Inhibition of collagen production by ICG-001, a small molecule inhibitor for Wnt/β-catenin signaling, in skin fibroblasts

Journal of Dermatological Science

Volumn 86, Issue 1, 2017, Pages 76-78

  Kim, Kyung Il ^a   Jeong, Do Sun ^a   Yoon, Tae Jin ^a   Jung, Eui Chang ^b   Lee, Jeung Hoon ^c,d   Kim, Chang Deok ^c  

^a Gyeongsang National University School of Medicine   (South Korea)

^b Gyeongsang National University   (South Korea)

^c Chungnam National University   (South Korea)

^d Skin Med Co   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; COLLAGEN TYPE 1; COLLAGEN TYPE I ALPHA 1; COLLAGEN TYPE I ALPHA 2; MESSENGER RNA; N BENZYL 1,2,3,4,8,9 HEXAHYDRO 6 (4 HYDROXYBENZYL) 8 (1 NAPHTHYLMETHYL) 4,7 DIOXO 2H PYRAZINO[1,2 A]PYRIMIDINE 1(6H) CARBOXAMIDE; PROCOLLAGEN; UNCLASSIFIED DRUG; WNT PROTEIN; COLLAGEN; FUSED HETEROCYCLIC RINGS; PYRIMIDINONE DERIVATIVE;

CELL CONTRACTION ASSAY; COLLAGEN SYNTHESIS; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DOWN REGULATION; DRUG MECHANISM; ELISA KIT; HUMAN; HUMAN CELL; HUMAN TISSUE; INTRACELLULAR SIGNALING; KELOID; LETTER; PROTEIN SECRETION; SKIN FIBROBLAST; TRANSCRIPTION TERMINATION; WESTERN BLOTTING; CYTOLOGY; DRUG EFFECT; FIBROBLAST; HYPERTROPHIC SCAR; METABOLISM; PATHOLOGY; PRECLINICAL STUDY; PRIMARY CELL CULTURE; SKIN; WNT SIGNALING;

BRIDGED BICYCLO COMPOUNDS, HETEROCYCLIC; CICATRIX, HYPERTROPHIC; COLLAGEN; DRUG EVALUATION, PRECLINICAL; FIBROBLASTS; HUMANS; KELOID; PRIMARY CELL CULTURE; PYRIMIDINONES; SKIN; WNT SIGNALING PATHWAY;

EID: 85009792761     PISSN: 09231811     EISSN: 1873569X     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2017.01.005     Document Type: Letter

References (10)

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