A sperm-specific proteome-scale metabolic network model identifies non-glycolytic genes for energy deficiency in asthenozoospermia

Systems Biology in Reproductive Medicine

Volumn 63, Issue 2, 2017, Pages 100-112

  Asghari, Arvand ^a   Marashi, Sayed Amir ^a   Ansari Pour, Naser ^a  

^a UNIVERSITY OF TEHRAN   (Iran)

Author keywords

Asthenozoospermia; ATP production; energy metabolism; male infertility; model reconstruction; sperm motility

Indexed keywords

ADENOSINE TRIPHOSPHATE; BIOLOGICAL MARKER; CYTOCHROME C OXIDASE; FATTY ACID; INORGANIC PYROPHOSPHATASE; PROTEOME; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; SOLUTE CARRIER PROTEIN; UBIDECARENONE;

ARTICLE; ASTHENOSPERMIA; CITRIC ACID CYCLE; COMPUTER MODEL; ENERGY METABOLISM; FALSE NEGATIVE RESULT; FATTY ACID OXIDATION; GENE INACTIVATION; GLYCOLYSIS; MALE INFERTILITY; METABOLISM; MOLECULAR MODEL; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; PROTEOME SCALE METABOLIC NETWORK MODEL; SIMULATION; SPERM; ALGORITHM; BIOLOGICAL MODEL; COMPUTER SIMULATION; FERTILITY; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; GENETICS; GENOTYPE; HUMAN; MALE; PATHOLOGY; PHENOTYPE; PROCEDURES; PROTEIN DATABASE; PROTEIN PROTEIN INTERACTION; PROTEOMICS; SPERMATOZOON;

ALGORITHMS; ASTHENOZOOSPERMIA; COMPUTER SIMULATION; DATABASES, PROTEIN; ENERGY METABOLISM; FERTILITY; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORKS; GENOTYPE; HUMANS; MALE; MODELS, BIOLOGICAL; PHENOTYPE; PROTEIN INTERACTION MAPS; PROTEOME; PROTEOMICS; SPERMATOZOA;

EID: 85010702328     PISSN: 19396368     EISSN: 19396376     Source Type: Journal    
DOI: 10.1080/19396368.2016.1263367     Document Type: Article

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