Nutritional-rich and stress-tolerant crops by saccharopine pathway manipulation

Food and Energy Security

Volumn 1, Issue 2, 2012, Pages 141-147

  Arruda, Paulo ^a   Neshich, Izabella Pena ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Amino acid metabolism; Lysine catabolism; Nutritional enhancement; Saccharopine pathway; Stress tolerance

Indexed keywords

EID: 85009474916     PISSN: None     EISSN: 20483694     Source Type: Journal    
DOI: 10.1002/fes3.9     Document Type: Review

References (49)

1. Anderson, O. D., D. Coleman-Derr, Y. Q. Gu, and S. Heath. 2010. Structural and transcriptional analysis of plant genes encoding the bifunctional lysine ketoglutarate reductase saccharopine dehydrogenase enzyme. BMC Plant Biol. 10:113
2. Angelovici, R., A. Fait, X. Zhu, J. Szymanski, E. Feldmesser, A. R. Fernie, et al. 2009. Deciphering transcriptional and metabolic networks associated with lysine metabolism during Arabidopsis seed development. Plant Physiol. 151:2058-2072
3. Angelovici, R., F. Aaron, A. R. Fernie, and G. Galili. 2011. A seed high-lysine trait is negatively associated with the TCA cycle and slows down Arabidopsis seed germination. New Phytol. 189:148-159
4. Arruda, P., and W. J. Silva. 1983. Lysine-ketoglutaric acid reductase activity in maize: its possible role on lysine metabolism of developing endosperm. Phytochemistry 22:206-208
5. Arruda, P., E. L. Kemper, F. Papes, and A. Leite. 2000. Regulation of lysine catabolism in higher plants. Trends Plant Sci. 5:324-330
6. Avin-Wittenberg, T., and G. Galili. 2012. Metabolism: amino acid regulatory wisdom. Nat. Chem. Biol. 8:23-24
7. Azevedo, R. A., and P. Arruda. 2010. High-lysine maize: the key discoveries that have made it possible. Amino Acids 39:979-989
8. Azevedo, R. A., P. Arruda, W. L. Turner, and P. J. Lea. 1997. The biosynthesis and metabolism of the aspartate derived amino acids in higher plants. Phytochemistry 46:395-419
9. Battur, B., D. Boldbaatar, R. Umemiya-Shirafuji, M. Liao, B. Battsetseg, D. Taylor, et al. 2009. LKR/SDH plays important roles throughout the tick life cycle including a long starvation period. PLoS One 4:e7136
10. Bright, S. W. J., J. S. H. Kueh, J. Franklin, S. E. Rognes, and B. J. Miflin. 1982. Two genes for threonine accumulation in barley seeds. Nature 299:278-279
11. Brocker, C., N. Lassen, T. Estey, A. Pappa, M. Cantore, V. V. Orlova, et al. 2010. Aldehyde dehydrogenase 7A1 (ALDH7A1) is a novel enzyme involved in cellular defense against hyperosmotic stress. J. Biol. Chem. 285:18452-18463
12. Chad, B., M. Cantore, P. Faillib, and V. Vasiliou. 2011. Aldehyde dehydrogenase 7A1 (ALDH7A1) attenuates reactive aldehyde and oxidative stress induced cytotoxicity. Chem. Biol. Interact. 191:269-277
13. Chaturvedi, R., K. Bansal, Y. Narayana, N. Kapoor, N. Sukumar, S. K. Togarsimalemath, et al. 2010. The multifunctional PE_PGRS11 protein from Mycobacterium tuberculosis plays a role in regulating resistance to oxidative stress. J. Biol. Chem. 285:30389-30403
14. Deleu, C., M. Cousrtaut, M. F. Niogret, and F. Larher. 1999. Three new osmotic stress-regulated cDNAs identified by differential display polymerase chain reaction in rapeseed leaf discs. Plant Cell Environ. 22:979-988
15. Eduard, A. S., and C. Jakobs. 2010. Metabolism of lysine in α-aminoadipic semialdehyde dehydrogenase-deficient fibroblasts: evidence for an alternative pathway of pipecolic acid formation. FEBS Lett. 584:181-186
16. Falco, S. C., T. Guida, M. Locke, J. Mauvais, C. Sanders, R. T. Ward, et al. 1995. Transgenic canola and soybean seeds with increased lysine. Biotechnology 13:577-582
17. Ferreira, R. R., V. A. Varisi, L. W. Meinhardt, P. J. Lea, and R. A. Azevedo. 2005. Are high-lysine cereal crops still a challenge? Braz. J. Med. Biol. Res. 38:985-994
18. Fong, W. P., C. H. Cheng, and W. K. Tang. 2006. Antiquitin, a relatively unexplored member in the superfamily of aldehyde dehydrogenases with diversified physiological functions. Cell. Mol. Life Sci. 63:2881-2885
19. Frizzi, A., S. Huang, L. A. Gilbertson, T. A. Armstrong, M. H. Luethy, and T. M. Malvar. 2008. Modifying lysine biosynthesis and catabolism in corn with a single bifunctional expression/silencing transgene cassette. Plant Biotechnol. J. 6:13-21
20. Galili, G. 1995. Regulation of lysine and threonine synthesis. Plant Cell 7:899-906
21. Gaziola, S. A., C. M. Teixeira, J. Lugli, L. Sodek, and R. A. Azevedo. 1997. The enzymology of lysine catabolism in rice seeds-isolation, characterization, and regulatory properties of a lysine 2-oxoglutarate reductase/saccharopine dehydrogenase bifunctional polypeptide. Eur. J. Biochem. 247:364-371
22. Gonçalves-Butruille, M., P. Szajner, E. Torigoi, A. Leite, and P. Arruda. 1996. Purification and characterization of the bifunctional enzyme lysine-ketoglutarate reductasesaccharopine dehydrogenase from maize. Plant Physiol. 110:765-771
23. Gouesbet, G., C. Blanco, J. Hamelin, and T. Bernard. 1992. Osmotic adjustment in Brevibacterium ammonkgenes: pipecolic acid accumulation at elevated osmolalities. Microbiol. 138:959-965
24. Guerrero, F. D., J. T. Jones, and J. E. Mullet. 1990. Turgorresponsive gene transcription and RNA levels increase rapidly when pea shoots are wilted. Sequence and expression of three inducible genes. Plant Mol. Biol. 15:11-26
25. Houmard, N. M., J. L. Mainville, C. P. Bonin, S. Huang, M. H. Luethy, and T. M. Malvar. 2007. High-lysine corn generated by endosperm-specific suppression of lysine catabolism using RNAi. Plant Biotechnol. J. 5:605-614
26. Kawakatsu, T., and F. Takaiwa. 2010. Differences in transcriptional regulatory mechanisms functioning for free lysine content and seed storage protein accumulation in rice grain. Plant Cell Physiol. 51:1964-1974
27. Kemper, E. L., G. C. Neto, F. Papes, K. C. Moraes, A. Leite, and P. Arruda. 1999. The role of Opaque2 on the control of lysine degrading activities in developing maize endosperm. Plant Cell 11:1981-1994
28. Kirch, H. H., S. Schlingensiepen, S. Kotchoni, R. Sunkar, and D. Bartels. 2005. Detailed expression analysis of selected genes of the aldehyde dehydrogenase (ALDH) gene superfamily in Arabidopsis thaliana. Plant Mol. Biol. 57:315-332
29. Kotchoni, S. O., C. Kuhns, A. Ditzer, H. H. Kirch, and D. Bartels. 2006. Over-expression of different aldehyde dehydrogenase genes in Arabidopsis thaliana confers tolerance to abiotic stress and protects plants against lipid peroxidation and oxidative stress. Plant Cell Environ. 29:1033-1048
30. Lee, P., W. Kuhl, T. Gelbart, T. Kamimura, C. West, and E. Beutler. 1994. Homology between a human protein and a protein of the green garden pea. Genomics 21:371-378
31. Lucas, D. M., M. L. Taylor, G. F. Hartnell, M. A. Nemeth, K. C. Glenn, and S. W. Davis. 2007. Broiler performance and carcass characteristics when fed diets containing lysine maize (LY038 or LY038 9 MON 810), control, or Conventional Reference Maize. Poult. Sci. 86:2152-2161
32. Markovitz, P. J., and D. T. Chuang. 1987. The bifunctional aminoadipic semialdehyde synthase in lysine degradation. J. Biol. Chem. 262:9353-9358
33. Mills, P. B., E. Struys, C. Jakobs, B. Plecko, P. Baxter, M. Baumgartner, et al. 2006. Mutations in antiquitin in individuals with pyridoxine-dependent seizures. Nat. Med. 12:307-309
34. Moulin, M., C. Deleu, and F. Larher. 2000. L-Lysine catabolism is osmo-regulated at the level of lysineketoglutarate reductase and saccharopine dehydrogenase in rapeseed leaf discs. Plant Physiol. Biochem. 38:577-585
35. Moulin, M., C. Deleu, F. Larher, and A. Bouchereau. 2006. The lysine-ketoglutarate reductase-saccharopine dehydrogenase is involved in the osmo-induced synthesis of pipecolic acid in rapeseed leaf tissues. Plant Physiol. Biochem. 44:474-482
36. Nanjo, T., M. Kobayashi, Y. Yoshiba, Y. Sanada, K. Wada, H. Tsukaya, et al. 1999. Biological functions of proline in morphogenesis and osmotolerance revealed in antisense transgenic Arabidopsis thaliana. Plant J. 18:185-193
37. Pitman, M., and A. Lauchli. 2004. Global impact of salinity and agricultural ecosystems. Pp. 3-20 in A. Lauchli and U. Luttge, eds. Salinity: environment-plants-molecules. Kluwer Academic Publishers, NY
38. Reyes, A. R., C. P. Bonin, N. M. Houmard, S. Huang, and T. M. Malvar. 2009. Genetic manipulation of lysine catabolism in maize kernels. Plant Mol. Biol. 69:81-89
39. Rodrigues, S. M., M. O. Andrade, A. P. S. Gomes, F. M. DaMatta, M. C. Baracat-Pereira, and E. P. B. Fontes. 2006. Arabidopsis and tobacco plants ectopically expressing the soybean antiquitin-like ALDH7 gene display enhanced tolerance to drought, salinity, and oxidative stress. J. Exp. Bot. 57:1909-1918
40. Roosens, N. H., T. T. Thu, H. M. Iskandar, and M. Jacobs. 1998. Isolation of the ornithine-delta-aminotransferase cDNA and effect of salt stress on its expression in Arabidopsis thaliana. Plant Physiol. 117:263-271
41. Roxas, V. P., S. A. Lodhi, D. K. Garrett, J. R. Mahan, and R. D. Allen. 2000. Stress tolerance in transgenic tobacco seedlings that overexpress glutathione S-transferase/ glutathione peroxidase. Plant Cell Physiol. 41:1229-1234
42. Schmidt, R. J., F. A. Burr, M. J. Aukerman, and B. Burr. 1990. Maize regulatory gene opaque-2 encodes a protein with a leucine-zipper motif that binds to zein DNA. Proc. Natl. Acad. Sci. USA 87:46-50
43. Serrano, G. C., T. R. Silva-Figueira, E. Kiyota, N. Zanata, and P. Arruda. 2012. Lysine degradation through the saccharopine pathway in bacteria: LKR and SDH in bacteria and its relationship to the plant and animal enzymes. FEBS Lett. 586:905-911
44. Shewry, P. R. 2007. Improving the protein content and composition of cereal grain. J. Cereal Sci. 46:239-250
45. Shewry, P. R., and R. Casey. 1999. Seed proteins. Pp. 1-10 in R. Casey and P. R. Shewry, eds. Seed proteins. Kluwer Academic Publishers, Dordrecht, The Netherlands
46. Shin, J. H., S. R. Kim, and G. An. 2009. Rice aldehyde dehydrogenase7 is needed for seed maturation and viability. Plant Physiol. 149:905-915
47. Skvorak, A. B., N. G. Robertson, Y. Yin, S. Weremowicz, H. Her, F. R. Bieber, et al. 1997. An ancient conserved gene expressed in the human inner ear: identification, expression analysis and chromosomal mapping of human and mouse antiquitin (ATQ1). Genomics 46:191-199
48. Tosi, P., C. S. Gritsch, J. He, and P. R. Shewry. 2011. Distribution of gluten proteins in bread wheat (Triticum aestivum) grain. Ann. Bot. 108:23-35
49. Zhang, H., H. Bing, T. Wang, S. Chen, H. Li, Y. Zhang, et al. 2012. Mechanisms of plant salt response: insights from proteomics. J. Proteome Res. 11:49-67