메뉴 건너뛰기




Volumn 92, Issue 2, 2017, Pages 204-208

Thrombotic issues in transgender medicine: A review

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ANTIANDROGEN; ANTICOAGULANT AGENT; CONJUGATED ESTROGEN; ESTRADIOL VALERATE; ESTROGEN; ETHINYLESTRADIOL; PROGESTERONE; SEX HORMONE; TESTOSTERONE;

EID: 85009773778     PISSN: 03618609     EISSN: 10968652     Source Type: Journal    
DOI: 10.1002/ajh.24593     Document Type: Review
Times cited : (81)

References (54)
  • 2
    • 84890019886 scopus 로고    scopus 로고
    • Progress on the road to better medical care for transgender patients
    • Gardner IH, Safer JD. Progress on the road to better medical care for transgender patients. Curr Opin Endocrinol DiabetesObes 2013;20:553–558.
    • (2013) Curr Opin Endocrinol DiabetesObes , vol.20 , pp. 553-558
    • Gardner, I.H.1    Safer, J.D.2
  • 3
    • 84925127060 scopus 로고    scopus 로고
    • Hormone therapy in transgender adults is safe with provider supervision: A review of hormone therapy sequelae for transgender individuals
    • Weinand JD, Safer JD. Hormone therapy in transgender adults is safe with provider supervision: A review of hormone therapy sequelae for transgender individuals. J Clin Transl Endocrinol 2015;2:55–60.
    • (2015) J Clin Transl Endocrinol , vol.2 , pp. 55-60
    • Weinand, J.D.1    Safer, J.D.2
  • 4
    • 84978370200 scopus 로고    scopus 로고
    • Beyond bathrooms—Meeting the health needs of transgender people
    • Schuster MA, Reisner SL, Onorato SE. Beyond bathrooms—Meeting the health needs of transgender people. N Engl J Med 2016;375:101–103.
    • (2016) N Engl J Med , vol.375 , pp. 101-103
    • Schuster, M.A.1    Reisner, S.L.2    Onorato, S.E.3
  • 5
    • 35649015758 scopus 로고    scopus 로고
    • Current management of male-to-female gender identity disorder in the UK
    • Tugnet N, Goddard JC, Vickery RM, et al. Current management of male-to-female gender identity disorder in the UK. Postgraduate Med J 2007;83:638–642.
    • (2007) Postgraduate Med J , vol.83 , pp. 638-642
    • Tugnet, N.1    Goddard, J.C.2    Vickery, R.M.3
  • 6
    • 69949085361 scopus 로고    scopus 로고
    • Endocrine treatment of transsexual persons: An endocrine society clinical practice guideline
    • Hembree WC, Cohen-Kettenis P, Delemarre-van de Waal HA, et al. Endocrine treatment of transsexual persons: An endocrine society clinical practice guideline. J Clin Endocrinol Metab 2009;94:3132–3154.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 3132-3154
    • Hembree, W.C.1    Cohen-Kettenis, P.2    Delemarre-van de Waal, H.A.3
  • 7
    • 85009803481 scopus 로고    scopus 로고
    • World Professional Association for Transgender Health. Standards of care for the health of transsexual, transgendergender nonconforming people. 7th edition., 20V27%20-%202011%202020WPATH.pdf Accessed February 14th, 2015.
    • World Professional Association for Transgender Health. Standards of care for the health of transsexual, transgender, and gender nonconforming people. 7th edition. 2011; Available at: http://www.wpath.org/documents/Standards%20of%20Care% 20V27%20-%202011%202020WPATH.pdf Available at. Accessed February 14th, 2015.
    • (2011)
  • 8
    • 79953221118 scopus 로고    scopus 로고
    • Care of transsexual persons
    • Gooren LJ. Care of transsexual persons. N Engl J Med 2011;364:1251–1257.
    • (2011) N Engl J Med , vol.364 , pp. 1251-1257
    • Gooren, L.J.1
  • 9
    • 10744233448 scopus 로고    scopus 로고
    • Differential effects of oral and transdermal estrogen/progesterone regimens on sensitivity to activated protein C among postmenopausal women: A randomized trial
    • Oger E, Alhenc-Gelas M, Lacut K, et al. Differential effects of oral and transdermal estrogen/progesterone regimens on sensitivity to activated protein C among postmenopausal women: A randomized trial. Arterioscler Thromb Vasc Biol 2003;23:1671–1676.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 1671-1676
    • Oger, E.1    Alhenc-Gelas, M.2    Lacut, K.3
  • 10
    • 0033401976 scopus 로고    scopus 로고
    • Biological coagulation findings in third-generation oral contraceptives
    • Conard J. Biological coagulation findings in third-generation oral contraceptives. Hum Reprod Update 1999;5:672–680.
    • (1999) Hum Reprod Update , vol.5 , pp. 672-680
    • Conard, J.1
  • 11
    • 44849131373 scopus 로고    scopus 로고
    • Hormone replacement therapy and risk of venous thromboembolism in postmenopausal women: Systematic review and meta-analysis
    • Canonico M, Plu-Bureau G, Lowe GD, Scarabin PY. Hormone replacement therapy and risk of venous thromboembolism in postmenopausal women: Systematic review and meta-analysis. BMJ (Clin Res Ed) 2008;336:1227–1231.
    • (2008) BMJ (Clin Res Ed) , vol.336 , pp. 1227-1231
    • Canonico, M.1    Plu-Bureau, G.2    Lowe, G.D.3    Scarabin, P.Y.4
  • 12
    • 34147169563 scopus 로고    scopus 로고
    • Incidence and mortality of venous thrombosis: A population-based study
    • Naess IA, Christiansen SC, Romundstad P, et al. Incidence and mortality of venous thrombosis: A population-based study. J Thromb Haemost 2007;5:692–699.
    • (2007) J Thromb Haemost , vol.5 , pp. 692-699
    • Naess, I.A.1    Christiansen, S.C.2    Romundstad, P.3
  • 13
    • 0034533428 scopus 로고    scopus 로고
    • Increased risk of recurrent venous thromboembolism during hormone replacement therapy—Results of the randomized, double-blind, placebo-controlled estrogen in venous thromboembolism trial (EVTET)
    • Hoibraaten E, Qvigstad E, Arnesen H, et al. Increased risk of recurrent venous thromboembolism during hormone replacement therapy—Results of the randomized, double-blind, placebo-controlled estrogen in venous thromboembolism trial (EVTET). Thrombosis Haemostasis 2000;84:961–967.
    • (2000) Thrombosis Haemostasis , vol.84 , pp. 961-967
    • Hoibraaten, E.1    Qvigstad, E.2    Arnesen, H.3
  • 14
    • 77955924407 scopus 로고    scopus 로고
    • Risk of venous thrombosis with oral versus transdermal estrogen therapy among postmenopausal women
    • Olie V, Canonico M, Scarabin PY. Risk of venous thrombosis with oral versus transdermal estrogen therapy among postmenopausal women. Curr Opin Hematol 2010;17:457–463.
    • (2010) Curr Opin Hematol , vol.17 , pp. 457-463
    • Olie, V.1    Canonico, M.2    Scarabin, P.Y.3
  • 15
    • 84858027124 scopus 로고    scopus 로고
    • Androgen deprivation and thromboembolic events in men with prostate cancer
    • Ehdaie B, Atoria CL, Gupta A, et al. Androgen deprivation and thromboembolic events in men with prostate cancer. Cancer 2012;118:3397–3406.
    • (2012) Cancer , vol.118 , pp. 3397-3406
    • Ehdaie, B.1    Atoria, C.L.2    Gupta, A.3
  • 16
    • 0022456711 scopus 로고
    • Cardiovascular complications of estrogen therapy for nondisseminated prostatic carcinoma. A preliminary report from a randomized multicenter study
    • Lundgren R, Sundin T, Colleen S, et al. Cardiovascular complications of estrogen therapy for nondisseminated prostatic carcinoma. A preliminary report from a randomized multicenter study. Scand J Urol Nephrol 1986;20:101–105.
    • (1986) Scand J Urol Nephrol , vol.20 , pp. 101-105
    • Lundgren, R.1    Sundin, T.2    Colleen, S.3
  • 17
    • 84884892231 scopus 로고    scopus 로고
    • Prevalence of cardiovascular disease and cancer during cross-sex hormone therapy in a large cohort of trans persons: A case–control study
    • Wierckx K, Elaut E, Declercq E, et al. Prevalence of cardiovascular disease and cancer during cross-sex hormone therapy in a large cohort of trans persons: A case–control study. Eur J Endocrinol 2013;169:471–478.
    • (2013) Eur J Endocrinol , vol.169 , pp. 471-478
    • Wierckx, K.1    Elaut, E.2    Declercq, E.3
  • 18
    • 84867396807 scopus 로고    scopus 로고
    • Long-term evaluation of cross-sex hormone treatment in transsexual persons
    • Wierckx K, Mueller S, Weyers S, et al. Long-term evaluation of cross-sex hormone treatment in transsexual persons. J Sex Med 2012;9:2641–2651.
    • (2012) J Sex Med , vol.9 , pp. 2641-2651
    • Wierckx, K.1    Mueller, S.2    Weyers, S.3
  • 19
    • 29144519245 scopus 로고    scopus 로고
    • Sexual and physical health after sex reassignment surgery
    • De Cuypere G, T'Sjoen G, Beerten R, et al. Sexual and physical health after sex reassignment surgery. Arch Sex Behav 2005;34:679–690.
    • (2005) Arch Sex Behav , vol.34 , pp. 679-690
    • De Cuypere, G.1    T'Sjoen, G.2    Beerten, R.3
  • 20
    • 77049097707 scopus 로고    scopus 로고
    • Incidence of thrombophilia and venous thrombosis in transsexuals under cross-sex hormone therapy
    • Ott J, Kaufmann U, Bentz EK, et al. Incidence of thrombophilia and venous thrombosis in transsexuals under cross-sex hormone therapy. Fertility Sterility 2010;93:1267–1272.
    • (2010) Fertility Sterility , vol.93 , pp. 1267-1272
    • Ott, J.1    Kaufmann, U.2    Bentz, E.K.3
  • 21
    • 62849097915 scopus 로고    scopus 로고
    • Effects of high dose oestrogen therapy on circulating inflammatory markers
    • Wilson R, Spiers A, Ewan J, et al. Effects of high dose oestrogen therapy on circulating inflammatory markers. Maturitas 2009;62:281–286.
    • (2009) Maturitas , vol.62 , pp. 281-286
    • Wilson, R.1    Spiers, A.2    Ewan, J.3
  • 22
    • 84905022543 scopus 로고    scopus 로고
    • Cross-sex hormone therapy in trans persons is safe and effective at short-time follow-up: Results from the European network for the investigation of gender incongruence
    • Wierckx K, Van Caenegem E, Schreiner T, et al. Cross-sex hormone therapy in trans persons is safe and effective at short-time follow-up: Results from the European network for the investigation of gender incongruence. J Sex Med 2014;11:1999–2011.
    • (2014) J Sex Med , vol.11 , pp. 1999-2011
    • Wierckx, K.1    Van Caenegem, E.2    Schreiner, T.3
  • 24
    • 0024616648 scopus 로고
    • Spironolactone with physiological female steroids for presurgical therapy of male-to-female transsexualism
    • Prior JC, Vigna YM, Watson D. Spironolactone with physiological female steroids for presurgical therapy of male-to-female transsexualism. Arch Sex Behav 1989;18:49–57.
    • (1989) Arch Sex Behav , vol.18 , pp. 49-57
    • Prior, J.C.1    Vigna, Y.M.2    Watson, D.3
  • 26
    • 0031664661 scopus 로고    scopus 로고
    • A follow-up study for estimating the effectiveness of a cross-gender hormone substitution therapy on transsexual patients
    • Schlatterer K, Yassouridis A, von Werder K, et al. A follow-up study for estimating the effectiveness of a cross-gender hormone substitution therapy on transsexual patients. Arch Sex Behav 1998;27:475–492.
    • (1998) Arch Sex Behav , vol.27 , pp. 475-492
    • Schlatterer, K.1    Yassouridis, A.2    von Werder, K.3
  • 27
    • 0033598657 scopus 로고    scopus 로고
    • Morbidity in transsexual patients with cross-gender hormone self-treatment
    • Becerra FA, de Luis Roman DA, Piedrola Maroto G. Morbidity in transsexual patients with cross-gender hormone self-treatment. Med Clin 1999;113:484–487.
    • (1999) Med Clin , vol.113 , pp. 484-487
    • Becerra, F.A.1    de Luis Roman, D.A.2    Piedrola Maroto, G.3
  • 28
    • 13444253761 scopus 로고    scopus 로고
    • Phase II study of transdermal estradiol in androgen-independent prostate carcinoma
    • Bland LB, Garzotto M, DeLoughery TG, et al. Phase II study of transdermal estradiol in androgen-independent prostate carcinoma. Cancer 2005;103:717–723.
    • (2005) Cancer , vol.103 , pp. 717-723
    • Bland, L.B.1    Garzotto, M.2    DeLoughery, T.G.3
  • 29
    • 33645032251 scopus 로고    scopus 로고
    • Postmenopausal hormone replacement therapy and venous thromboembolism
    • Wu O. Postmenopausal hormone replacement therapy and venous thromboembolism. Gender Med 2005;2(SupplA):S18–S27.
    • (2005) Gender Med , vol.2SupplA , pp. S18-S27
    • Wu, O.1
  • 30
    • 77949821581 scopus 로고    scopus 로고
    • Clinical guidelines for testing for heritable thrombophilia
    • Baglin T, Gray E, Greaves M, et al. Clinical guidelines for testing for heritable thrombophilia. Br J Haematol 2010;149:209–220.
    • (2010) Br J Haematol , vol.149 , pp. 209-220
    • Baglin, T.1    Gray, E.2    Greaves, M.3
  • 31
    • 84869441338 scopus 로고    scopus 로고
    • Low-dose aspirin for preventing recurrent venous thromboembolism
    • Brighton TA, Eikelboom JW, Mann K, et al. Low-dose aspirin for preventing recurrent venous thromboembolism. N Engl J Med 2012;367:1979–1987.
    • (2012) N Engl J Med , vol.367 , pp. 1979-1987
    • Brighton, T.A.1    Eikelboom, J.W.2    Mann, K.3
  • 32
    • 0037014630 scopus 로고    scopus 로고
    • Noncardiovascular disease outcomes during 6.8 years of hormone therapy: Heart and estrogen/progestin replacement study follow-up (hers ii)
    • Hulley S, Furberg C, Barrett-Connor E, et al. Noncardiovascular disease outcomes during 6.8 years of hormone therapy: Heart and estrogen/progestin replacement study follow-up (hers ii). JAMA 2002;288:58–64.
    • (2002) JAMA , vol.288 , pp. 58-64
    • Hulley, S.1    Furberg, C.2    Barrett-Connor, E.3
  • 33
    • 4644238003 scopus 로고    scopus 로고
    • EStrogen plus progestin and risk of venous thrombosis
    • Cushman M, Kuller LH, Prentice R, et al. EStrogen plus progestin and risk of venous thrombosis. JAMA 2004;292:1573–1580.
    • (2004) JAMA , vol.292 , pp. 1573-1580
    • Cushman, M.1    Kuller, L.H.2    Prentice, R.3
  • 34
    • 84962573834 scopus 로고    scopus 로고
    • Recurrent venous thromboembolism and abnormal uterine bleeding with anticoagulant and hormone therapy use
    • Martinelli I, Lensing AW, Middeldorp S, et al. Recurrent venous thromboembolism and abnormal uterine bleeding with anticoagulant and hormone therapy use. Blood 2016;127:1417–1425.
    • (2016) Blood , vol.127 , pp. 1417-1425
    • Martinelli, I.1    Lensing, A.W.2    Middeldorp, S.3
  • 35
    • 49749127056 scopus 로고    scopus 로고
    • Association between hormone replacement therapy and subsequent arterial and venous vascular events: A meta-analysis
    • Sare GM, Gray LJ, Bath PMW. Association between hormone replacement therapy and subsequent arterial and venous vascular events: A meta-analysis. Eur Heart J 2008;29:2031–2041.
    • (2008) Eur Heart J , vol.29 , pp. 2031-2041
    • Sare, G.M.1    Gray, L.J.2    Bath, P.M.W.3
  • 36
    • 84890066528 scopus 로고    scopus 로고
    • Venous thrombo-embolism as a complication of cross-sex hormone treatment of male-to-female transsexual subjects: A review
    • Asscheman H, T'Sjoen G, Lemaire A, et al. Venous thrombo-embolism as a complication of cross-sex hormone treatment of male-to-female transsexual subjects: A review. Andrologia 2014;46:791–795.
    • (2014) Andrologia , vol.46 , pp. 791-795
    • Asscheman, H.1    T'Sjoen, G.2    Lemaire, A.3
  • 37
    • 2142780403 scopus 로고    scopus 로고
    • Estrogen and thromboembolic disorders: Should patients stop hormones prior to cosmetic surgery?
    • Shiffman MA. Estrogen and thromboembolic disorders: Should patients stop hormones prior to cosmetic surgery? J Women's Health 2003;12:853–855.
    • (2003) J Women's Health , vol.12 , pp. 853-855
    • Shiffman, M.A.1
  • 38
    • 0035040856 scopus 로고    scopus 로고
    • Hormone replacement therapy (HRT) and anaesthesia
    • Brighouse D. Hormone replacement therapy (HRT) and anaesthesia. Br J Anaesth 2001;86:709–716.
    • (2001) Br J Anaesth , vol.86 , pp. 709-716
    • Brighouse, D.1
  • 39
    • 84880358130 scopus 로고    scopus 로고
    • Thrombosis in three postmenopausal women receiving testosterone therapy for low libido
    • Glueck CJ, Bowe D, Valdez A, Wang P. Thrombosis in three postmenopausal women receiving testosterone therapy for low libido. Women's Health (London, England) 2013;9:405–410.
    • (2013) Women's Health (London, England) , vol.9 , pp. 405-410
    • Glueck, C.J.1    Bowe, D.2    Valdez, A.3    Wang, P.4
  • 40
    • 84896880734 scopus 로고    scopus 로고
    • Testosterone therapy, thrombophilia-hypofibrinolysis, and hospitalization for deep venous thrombosis-pulmonary embolus: An exploratory, hypothesis-generating study
    • Glueck CJ, Richardson-Royer C, Schultz R, et al. Testosterone therapy, thrombophilia-hypofibrinolysis, and hospitalization for deep venous thrombosis-pulmonary embolus: An exploratory, hypothesis-generating study. Clin Appl Thromb Hemostasis Off J Int Acad Clin Appl Thromb Hemostasis 2014;20:244–249.
    • (2014) Clin Appl Thromb Hemostasis Off J Int Acad Clin Appl Thromb Hemostasis , vol.20 , pp. 244-249
    • Glueck, C.J.1    Richardson-Royer, C.2    Schultz, R.3
  • 41
    • 84938750645 scopus 로고    scopus 로고
    • Risk of venous thromboembolism in men receiving testosterone therapy
    • Baillargeon J, Urban RJ, Morgentaler A, et al. Risk of venous thromboembolism in men receiving testosterone therapy. Mayo Clin Proc 2015;90:1038–1045.
    • (2015) Mayo Clin Proc , vol.90 , pp. 1038-1045
    • Baillargeon, J.1    Urban, R.J.2    Morgentaler, A.3
  • 42
    • 84959036202 scopus 로고    scopus 로고
    • Effects of testosterone treatment in older men
    • Snyder PJ, Bhasin S, Cunningham GR, et al. Effects of testosterone treatment in older men. N Engl J Med 2016;374:611–624.
    • (2016) N Engl J Med , vol.374 , pp. 611-624
    • Snyder, P.J.1    Bhasin, S.2    Cunningham, G.R.3
  • 43
    • 22144437631 scopus 로고    scopus 로고
    • Testosterone therapy in women: A review
    • Bolour S, Braunstein G. Testosterone therapy in women: A review. Int J Impotence Res 2005;17:399–408.
    • (2005) Int J Impotence Res , vol.17 , pp. 399-408
    • Bolour, S.1    Braunstein, G.2
  • 44
    • 79955634485 scopus 로고    scopus 로고
    • Cardiovascular and cancer safety of testosterone in women
    • Davis SR. Cardiovascular and cancer safety of testosterone in women. Curr Opin Endocrinol Diabet Obes 2011;18:198–203.
    • (2011) Curr Opin Endocrinol Diabet Obes , vol.18 , pp. 198-203
    • Davis, S.R.1
  • 45
    • 29144469309 scopus 로고    scopus 로고
    • Adverse events associated with testosterone replacement in middle-aged and older men: A meta-analysis of randomized, placebo-controlled trials
    • Calof OM, Singh AB, Lee ML, et al. Adverse events associated with testosterone replacement in middle-aged and older men: A meta-analysis of randomized, placebo-controlled trials. J Gerontol Ser A Biol Sci Med Sci 2005;60:1451–1457.
    • (2005) J Gerontol Ser A Biol Sci Med Sci , vol.60 , pp. 1451-1457
    • Calof, O.M.1    Singh, A.B.2    Lee, M.L.3
  • 46
    • 33746825578 scopus 로고    scopus 로고
    • Extraprostatic complications of testosterone replacement therapy
    • (Proceedings)
    • Volpi R, Coiro V, Chiodera P, et al. Extraprostatic complications of testosterone replacement therapy. J Endocrinol Investig 2005;28:(11 Suppl Proceedings):75–77.
    • (2005) J Endocrinol Investig , vol.28 , pp. 75-77
    • Volpi, R.1    Coiro, V.2    Chiodera, P.3
  • 47
    • 85009767819 scopus 로고    scopus 로고
    • Secondary polycythemia and the risk of venous thromboembolism
    • Bhatt VR. Secondary polycythemia and the risk of venous thromboembolism. J Clin Med Res 2014;6:395–397.
    • (2014) J Clin Med Res , vol.6 , pp. 395-397
    • Bhatt, V.R.1
  • 48
    • 84979846293 scopus 로고    scopus 로고
    • Erythrocytosis and polycythemia secondary to testosterone replacement therapy in the aging male
    • Jones SD, Dukovac T, Sangkum P, et al. Erythrocytosis and polycythemia secondary to testosterone replacement therapy in the aging male. Sex Med Rev 2015;3:101–112.
    • (2015) Sex Med Rev , vol.3 , pp. 101-112
    • Jones, S.D.1    Dukovac, T.2    Sangkum, P.3
  • 49
    • 77954394453 scopus 로고    scopus 로고
    • Clinical review 1: Adverse effects of testosterone therapy in adult men: A systematic review and meta-analysis
    • Fernandez-Balsells MM, Murad MH, Lane M, et al. Clinical review 1: Adverse effects of testosterone therapy in adult men: A systematic review and meta-analysis. J Clin Endocrinol Metab 2010;95:2560–2575.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 2560-2575
    • Fernandez-Balsells, M.M.1    Murad, M.H.2    Lane, M.3
  • 50
    • 40849086206 scopus 로고    scopus 로고
    • Effects of graded doses of testosterone on erythropoiesis in healthy young and older men
    • Coviello AD, Kaplan B, Lakshman KM, et al. Effects of graded doses of testosterone on erythropoiesis in healthy young and older men. J Clin Endocrinol Metab 2008;93:914–919.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 914-919
    • Coviello, A.D.1    Kaplan, B.2    Lakshman, K.M.3
  • 51
    • 77954409942 scopus 로고    scopus 로고
    • Testosterone therapy in men with androgen deficiency syndromes: An endocrine society clinical practice guideline
    • Bhasin S, Cunningham GR, Hayes FJ, et al. Testosterone therapy in men with androgen deficiency syndromes: An endocrine society clinical practice guideline. J Clin Endocrinol Metab 2010;95:2536–2559.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 2536-2559
    • Bhasin, S.1    Cunningham, G.R.2    Hayes, F.J.3
  • 52
    • 84871746842 scopus 로고    scopus 로고
    • Cardiovascular events and intensity of treatment in polycythemia vera
    • Marchioli R, Finazzi G, Specchia G, et al. Cardiovascular events and intensity of treatment in polycythemia vera. N Engl J Med 2013;368:22–33.
    • (2013) N Engl J Med , vol.368 , pp. 22-33
    • Marchioli, R.1    Finazzi, G.2    Specchia, G.3
  • 53
    • 0346727336 scopus 로고    scopus 로고
    • Efficacy and safety of low-dose aspirin in polycythemia vera
    • Landolfi R, Marchioli R, Kutti J, et al. Efficacy and safety of low-dose aspirin in polycythemia vera. N Engl J Med 2004;350:114–124.
    • (2004) N Engl J Med , vol.350 , pp. 114-124
    • Landolfi, R.1    Marchioli, R.2    Kutti, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.