A 45-SNP genetic risk score is increased in early-onset coronary artery disease but independent of familial disease clustering

Atherosclerosis

Volumn 257, Issue , 2017, Pages 172-178

  Christiansen, Morten K ^a,b   Nyegaard, Mette ^b   Pedersen, Lisbeth N ^a   Larsen, Sanne B ^a   Würtz, Morten ^a   Hjort, Jakob ^a   Kristensen, Steen D ^a,b   Jensen, Henrik K ^a,b  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b AARHUS UNIVERSITY   (Denmark)

Author keywords

Age of onset; Coronary artery disease; Genetics; Multifactorial inheritance

Indexed keywords

ACETYLSALICYLIC ACID; ANTIHYPERTENSIVE AGENT; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; GENETIC MARKER;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY DISEASE; CORONARY BLOOD VESSEL; CROSS-SECTIONAL STUDY; DIABETES MELLITUS; DISEASE DURATION; DISEASE SEVERITY; FAMILIAL DISEASE; FAMILIAL HYPERCHOLESTEROLEMIA; FAMILY; FEMALE; FIRST-DEGREE RELATIVE; GENETIC ASSOCIATION; GENETIC RISK; GENETIC RISK SCORE; GENOTYPE; HEART MUSCLE REVASCULARIZATION; HERITABILITY; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; PRIORITY JOURNAL; RATING SCALE; REGRESSION ANALYSIS; SCORING SYSTEM; SECOND-DEGREE RELATIVE; SINGLE NUCLEOTIDE POLYMORPHISM; STRATIFIED LOG RANK FAMILY SCORE; CASE CONTROL STUDY; CLUSTER ANALYSIS; CORONARY ANGIOGRAPHY; DIAGNOSTIC IMAGING; GENETIC ASSOCIATION STUDY; GENETIC MARKER; GENETIC PREDISPOSITION; GENETIC SCREENING; GENETICS; HEREDITY; MULTIFACTORIAL INHERITANCE; ONSET AGE; PEDIGREE; PHENOTYPE; PREDICTIVE VALUE; PROCEDURES; RISK ASSESSMENT; RISK FACTOR;

ADULT; AGE OF ONSET; AGED; CASE-CONTROL STUDIES; CLUSTER ANALYSIS; CORONARY ANGIOGRAPHY; CORONARY ARTERY DISEASE; CROSS-SECTIONAL STUDIES; FEMALE; GENETIC ASSOCIATION STUDIES; GENETIC MARKERS; GENETIC PREDISPOSITION TO DISEASE; GENETIC TESTING; HEREDITY; HUMANS; MALE; MIDDLE AGED; MULTIFACTORIAL INHERITANCE; PEDIGREE; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; PREDICTIVE VALUE OF TESTS; RISK ASSESSMENT; RISK FACTORS;

EID: 85010635823     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2017.01.010     Document Type: Article

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