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Volumn 110, Issue 5, 2017, Pages 629-639

The role of glutamine synthetase in energy production and glutamine metabolism during oxidative stress

Author keywords

ATP budget; Glutamine synthetase; Metabolic networks; Oxidative stress

Indexed keywords

ACETATE KINASE; ADENOSINE TRIPHOSPHATE; ADENYLATE KINASE; GLUTAMATE AMMONIA LIGASE; GLUTAMINE; HYDROGEN PEROXIDE; NUCLEOSIDE DIPHOSPHATE KINASE; OXYGEN; PHOSPHOENOLPYRUVATE CARBOXYLASE; PYRUVATE PHOSPHATE DIKINASE; CULTURE MEDIUM; OXIDIZING AGENT;

EID: 85009798899     PISSN: 00036072     EISSN: 15729699     Source Type: Journal    
DOI: 10.1007/s10482-017-0829-3     Document Type: Article
Times cited : (37)

References (41)
  • 1
    • 84902550952 scopus 로고    scopus 로고
    • Zinc toxicity and ATP production in Pseudomonas fluorescens
    • COI: 1:CAS:528:DC%2BC2cXhtVSqt73O
    • Alhasawi A, Auger C, Appanna VP, Chahma M, Appanna VD (2014) Zinc toxicity and ATP production in Pseudomonas fluorescens. J Appl Microbial 117(1):65–73. doi:10.1111/jam.12497
    • (2014) J Appl Microbial , vol.117 , Issue.1 , pp. 65-73
    • Alhasawi, A.1    Auger, C.2    Appanna, V.P.3    Chahma, M.4    Appanna, V.D.5
  • 2
    • 84944279972 scopus 로고    scopus 로고
    • Aspartate metabolism and pyruvate homeostasis triggered by oxidative stress in Pseudomonas fluorescens: a functional metabolomics study
    • COI: 1:CAS:528:DC%2BC2MXht1OqtbvM
    • Alhasawi A, Leblanc M, Appanna ND, Auger C, Appanna VD (2015) Aspartate metabolism and pyruvate homeostasis triggered by oxidative stress in Pseudomonas fluorescens: a functional metabolomics study. Metabolomics 11:1792–1801. doi:10.1007/s11306-015-0841-4
    • (2015) Metabolomics , vol.11 , pp. 1792-1801
    • Alhasawi, A.1    Leblanc, M.2    Appanna, N.D.3    Auger, C.4    Appanna, V.D.5
  • 3
    • 84982993825 scopus 로고    scopus 로고
    • From Krebs to clinic: glutamine metabolism to cancer therapy
    • COI: 1:CAS:528:DC%2BC28Xht12jurbI, PID: 27492215
    • Altman BJ, Stine ZE, Dang CV (2016) From Krebs to clinic: glutamine metabolism to cancer therapy. Nat Rev Cancer 16:619–634. doi:10.1038/nrc.2016.71:619-634
    • (2016) Nat Rev Cancer , vol.16 , pp. 619-634
    • Altman, B.J.1    Stine, Z.E.2    Dang, C.V.3
  • 5
    • 84981717705 scopus 로고    scopus 로고
    • Phospho-transfer networks and ATP homeostasis in response to an ineffective electron transport chain in Pseudomonas fluorescens
    • COI: 1:CAS:528:DC%2BC28Xht1aitbrO, PID: 27431058
    • Appanna VP, Alhasawi AA, Auger C, Thomas SC, Appanna VD (2016) Phospho-transfer networks and ATP homeostasis in response to an ineffective electron transport chain in Pseudomonas fluorescens. Arch Biochem Biophys 606:26–33. doi:10.1016/j.abb.2016.07.011
    • (2016) Arch Biochem Biophys , vol.606 , pp. 26-33
    • Appanna, V.P.1    Alhasawi, A.A.2    Auger, C.3    Thomas, S.C.4    Appanna, V.D.5
  • 6
    • 84908371743 scopus 로고    scopus 로고
    • A novel ATP-generating machinery to counter nitrosative stress is mediated by substrate-level phosphorylation
    • COI: 1:CAS:528:DC%2BC2cXhslemu7vN, PID: 25304769
    • Auger C, Appanna VD (2015) A novel ATP-generating machinery to counter nitrosative stress is mediated by substrate-level phosphorylation. Biochim Biophys Acta 1850:43–50. doi:10.1016/j.bbagen.2014.09.028
    • (2015) Biochim Biophys Acta , vol.1850 , pp. 43-50
    • Auger, C.1    Appanna, V.D.2
  • 7
    • 82455174382 scopus 로고    scopus 로고
    • The metabolic reprogramming evoked by nitrosative stress triggers the anaerobic utilization of citrate in Pseudomonas fluorescens
    • COI: 1:CAS:528:DC%2BC3MXhs1GgtbbL, PID: 22145048
    • Auger C, Lemire J, Cecchini D, Bignucolo A, Appanna VD (2011) The metabolic reprogramming evoked by nitrosative stress triggers the anaerobic utilization of citrate in Pseudomonas fluorescens. PLoS ONE 6(12):e28469. doi:10.1371/journal.pone.0028469
    • (2011) PLoS ONE , vol.6 , Issue.12
    • Auger, C.1    Lemire, J.2    Cecchini, D.3    Bignucolo, A.4    Appanna, V.D.5
  • 10
    • 84882256368 scopus 로고    scopus 로고
    • Hydrogen peroxide stress provokes a metabolic reprogramming in Pseudomonas fluorescens: enhanced production of pyruvate
    • COI: 1:CAS:528:DC%2BC3sXhtlCnsbbK, PID: 23871654
    • Bignucolo A, Appanna VP, Thomas SC, Auger C, Han S, Omri A, Appanna VD (2013) Hydrogen peroxide stress provokes a metabolic reprogramming in Pseudomonas fluorescens: enhanced production of pyruvate. J Biotechnol 167(3):309–315. doi:10.1016/j.jbiotec.2013.07.002
    • (2013) J Biotechnol , vol.167 , Issue.3 , pp. 309-315
    • Bignucolo, A.1    Appanna, V.P.2    Thomas, S.C.3    Auger, C.4    Han, S.5    Omri, A.6    Appanna, V.D.7
  • 11
    • 0343963067 scopus 로고    scopus 로고
    • Role of glutamine on the de novo purine nucleotide synthesis in Caco-2 cells
    • COI: 1:CAS:528:DC%2BD3cXktlGit7Y%3D, PID: 10900556
    • Boza JJ, Moënnoz D, Bournot CE, Blum S, Zbinden I, Finot PA, Ballèvre O (2000) Role of glutamine on the de novo purine nucleotide synthesis in Caco-2 cells. Eur J Nutr 39(1):38–46
    • (2000) Eur J Nutr , vol.39 , Issue.1 , pp. 38-46
    • Boza, J.J.1    Moënnoz, D.2    Bournot, C.E.3    Blum, S.4    Zbinden, I.5    Finot, P.A.6    Ballèvre, O.7
  • 12
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • COI: 1:CAS:528:DyaE28XksVehtrY%3D, PID: 942051
    • Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248–254
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 13
    • 79251517382 scopus 로고    scopus 로고
    • Regulation of cancer cell metabolism
    • COI: 1:CAS:528:DC%2BC3MXps1ahuw%3D%3D, PID: 21258394
    • Cairns RA, Harris IS, Mak TW (2011) Regulation of cancer cell metabolism. Nat Rev Cancer 11(2):85–95. doi:10.1038/nrc2981
    • (2011) Nat Rev Cancer , vol.11 , Issue.2 , pp. 85-95
    • Cairns, R.A.1    Harris, I.S.2    Mak, T.W.3
  • 14
    • 84868019043 scopus 로고    scopus 로고
    • Cancer cell metabolism: one hallmark, many faces
    • COI: 1:CAS:528:DC%2BC38XhsFagtLrJ, PID: 23009760
    • Cantor JR, Sabatini DM (2012) Cancer cell metabolism: one hallmark, many faces. Cancer discov 2(10):881–898. doi:10.1158/2159-8290.CD-12-0345
    • (2012) Cancer discov , vol.2 , Issue.10 , pp. 881-898
    • Cantor, J.R.1    Sabatini, D.M.2
  • 16
    • 85012045784 scopus 로고    scopus 로고
    • Central role of glutamate metabolism in the maintenance of nitrogen homeostasis in normal and hyperammonemic brain
    • Cooper AJ, jeitner tm (2016) central role of glutamate metabolism in the maintenance of nitrogen homeostasis in normal and hyperammonemic brain. Biomolecules 6(2):1–16. doi:10.3390/biom6020016
    • (2016) Biomolecules , vol.6 , Issue.2 , pp. 1-16
    • Cooper, A.J.1
  • 17
    • 20244378176 scopus 로고    scopus 로고
    • ATP generation in the Trypanosoma brucei procyclic form cytosolic substrate level phosphorylation is essential, but not oxidative phosphorylation
    • COI: 1:CAS:528:DC%2BD3sXptlGrtbo%3D, PID: 14506274
    • Coustou V, Besteiro S, Biran M, Diolez P, Bouchaud V, Voisin P, Michels PA, Canioni P, Baltz T, Bringaud F (2003) ATP generation in the Trypanosoma brucei procyclic form cytosolic substrate level phosphorylation is essential, but not oxidative phosphorylation. J Biol Chem 278(49):49625–49635
    • (2003) J Biol Chem , vol.278 , Issue.49 , pp. 49625-49635
    • Coustou, V.1    Besteiro, S.2    Biran, M.3    Diolez, P.4    Bouchaud, V.5    Voisin, P.6    Michels, P.A.7    Canioni, P.8    Baltz, T.9    Bringaud, F.10
  • 19
    • 75149148563 scopus 로고    scopus 로고
    • Q’s next: the diverse functions of glutamine in metabolism, cell biology and cancer
    • COI: 1:CAS:528:DC%2BD1MXhtlers7fE, PID: 19881548
    • DeBerardinis RJ, Cheng T (2010) Q’s next: the diverse functions of glutamine in metabolism, cell biology and cancer. Oncogene 29(3):313–324. doi:10.1038/onc.2009.358
    • (2010) Oncogene , vol.29 , Issue.3 , pp. 313-324
    • DeBerardinis, R.J.1    Cheng, T.2
  • 20
    • 0038037716 scopus 로고    scopus 로고
    • Phosphotransfer networks and cellular energetics
    • COI: 1:CAS:528:DC%2BD3sXlslaltb8%3D, PID: 12756286
    • Dzeja PP, Terzic A (2003) Phosphotransfer networks and cellular energetics. J Exp Biol 206(12):2039–2047
    • (2003) J Exp Biol , vol.206 , Issue.12 , pp. 2039-2047
    • Dzeja, P.P.1    Terzic, A.2
  • 21
    • 9144228368 scopus 로고    scopus 로고
    • Loss of glutamine synthetase in the human epileptogenic hippocampus: possible mechanism for raised extracellular glutamate in mesial temporal lobe epilepsy
    • COI: 1:CAS:528:DC%2BD2cXos1aj, PID: 14723991
    • Eid T, Thomas MJ, Spencer DD, Runden-Pran E, Lai JC, Malthankar GV, De Lanerolle NC (2004) Loss of glutamine synthetase in the human epileptogenic hippocampus: possible mechanism for raised extracellular glutamate in mesial temporal lobe epilepsy. Lancet 363(9402):28–37
    • (2004) Lancet , vol.363 , Issue.9402 , pp. 28-37
    • Eid, T.1    Thomas, M.J.2    Spencer, D.D.3    Runden-Pran, E.4    Lai, J.C.5    Malthankar, G.V.6    De Lanerolle, N.C.7
  • 22
    • 84865313576 scopus 로고    scopus 로고
    • Reverse TCA cycle flux through isocitrate dehydrogenases 1 and 2 is required for lipogenesis in hypoxic melanoma cells
    • COI: 1:CAS:528:DC%2BC38XpsFOmsbY%3D, PID: 22360810
    • Filipp FV, Scott DA, Ronai ZA, Osterman AL, Smith JW (2012) Reverse TCA cycle flux through isocitrate dehydrogenases 1 and 2 is required for lipogenesis in hypoxic melanoma cells. Pigment Cell Melanoma Res 25(3):375–383. doi:10.1111/j.1755-148X.2012.00989.x
    • (2012) Pigment Cell Melanoma Res , vol.25 , Issue.3 , pp. 375-383
    • Filipp, F.V.1    Scott, D.A.2    Ronai, Z.A.3    Osterman, A.L.4    Smith, J.W.5
  • 23
    • 84883497454 scopus 로고    scopus 로고
    • Glutamine and cancer: cell biology, physiology, and clinical opportunities
    • COI: 1:CAS:528:DC%2BC3sXhsVenu7bL, PID: 23999442
    • Hensley CT, Wasti AT, DeBerardinis RJ (2013) Glutamine and cancer: cell biology, physiology, and clinical opportunities. J Clin investig 123(9):3678–3684. doi:10.1172/JCI69600
    • (2013) J Clin investig , vol.123 , Issue.9 , pp. 3678-3684
    • Hensley, C.T.1    Wasti, A.T.2    DeBerardinis, R.J.3
  • 24
    • 0034847451 scopus 로고    scopus 로고
    • Mechanisms governing the expression of the enzymes of glutamine metabolism—glutaminase and glutamine synthetase
    • COI: 1:CAS:528:DC%2BD3MXmslGls74%3D, PID: 11533295
    • Labow BI, Souba WW, Abcouwer SF (2001) Mechanisms governing the expression of the enzymes of glutamine metabolism—glutaminase and glutamine synthetase. J Nutr 131(9):2467S–2474S
    • (2001) J Nutr , vol.131 , Issue.9 , pp. 2467S-2474S
    • Labow, B.I.1    Souba, W.W.2    Abcouwer, S.F.3
  • 25
    • 84941072886 scopus 로고    scopus 로고
    • Regulation of mammalian nucleotide metabolism and biosynthesis
    • COI: 1:CAS:528:DC%2BC2MXhsFaitrzN, PID: 25628363
    • Lane A, Fan TWM (2015) Regulation of mammalian nucleotide metabolism and biosynthesis. Nucl Acids Res 43:2466–2485. doi:10.1093/nar/gkv047
    • (2015) Nucl Acids Res , vol.43 , pp. 2466-2485
    • Lane, A.1    Fan, T.W.M.2
  • 26
    • 77954710252 scopus 로고    scopus 로고
    • Histidine is a source of the antioxidant, α-ketoglutarate, in Pseudomonas fluorescens challenged by oxidative stress
    • COI: 1:CAS:528:DC%2BC3cXhtVeju73F, PID: 20597986
    • Lemire J, Milandu Y, Auger C, Bignucolo A, Appanna VP, Appanna VD (2010) Histidine is a source of the antioxidant, α-ketoglutarate, in Pseudomonas fluorescens challenged by oxidative stress. FEMS Microbiol Lett 309(2):170–177
    • (2010) FEMS Microbiol Lett , vol.309 , Issue.2 , pp. 170-177
    • Lemire, J.1    Milandu, Y.2    Auger, C.3    Bignucolo, A.4    Appanna, V.P.5    Appanna, V.D.6
  • 28
    • 43049181940 scopus 로고    scopus 로고
    • A novel metabolic network leads to enhanced citrate biogenesis in Pseudomonas fluorescens exposed to aluminum toxicity
    • COI: 1:CAS:528:DC%2BD1cXltlCksrc%3D, PID: 18335165
    • Mailloux RJ, Lemire J, Kalyuzhnyi S, Appanna V (2008) A novel metabolic network leads to enhanced citrate biogenesis in Pseudomonas fluorescens exposed to aluminum toxicity. Extremophiles 12(3):451–459. doi:10.1007/s00792-008-0150-1
    • (2008) Extremophiles , vol.12 , Issue.3 , pp. 451-459
    • Mailloux, R.J.1    Lemire, J.2    Kalyuzhnyi, S.3    Appanna, V.4
  • 29
    • 60249089099 scopus 로고    scopus 로고
    • Alpha-Ketoglutarate abrogates the nuclear localization of HIF-α in aluminum-exposed hepatocytes
    • COI: 1:CAS:528:DC%2BD1MXit1Klur8%3D, PID: 19028544
    • Mailloux RJ, Puiseux-Dao S, Appanna VD (2009) Alpha-Ketoglutarate abrogates the nuclear localization of HIF-α in aluminum-exposed hepatocytes. Biochimie 91(3):408–415. doi:10.1016/j.biochi.2008.10.014
    • (2009) Biochimie , vol.91 , Issue.3 , pp. 408-415
    • Mailloux, R.J.1    Puiseux-Dao, S.2    Appanna, V.D.3
  • 32
    • 0025453971 scopus 로고
    • Glutamine metabolism and its physiologic importance
    • Robert SJ (1990) Glutamine metabolism and its physiologic importance. JPEN J Parenter Enter Nutr 14(4):40S–44S
    • (1990) JPEN J Parenter Enter Nutr , vol.14 , Issue.4 , pp. 40S-44S
    • Robert, S.J.1
  • 33
    • 0035487278 scopus 로고    scopus 로고
    • Glutamate as a substrate for glutamine synthetase
    • COI: 1:CAS:528:DC%2BD3MXns1Wis7w%3D, PID: 11571143
    • Robinson P, Neelon K, Schreier HJ, Roberts MF (2001) β-Glutamate as a substrate for glutamine synthetase. Appl Environ Microbiol 67(10):4458–4463
    • (2001) Appl Environ Microbiol , vol.67 , Issue.10 , pp. 4458-4463
    • Robinson, P.1    Neelon, K.2    Schreier, H.J.3    Roberts, M.F.4
  • 34
    • 84937918061 scopus 로고    scopus 로고
    • Variation in the link between oxygen consumption and ATP production, and its relevance for animal performance
    • PID: 26203001
    • Salin K, Auer SK, Rey B, Selman C, Metcalfe NB (2015) Variation in the link between oxygen consumption and ATP production, and its relevance for animal performance. Proc Biol Sci 282(1812):20151028. doi:10.1098/rspb
    • (2015) Proc Biol Sci , vol.282 , Issue.1812 , pp. 20151028
    • Salin, K.1    Auer, S.K.2    Rey, B.3    Selman, C.4    Metcalfe, N.B.5
  • 35
    • 0026409298 scopus 로고
    • Blue native electrophoresis for isolation of membrane protein complexes in enzymatically active form
    • COI: 1:STN:280:DyaK383lsV2rug%3D%3D, PID: 1812789
    • Schagger H, von Jagow G (1991) Blue native electrophoresis for isolation of membrane protein complexes in enzymatically active form. Anal Biochem 199(2):223–231
    • (1991) Anal Biochem , vol.199 , Issue.2 , pp. 223-231
    • Schagger, H.1    von Jagow, G.2
  • 36
    • 84904720029 scopus 로고    scopus 로고
    • Regulation systems of bacteria such as Escherichia coli in response to nutrient limitation and environmental stresses
    • PID: 24958385
    • Shimizu K (2013) Regulation systems of bacteria such as Escherichia coli in response to nutrient limitation and environmental stresses. Metabolites 4(1):1–35
    • (2013) Metabolites , vol.4 , Issue.1 , pp. 1-35
    • Shimizu, K.1
  • 37
    • 34548563918 scopus 로고    scopus 로고
    • Oxidative stress evokes a metabolic adaptation that favors increased NADPH synthesis and decreased NADH production in Pseudomonas fluorescens
    • COI: 1:CAS:528:DC%2BD2sXhtVKlsrnE, PID: 17573472
    • Singh R, Mailloux RJ, Puiseux-Dao S, Appanna VD (2007) Oxidative stress evokes a metabolic adaptation that favors increased NADPH synthesis and decreased NADH production in Pseudomonas fluorescens. J Bacteriol 189(18):6665–6675
    • (2007) J Bacteriol , vol.189 , Issue.18 , pp. 6665-6675
    • Singh, R.1    Mailloux, R.J.2    Puiseux-Dao, S.3    Appanna, V.D.4
  • 38
    • 70350221706 scopus 로고    scopus 로고
    • An ATP and oxalate generating variant tricarboxylic acid cycle counters aluminum toxicity in Pseudomonas fluorescens
    • PID: 19809498
    • Singh R, Lemire J, Mailloux RJ, Chénier D, Hamel R, Appanna VD (2009) An ATP and oxalate generating variant tricarboxylic acid cycle counters aluminum toxicity in Pseudomonas fluorescens. PLoS ONE 4(10):e7344. doi:10.1371/journal.pone.0007344
    • (2009) PLoS ONE , vol.4 , Issue.10
    • Singh, R.1    Lemire, J.2    Mailloux, R.J.3    Ch́énier, D.4    Hamel, R.5    Appanna, V.D.6
  • 40
    • 6444227759 scopus 로고    scopus 로고
    • Detoxification of hydrogen peroxide and expression of catalase genes in rhodobacter
    • COI: 1:CAS:528:DC%2BD2cXptVyjtLg%3D, PID: 15470122
    • Zeller T, Klug G (2004) Detoxification of hydrogen peroxide and expression of catalase genes in rhodobacter. Microbiology 150(10):3451–3462
    • (2004) Microbiology , vol.150 , Issue.10 , pp. 3451-3462
    • Zeller, T.1    Klug, G.2


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