Folate-Targeted Surface-Enhanced Resonance Raman Scattering Nanoprobe Ratiometry for Detection of Microscopic Ovarian Cancer

ACS Nano

Volumn 11, Issue 2, 2017, Pages 1488-1497

  Oseledchyk, Anton ^a   Andreou, Chrysafis ^a   Wall, Matthew A ^a   Kircher, Moritz F ^a,b  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

molecular imaging; nanoparticle; ovarian cancer; Raman; SERS

Indexed keywords

DIAGNOSIS; DISEASES; MOLECULAR IMAGING; NANOPARTICLES; RAMAN SCATTERING; RESONANCE; TUMORS;

BIOLUMINESCENCE IMAGING; INTRA-OPERATIVE IMAGING; NANOPARTICLE (NPS); OVARIAN CANCERS; RAMAN; RATIOMETRIC IMAGING; SERS; SURFACE-ENHANCED RESONANCE RAMAN SCATTERING;

SURFACE SCATTERING;

FOLIC ACID; NANOPARTICLE;

ANIMAL; C57BL MOUSE; CHEMISTRY; DIAGNOSTIC IMAGING; DISEASE MODEL; EXPERIMENTAL NEOPLASM; FEMALE; FLUORESCENCE IMAGING; HUMAN; MOLECULAR PROBE; MOUSE; NANOTECHNOLOGY; NUDE MOUSE; OVARY TUMOR; RAMAN SPECTROMETRY; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; DISEASE MODELS, ANIMAL; FEMALE; FOLIC ACID; HUMANS; MICE; MICE, INBRED C57BL; MICE, NUDE; MOLECULAR PROBES; NANOPARTICLES; NANOTECHNOLOGY; NEOPLASMS, EXPERIMENTAL; OPTICAL IMAGING; OVARIAN NEOPLASMS; SPECTRUM ANALYSIS, RAMAN;

EID: 85010314781     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/acsnano.6b06796     Document Type: Article

References (29)

1. Siegel, R. L.; Miller, K. D.; Jemal, A. Cancer Statistics, 2015 Ca-Cancer J. Clin. 2015, 65, 5-29 10.3322/caac.21254
2. Burger, R. A.; Brady, M. F.; Bookman, M. A.; Fleming, G. F.; Monk, B. J.; Huang, H.; Mannel, R. S.; Homesley, H. D.; Fowler, J.; Greer, B. E.; Boente, M.; Birrer, M. J.; Liang, S. X. Incorporation of Bevacizumab in the Primary Treatment of Ovarian Cancer N. Engl. J. Med. 2011, 365, 2473-83 10.1056/NEJMoa1104390
3. Winter, W. E., 3rd; Maxwell, G. L.; Tian, C.; Sundborg, M. J.; Rose, G. S.; Rose, P. G.; Rubin, S. C.; Muggia, F.; McGuire, W. P. Tumor Residual after Surgical Cytoreduction in Prediction of Clinical Outcome in Stage Iv Epithelial Ovarian Cancer: A Gynecologic Oncology Group Study J. Clin. Oncol. 2008, 26, 83-9 10.1200/JCO.2007.13.1953
4. Armstrong, D. K.; Bundy, B.; Wenzel, L.; Huang, H. Q.; Baergen, R.; Lele, S.; Copeland, L. J.; Walker, J. L.; Burger, R. A. Intraperitoneal Cisplatin and Paclitaxel in Ovarian Cancer N. Engl. J. Med. 2006, 354, 34-43 10.1056/NEJMoa052985
5. Eisenhauer, E. L.; Abu-Rustum, N. R.; Sonoda, Y.; Aghajanian, C.; Barakat, R. R.; Chi, D. S. The Effect of Maximal Surgical Cytoreduction on Sensitivity to Platinum-Taxane Chemotherapy and Subsequent Survival in Patients with Advanced Ovarian Cancer Gynecol. Oncol. 2008, 108, 276-81 10.1016/j.ygyno.2007.10.022
6. Vergote, I. B.; Marth, C.; Coleman, R. L. Role of the Folate Receptor in Ovarian Cancer Treatment: Evidence, Mechanism, and Clinical Implications Cancer Metastasis Rev. 2015, 34, 41-52 10.1007/s10555-014-9539-8
7. van Dam, G. M.; Themelis, G.; Crane, L. M.; Harlaar, N. J.; Pleijhuis, R. G.; Kelder, W.; Sarantopoulos, A.; de Jong, J. S.; Arts, H. J.; van der Zee, A. G.; Bart, J.; Low, P. S.; Ntziachristos, V. Intraoperative Tumor-Specific Fluorescence Imaging in Ovarian Cancer by Folate Receptor-Alpha Targeting: First in-Human Results Nat. Med. 2011, 17, 1315-9 10.1038/nm.2472
8. Andreou, C.; Kishore, S. A.; Kircher, M. F. Surface-Enhanced Raman Spectroscopy: A New Modality for Cancer Imaging J. Nucl. Med. 2015, 56, 1295-9 10.2967/jnumed.115.158196
9. Thakor, A. S.; Gambhir, S. S. Nanooncology: The Future of Cancer Diagnosis and Therapy Ca-Cancer J. Clin. 2013, 63, 395-418 10.3322/caac.21199
10. Harmsen, S.; Bedics, M. A.; Wall, M. A.; Huang, R.; Detty, M. R.; Kircher, M. F. Rational Design of a Chalcogenopyrylium-Based Surface-Enhanced Resonance Raman Scattering Nanoprobe with Attomolar Sensitivity Nat. Commun. 2015, 6, 6570 10.1038/ncomms7570
11. Harmsen, S.; Huang, R.; Wall, M. A.; Karabeber, H.; Samii, J. M.; Spaliviero, M.; White, J. R.; Monette, S.; O'Connor, R.; Pitter, K. L.; Sastra, S. A.; Saborowski, M.; Holland, E. C.; Singer, S.; Olive, K. P.; Lowe, S. W.; Blasberg, R. G.; Kircher, M. F. Surface-Enhanced Resonance Raman Scattering Nanostars for High-Precision Cancer Imaging Sci. Transl. Med. 2015, 7, 271ra7 10.1126/scitranslmed.3010633
12. Huang, R.; Harmsen, S.; Samii, J. M.; Karabeber, H.; Pitter, K. L.; Holland, E. C.; Kircher, M. F. High Precision Imaging of Microscopic Spread of Glioblastoma with a Targeted Ultrasensitive Serrs Molecular Imaging Probe Theranostics 2016, 6, 1075-84 10.7150/thno.13842
13. Spaliviero, M.; Harmsen, S.; Huang, R.; Wall, M. A.; Andreou, C.; Eastham, J. A.; Touijer, K. A.; Scardino, P. T.; Kircher, M. F. Detection of Lymph Node Metastases with Serrs Nanoparticles Mol. Imaging Biol. 2016, 18, 677-85 10.1007/s11307-016-0932-2
14. Lengyel, E. Ovarian Cancer Development and Metastasis Am. J. Pathol. 2010, 177, 1053-64 10.2353/ajpath.2010.100105
15. Bamberger, E. S.; Perrett, C. W. Angiogenesis in Epithelian Ovarian Cancer Mol. Pathol. 2002, 55, 348-59 10.1136/mp.55.6.348
16. Folkman, J. What Is the Evidence That Tumors Are Angiogenesis Dependent? J. Natl. Cancer Inst. 1990, 82, 4-6 10.1093/jnci/82.1.4
17. Pallaoro, A.; Braun, G. B.; Moskovits, M. Quantitative Ratiometric Discrimination between Noncancerous and Cancerous Prostate Cells Based on Neuropilin-1 Overexpression Proc. Natl. Acad. Sci. U. S. A. 2011, 108, 16559-64 10.1073/pnas.1109490108
18. Wang, Y. W.; Khan, A.; Som, M.; Wang, D.; Chen, Y.; Leigh, S. Y.; Meza, D.; McVeigh, P. Z.; Wilson, B. C.; Liu, J. T. Rapid Ratiometric Biomarker Detection with Topically Applied Sers Nanoparticles Technology (Singap World Sci) 2014, 2, 118-132 10.1142/S2339547814500125
19. Andreou, C.; Neuschmelting, V.; Tschaharganeh, D. F.; Huang, C. H.; Oseledchyk, A.; Iacono, P.; Karabeber, H.; Colen, R. R.; Mannelli, L.; Lowe, S. W.; Kircher, M. F. Imaging of Liver Tumors Using Surface-Enhanced Raman Scattering Nanoparticles ACS Nano 2016, 10, 5015-26 10.1021/acsnano.5b07200
20. Hama, Y.; Urano, Y.; Koyama, Y.; Kamiya, M.; Bernardo, M.; Paik, R. S.; Krishna, M. C.; Choyke, P. L.; Kobayashi, H. In Vivo Spectral Fluorescence Imaging of Submillimeter Peritoneal Cancer Implants Using a Lectin-Targeted Optical Agent Neoplasia 2006, 8, 607-12 10.1593/neo.06268
21. Thakor, A. S.; Luong, R.; Paulmurugan, R.; Lin, F. I.; Kempen, P.; Zavaleta, C.; Chu, P.; Massoud, T. F.; Sinclair, R.; Gambhir, S. S. The Fate and Toxicity of Raman-Active Silica-Gold Nanoparticles in Mice Sci. Transl. Med. 2011, 3, 79ra33 10.1126/scitranslmed.3001963
22. Kircher, M. F.; de la Zerda, A.; Jokerst, J. V.; Zavaleta, C. L.; Kempen, P. J.; Mittra, E.; Pitter, K.; Huang, R.; Campos, C.; Habte, F.; Sinclair, R.; Brennan, C. W.; Mellinghoff, I. K.; Holland, E. C.; Gambhir, S. S. A Brain Tumor Molecular Imaging Strategy Using a New Triple-Modality Mri-Photoacoustic-Raman Nanoparticle Nat. Med. 2012, 18, 829-34 10.1038/nm.2721
23. Karabeber, H.; Huang, R.; Iacono, P.; Samii, J. M.; Pitter, K.; Holland, E. C.; Kircher, M. F. Guiding Brain Tumor Resection Using Surface-Enhanced Raman Scattering Nanoparticles and a Hand-Held Raman Scanner ACS Nano 2014, 8, 9755-66 10.1021/nn503948b
24. Oseledchyk, A.; Zivanovic, O. Intraoperative Hyperthermic Intraperitoneal Chemotherapy in Patients with Advanced Ovarian Cancer Oncology (Williston Park) 2015, 29, 695-701
25. Bohndiek, S. E.; Wagadarikar, A.; Zavaleta, C. L.; Van de Sompel, D.; Garai, E.; Jokerst, J. V.; Yazdanfar, S.; Gambhir, S. S. A Small Animal Raman Instrument for Rapid, Wide-Area, Spectroscopic Imaging Proc. Natl. Acad. Sci. U. S. A. 2013, 110, 12408-13 10.1073/pnas.1301379110
26. Demers, J. L.; Davis, S. C.; Pogue, B. W.; Morris, M. D. Multichannel Diffuse Optical Raman Tomography for Bone Characterization in Vivo: A Phantom Study Biomed. Opt. Express 2012, 3, 2299-305 10.1364/BOE.3.002299
27. Garai, E.; Sensarn, S.; Zavaleta, C. L.; Van de Sompel, D.; Loewke, N. O.; Mandella, M. J.; Gambhir, S. S.; Contag, C. H. High-Sensitivity, Real-Time, Ratiometric Imaging of Surface-Enhanced Raman Scattering Nanoparticles with a Clinically Translatable Raman Endoscope Device J. Biomed. Opt. 2013, 18, 096008 10.1117/1.JBO.18.9.096008
28. Stone, N.; Kerssens, M.; Lloyd, G. R.; Faulds, K.; Graham, D.; Matousek, P. Surface Enhanced Spatially Offset Raman Spectroscopic (Sesors) Imaging-the Next Dimension Chem. Sci. 2011, 2, 776-780 10.1039/c0sc00570c
29. Zavaleta, C. L.; Garai, E.; Liu, J. T.; Sensarn, S.; Mandella, M. J.; Van de Sompel, D.; Friedland, S.; Van Dam, J.; Contag, C. H.; Gambhir, S. S. A Raman-Based Endoscopic Strategy for Multiplexed Molecular Imaging Proc. Natl. Acad. Sci. U. S. A. 2013, 110, E2288-97 10.1073/pnas.1211309110