamy, Thara ^t   Shiers, David ^u   Susser, Ezra ^v   Thornicroft, Graham ^s   Wahlbeck, Kristian ^w   Fekadu Wassie, Abe ^x   Whiteford, Harvey ^e   Saxena, Shekhar ^a   more..

^a WORLD HEALTH ORGANIZATION   (Switzerland)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c DEPARTMENT OF PATHOLOGY   (United States)

^d Fountain House   (United States)

^e Queensland Centre for Mental Health Research   (Australia)

^f VU UNIVERSITY AMSTERDAM   (Netherlands)

^g EMORY UNIVERSITY   (United States)

^h National Department of Health   (South Africa)

ⁱ NATIONAL INSTITUTE OF MENTAL HEALTH   (Japan)

^j HEINRICH HEINE UNIVERSITY   (Germany)

^k UNIVERSITY HOSPITAL LEIPZIG   (Germany)

^l UNIVERSITY OF HAIFA   (Israel)

^m AARHUS UNIVERSITY   (Denmark)

ⁿ Institute of Mental Health   (China)

^o SECOND UNIVERSITY OF NAPLES   (Italy)

^p INSTITUTO NACIONAL DE PSIQUIATRÍA RAMÓN DE LA FUENTE MUÑIZ   (Mexico)

^q UNIVERSITY OF COPENHAGEN   (Denmark)

^r PUBLIC HEALTH FOUNDATION OF INDIA   (India)

^s KING'S COLLEGE LONDON   (United Kingdom)

^t SCHIZOPHRENIA RESEARCH FOUNDATION   (India)

^u Healthy Active Lives   (United Kingdom)

^v Och Spine at New York Presbyterian Hospitals   (United States)

^w Psychotherapy Clinic   (Finland)

^x ADDIS ABABA UNIVERSITY   (Ethiopia)

more..

Author keywords

bipolar disorder; community level and policy focused interventions; depression; Excess mortality; health system focused interventions; individual focused interventions; physical health; risk factors; schizophrenia; severe mental disorders

Indexed keywords

ARTICLE; CLINICAL PRACTICE; COMMUNITY LEVEL AND POLICY FOCUSED FRAMEWORK; CONCEPTUAL FRAMEWORK; DISEASE SEVERITY; HEALTH CARE DELIVERY; HEALTH CARE POLICY; HEALTH PROGRAM; HEALTH SYSTEM FOCUSED FRAMEWORK; HUMAN; INDIVIDUAL FOCUSED FRAMEWORK; LIFESTYLE; MENTAL DISEASE; METABOLIC MONITORING PROGRAM; MODEL; MORTALITY; NURSE PRACTITIONER; PEER SUPPORT PROGRAM; PRACTICE GUIDELINE; RESEARCH; RISK FACTOR; STIGMA REDUCTION PROGRAM; SUPPORT GROUP;

EID: 85010703254     PISSN: 17238617     EISSN: 20515545     Source Type: Journal    
DOI: 10.1002/wps.20384     Document Type: Article

References (96)

1. Wahlbeck K, Westman J, Nordentoft M et al. Outcome of Nordic mental health systems: life expectancy of patients with mental disorders in Denmark, Finland and Sweden 1987-2006. Br J Psychiatry 2011;199:453-8.
2. Chesney E, Goodwin GM, Fazel S. Risks of all-cause and suicide mortality in mental disorders: a meta-review. World Psychiatry 2014;13:153-60.
3. Laursen TM, Musliner KL, Benros ME et al. Mortality and life expectancy in persons with severe unipolar depression. J Affect Disord 2016;193:203-7.
4. Saha S, Chant D, McGrath J. A systematic review of mortality in schizophrenia. Arch Gen Psychiatry 2007;64:1123-31.
5. Cuijpers P, Vogelzangs N, Twisk J et al. Comprehensive meta-analysis of excess mortality in depression in the general community versus patients with specific illnesses. Am J Psychiatry 2014;171:453-62.
6. Walker ER, McGee RE, Druss BG. Mortality in mental disorders and global disease burden implications: a systematic review and meta-analysis. JAMA Psychiatry 2015;72:334-41.
7. Hayes JF, Miles J, Walters K et al. A systematic review and meta-analysis of premature mortality in bipolar affective disorder. Acta Psychiatr Scand 2015;131:417-25.
8. Maj M. Physical illness and access to medical services in persons with schizophrenia. Int J Ment Health 2008;37:3-21.
9. Thornicroft G. Physical health disparities and mental illness: the scandal of premature mortality. Br J Psychiatry 2011;100:441-2.
10. De Hert M, Cohen D, Bobes J et al. Physical illness in patients with severe mental disorders. II. Barriers to care, monitoring and treatment guidelines, plus recommendations at the system and individual level. World Psychiatry 2011;10:138-51.
11. Suetani S, Whiteford HA, McGrath JJ. An urgent call to address the deadly consequences of serious mental disorders. JAMA Psychiatry 2015;72:1166-7.
12. Charlson FJ, Baxter AJ, Dua L et al. Excess mortality from mental, neurological and substance use disorders in the Global Burden of Disease Study 2010. Epidemiol Psychiatr Sci 2015;24:121-40.
13. Olfson M, Gerhard T, Huang C et al. Premature mortality among adults with schizophrenia in the United States. JAMA Psychiatry 2015;72:1172-81.
14. Laursen TM. Life expectancy among persons with schizophrenia or bipolar affective disorder. Schizophr Res 2011;131:101-4.
15. Crump C, Winkleby MA, Sundquist K et al. Comorbidities and mortality in persons with schizophrenia: a Swedish national cohort study. Am J Psychiatry 2013;170:324-33.
16. Fekadu A, Medhin G, Kebede D et al. Excess mortality in severe mental illness: 10-year population-based cohort study in rural Ethiopia. Br J Psychiatry 2015;206:289-96.
17. Laursen TM, Mortensen PB, MacCabe JH et al. Cardiovascular drug use and mortality in patients with schizophrenia or bipolar disorder. A Danish population-based study. Psychol Med 2013;12:1-13.
18. Nordentoft M, Wahlbeck K, Hallgren J et al. Excess mortality and causes of death and life expectancy in 270,770 patients with recent onset of mental disorders in Denmark, Finland and Sweden. PLoS One 2013;8:e55176.
19. Hennekens CH, Hennekens AR, Hollar D et al. Schizophrenia and increased risks of cardiovascular disease. Am Heart J 2005;150:1115-21.
20. Crump C, Sundquist K, Winkleby MA et al. Comorbidities and mortality in bipolar disorder: a Swedish national cohort study. JAMA Psychiatry 2013;70:931-9.
21. Lawrence D, Holman CD, Jablensky AV et al. Excess cancer mortality in Western Australian psychiatric patients due to higher case fatality rates. Acta Psychiatr Scand 2000;101:382-8.
22. Nordentoft M, Mortensen PB, Pederson CB. Absolute risk of suicide after first hospital contact in mental disorder. Arch Gen Psychiatry 2011;68:1058-64.
23. Crump C, Sundquist K, Winkleby MA et al. Mental disorders and risk of accidental death. Br J Psychiatry 2013;203:297-302.
24. Crump C, Sundquist K, Winkleby MA et al. Mental disorders and vulnerability to homicidal death: Swedish nationwide cohort study. BMJ 2013;346:f557.
25. World Health Organization. A conceptual framework for action on social determinants of health. Geneva: World Health Organization, 2010.
26. Marmot M, Friel S, Bell R et al. Closing the gap in a generation: health equity through action on the social determinants of health. Lancet 2008;372:1661-9.
27. World Health Organization. Mental health action plan 2013-2020. Geneva: World Health Organization, 2013.
28. Lasser K, Boyd JW, Woolhandler S et al. Smoking and mental illness: a population-based prevalence study. JAMA 2000;284:2606-10.
29. Dipasquale S, Pariante CM, Dazzan P et al. The dietary pattern of patients with schizophrenia: a systematic review. J Psychiatry Res 2013;47:197-207.
30. Janney CA, Ganguli R, Richardson CR et al. Sedentary behaviour and psychiatric symptoms in overweight and obese adults with schizophrenia and schizoaffective disorders (WAIST study). Schizophr Res 2013;145:63-8.
31. Correll CU, Detraux J, De Lepeleire J et al. Effects of antipsychotics, antidepressants and mood stabilizers on risk for physical diseases in people with schizophrenia, depression and bipolar disorder. World Psychiatry 2015;14:119-36.
32. Torniainen M, Mittendorfer-Rutz E, Tanskanen A et al. Antipsychotic treatment and mortality in schizophrenia. Schizophr Bull 2015;41:656-63.
33. Cullen BA, McGinty EE, Zhang YY et al. Guideline-concordant antipsychotic use and mortality in schizophrenia. Schizophr Bull 2013;39:1159-68.
34. Foley DL, Morley KI. Systematic review of early cardiometabolic outcomes of the first treated episode of psychosis. Arch Gen Psychiatry 2011;68:609-16.
35. Lawrence D, Holman CDJ, Jablensky AV et al. Death rate from ischaemic heart disease in Western Australian psychiatric patients 1980-1998. Br J Psychiatry 2003;182:31-6.
36. Kisley S, Campbell LA, Wang Y. Treatment of ischemic heart disease and stroke in individuals with psychosis under universal health care. Br J Psychiatry 2009;195:545-50.
37. Laursen TM, Munk-Olsen T, Agerbo E et al. Somatic hospital contacts, invasive cardiac procedures, and mortality from heart disease in patients with severe mental disorder. Arch Gen Psychiatry 2009;66:713-20.
38. Chen YH, Lin HC, Lin HC. Poor clinical outcomes among pneumonia patients with schizophrenia. Schizophr Bull 2011;37:1088-94.
39. Daumit GL, Pronovost PJ, Anthony CB. Adverse events during medical and surgical hospitalizations for persons with schizophrenia. Arch Gen Psychiatry 2006;63:267-72.
40. Jones S, Howard L, Thornicroft G. ‘Diagnostic overshadowing’: worse physical health care for people with mental illness. Acta Psychiatr Scand 2008;118:169-71.
41. Corrigan PW, Mittal D, Reaves CM et al. Mental health stigma and primary health care decisions. Psychiatry Res 2014;218:35-8.
42. McGinty EE, Baller J, Azrin ST et al. Interventions to address medical conditions and health-risk behaviors among persons with serious mental illness: a comprehensive review. Schizophr Bull 2016;42:96-124.
43. Laursen TM, Munk-Olsen T, Gasse C. Chronic somatic comorbidity and excess mortality due to natural causes in persons with schizophrenia or bipolar affective disorder. PLoS One 2011;6:e24597.
44. Druss BG, Rosenheck RA. Mental disorders and access to medical care in the United States. Am J Psychiatry 1998;155:1775-7.
45. Morrison DS. Homelessness as an independent risk factor for mortality: results from a retrospective cohort study. Int J Epidemiol 2009;38:877-83.
46. Nielsen SF, Hjorthoj CR, Erlangsen A et al. Psychiatric disorders and mortality among people in homeless shelters in Denmark: a nationwide register-based cohort study. Lancet 2011;377:2205-14.
47. Kiviniemi M, Suvisaari J, Pirkola S et al. Five-year follow-up study of disability pension rates in first-onset schizophrenia with special focus on regional differences and mortality. Gen Hosp Psychiatry 2011;33:1445-52.
48. Druss BG, Zhao L, von Esenwein et al. Understanding excess mortality in persons with mental illness: 17-year follow up of a nationally representative US survey. Med Care 2011;49:599-604.
49. World Health Organization. Mental health gap action programme. Geneva: World Health Organization, 2008.
50. World Health Organization. Mental health gap action programme intervention guide. Geneva: World Health Organization, 2010.
51. Sampson S, Mansour M, Maayan N et al. Intermittent drug techniques for schizophrenia. Cochrane Database Syst Rev 2013;7:CD006196.
52. Tiihonen J, Lönnqvist J, Wahlbeck K et al. 11-year follow-up of mortality in patients with schizophrenia: a population-based cohort study (FIN11 study). Lancet 2009;374:1-12.
53. Buchanan RW, Kreyenbuhl J, Kelly DL et al. The 2009 schizophrenia PORT psychopharmacological treatment recommendations and summary statements. Schizophr Bull 2010;36:71-93.
54. McGuire AB, Kukla M, Green A et al. Illness management and recovery: a review of the literature. Psychiatr Serv 2014;65:171-9.
55. Dixon LB, Holoshitz Y, Nossel I. Treatment engagement of individuals experiencing mental illness: review and update. World Psychiatry 2016;15:13-20.
56. Haklai Z, Goldberger N, Stein N et al. The mortality risk among persons with psychiatric hospitalizations. Israel J Psychiatry Rel Sci 2011;48:230-9.
57. Organization for Economic Cooperation and Development. Health at a glance 2015. Geneva: Organization for Economic Cooperation and Development, 2015.
58. World Health Organization. Preventing suicide: a global imperative. Geneva: World Health Organization, 2014.
59. Hughes K, Bellis MA, Jones L et al. Prevalence and risk of violence against adults with disabilities: a systematic review and meta-analysis of observational studies. Lancet 2012;379:1621-9.
60. Evins AE, Cather C, Pratt SA et al. Maintenance treatment with varenicline for smoking cessation in patients with schizophrenia and bipolar disorder: a randomized clinical trial. JAMA 2014;311:145-54.
61. Daumit GL, Dickerson FB, Wang NY et al. A behavioural weight-loss intervention in persons with severe mental illness. N Engl J Med 2013;368:1594-602.
62. Green CA, Yarborough BJH, Leo MC et al. The STRIDE weight loss and lifestyle intervention for individuals taking antipsychotic medications: a randomized trial. Am J Psychiatry 2015;172:71-81.
63. Druss BG, Bornemann TH. Improving health and health care for persons with serious mental illness: the window for US federal policy change. JAMA 2010;303:1972-3.
64. Appel L, Champagne C, Harsha D et al. Effects of comprehensive lifestyle modification on blood pressure control: main results of the PREMIER clinical trial. Writing Group of the PREMIER Collaborative Research Group. JAMA 2003;289:2083-93.
65. Whelton PK, Appel LJ, Espeland MA et al. Sodium reduction and weight loss in the treatment of hypertension in older persons: a randomized controlled trial of nonpharmacologic interventions in the elderly (TONE). TONE Collaborative Research Group. JAMA 1998;279:839-46.
66. World Health Organization. Interventions on diet and physical activity: what works. Geneva: World Health Organization, 2009.
67. Drake RE, O'Neal E, Wallach MA. A systematic review of psychosocial interventions for people with co-occurring severe mental and substance use disorders. J Subst Abuse Treat 2008;34:123-38.
68. Mueser KT, Glynn SM, Cather C et al. Family interventions for co-occurring substance use and severe psychiatric disorders: participant characteristics and correlates of initial engagement and more extended exposure in a randomized controlled trial. Addict Behav 2012;34:864-77.
69. Rosenberg SD, Goldberg RW, Dixon LB et al. Assessing the STIRR model of best practices for blood-borne infections in clients with severe mental illness. Psychiatr Serv 2010;61:885-91.
70. World Health Organization. Strengthening health systems to improve health outcomes. WHO's framework for action. Geneva: World Health Organization, 2007.
71. Osborn D, Nazareth I, Wright CA et al. Impact of a nurse-led intervention to improve screening for cardiovascular risk factors in people with severe mental illness. Phase-two cluster randomized feasibility trial of community mental health teams. BMC Health Serv Res 2010;10:61-73.
72. Speyer H, Norgaard HCB, Birk M et al. The CHANGE trial: no superiority of lifestyle coaching plus care coordination plus treatment as usual compared to treatment as usual alone in reducing risk of cardiovascular disease in adults with schizophrenia spectrum disorders and abdominal obesity. World Psychiatry 2016;15:155-65.
73. Barnes TR, Paton C, Cavanagh MR et al. UK prescribing observatory for mental health. A UK audit of screening for the metabolic side effects of antipsychotics in community patients. Schizophr Bull 2007;33:1397-403.
74. National Institute for Health and Care Excellence. Lester UK adaptation. Positive cardiometabolic health resource. London: National Institute for Health and Care Excellence, 2014.
75. Substance Abuse and Mental Health Services Administration. A standard framework for levels of integrated healthcare. Washington: Substance Abuse and Mental Health Services Administration, 2013.
76. University of Western Australia. Clinical guidelines for the physical care of mental health consumers. Report. Perth: University of Western Australia, 2010.
77. University of Western Australia. Nurse practitioner protocols for managing the physical health of mental health patients guideline. Perth: University of Western Australia, 2010.
78. Shiers D, Curtis J. Cardiometabolic health in young people with psychosis. Lancet Psychiatry 2014;1:492-4.
79. Substance Abuse and Mental Health Services Administration, Center for Mental Health Services. Primary and behavioral health care integration grants (PBHCI). Washington: Substance Abuse and Mental Health Services Administration, 2014.
80. Scharf DM, Eberhart NK, Schmidt Hackbath N et al. Evaluation of the SAMSHA Primary and Behavioral Health Care Integration (PBHCI) Grant Program: final report. Santa Monica: RAND Corporation, 2014.
81. Stanley SH, Laugharne JDE. Clinical guidelines for the physical care of mental health consumers: a comprehensive assessment and monitoring package for mental health and primary care clinicians. Aust N Z J Psychiatry 2011;45:824-9.
82. New South Wales Government. Metabolic monitoring, a new mental health clinical documentation module. Sydney: New South Wales Government, 2012.
83. Organ B, Nicholson E, Castle D. Implementing a physical health strategy in a mental health service. Australas Psychiatry 2010;18:456-9.
84. Semrau M, Lempp H, Keynejad R et al. Service user and caregiver involvement in mental health system strengthening in low- and middle-income countries: systematic review. BMC Health Serv Res 2016;16:79.
85. Lorig KR, Sobel DS, Stewart AL et al. Evidence suggesting that a chronic disease self-management program can improve health status while reducing hospitalization: a randomized trial. Med Care 1999;37:5-14.
86. Druss BG, Zhao L, von Esenwein SA et al. The Health and Recovery Peer (HARP) Program: a peer-led intervention to improve medical self-management for persons with serious mental illness. Schizophr Res 2010;118:264-70.
87. Semrau M, Evans-Lacko S, Koschorke M et al. Stigma and discrimination related to mental illness in low- and middle-income countries. Epidemiol Psychiatr Sci 2015;24:382-94.
88. Thornicroft G, Metha N, Clement S et al. Evidence for effective interventions to reduce mental-health-related stigma and discrimination. Lancet 2016;387:1123-32.
89. Burns T, Catty J, Becker T et al. The effectiveness of supported employment for people with severe mental illness: a randomized controlled trial. Lancet 2007;370:1146-52.
90. Siu AL, US Preventive Services Task Force (USPSTF), Bibbins-Domingo K et al. Screening for depression in adults: US Preventive Services Task Force recommendation statement. JAMA 2016;315:380-7.
91. Schroeder SA. Smoking cessation should be an integral part of serious mental illness treatment. World Psychiatry 2016;15:175-6.
92. Dixon LB, Dickerson F, Bellack AS et al. The 2009 schizophrenia PORT psychosocial treatment recommendations and summary statements. Schizophr Bull 2010;36:48-70.
93. National Institute for Health and Care Excellence. Quality statement 7: promoting health eating, physical activity and smoking cessation. London: National Institute for Health and Care Excellence, 2015.
94. World Health Organization. Package of essential NCD interventions for primary health care: cancer, diabetes, heart disease and stroke, chronic respiratory disease. Geneva: World Health Organization, 2010.
95. Shidhaye R, Lund C, Chisholm D. Closing the treatment gap for mental, neurological and substance use disorders by strengthening existing health care platforms: strategies for delivery and integration of evidence-based interventions. Int J Ment Health Syst 2015;9:40.
96. Patel V. Lay health worker led intervention for depression and anxiety disorders in India: impact on clinical and disability outcomes over 12 months. Br J Psychiatry 2011;199:459-66.