메뉴 건너뛰기




Volumn 23, Issue 1, 2017, Pages 193-203

CTLA-4 limits anti-CD20-mediated tumor regression

Author keywords

[No Author keywords available]

Indexed keywords

CD20 ANTIBODY; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; INTERFERON; CD20 ANTIGEN; CYTOKINE; IMMUNOLOGICAL ANTINEOPLASTIC AGENT; RITUXIMAB; TUMOR MARKER;

EID: 85010214313     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-16-0040     Document Type: Article
Times cited : (36)

References (44)
  • 1
    • 0026668842 scopus 로고
    • Monoclonal anti-idiotype antibody therapy of B-cell lymphoma: The addition of a short course of chemotherapy does not interfere with the antitumor effect nor prevent the emergence of idiotype-negative variant cells
    • Maloney DG, Brown S, Czerwinski DK, Liles TM, Hart SM, Miller RA, et al. Monoclonal anti-idiotype antibody therapy of B-cell lymphoma: the addition of a short course of chemotherapy does not interfere with the antitumor effect nor prevent the emergence of idiotype-negative variant cells. Blood 1992;80:1502-10.
    • (1992) Blood , vol.80 , pp. 1502-1510
    • Maloney, D.G.1    Brown, S.2    Czerwinski, D.K.3    Liles, T.M.4    Hart, S.M.5    Miller, R.A.6
  • 2
    • 0028127304 scopus 로고
    • Phase I clinical trial using escalating single-dose infusion of chimeric anti-CD20 monoclonal antibody (IDEC-C2B8) in patients with recurrent B-cell lymphoma
    • Maloney DG, Liles TM, Czerwinski DK, Waldichuk C, Rosenberg J, Grillo-Lopez A, et al. Phase I clinical trial using escalating single-dose infusion of chimeric anti-CD20 monoclonal antibody (IDEC-C2B8) in patients with recurrent B-cell lymphoma. Blood 1994;84:2457-66.
    • (1994) Blood , vol.84 , pp. 2457-2466
    • Maloney, D.G.1    Liles, T.M.2    Czerwinski, D.K.3    Waldichuk, C.4    Rosenberg, J.5    Grillo-Lopez, A.6
  • 3
    • 1842368507 scopus 로고    scopus 로고
    • IDEC-C2B8 (Rituximab) anti-CD20 monoclonal antibody therapy in patients with relapsed low-grade non-Hodgkin's lymphoma
    • Maloney DG, Grillo-Lopez AJ, White CA, Bodkin D, Schilder RJ, Neidhart JA, et al. IDEC-C2B8 (Rituximab) anti-CD20 monoclonal antibody therapy in patients with relapsed low-grade non-Hodgkin's lymphoma. Blood 1997;90:2188-95.
    • (1997) Blood , vol.90 , pp. 2188-2195
    • Maloney, D.G.1    Grillo-Lopez, A.J.2    White, C.A.3    Bodkin, D.4    Schilder, R.J.5    Neidhart, J.A.6
  • 4
    • 17144455839 scopus 로고    scopus 로고
    • IDEC-C2B8: Results of a phase I multiple-dose trial in patients with relapsed non-Hodgkin's lymphoma
    • Maloney DG, Grillo-Lopez AJ, Bodkin DJ, White CA, Liles TM, Royston I, et al. IDEC-C2B8: results of a phase I multiple-dose trial in patients with relapsed non-Hodgkin's lymphoma. J Clin Oncol 1997;15:3266-74.
    • (1997) J Clin Oncol , vol.15 , pp. 3266-3274
    • Maloney, D.G.1    Grillo-Lopez, A.J.2    Bodkin, D.J.3    White, C.A.4    Liles, T.M.5    Royston, I.6
  • 5
    • 84861409254 scopus 로고    scopus 로고
    • Anti-CD20 antibody therapy for B-cell lymphomas
    • Maloney DG. Anti-CD20 antibody therapy for B-cell lymphomas. N Engl J Med 2012;366:2008-16.
    • (2012) N Engl J Med , vol.366 , pp. 2008-2016
    • Maloney, D.G.1
  • 6
    • 0034076307 scopus 로고    scopus 로고
    • Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targets
    • Clynes RA, Towers TL, Presta LG, Ravetch JV. Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targets. Nat Med 2000;6:443-6.
    • (2000) Nat Med , vol.6 , pp. 443-446
    • Clynes, R.A.1    Towers, T.L.2    Presta, L.G.3    Ravetch, J.V.4
  • 7
    • 3042743884 scopus 로고    scopus 로고
    • Rituximab-dependent cytotoxicity by natural killer cells: Influence of FCGR3A polymorphism on the concentration-effect relationship
    • Dall'Ozzo S, Tartas S, Paintaud G, Cartron G, Colombat P, Bardos P, et al. Rituximab-dependent cytotoxicity by natural killer cells: influence of FCGR3A polymorphism on the concentration-effect relationship. Cancer Res 2004;64:4664-9.
    • (2004) Cancer Res , vol.64 , pp. 4664-4669
    • Dall'Ozzo, S.1    Tartas, S.2    Paintaud, G.3    Cartron, G.4    Colombat, P.5    Bardos, P.6
  • 8
    • 33750622479 scopus 로고    scopus 로고
    • Anti-CD20 monoclonal antibody with enhanced affinity for CD16 activates NK cells at lower concentrations and more effectively than rituximab
    • Bowles JA, Wang SY, Link BK, Allan B, Beuerlein G, Campbell MA, et al. Anti-CD20 monoclonal antibody with enhanced affinity for CD16 activates NK cells at lower concentrations and more effectively than rituximab. Blood 2006;108:2648-54.
    • (2006) Blood , vol.108 , pp. 2648-2654
    • Bowles, J.A.1    Wang, S.Y.2    Link, B.K.3    Allan, B.4    Beuerlein, G.5    Campbell, M.A.6
  • 9
    • 51649123832 scopus 로고    scopus 로고
    • Lymphoma depletion during CD20 immunotherapy in mice is mediated by macrophage FcγRI, FcγRIII, and FcγRIV
    • Minard-Colin V, Xiu Y, Poe JC, Horikawa M, Magro CM, Hamaguchi Y, et al. Lymphoma depletion during CD20 immunotherapy in mice is mediated by macrophage FcγRI, FcγRIII, and FcγRIV. Blood 2008;112:1205-13.
    • (2008) Blood , vol.112 , pp. 1205-1213
    • Minard-Colin, V.1    Xiu, Y.2    Poe, J.C.3    Horikawa, M.4    Magro, C.M.5    Hamaguchi, Y.6
  • 10
    • 3042592452 scopus 로고    scopus 로고
    • The innate mononuclear phagocyte network depletes B lymphocytes through Fc receptor-dependent mechanisms during anti-CD20 antibody immunotherapy
    • Uchida J, Hamaguchi Y, Oliver JA, Ravetch JV, Poe JC, Haas KM, et al. The innate mononuclear phagocyte network depletes B lymphocytes through Fc receptor-dependent mechanisms during anti-CD20 antibody immunotherapy. J Exp Med 2004;199:1659-69.
    • (2004) J Exp Med , vol.199 , pp. 1659-1669
    • Uchida, J.1    Hamaguchi, Y.2    Oliver, J.A.3    Ravetch, J.V.4    Poe, J.C.5    Haas, K.M.6
  • 11
    • 84928005736 scopus 로고    scopus 로고
    • Antagonistic human FcγRIIB (CD32B) antibodies have anti-tumor activity and overcome resistance to antibody therapy in vivo
    • Roghanian A, Teige I, Martensson L, Cox KL, Kovacek M, Ljungars A, et al. Antagonistic human FcγRIIB (CD32B) antibodies have anti-tumor activity and overcome resistance to antibody therapy in vivo. Cancer Cell 2015;27:473-88.
    • (2015) Cancer Cell , vol.27 , pp. 473-488
    • Roghanian, A.1    Teige, I.2    Martensson, L.3    Cox, K.L.4    Kovacek, M.5    Ljungars, A.6
  • 12
    • 77956545725 scopus 로고    scopus 로고
    • Long-lasting antitumor protection by anti-CD20 antibody through cellular immune response
    • Abes R, Gelize E, Fridman WH, Teillaud JL. Long-lasting antitumor protection by anti-CD20 antibody through cellular immune response. Blood 2010;116:926-34.
    • (2010) Blood , vol.116 , pp. 926-934
    • Abes, R.1    Gelize, E.2    Fridman, W.H.3    Teillaud, J.L.4
  • 13
    • 84930081913 scopus 로고    scopus 로고
    • Differential Fc-receptor engagement drives an antitumor vaccinal effect
    • DiLillo DJ, Ravetch JV. Differential Fc-receptor engagement drives an antitumor vaccinal effect. Cell 2015;161:1035-45.
    • (2015) Cell , vol.161 , pp. 1035-1045
    • DiLillo, D.J.1    Ravetch, J.V.2
  • 14
    • 77955534002 scopus 로고    scopus 로고
    • The therapeutic effect of anti-HER2/neu antibody depends on both innate and adaptive immunity
    • Park S, Jiang Z, Mortenson ED, Deng L, Radkevich-Brown O, Yang X, et al. The therapeutic effect of anti-HER2/neu antibody depends on both innate and adaptive immunity. Cancer Cell 2010;18:160-70.
    • (2010) Cancer Cell , vol.18 , pp. 160-170
    • Park, S.1    Jiang, Z.2    Mortenson, E.D.3    Deng, L.4    Radkevich-Brown, O.5    Yang, X.6
  • 15
    • 79955570584 scopus 로고    scopus 로고
    • Anti-ErbB-2 mAb therapy requires type I and II interferons and synergizes with anti-PD-1 or anti-CD137 mAb therapy
    • Stagg J, Loi S, Divisekera U, Ngiow SF, Duret H, Yagita H, et al. Anti-ErbB-2 mAb therapy requires type I and II interferons and synergizes with anti-PD-1 or anti-CD137 mAb therapy. Proc Natl Acad Sci U S A 2011;108:7142-7.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 7142-7147
    • Stagg, J.1    Loi, S.2    Divisekera, U.3    Ngiow, S.F.4    Duret, H.5    Yagita, H.6
  • 16
    • 0642312825 scopus 로고    scopus 로고
    • Rituximab (monoclonal anti-CD20 antibody): Mechanisms of action and resistance
    • Smith MR. Rituximab (monoclonal anti-CD20 antibody): mechanisms of action and resistance. Oncogene 2003;22:7359-68.
    • (2003) Oncogene , vol.22 , pp. 7359-7368
    • Smith, M.R.1
  • 17
    • 78751524881 scopus 로고    scopus 로고
    • Interindividual variability of response to rituximab: From biological origins to individualized therapies
    • Cartron G, Trappe RU, Solal-Celigny P, Hallek M. Interindividual variability of response to rituximab: from biological origins to individualized therapies. Clin Cancer Res 2011;17:19-30.
    • (2011) Clin Cancer Res , vol.17 , pp. 19-30
    • Cartron, G.1    Trappe, R.U.2    Solal-Celigny, P.3    Hallek, M.4
  • 22
    • 84879759020 scopus 로고    scopus 로고
    • Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma
    • Hamid O, Robert C, Daud A, Hodi FS, Hwu WJ, Kefford R, et al. Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma. N Engl J Med 2013;369:134-44.
    • (2013) N Engl J Med , vol.369 , pp. 134-144
    • Hamid, O.1    Robert, C.2    Daud, A.3    Hodi, F.S.4    Hwu, W.J.5    Kefford, R.6
  • 26
    • 84901215262 scopus 로고    scopus 로고
    • The cellular and molecular origin of tumor-associated macrophages
    • Franklin RA, Liao W, Sarkar A, Kim MV, Bivona MR, Liu K, et al. The cellular and molecular origin of tumor-associated macrophages. Science 2014;344:921-5.
    • (2014) Science , vol.344 , pp. 921-925
    • Franklin, R.A.1    Liao, W.2    Sarkar, A.3    Kim, M.V.4    Bivona, M.R.5    Liu, K.6
  • 27
  • 28
    • 79953295544 scopus 로고    scopus 로고
    • The efficacy of radiotherapy relies upon induction of type I interferon-dependent innate and adaptive immunity
    • Burnette BC, Liang H, Lee Y, Chlewicki L, Khodarev NN, Weichselbaum RR, et al. The efficacy of radiotherapy relies upon induction of type I interferon-dependent innate and adaptive immunity. Cancer Res 2011;71:2488-96.
    • (2011) Cancer Res , vol.71 , pp. 2488-2496
    • Burnette, B.C.1    Liang, H.2    Lee, Y.3    Chlewicki, L.4    Khodarev, N.N.5    Weichselbaum, R.R.6
  • 29
    • 80355136945 scopus 로고    scopus 로고
    • Host type I IFN signals are required for antitumor CD8+ T cell responses through CD8{alpha}+ dendritic cells
    • Fuertes MB, Kacha AK, Kline J, Woo SR, Kranz DM, Murphy KM, et al. Host type I IFN signals are required for antitumor CD8+ T cell responses through CD8{alpha}+ dendritic cells. J Exp Med 2011;208:2005-16.
    • (2011) J Exp Med , vol.208 , pp. 2005-2016
    • Fuertes, M.B.1    Kacha, A.K.2    Kline, J.3    Woo, S.R.4    Kranz, D.M.5    Murphy, K.M.6
  • 30
    • 84977161108 scopus 로고    scopus 로고
    • Mechanism of tumor rejection with doublets of CTLA-4, PD-1/PD-L1, or IDO blockade involves restored IL-2 production and proliferation of CD8 (+) T cells directly within the tumor microenvironment
    • Spranger S, Koblish HK, Horton B, Scherle PA, Newton R, Gajewski TF. Mechanism of tumor rejection with doublets of CTLA-4, PD-1/PD-L1, or IDO blockade involves restored IL-2 production and proliferation of CD8 (+) T cells directly within the tumor microenvironment. J Immunother Cancer 2014;2:3.
    • (2014) J Immunother Cancer , vol.2 , pp. 3
    • Spranger, S.1    Koblish, H.K.2    Horton, B.3    Scherle, P.A.4    Newton, R.5    Gajewski, T.F.6
  • 31
    • 84943630992 scopus 로고    scopus 로고
    • CD47 blockade triggers T cell-mediated destruction of immunogenic tumors
    • Liu X, Pu Y, Cron K, Deng L, Kline J, Frazier WA, et al. CD47 blockade triggers T cell-mediated destruction of immunogenic tumors. Nat Med 2015;21:1209-15.
    • (2015) Nat Med , vol.21 , pp. 1209-1215
    • Liu, X.1    Pu, Y.2    Cron, K.3    Deng, L.4    Kline, J.5    Frazier, W.A.6
  • 32
    • 84858766182 scopus 로고    scopus 로고
    • The blockade of immune checkpoints in cancer immunotherapy
    • Pardoll DM. The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer 2012;12:252-64.
    • (2012) Nat Rev Cancer , vol.12 , pp. 252-264
    • Pardoll, D.M.1
  • 34
    • 84884271914 scopus 로고    scopus 로고
    • Fc-dependent depletion of tumor-infiltrating regulatory T cells codefines the efficacy of anti-CTLA-4 therapy against melanoma
    • Simpson TR, Li F, Montalvo-Ortiz W, Sepulveda MA, Bergerhoff K, Arce F, et al. Fc-dependent depletion of tumor-infiltrating regulatory T cells codefines the efficacy of anti-CTLA-4 therapy against melanoma. J Exp Med 2013;210:1695-710.
    • (2013) J Exp Med , vol.210 , pp. 1695-1710
    • Simpson, T.R.1    Li, F.2    Montalvo-Ortiz, W.3    Sepulveda, M.A.4    Bergerhoff, K.5    Arce, F.6
  • 35
    • 84878936788 scopus 로고    scopus 로고
    • Anti-CTLA-4 antibodies of IgG2a isotype enhance antitumor activity through reduction of intratumoral regulatory T cells
    • Selby MJ, Engelhardt JJ, Quigley M, Henning KA, Chen T, Srinivasan M, et al. Anti-CTLA-4 antibodies of IgG2a isotype enhance antitumor activity through reduction of intratumoral regulatory T cells. Cancer Immunol Res 2013;1:32-42.
    • (2013) Cancer Immunol Res , vol.1 , pp. 32-42
    • Selby, M.J.1    Engelhardt, J.J.2    Quigley, M.3    Henning, K.A.4    Chen, T.5    Srinivasan, M.6
  • 36
  • 37
    • 33749132564 scopus 로고    scopus 로고
    • Blockade of CTLA-4 on CD4+CD25+ regulatory T cells abrogates their function in vivo
    • Read S, Greenwald R, Izcue A, Robinson N, Mandelbrot D, Francisco L, et al. Blockade of CTLA-4 on CD4+CD25+ regulatory T cells abrogates their function in vivo. J Immunol 2006;177:4376-83.
    • (2006) J Immunol , vol.177 , pp. 4376-4383
    • Read, S.1    Greenwald, R.2    Izcue, A.3    Robinson, N.4    Mandelbrot, D.5    Francisco, L.6
  • 38
    • 0034679560 scopus 로고    scopus 로고
    • Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4
    • Takahashi T, Tagami T, Yamazaki S, Uede T, Shimizu J, Sakaguchi N, et al. Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. J Exp Med 2000;192:303-10.
    • (2000) J Exp Med , vol.192 , pp. 303-310
    • Takahashi, T.1    Tagami, T.2    Yamazaki, S.3    Uede, T.4    Shimizu, J.5    Sakaguchi, N.6
  • 39
    • 84941615057 scopus 로고    scopus 로고
    • Cytotoxic T lymphocyte antigen-4 and immune checkpoint blockade
    • Buchbinder E, Hodi FS. Cytotoxic T lymphocyte antigen-4 and immune checkpoint blockade. J Clin Invest 2015;125:3377-83.
    • (2015) J Clin Invest , vol.125 , pp. 3377-3383
    • Buchbinder, E.1    Hodi, F.S.2
  • 40
    • 65549085367 scopus 로고    scopus 로고
    • Rituximab immunotherapy results in the induction of a lymphoma idiotype-specific T-cell response in patients with follicular lymphoma: Support for a "vaccinal effect" of rituximab
    • Hilchey SP, Hyrien O, Mosmann TR, Livingstone AM, Friedberg JW, Young F, et al. Rituximab immunotherapy results in the induction of a lymphoma idiotype-specific T-cell response in patients with follicular lymphoma: support for a "vaccinal effect" of rituximab. Blood 2009;113:3809-12.
    • (2009) Blood , vol.113 , pp. 3809-3812
    • Hilchey, S.P.1    Hyrien, O.2    Mosmann, T.R.3    Livingstone, A.M.4    Friedberg, J.W.5    Young, F.6
  • 42
    • 34948886712 scopus 로고    scopus 로고
    • Adaptive immune cells temper initial innate responses
    • Kim KD, Zhao J, Auh S, Yang X, Du P, Tang H, et al. Adaptive immune cells temper initial innate responses. Nat Med 2007;13:1248-52.
    • (2007) Nat Med , vol.13 , pp. 1248-1252
    • Kim, K.D.1    Zhao, J.2    Auh, S.3    Yang, X.4    Du, P.5    Tang, H.6
  • 43
    • 84892416698 scopus 로고    scopus 로고
    • Targeting the tumor microenvironment with interferon-beta bridges innate and adaptive immune responses
    • Yang X, Zhang X, Fu ML, Weichselbaum RR, Gajewski TF, Guo Y, et al. Targeting the tumor microenvironment with interferon-beta bridges innate and adaptive immune responses. Cancer Cell 2014;25:37-48.
    • (2014) Cancer Cell , vol.25 , pp. 37-48
    • Yang, X.1    Zhang, X.2    Fu, M.L.3    Weichselbaum, R.R.4    Gajewski, T.F.5    Guo, Y.6
  • 44
    • 70350244852 scopus 로고    scopus 로고
    • Phase I study of ipilimumab, an anti-CTLA-4 monoclonal antibody, in patients with relapsed and refractory B-cell non-Hodgkin lymphoma
    • Ansell SM, Hurvitz SA, Koenig PA, LaPlant BR, Kabat BF, Fernando D, et al. Phase I study of ipilimumab, an anti-CTLA-4 monoclonal antibody, in patients with relapsed and refractory B-cell non-Hodgkin lymphoma. Clin Cancer Res 2009;15:6446-53.
    • (2009) Clin Cancer Res , vol.15 , pp. 6446-6453
    • Ansell, S.M.1    Hurvitz, S.A.2    Koenig, P.A.3    LaPlant, B.R.4    Kabat, B.F.5    Fernando, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.