Pathology of coronary atherosclerosis and thrombosis

Cardiovascular Diagnosis and Therapy

Volumn 6, Issue 4, 2016, Pages 396-408

  Otsuka, Fumiyuki ^a,b   Yasuda, Satoshi ^b   Noguchi, Teruo ^b   Ishibashi Ueda, Hatsue ^a  

^a NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^b Department of Cardiovascular Medicine ^*  (Japan)

Author keywords

Atherosclerosis; Coronary disease; Pathology; Thrombosis

Indexed keywords

COLLAGEN TYPE 1; COLLAGEN TYPE 3;

ARTERY INTIMA PROLIFERATION; ATHEROMA; ATHEROSCLEROTIC PLAQUE; BLEEDING; CALCIFIED NODULE; CORONARY ARTERY ATHEROSCLEROSIS; CORONARY ARTERY CALCIFICATION; CORONARY ARTERY DISEASE; CORONARY ARTERY REMODELING; CORONARY ARTERY THROMBOSIS; DISEASE COURSE; HUMAN; MORPHOMETRICS; NECROSIS; PATHOGENESIS; PATHOLOGIC INTIMAL THICKENING; PLAQUE EROSION; PLAQUE RUPTURE; REVIEW; SUDDEN CARDIAC DEATH; THIN CAP FIBROATHEROMA; XANTHOMA;

EID: 85010556315     PISSN: 22233652     EISSN: 22233660     Source Type: Journal    
DOI: 10.21037/cdt.2016.06.01     Document Type: Review

References (53)

1. Mozaffarian D, Benjamin EJ, Go AS, et al. Heart disease and stroke statistics-2015 update: A report from the American Heart Association. Circulation 2015;131:e29- 322.
2. Davies MJ, Thomas A. Thrombosis and acute coronaryartery lesions in sudden cardiac ischemic death. N Engl J Med 1984;310:1137-40.
3. Bentzon JF, Otsuka F, Virmani R, et al. Mechanisms of plaque formation and rupture. Circ Res 2014;114:1852-66.
4. Stary HC, Chandler AB, Glagov S, et al. A definition of initial, fatty streak, and intermediate lesions of atherosclerosis. A report from the committee on vascular lesions of the council on arteriosclerosis, american heart association. Circulation 1994;89:2462-78.
5. Virmani R, Kolodgie FD, Burke AP, et al. Lessons from sudden coronary death: A comprehensive morphological classification scheme for atherosclerotic lesions. Arterioscler Thromb Vasc Biol 2000;20:1262-75.
6. Velican C. A dissecting view on the role of the fatty streak in the pathogenesis of human atherosclerosis: Culprit or bystander? Med Interne 1981;19:321-37.
7. Imakita M, Yutani C, Strong JP, et al. Second nation-wide study of atherosclerosis in infants, children and young adults in japan. Atherosclerosis 2001;155:487-97.
8. Otsuka F, Kramer MC, Woudstra P, et al. Natural progression of atherosclerosis from pathologic intimal thickening to late fibroatheroma in human coronary arteries: A pathology study. Atherosclerosis 2015;241:772-82.
9. Nakashima Y, Fujii H, Sumiyoshi S, et al. Early human atherosclerosis: Accumulation of lipid and proteoglycans in intimal thickenings followed by macrophage infiltration. Arterioscler Thromb Vasc Biol 2007;27:1159-65.
10. Williams KJ. Interactions of lipoproteins with proteoglycans. Methods Mol Biol 2001;171:457-77.
11. Stary HC, Chandler AB, Dinsmore RE, et al. A definition of advanced types of atherosclerotic lesions and a histological classification of atherosclerosis. A report from the committee on vascular lesions of the council on arteriosclerosis, american heart association. Circulation 1995;92:1355-74.
12. Schrijvers DM, De Meyer GR, Herman AG, et al. Phagocytosis in atherosclerosis: Molecular mechanisms and implications for plaque progression and stability. Cardiovasc Res 2007;73:470-80.
13. Stupka N, Kintakas C, White JD, et al. Versican processing by a disintegrin-like and metalloproteinase domain with thrombospondin-1 repeats proteinases-5 and -15 facilitates myoblast fusion. J Biol Chem 2013;288:1907-17.
14. Burke AP, Farb A, Malcom GT, et al. Coronary risk factors and plaque morphology in men with coronary disease who died suddenly. N Engl J Med. 1997;336:1276-82.
15. Otsuka F, Joner M, Prati F, et al. Clinical classification of plaque morphology in coronary disease. Nat Rev Cardiol 2014;11:379-89.
16. Otsuka F, Finn AV, Virmani R. Do vulnerable and ruptured plaques hide in heavily calcified arteries? Atherosclerosis 2013;229:34-7.
17. Otsuka F, Sakakura K, Yahagi K, et al. Has our understanding of calcification in human coronary atherosclerosis progressed? Arterioscler Thromb Vasc Biol 2014;34:724-36.
18. Davies MJ, Thomas AC. Plaque fissuring-The cause of acute myocardial infarction, sudden ischaemic death, and crescendo angina. Br Heart J 1985;53:363-73.
19. Burke AP, Virmani R, Galis Z, et al. 34th bethesda conference: Task force #2-what is the pathologic basis for new atherosclerosis imaging techniques? J Am Coll Cardiol 2003;41:1874-86.
20. Kolodgie FD, Burke AP, Farb A, et al. The thin-capfibroatheroma: A type of vulnerable plaque: The major precursor lesion to acute coronary syndromes. Curr Opin Cardiol 2001;16:285-92.
21. Kockx MM, De Meyer GR, Muhring J, et al. Apoptosis and related proteins in different stages of human atherosclerotic plaques. Circulation 1998;97:2307-15.
22. Vengrenyuk Y, Carlier S, Xanthos S, et al. A hypothesis for vulnerable plaque rupture due to stress-induced debonding around cellular microcalcifications in thin fibrous caps. Proc Natl Acad Sci U S A 2006;103:14678-83.
23. Kelly-Arnold A, Maldonado N, Laudier D, et al. Revised microcalcification hypothesis for fibrous cap rupture in human coronary arteries. Proc Natl Acad Sci U S A 2013;110:10741-6.
24. New SE, Goettsch C, Aikawa M, et al. Macrophagederived matrix vesicles: An alternative novel mechanism for microcalcification in atherosclerotic plaques. Circ Res 2013;113:72-7.
25. Soor GS, Vukin I, Leong SW, et al. Peripheral vascular disease: Who gets it and why? A histomorphological analysis of 261 arterial segments from 58 cases. Pathology 2008;40:385-91.
26. Glagov S, Weisenberg E, Zarins CK, et al. Compensatory enlargement of human atherosclerotic coronary arteries. N Engl J Med 1987;316:1371-5.
27. Clarkson TB, Prichard RW, Morgan TM, et al. Remodeling of coronary arteries in human and nonhuman primates. JAMA 1994;271:289-94.
28. Burke AP, Kolodgie FD, Farb A, et al. Morphological predictors of arterial remodeling in coronary atherosclerosis. Circulation 2002;105:297-303.
29. Varnava AM, Mills PG, Davies MJ. Relationship between coronary artery remodeling and plaque vulnerability. Circulation 2002;105:939-43.
30. Schoenhagen P, Ziada KM, Kapadia SR, et al. Extent and direction of arterial remodeling in stable versus unstable coronary syndromes: An intravascular ultrasound study. Circulation 2000;101:598-603.
31. Motoyama S, Sarai M, Harigaya H, et al. Computed tomographic angiography characteristics of atherosclerotic plaques subsequently resulting in acute coronary syndrome. J Am Coll Cardiol 2009;54:49-57.
32. Yahagi K, Davis HR, Arbustini E, et al. Sex differences in coronary artery disease: Pathological observations. Atherosclerosis 2015;239:260-7.
33. Burke AP, Farb A, Malcom GT, et al. Plaque rupture and sudden death related to exertion in men with coronary artery disease. JAMA 1999;281:921-6.
34. Sukhova GK, Schonbeck U, Rabkin E, et al. Evidence for increased collagenolysis by interstitial collagenases-1 and -3 in vulnerable human atheromatous plaques. Circulation 1999;99:2503-9.
35. Gijsen FJ, Wentzel JJ, Thury A, et al. Strain distribution over plaques in human coronary arteries relates to shear stress. Am J Physiol Heart Circ Physiol 2008;295:H1608-14.
36. Silvain J, Collet JP, Nagaswami C, et al. Composition of coronary thrombus in acute myocardial infarction. J Am Coll Cardiol 2011;57:1359-67.
37. Farb A, Burke AP, Tang AL, et al. Coronary plaque erosion without rupture into a lipid core. A frequent cause of coronary thrombosis in sudden coronary death. Circulation 1996;93:1354-63.
38. Kolodgie FD, Burke AP, Farb A, et al. Differential accumulation of proteoglycans and hyaluronan in culprit lesions: Insights into plaque erosion. Arterioscler Thromb Vasc Biol 2002;22:1642-8.
39. van der Wal AC, Becker AE, van der Loos CM, et al. Site of intimal rupture or erosion of thrombosed coronary atherosclerotic plaques is characterized by an inflammatory process irrespective of the dominant plaque morphology. Circulation 1994;89:36-44.
40. Schwartz RS, Burke A, Farb A, et al. Microemboli and microvascular obstruction in acute coronary thrombosis and sudden coronary death: Relation to epicardial plaque histopathology. J Am Coll Cardiol 2009;54:2167-73.
41. Kramer MC, Rittersma SZ, de Winter RJ, et al. Relationship of thrombus healing to underlying plaque morphology in sudden coronary death. J Am Coll Cardiol 2010;55:122-32.
42. Ferrante G, Nakano M, Prati F, et al. High levels of systemic myeloperoxidase are associated with coronary plaque erosion in patients with acute coronary syndromes: A clinicopathological study. Circulation 2010;122:2505-13.
43. Sakakura K, Nakano M, Otsuka F, et al. Comparison of pathology of chronic total occlusion with and without coronary artery bypass graft. Eur Heart J 2014;35:1683-93.
44. Burke AP, Kolodgie FD, Farb A, et al. Healed plaque ruptures and sudden coronary death: Evidence that subclinical rupture has a role in plaque progression. Circulation 2001;103:934-40.
45. Mann J, Davies MJ. Mechanisms of progression in native coronary artery disease: Role of healed plaque disruption. Heart 1999;82:265-8.
46. Tabas I. Consequences of cellular cholesterol accumulation: Basic concepts and physiological implications. J Clin Invest 2002;110:905-11.
47. Yeagle PL. Cholesterol and the cell membrane. Biochim Biophys Acta 1985;822:267-87.
48. Kolodgie FD, Gold HK, Burke AP, et al. Intraplaque hemorrhage and progression of coronary atheroma. N Engl J Med 2003;349:2316-25.
49. Sluimer JC, Kolodgie FD, Bijnens AP, et al. Thinwalled microvessels in human coronary atherosclerotic plaques show incomplete endothelial junctions relevance of compromised structural integrity for intraplaque microvascular leakage. J Am Coll Cardiol 2009;53:1517-27.
50. Zhang Y, Cliff WJ, Schoefl GI, Higgins G. Plasma protein insudation as an index of early coronary atherogenesis. Am J Pathol 1993;143:496-506.
51. Michel JB, Thaunat O, Houard X, Meilhac O, Caligiuri G, Nicoletti A. Topological determinants and consequences of adventitial responses to arterial wall injury. Arterioscler Thromb Vasc Biol. 2007;27:1259-68.
52. Kolodgie FD, Virmani R, Burke AP, et al. Pathologic assessment of the vulnerable human coronary plaque. Heart. 2004;90:1385-91.
53. Virmani R, Burke AP, Kolodgie FD, Farb A. Vulnerable plaque: The pathology of unstable coronary lesions. J Interv Cardiol. 2002;15:439-46.