Field evaluation of a high throughput loop mediated isothermal amplification test for the detection of asymptomatic plasmodium infections in Zanzibar

PLoS ONE

Volumn 12, Issue 1, 2017, Pages

  Aydin Schmidt, Berit ^a,b   Morris, Ulrika ^a   Ding, Xavier C ^c   Jovel, Irina ^a   Msellem, Mwinyi I ^d   Bergman, Daniel ^a   Islam, Atiqul ^a   Ali, Abdullah S ^d   Polley, Spencer ^e   Gonzalez, Iveth J ^c   Martensson, Andreas ^f   Björkman, Anders ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c FOUNDATION FOR INNOVATIVE NEW DIAGNOSTICS   (Switzerland)

^d and Children   (Tanzania)

^e HOSPITAL FOR TROPICAL DISEASES   (United Kingdom)

^f UPPSALA UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ARTEMISININ;

ADOLESCENT; ADULT; AGED; ARTICLE; ASYMPTOMATIC INFECTION; CHILD; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; DNA EXTRACTION; FEMALE; HUMAN; INFANT; INTERMETHOD COMPARISON; LAMP SYSTEM; LOOP MEDIATED ISOTHERMAL AMPLIFICATION; MAJOR CLINICAL STUDY; MALARIA; MALARIA FALCIPARUM; MALARIA RAPID TEST; MALE; MIXED INFECTION; PARASITE IDENTIFICATION; PARASITE PREVALENCE; PLASMODIUM FALCIPARUM; PLASMODIUM MALARIAE; PLASMODIUM MALARIAE INFECTION; PREDICTIVE VALUE; REAL TIME POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SENSITIVITY AND SPECIFICITY; TANZANIA; ASYMPTOMATIC INFECTIONS; CROSS-SECTIONAL STUDY; EVALUATION STUDY; GENETICS; ISOLATION AND PURIFICATION; MIDDLE AGED; MOLECULAR DIAGNOSIS; NEWBORN; NUCLEIC ACID AMPLIFICATION; PARASITOLOGY; PLASMODIUM; PRESCHOOL CHILD; PREVALENCE; PROCEDURES; VERY ELDERLY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ASYMPTOMATIC INFECTIONS; CHILD; CHILD, PRESCHOOL; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; INFANT; INFANT, NEWBORN; MALARIA; MALE; MIDDLE AGED; MOLECULAR DIAGNOSTIC TECHNIQUES; NUCLEIC ACID AMPLIFICATION TECHNIQUES; PLASMODIUM; PREVALENCE; REAL-TIME POLYMERASE CHAIN REACTION; TANZANIA; YOUNG ADULT;

EID: 85009749006     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0169037     Document Type: Article

References (26)

1. Karl S, Gurarie D, Zimmerman PA, King CH, St Pierre TG, Davis TM (2011) A sub-microscopic gametocyte reservoir can sustain malaria transmission. PLoS One 6: e20805. doi: 10.1371/journal.pone. 0020805 PMID: 21695129
2. Manjurano A, Okell L, Lukindo T, Reyburn H, Olomi R, Roper C, et al. (2011) Association of sub-microscopic malaria parasite carriage with transmission intensity in north-eastern Tanzania. Malaria journal 10: 370. doi: 10.1186/1475-2875-10-370 PMID: 22177014
3. Wu L, van den Hoogen LL, Slater H, Walker PG, Ghani AC, Drakeley CJ, et al. (2015) Comparison of diagnostics for the detection of asymptomatic Plasmodium falciparum infections to inform control and elimination strategies. Nature 528: S86-93. doi: 10.1038/nature16039 PMID: 26633770
4. Okell LC, Bousema T, Griffin JT, Ouedraogo AL, Ghani AC, Drakeley CJ (2012) Factors determining the occurrence of submicroscopic malaria infections and their relevance for control. Nature communications 3: 1237. doi: 10.1038/ncomms2241 PMID: 23212366
5. The malERA Consultative Group (2011) A research agenda for malaria eradication: diagnoses and diagnostics. PLoS medicine 8: e1000396. doi: 10.1371/journal.pmed.1000396 PMID: 21311583
6. Britton S, Cheng Q, Sutherland CJ, McCarthy JS (2015) A simple, high-throughput, colourimetric, field applicable loop-mediated isothermal amplification (HtLAMP) assay for malaria elimination. Malaria journal 14: 335. doi: 10.1186/s12936-015-0848-3 PMID: 26315027
7. Han ET (2013) Loop-mediated isothermal amplification test for the molecular diagnosis of malaria. Expert Rev Mol Diagn 13: 205-218. doi: 10.1586/erm.12.144 PMID: 23477559
8. Hopkins H, Gonzalez IJ, Polley SD, Angutoko P, Ategeka J, Asiimwe C, et al. (2013) Highly sensitive detection of malaria parasitemia in a malaria-endemic setting: performance of a new loop-mediated isothermal amplification kit in a remote clinic in Uganda. The Journal of infectious diseases 208: 645-652. doi: 10.1093/infdis/jit184 PMID: 23633405
9. WHO (2014) WHO evidence group on malaria diagnosis in low transmission settings,. http://www.who. int/malaria/publications/atoz/policy-brief-diagnosis-low-transmission-settings/en/.
10. Cook J, Aydin-Schmidt B, Gonzalez IJ, Bell D, Edlund E, Nassor MH, et al. (2015) Loop-mediated isothermal amplification (LAMP) for point-of-care detection of asymptomatic low-density malaria parasite carriers in Zanzibar. Malaria journal 14: 43. doi: 10.1186/s12936-015-0573-y PMID: 25627037
11. Morris U, Khamis M, Aydin-Schmidt B, Abass AK, Msellem MI, Nassor MH, et al. (2015) Field deployment of loop-mediated isothermal amplification for centralized mass-screening of asymptomatic malaria in Zanzibar: A pre-elimination setting. Malaria journal 14: 205. doi: 10.1186/s12936-015-0731-2 PMID: 25982190
12. Perera R, Gonzalez IJ, Ding X, et al (2016) Clinical performance of high throughput loop-mediated isothermal amplification for detection of malaria. PlosOne
13. Morris U, Xu W, Msellem MI, Schwartz A, Abass A, Shakely D, et al. (2015) Characterising temporal trends in asymptomatic Plasmodium infections and transporter polymorphisms during transition from high to low transmission in Zanzibar, 2005-2013. Infection, genetics and evolution: journal of molecular epidemiology and evolutionary genetics in infectious diseases 33: 110-117. doi: 10.1016/j.meegid. 2015.04.018 PMID: 25917493
14. Polley SD, Bell D, Oliver J, Tully F, Perkins MD, Chiodini PL, et al. (2015) The design and evaluation of a shaped filter collection device to sample and store defined volume dried blood spots from finger pricks. Malaria journal 14: 45 doi: 10.1186/s12936-015-0558-x PMID: 25652763
15. FIND Ffind (2012) Manual of standard Operating Procedures for malaria LAMP,. http://www. finddiagnostics.org/export/sites/default/programs/malaria-afs/docs/SOPs-LAMP-Malaria-AUG12.pdf.
16. Aydin-Schmidt B, Xu W, Gonzalez IJ, Polley SD, Bell D, Shakely D, et al. (2014) Loop mediated isothermal amplification (LAMP) accurately detects malaria DNA from filter paper blood samples of low density parasitaemias. PloS one 9: e103905. doi: 10.1371/journal.pone.0103905 PMID: 25105591
17. Polley SD, Mori Y, Watson J, Perkins MD, Gonzalez IJ, Notomi T, et al. (2010) Mitochondrial DNA targets increase sensitivity of malaria detection using loop-mediated isothermal amplification. Journal of clinical microbiology 48: 2866-2871. doi: 10.1128/JCM.00355-10 PMID: 20554824
18. Wooden J, Kyes S, Sibley CH (1993) PCR and strain identification in Plasmodium falciparum. Parasitol Today 9: 303-305. PMID: 15463789
19. Xu W, Morris U, Aydin-Schmidt B, Msellem MI, Shakely D, Petzold M, et al. (2015) SYBR Green realtime PCR-RFLP assay targeting the plasmodium cytochrome B gene-a highly sensitive molecular tool for malaria parasite detection and species determination. PloS one 10: e0120210. doi: 10.1371/journal. pone.0120210 PMID: 25774805
20. Kamau E, Alemayehu S, Feghali KC, Saunders D, Ockenhouse CF (2013) Multiplex qPCR for detection and absolute quantification of malaria. PloS one 8: e71539. doi: 10.1371/journal.pone.0071539 PMID: 24009663
21. NIBSC WIS Plasmodium falciparum DNA for NAT assays https://www.nibsc.org/documents/ifu/04-176. pdf.
22. Bossuyt PM, Reitsma JB, Bruns DE, Gatsonis CA, Glasziou PP, Irwig L, et al. (2015) STARD 2015: an updated list of essential items for reporting diagnostic accuracy studies. BMJ 351: h5527. doi: 10.1136/bmj.h5527 PMID: 26511519
23. Costa DC, Madureira AP, Amaral LC, Sanchez BA, Gomes LT, Fontes CJ, et al. (2014) Submicroscopic malaria parasite carriage: how reproducible are polymerase chain reaction-based methods? Mem Inst Oswaldo Cruz 109: 21-28. doi: 10.1590/0074-0276140102 PMID: 24626306
24. Singh B, Bobogare A, Cox-Singh J, Snounou G, Abdullah MS, Rahman HA (1999) A genus-and species-specific nested polymerase chain reaction malaria detection assay for epidemiologic studies. The American journal of tropical medicine and hygiene 60: 687-692. PMID: 10348249
25. Oriero EC, Okebe J, Jacobs J, Van Geertruyden JP, Nwakanma D, D'Alessandro U (2015) Diagnostic performance of a novel loop-mediated isothermal amplification (LAMP) assay targeting the apicoplast genome for malaria diagnosis in a field setting in sub-Saharan Africa. Malaria journal 14: 396. doi: 10.1186/s12936-015-0926-6 PMID: 26450599
26. Vallejo AF, Martinez NL, Gonzalez IJ, Arevalo-Herrera M, Herrera S (2015) Evaluation of the loop mediated isothermal DNA amplification (LAMP) kit for malaria diagnosis in P. vivax endemic settings of Colombia. PLoS neglected tropical diseases 9: e3453. doi: 10.1371/journal.pntd.0003453 PMID: 25569550