-
1
-
-
85016384989
-
-
Cancer of the endometrium. SEER Stat Fact Sheets;.
-
1 National Cancer Institute. Cancer of the endometrium. SEER Stat Fact Sheets; 2015.
-
(2015)
-
-
-
2
-
-
85016371949
-
-
Uterine neoplasms, version 2.2015.;.
-
2 National Comprehensive Cancer Network. Uterine neoplasms, version 2.2015. http://www.nccn.org/professionals/physician_gls/pdf/uterine.pdf; 2015.
-
(2015)
-
-
-
3
-
-
37549061012
-
Current issues in the management of endometrial cancer
-
3 Bakkum-Gamez, J.N., Gonzalez-Bosquet, J., Laack, N.N., Mariani, A., Dowdy, S.C., Current issues in the management of endometrial cancer. Mayo Clin Proc 83:1 (2008), 97–112.
-
(2008)
Mayo Clin Proc
, vol.83
, Issue.1
, pp. 97-112
-
-
Bakkum-Gamez, J.N.1
Gonzalez-Bosquet, J.2
Laack, N.N.3
Mariani, A.4
Dowdy, S.C.5
-
4
-
-
84899849944
-
Past, present, and future of hormonal therapy in recurrent endometrial cancer
-
4 Carlson, M.J., Thiel, K.W., Leslie, K.K., Past, present, and future of hormonal therapy in recurrent endometrial cancer. Int J Womens Health 6 (2014), 429–435.
-
(2014)
Int J Womens Health
, vol.6
, pp. 429-435
-
-
Carlson, M.J.1
Thiel, K.W.2
Leslie, K.K.3
-
5
-
-
0027992159
-
Microsatellite instability in sporadic endometrial carcinoma
-
5 Duggan, B.D., Felix, J.C., Muderspach, L.I., Tourgeman, D., Zheng, J., Shibata, D., Microsatellite instability in sporadic endometrial carcinoma. J Natl Cancer Inst 86:16 (1994), 1216–1221.
-
(1994)
J Natl Cancer Inst
, vol.86
, Issue.16
, pp. 1216-1221
-
-
Duggan, B.D.1
Felix, J.C.2
Muderspach, L.I.3
Tourgeman, D.4
Zheng, J.5
Shibata, D.6
-
6
-
-
0027366916
-
Genetic instability of microsatellites in endometrial carcinoma
-
6 Risinger, J.I., Berchuck, A., Kohler, M.F., Watson, P., Lynch, H.T., Boyd, J., Genetic instability of microsatellites in endometrial carcinoma. Cancer Res 53:21 (1993), 5100–5103.
-
(1993)
Cancer Res
, vol.53
, Issue.21
, pp. 5100-5103
-
-
Risinger, J.I.1
Berchuck, A.2
Kohler, M.F.3
Watson, P.4
Lynch, H.T.5
Boyd, J.6
-
7
-
-
84873059633
-
Endometrial carcinoma: molecular alterations involved in tumor development and progression
-
7 Yeramian, A., Moreno-Bueno, G., Dolcet, X., et al. Endometrial carcinoma: molecular alterations involved in tumor development and progression. Oncogene 32:4 (2013), 403–413.
-
(2013)
Oncogene
, vol.32
, Issue.4
, pp. 403-413
-
-
Yeramian, A.1
Moreno-Bueno, G.2
Dolcet, X.3
-
8
-
-
52049086201
-
Inhibition of activated fibroblast growth factor receptor 2 in endometrial cancer cells induces cell death despite PTEN abrogation
-
8 Byron, S.A., Gartside, M.G., Wellens, C.L., et al. Inhibition of activated fibroblast growth factor receptor 2 in endometrial cancer cells induces cell death despite PTEN abrogation. Cancer Res 68:17 (2008), 6902–6907.
-
(2008)
Cancer Res
, vol.68
, Issue.17
, pp. 6902-6907
-
-
Byron, S.A.1
Gartside, M.G.2
Wellens, C.L.3
-
9
-
-
84896715470
-
Targeting molecular pathways in endometrial cancer: a focus on the FGFR pathway
-
9 Lee, P.S., Secord, A.A., Targeting molecular pathways in endometrial cancer: a focus on the FGFR pathway. Cancer Treat Rev 40:4 (2014), 507–512.
-
(2014)
Cancer Treat Rev
, vol.40
, Issue.4
, pp. 507-512
-
-
Lee, P.S.1
Secord, A.A.2
-
10
-
-
84872294755
-
Fibroblast growth factor receptor inhibition synergizes with paclitaxel and doxorubicin in endometrial cancer cells
-
10 Byron, S.A., Loch, D.C., Pollock, P.M., Fibroblast growth factor receptor inhibition synergizes with paclitaxel and doxorubicin in endometrial cancer cells. Int J Gynecol Cancer 22:9 (2012), 1517–1526.
-
(2012)
Int J Gynecol Cancer
, vol.22
, Issue.9
, pp. 1517-1526
-
-
Byron, S.A.1
Loch, D.C.2
Pollock, P.M.3
-
11
-
-
47249122523
-
Drug-sensitive FGFR2 mutations in endometrial carcinoma
-
11 Dutt, A., Salvesen, H.B., Chen, T.H., et al. Drug-sensitive FGFR2 mutations in endometrial carcinoma. Proc Natl Acad Sci U S A 105:25 (2008), 8713–8717.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.25
, pp. 8713-8717
-
-
Dutt, A.1
Salvesen, H.B.2
Chen, T.H.3
-
12
-
-
34250829395
-
Frequent activating FGFR2 mutations in endometrial carcinomas parallel germline mutations associated with craniosynostosis and skeletal dysplasia syndromes
-
12 Pollock, P.M., Gartside, M.G., Dejeza, L.C., et al. Frequent activating FGFR2 mutations in endometrial carcinomas parallel germline mutations associated with craniosynostosis and skeletal dysplasia syndromes. Oncogene 26:50 (2007), 7158–7162.
-
(2007)
Oncogene
, vol.26
, Issue.50
, pp. 7158-7162
-
-
Pollock, P.M.1
Gartside, M.G.2
Dejeza, L.C.3
-
13
-
-
79959972313
-
Endometrial cancer: what is new in adjuvant and molecularly targeted therapy?
-
13 Zagouri, F., Bozas, G., Kafantari, E., et al. Endometrial cancer: what is new in adjuvant and molecularly targeted therapy?. Obstet Gynecol Int, 2010, 2010, 749579.
-
(2010)
Obstet Gynecol Int
, vol.2010
, pp. 749579
-
-
Zagouri, F.1
Bozas, G.2
Kafantari, E.3
-
14
-
-
77956794025
-
Genetics of endometrial cancers
-
14 Okuda, T., Sekizawa, A., Purwosunu, Y., et al. Genetics of endometrial cancers. Obstet Gynecol Int, 2010, 2010, 984013.
-
(2010)
Obstet Gynecol Int
, vol.2010
, pp. 984013
-
-
Okuda, T.1
Sekizawa, A.2
Purwosunu, Y.3
-
15
-
-
0034651530
-
The frequency of p53, K-ras mutations, and microsatellite instability differs in uterine endometrioid and serous carcinoma: evidence of distinct molecular genetic pathways
-
15 Lax, S.F., Kendall, B., Tashiro, H., Slebos, R.J., Hedrick, L., The frequency of p53, K-ras mutations, and microsatellite instability differs in uterine endometrioid and serous carcinoma: evidence of distinct molecular genetic pathways. Cancer 88:4 (2000), 814–824.
-
(2000)
Cancer
, vol.88
, Issue.4
, pp. 814-824
-
-
Lax, S.F.1
Kendall, B.2
Tashiro, H.3
Slebos, R.J.4
Hedrick, L.5
-
16
-
-
84877254190
-
Integrated genomic characterization of endometrial carcinoma
-
16 Cancer Genome Atlas Research Network, Kandoth, C., Schultz, N., et al. Integrated genomic characterization of endometrial carcinoma. Nature 497:7447 (2013), 67–73.
-
(2013)
Nature
, vol.497
, Issue.7447
, pp. 67-73
-
-
Cancer Genome Atlas Research Network1
Kandoth, C.2
Schultz, N.3
-
17
-
-
79251501315
-
Fibroblast growth factors: from molecular evolution to roles in development, metabolism and disease
-
17 Itoh, N., Ornitz, D.M., Fibroblast growth factors: from molecular evolution to roles in development, metabolism and disease. J Biochem 149:2 (2011), 121–130.
-
(2011)
J Biochem
, vol.149
, Issue.2
, pp. 121-130
-
-
Itoh, N.1
Ornitz, D.M.2
-
18
-
-
79955667838
-
Targeting mutant fibroblast growth factor receptors in cancer
-
18 Greulich, H., Pollock, P.M., Targeting mutant fibroblast growth factor receptors in cancer. Trends Mol Med 17:5 (2011), 283–292.
-
(2011)
Trends Mol Med
, vol.17
, Issue.5
, pp. 283-292
-
-
Greulich, H.1
Pollock, P.M.2
-
19
-
-
61649100307
-
The FGF family: biology, pathophysiology and therapy
-
19 Beenken, A., Mohammadi, M., The FGF family: biology, pathophysiology and therapy. Nat Rev Drug Discov 8:3 (2009), 235–253.
-
(2009)
Nat Rev Drug Discov
, vol.8
, Issue.3
, pp. 235-253
-
-
Beenken, A.1
Mohammadi, M.2
-
20
-
-
84868260259
-
Alternative splicing of fibroblast growth factor receptor IgIII loops in cancer
-
20 Holzmann, K., Grunt, T., Heinzle, C., et al. Alternative splicing of fibroblast growth factor receptor IgIII loops in cancer. J Nucleic Acids, 2012, 2012, 950508.
-
(2012)
J Nucleic Acids
, vol.2012
, pp. 950508
-
-
Holzmann, K.1
Grunt, T.2
Heinzle, C.3
-
21
-
-
84876048479
-
Fibroblast growth factor receptor inhibitors as a cancer treatment: from a biologic rationale to medical perspectives
-
21 Dieci, M.V., Arnedos, M., Andre, F., Soria, J.C., Fibroblast growth factor receptor inhibitors as a cancer treatment: from a biologic rationale to medical perspectives. Cancer Discov 3:3 (2013), 264–279.
-
(2013)
Cancer Discov
, vol.3
, Issue.3
, pp. 264-279
-
-
Dieci, M.V.1
Arnedos, M.2
Andre, F.3
Soria, J.C.4
-
22
-
-
33344455174
-
Autophosphorylation of FGFR1 kinase is mediated by a sequential and precisely ordered reaction
-
22 Furdui, C.M., Lew, E.D., Schlessinger, J., Anderson, K.S., Autophosphorylation of FGFR1 kinase is mediated by a sequential and precisely ordered reaction. Mol Cell 21:5 (2006), 711–717.
-
(2006)
Mol Cell
, vol.21
, Issue.5
, pp. 711-717
-
-
Furdui, C.M.1
Lew, E.D.2
Schlessinger, J.3
Anderson, K.S.4
-
23
-
-
0026641249
-
Point mutation in FGF receptor eliminates phosphatidylinositol hydrolysis without affecting mitogenesis
-
23 Mohammadi, M., Dionne, C.A., Li, W., et al. Point mutation in FGF receptor eliminates phosphatidylinositol hydrolysis without affecting mitogenesis. Nature 358:6388 (1992), 681–684.
-
(1992)
Nature
, vol.358
, Issue.6388
, pp. 681-684
-
-
Mohammadi, M.1
Dionne, C.A.2
Li, W.3
-
24
-
-
0032559228
-
Sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the drosophila airways
-
24 Hacohen, N., Kramer, S., Sutherland, D., Hiromi, Y., Krasnow, M.A., Sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the drosophila airways. Cell 92:2 (1998), 253–263.
-
(1998)
Cell
, vol.92
, Issue.2
, pp. 253-263
-
-
Hacohen, N.1
Kramer, S.2
Sutherland, D.3
Hiromi, Y.4
Krasnow, M.A.5
-
25
-
-
0038476592
-
Self-inhibits fibroblast growth factor signaling by inhibiting FGFR1 tyrosine phosphorylation and subsequent ERK activation
-
25 Kovalenko, D., Yang, X., Nadeau, R.J., Harkins, L.K., Friesel, R., Self-inhibits fibroblast growth factor signaling by inhibiting FGFR1 tyrosine phosphorylation and subsequent ERK activation. J Biol Chem 278:16 (2003), 14087–14091.
-
(2003)
J Biol Chem
, vol.278
, Issue.16
, pp. 14087-14091
-
-
Kovalenko, D.1
Yang, X.2
Nadeau, R.J.3
Harkins, L.K.4
Friesel, R.5
-
26
-
-
0035833471
-
Spred is a sprouty-related suppressor of ras signalling
-
26 Wakioka, T., Sasaki, A., Kato, R., et al. Spred is a sprouty-related suppressor of ras signalling. Nature 412:6847 (2001), 647–651.
-
(2001)
Nature
, vol.412
, Issue.6847
, pp. 647-651
-
-
Wakioka, T.1
Sasaki, A.2
Kato, R.3
-
27
-
-
0042858232
-
A novel interleukin-17 receptor-like protein identified in human umbilical vein endothelial cells antagonizes basic fibroblast growth factor-induced signaling
-
27 Yang, R.B., Ng, C.K., Wasserman, S.M., Komuves, L.G., Gerritsen, M.E., Topper, J.N., A novel interleukin-17 receptor-like protein identified in human umbilical vein endothelial cells antagonizes basic fibroblast growth factor-induced signaling. J Biol Chem 278:35 (2003), 33232–33238.
-
(2003)
J Biol Chem
, vol.278
, Issue.35
, pp. 33232-33238
-
-
Yang, R.B.1
Ng, C.K.2
Wasserman, S.M.3
Komuves, L.G.4
Gerritsen, M.E.5
Topper, J.N.6
-
28
-
-
11244283209
-
The role of fibroblast growth factors and their receptors in prostate cancer
-
28 Kwabi-Addo, B., Ozen, M., Ittmann, M., The role of fibroblast growth factors and their receptors in prostate cancer. Endocr Relat Cancer 11:4 (2004), 709–724.
-
(2004)
Endocr Relat Cancer
, vol.11
, Issue.4
, pp. 709-724
-
-
Kwabi-Addo, B.1
Ozen, M.2
Ittmann, M.3
-
29
-
-
0026608650
-
Correlation of basic fibroblast growth factor expression levels with the degree of malignancy and vascularity in human gliomas
-
29 Takahashi, J.A., Fukumoto, M., Igarashi, K., Oda, Y., Kikuchi, H., Hatanaka, M., Correlation of basic fibroblast growth factor expression levels with the degree of malignancy and vascularity in human gliomas. J Neurosurg 76:5 (1992), 792–798.
-
(1992)
J Neurosurg
, vol.76
, Issue.5
, pp. 792-798
-
-
Takahashi, J.A.1
Fukumoto, M.2
Igarashi, K.3
Oda, Y.4
Kikuchi, H.5
Hatanaka, M.6
-
30
-
-
80053493427
-
Beyond VEGF: inhibition of the fibroblast growth factor pathway and antiangiogenesis
-
30 Lieu, C., Heymach, J., Overman, M., Tran, H., Kopetz, S., Beyond VEGF: inhibition of the fibroblast growth factor pathway and antiangiogenesis. Clin Cancer Res 17:19 (2011), 6130–6139.
-
(2011)
Clin Cancer Res
, vol.17
, Issue.19
, pp. 6130-6139
-
-
Lieu, C.1
Heymach, J.2
Overman, M.3
Tran, H.4
Kopetz, S.5
-
31
-
-
0027053487
-
Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro
-
31 Pepper, M.S., Ferrara, N., Orci, L., Montesano, R., Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro. Biochem Biophys Res Commun 189:2 (1992), 824–831.
-
(1992)
Biochem Biophys Res Commun
, vol.189
, Issue.2
, pp. 824-831
-
-
Pepper, M.S.1
Ferrara, N.2
Orci, L.3
Montesano, R.4
-
32
-
-
77950278598
-
FGFR1 amplification drives endocrine therapy resistance and is a therapeutic target in breast cancer
-
32 Turner, N., Pearson, A., Sharpe, R., et al. FGFR1 amplification drives endocrine therapy resistance and is a therapeutic target in breast cancer. Cancer Res 70:5 (2010), 2085–2094.
-
(2010)
Cancer Res
, vol.70
, Issue.5
, pp. 2085-2094
-
-
Turner, N.1
Pearson, A.2
Sharpe, R.3
-
33
-
-
0030855812
-
Antisense targeting of basic fibroblast growth factor and fibroblast growth factor receptor-1 in human melanomas blocks intratumoral angiogenesis and tumor growth
-
33 Wang, Y., Becker, D., Antisense targeting of basic fibroblast growth factor and fibroblast growth factor receptor-1 in human melanomas blocks intratumoral angiogenesis and tumor growth. Nat Med 3:8 (1997), 887–893.
-
(1997)
Nat Med
, vol.3
, Issue.8
, pp. 887-893
-
-
Wang, Y.1
Becker, D.2
-
34
-
-
34250200790
-
Whole genome oligonucleotide-based array comparative genomic hybridization analysis identified fibroblast growth factor 1 as a prognostic marker for advanced-stage serous ovarian adenocarcinomas
-
34 Birrer, M.J., Johnson, M.E., Hao, K., et al. Whole genome oligonucleotide-based array comparative genomic hybridization analysis identified fibroblast growth factor 1 as a prognostic marker for advanced-stage serous ovarian adenocarcinomas. J Clin Oncol 25:16 (2007), 2281–2287.
-
(2007)
J Clin Oncol
, vol.25
, Issue.16
, pp. 2281-2287
-
-
Birrer, M.J.1
Johnson, M.E.2
Hao, K.3
-
35
-
-
0037906432
-
Distinct role of fibroblast growth factor-2 and vascular endothelial growth factor on tumor growth and angiogenesis
-
35 Giavazzi, R., Sennino, B., Coltrini, D., et al. Distinct role of fibroblast growth factor-2 and vascular endothelial growth factor on tumor growth and angiogenesis. Am J Pathol 162:6 (2003), 1913–1926.
-
(2003)
Am J Pathol
, vol.162
, Issue.6
, pp. 1913-1926
-
-
Giavazzi, R.1
Sennino, B.2
Coltrini, D.3
-
36
-
-
26644471951
-
Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors
-
36 Casanovas, O., Hicklin, D.J., Bergers, G., Hanahan, D., Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors. Cancer Cell 8:4 (2005), 299–309.
-
(2005)
Cancer Cell
, vol.8
, Issue.4
, pp. 299-309
-
-
Casanovas, O.1
Hicklin, D.J.2
Bergers, G.3
Hanahan, D.4
-
37
-
-
18844471324
-
Vascular endothelial growth factors VEGF-B and VEGF-C are expressed in human tumors
-
37 Salven, P., Lymboussaki, A., Heikkila, P., et al. Vascular endothelial growth factors VEGF-B and VEGF-C are expressed in human tumors. Am J Pathol 153:1 (1998), 103–108.
-
(1998)
Am J Pathol
, vol.153
, Issue.1
, pp. 103-108
-
-
Salven, P.1
Lymboussaki, A.2
Heikkila, P.3
-
38
-
-
84938095333
-
Vascular endothelial growth factor (VEGF) inhibition—a critical review
-
38 Moreira, I.S., Fernandes, P.A., Ramos, M.J., Vascular endothelial growth factor (VEGF) inhibition—a critical review. Anticancer Agents Med Chem 7:2 (2007), 223–245.
-
(2007)
Anticancer Agents Med Chem
, vol.7
, Issue.2
, pp. 223-245
-
-
Moreira, I.S.1
Fernandes, P.A.2
Ramos, M.J.3
-
39
-
-
37549006796
-
Clinical and biological significance of vascular endothelial growth factor in endometrial cancer
-
39 Kamat, A.A., Merritt, W.M., Coffey, D., et al. Clinical and biological significance of vascular endothelial growth factor in endometrial cancer. Clin Cancer Res 13:24 (2007), 7487–7495.
-
(2007)
Clin Cancer Res
, vol.13
, Issue.24
, pp. 7487-7495
-
-
Kamat, A.A.1
Merritt, W.M.2
Coffey, D.3
-
40
-
-
84888328750
-
VEGF targets the tumour cell
-
40 Goel, H.L., Mercurio, A.M., VEGF targets the tumour cell. Nat Rev Cancer 13:12 (2013), 871–882.
-
(2013)
Nat Rev Cancer
, vol.13
, Issue.12
, pp. 871-882
-
-
Goel, H.L.1
Mercurio, A.M.2
-
41
-
-
84883436058
-
Antiangiogenic agents in advanced, persistent or recurrent endometrial cancer: a novel treatment option
-
41 Gadducci, A., Sergiampietri, C., Guiggi, I., Antiangiogenic agents in advanced, persistent or recurrent endometrial cancer: a novel treatment option. Gynecol Endocrinol 29:9 (2013), 811–816.
-
(2013)
Gynecol Endocrinol
, vol.29
, Issue.9
, pp. 811-816
-
-
Gadducci, A.1
Sergiampietri, C.2
Guiggi, I.3
-
42
-
-
84924359576
-
Improvements in progression-free and overall survival due to the use of anti-angiogenic agents in gynecologic cancers
-
42 Schmid, B.C., Oehler, M.K., Improvements in progression-free and overall survival due to the use of anti-angiogenic agents in gynecologic cancers. Curr Treat Options Oncol, 16(1), 2015, 318, 10.1007/s11864-014-0318-0.
-
(2015)
Curr Treat Options Oncol
, vol.16
, Issue.1
, pp. 318
-
-
Schmid, B.C.1
Oehler, M.K.2
-
43
-
-
69249216604
-
The role of fibroblast growth factors in tumor growth
-
43 Korc, M., Friesel, R.E., The role of fibroblast growth factors in tumor growth. Curr Cancer Drug Targets 9:5 (2009), 639–651.
-
(2009)
Curr Cancer Drug Targets
, vol.9
, Issue.5
, pp. 639-651
-
-
Korc, M.1
Friesel, R.E.2
-
44
-
-
84857549430
-
FGFR2 point mutations in 466 endometrioid endometrial tumors: relationship with MSI, KRAS, PIK3CA, CTNNB1 mutations and clinicopathological features
-
44 Byron, S.A., Gartside, M., Powell, M.A., et al. FGFR2 point mutations in 466 endometrioid endometrial tumors: relationship with MSI, KRAS, PIK3CA, CTNNB1 mutations and clinicopathological features. PLoS One, 7(2), 2012, e30801.
-
(2012)
PLoS One
, vol.7
, Issue.2
, pp. e30801
-
-
Byron, S.A.1
Gartside, M.2
Powell, M.A.3
-
45
-
-
84930179410
-
Refining prognosis and identifying targetable pathways for high-risk endometrial cancer: a TransPORTEC initiative
-
45 Stelloo, E., Bosse, T., Nout, R.A., et al. Refining prognosis and identifying targetable pathways for high-risk endometrial cancer: a TransPORTEC initiative. Mod Pathol 28:6 (2015), 836–844.
-
(2015)
Mod Pathol
, vol.28
, Issue.6
, pp. 836-844
-
-
Stelloo, E.1
Bosse, T.2
Nout, R.A.3
-
46
-
-
84871656055
-
High-throughput mutation profiling of primary and metastatic endometrial cancers identifies KRAS, FGFR2 and PIK3CA to be frequently mutated
-
46 Krakstad, C., Birkeland, E., Seidel, D., et al. High-throughput mutation profiling of primary and metastatic endometrial cancers identifies KRAS, FGFR2 and PIK3CA to be frequently mutated. PLoS One, 7(12), 2012, e52795.
-
(2012)
PLoS One
, vol.7
, Issue.12
, pp. e52795
-
-
Krakstad, C.1
Birkeland, E.2
Seidel, D.3
-
47
-
-
80455164694
-
FGFR2 alterations in endometrial carcinoma
-
47 Gatius, S., Velasco, A., Azueta, A., et al. FGFR2 alterations in endometrial carcinoma. Mod Pathol 24:11 (2011), 1500–1510.
-
(2011)
Mod Pathol
, vol.24
, Issue.11
, pp. 1500-1510
-
-
Gatius, S.1
Velasco, A.2
Azueta, A.3
-
48
-
-
84899878210
-
Designing a high-throughput somatic mutation profiling panel specifically for gynaecological cancers
-
48 Spaans, V.M., Trietsch, M.D., Crobach, S., et al. Designing a high-throughput somatic mutation profiling panel specifically for gynaecological cancers. PLoS One, 9(3), 2014, e93451.
-
(2014)
PLoS One
, vol.9
, Issue.3
, pp. e93451
-
-
Spaans, V.M.1
Trietsch, M.D.2
Crobach, S.3
-
49
-
-
0035912715
-
Structural basis for fibroblast growth factor receptor 2 activation in apert syndrome
-
49 Ibrahimi, O.A., Eliseenkova, A.V., Plotnikov, A.N., Yu, K., Ornitz, D.M., Mohammadi, M., Structural basis for fibroblast growth factor receptor 2 activation in apert syndrome. Proc Natl Acad Sci U S A 98:13 (2001), 7182–7187.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, Issue.13
, pp. 7182-7187
-
-
Ibrahimi, O.A.1
Eliseenkova, A.V.2
Plotnikov, A.N.3
Yu, K.4
Ornitz, D.M.5
Mohammadi, M.6
-
50
-
-
5444250989
-
Biochemical analysis of pathogenic ligand-dependent FGFR2 mutations suggests distinct pathophysiological mechanisms for craniofacial and limb abnormalities
-
50 Ibrahimi, O.A., Zhang, F., Eliseenkova, A.V., Itoh, N., Linhardt, R.J., Mohammadi, M., Biochemical analysis of pathogenic ligand-dependent FGFR2 mutations suggests distinct pathophysiological mechanisms for craniofacial and limb abnormalities. Hum Mol Genet 13:19 (2004), 2313–2324.
-
(2004)
Hum Mol Genet
, vol.13
, Issue.19
, pp. 2313-2324
-
-
Ibrahimi, O.A.1
Zhang, F.2
Eliseenkova, A.V.3
Itoh, N.4
Linhardt, R.J.5
Mohammadi, M.6
-
51
-
-
0034687699
-
Loss of fibroblast growth factor receptor 2 ligand-binding specificity in apert syndrome
-
51 Yu, K., Herr, A.B., Waksman, G., Ornitz, D.M., Loss of fibroblast growth factor receptor 2 ligand-binding specificity in apert syndrome. Proc Natl Acad Sci U S A 97:26 (2000), 14536–14541.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, Issue.26
, pp. 14536-14541
-
-
Yu, K.1
Herr, A.B.2
Waksman, G.3
Ornitz, D.M.4
-
52
-
-
84899545178
-
Altered expression of fibroblast growth factor receptor 2 isoform IIIc: Relevance to endometrioid adenocarcinoma carcinogenesis and histological differentiation
-
52 Peng, W.X., Kudo, M., Fujii, T., Teduka, K., Naito, Z., Altered expression of fibroblast growth factor receptor 2 isoform IIIc: Relevance to endometrioid adenocarcinoma carcinogenesis and histological differentiation. Int J Clin Exp Pathol 7:3 (2014), 1069–1076.
-
(2014)
Int J Clin Exp Pathol
, vol.7
, Issue.3
, pp. 1069-1076
-
-
Peng, W.X.1
Kudo, M.2
Fujii, T.3
Teduka, K.4
Naito, Z.5
-
53
-
-
84877679916
-
Activity of the fibroblast growth factor receptor inhibitors dovitinib (TKI258) and NVP-BGJ398 in human endometrial cancer cells
-
53 Konecny, G.E., Kolarova, T., O'Brien, N.A., et al. Activity of the fibroblast growth factor receptor inhibitors dovitinib (TKI258) and NVP-BGJ398 in human endometrial cancer cells. Mol Cancer Ther 12:5 (2013), 632–642.
-
(2013)
Mol Cancer Ther
, vol.12
, Issue.5
, pp. 632-642
-
-
Konecny, G.E.1
Kolarova, T.2
O'Brien, N.A.3
-
54
-
-
84881039897
-
The N550K/H mutations in FGFR2 confer differential resistance to PD173074, dovitinib, and ponatinib ATP-competitive inhibitors
-
54 Byron, S.A., Chen, H., Wortmann, A., et al. The N550K/H mutations in FGFR2 confer differential resistance to PD173074, dovitinib, and ponatinib ATP-competitive inhibitors. Neoplasia 15:8 (2013), 975–988.
-
(2013)
Neoplasia
, vol.15
, Issue.8
, pp. 975-988
-
-
Byron, S.A.1
Chen, H.2
Wortmann, A.3
-
55
-
-
0029493586
-
Expression of basic fibroblast growth factor and its mRNA in uterine endometrial cancers
-
55 Fujimoto, J., Hori, M., Ichigo, S., Tamaya, T., Expression of basic fibroblast growth factor and its mRNA in uterine endometrial cancers. Invasion Metastasis 15:5–6 (1995), 203–210.
-
(1995)
Invasion Metastasis
, vol.15
, Issue.5-6
, pp. 203-210
-
-
Fujimoto, J.1
Hori, M.2
Ichigo, S.3
Tamaya, T.4
-
56
-
-
37049027678
-
FGF2 transcript levels are positively correlated with EGF and IGF-1 in the malignant endometrium
-
56 Soufla, G., Sifakis, S., Spandidos, D.A., FGF2 transcript levels are positively correlated with EGF and IGF-1 in the malignant endometrium. Cancer Lett 259:2 (2008), 146–155.
-
(2008)
Cancer Lett
, vol.259
, Issue.2
, pp. 146-155
-
-
Soufla, G.1
Sifakis, S.2
Spandidos, D.A.3
-
57
-
-
77349109017
-
Expression of efp, VEGF and bFGF in normal, hyperplastic and malignant endometrial tissue
-
57 Dai, H., Zhao, S., Xu, L., Chen, A., Dai, S., Expression of efp, VEGF and bFGF in normal, hyperplastic and malignant endometrial tissue. Oncol Rep 23:3 (2010), 795–799.
-
(2010)
Oncol Rep
, vol.23
, Issue.3
, pp. 795-799
-
-
Dai, H.1
Zhao, S.2
Xu, L.3
Chen, A.4
Dai, S.5
-
58
-
-
0029891642
-
Expressions of the fibroblast growth factor family (FGF-1, -2 and -4) mRNA in endometrial cancers
-
58 Fujimoto, J., Hori, M., Ichigo, S., Tamaya, T., Expressions of the fibroblast growth factor family (FGF-1, -2 and -4) mRNA in endometrial cancers. Tumour Biol 17:4 (1996), 226–233.
-
(1996)
Tumour Biol
, vol.17
, Issue.4
, pp. 226-233
-
-
Fujimoto, J.1
Hori, M.2
Ichigo, S.3
Tamaya, T.4
-
59
-
-
84876103735
-
Blockade of nonhormonal fibroblast growth factors by FP-1039 inhibits growth of multiple types of cancer
-
59 Harding, T.C., Long, L., Palencia, S., et al. Blockade of nonhormonal fibroblast growth factors by FP-1039 inhibits growth of multiple types of cancer. Sci Transl Med, 5(178), 2013, 178ra39.
-
(2013)
Sci Transl Med
, vol.5
, Issue.178
, pp. 178ra39
-
-
Harding, T.C.1
Long, L.2
Palencia, S.3
-
60
-
-
84880165043
-
Preclinical efficacy of FP-1039 (FGFR1:Fc) in endometrial carcinoma modelswith activating mutations in FGFR2
-
AACR Annual Meeting; Abstract 2597.
-
60 Harding TC, Palencia S, Long L, et al. Preclinical efficacy of FP-1039 (FGFR1:Fc) in endometrial carcinoma modelswith activating mutations in FGFR2. AACR Annual Meeting; 2010. Abstract 2597.
-
(2010)
-
-
Harding, T.C.1
Palencia, S.2
Long, L.3
-
61
-
-
46249129455
-
Extracellular point mutations in FGFR2 elicit unexpected changes in intracellular signalling
-
61 Ahmed, Z., Schuller, A.C., Suhling, K., Tregidgo, C., Ladbury, J.E., Extracellular point mutations in FGFR2 elicit unexpected changes in intracellular signalling. Biochem J 413:1 (2008), 37–49.
-
(2008)
Biochem J
, vol.413
, Issue.1
, pp. 37-49
-
-
Ahmed, Z.1
Schuller, A.C.2
Suhling, K.3
Tregidgo, C.4
Ladbury, J.E.5
-
62
-
-
0037108225
-
FGFs, their receptors, and human limb malformations: clinical and molecular correlations
-
62 Wilkie, A.O., Patey, S.J., Kan, S.H., van den Ouweland, A.M., Hamel, B.C., FGFs, their receptors, and human limb malformations: clinical and molecular correlations. Am J Med Genet 112:3 (2002), 266–278.
-
(2002)
Am J Med Genet
, vol.112
, Issue.3
, pp. 266-278
-
-
Wilkie, A.O.1
Patey, S.J.2
Kan, S.H.3
van den Ouweland, A.M.4
Hamel, B.C.5
-
63
-
-
84877928037
-
Combined targeting of FGFR2 and mTOR by ponatinib and ridaforolimus results in synergistic antitumor activity in FGFR2 mutant endometrial cancer models
-
63 Gozgit, J.M., Squillace, R.M., Wongchenko, M.J., et al. Combined targeting of FGFR2 and mTOR by ponatinib and ridaforolimus results in synergistic antitumor activity in FGFR2 mutant endometrial cancer models. Cancer Chemother Pharmacol 71:5 (2013), 1315–1323.
-
(2013)
Cancer Chemother Pharmacol
, vol.71
, Issue.5
, pp. 1315-1323
-
-
Gozgit, J.M.1
Squillace, R.M.2
Wongchenko, M.J.3
-
64
-
-
84908030997
-
A phase II trial of brivanib in recurrent or persistent endometrial cancer: an NRG oncology/gynecologic oncology group study
-
64 Powell, M.A., Sill, M.W., Goodfellow, P.J., et al. A phase II trial of brivanib in recurrent or persistent endometrial cancer: an NRG oncology/gynecologic oncology group study. Gynecol Oncol 135:1 (2014), 38–43.
-
(2014)
Gynecol Oncol
, vol.135
, Issue.1
, pp. 38-43
-
-
Powell, M.A.1
Sill, M.W.2
Goodfellow, P.J.3
-
65
-
-
84920741562
-
A phase II evaluation of nintedanib (BIBF-1120) in the treatment of recurrent or persistent endometrial cancer: an NRG oncology/gynecologic oncology group study
-
65 Dizon, D.S., Sill, M.W., Schilder, J.M., et al. A phase II evaluation of nintedanib (BIBF-1120) in the treatment of recurrent or persistent endometrial cancer: an NRG oncology/gynecologic oncology group study. Gynecol Oncol 135:3 (2014), 441–445.
-
(2014)
Gynecol Oncol
, vol.135
, Issue.3
, pp. 441-445
-
-
Dizon, D.S.1
Sill, M.W.2
Schilder, J.M.3
-
66
-
-
85016338961
-
Phase 2 study of second-line dovitinib (TKI258) in patients with fibroblast growth factor receptor 2 (FGFR2)-mutated or -nonmutated advanced and/or metastatic endometrial cancer
-
[Abstract LBA27]
-
66 Konecny, G.E., Finkler, N., Garcia, A.A., et al. Phase 2 study of second-line dovitinib (TKI258) in patients with fibroblast growth factor receptor 2 (FGFR2)-mutated or -nonmutated advanced and/or metastatic endometrial cancer. Eur Soc Med Oncol, 2014 [Abstract LBA27].
-
(2014)
Eur Soc Med Oncol
-
-
Konecny, G.E.1
Finkler, N.2
Garcia, A.A.3
-
67
-
-
84930255300
-
Second-line dovitinib (TKI258) in patients with FGFR2-mutated or FGFR2-non-mutated advanced or metastatic endometrial cancer: A non-randomised, open-label, two-group, two-stage, phase 2 study
-
67 Konecny, G.E., Finkler, N., Garcia, A.A., et al. Second-line dovitinib (TKI258) in patients with FGFR2-mutated or FGFR2-non-mutated advanced or metastatic endometrial cancer: A non-randomised, open-label, two-group, two-stage, phase 2 study. Lancet Oncol 16:6 (2015), 686–694.
-
(2015)
Lancet Oncol
, vol.16
, Issue.6
, pp. 686-694
-
-
Konecny, G.E.1
Finkler, N.2
Garcia, A.A.3
-
68
-
-
84947233902
-
Phase I dose-escalation study of the multikinase inhibitor lenvatinib in patients with advanced solid tumors and in an expanded cohort of patients with melanoma
-
68 Hong, D.S., Kurzrock, R., Wheler, J.J., et al. Phase I dose-escalation study of the multikinase inhibitor lenvatinib in patients with advanced solid tumors and in an expanded cohort of patients with melanoma. Clin Cancer Res 21:21 (2015), 4801–4810.
-
(2015)
Clin Cancer Res
, vol.21
, Issue.21
, pp. 4801-4810
-
-
Hong, D.S.1
Kurzrock, R.2
Wheler, J.J.3
-
69
-
-
84892811166
-
A phase II trial of lenvatinib in patients with advanced or recurrent endometrial cancer: angiopoietin-2 as a predictive marker for clinical outcomes
-
[ASCO Annual Meeting Abstracts, Abstract 5520]
-
69 Vergote, I., Teneriello, M., Powell, M.A., et al. A phase II trial of lenvatinib in patients with advanced or recurrent endometrial cancer: angiopoietin-2 as a predictive marker for clinical outcomes. J Clin Oncol, 31(suppl), 2013 [ASCO Annual Meeting Abstracts, Abstract 5520].
-
(2013)
J Clin Oncol
, vol.31
-
-
Vergote, I.1
Teneriello, M.2
Powell, M.A.3
-
70
-
-
84896700734
-
Analysis of plasma biomarker and tumor genetic alterations from a phase II trial of lenvatinib in patients with advanced endometrial cancer
-
[ASCO Annual Meeting Abstracts, Abstract 5591]
-
70 Funahashi, Y., Penson, R.T., Powell, M.A., et al. Analysis of plasma biomarker and tumor genetic alterations from a phase II trial of lenvatinib in patients with advanced endometrial cancer. J Clin Oncol, 31(suppl), 2013 [ASCO Annual Meeting Abstracts, Abstract 5591].
-
(2013)
J Clin Oncol
, vol.31
-
-
Funahashi, Y.1
Penson, R.T.2
Powell, M.A.3
-
71
-
-
84859402751
-
Ponatinib (AP24534), a multitargeted pan-FGFR inhibitor with activity in multiple FGFR-amplified or mutated cancer models
-
71 Gozgit, J.M., Wong, M.J., Moran, L., et al. Ponatinib (AP24534), a multitargeted pan-FGFR inhibitor with activity in multiple FGFR-amplified or mutated cancer models. Mol Cancer Ther 11:3 (2012), 690–699.
-
(2012)
Mol Cancer Ther
, vol.11
, Issue.3
, pp. 690-699
-
-
Gozgit, J.M.1
Wong, M.J.2
Moran, L.3
-
72
-
-
84905568519
-
A phase II trial of sunitinib in women with metastatic or recurrent endometrial carcinoma: a study of the princess margaret, chicago and california consortia
-
72 Castonguay, V., Lheureux, S., Welch, S., et al. A phase II trial of sunitinib in women with metastatic or recurrent endometrial carcinoma: a study of the princess margaret, chicago and california consortia. Gynecol Oncol 134:2 (2014), 274–280.
-
(2014)
Gynecol Oncol
, vol.134
, Issue.2
, pp. 274-280
-
-
Castonguay, V.1
Lheureux, S.2
Welch, S.3
-
73
-
-
77949337347
-
A phase II study of sorafenib in advanced uterine carcinoma/carcinosarcoma: a trial of the chicago, PMH, and california phase II consortia
-
73 Nimeiri, H.S., Oza, A.M., Morgan, R.J., et al. A phase II study of sorafenib in advanced uterine carcinoma/carcinosarcoma: a trial of the chicago, PMH, and california phase II consortia. Gynecol Oncol 117:1 (2010), 37–40.
-
(2010)
Gynecol Oncol
, vol.117
, Issue.1
, pp. 37-40
-
-
Nimeiri, H.S.1
Oza, A.M.2
Morgan, R.J.3
-
74
-
-
34247128217
-
A phase II trial of thalidomide in patients with refractory endometrial cancer and correlation with angiogenesis biomarkers: a gynecologic oncology group study
-
74 McMeekin, D.S., Sill, M.W., Benbrook, D., et al. A phase II trial of thalidomide in patients with refractory endometrial cancer and correlation with angiogenesis biomarkers: a gynecologic oncology group study. Gynecol Oncol 105:2 (2007), 508–516.
-
(2007)
Gynecol Oncol
, vol.105
, Issue.2
, pp. 508-516
-
-
McMeekin, D.S.1
Sill, M.W.2
Benbrook, D.3
-
75
-
-
84867404688
-
A phase II trial of thalidomide in patients with refractory uterine carcinosarcoma and correlation with biomarkers of angiogenesis: a gynecologic oncology group study
-
75 McMeekin, D.S., Sill, M.W., Darcy, K.M., et al. A phase II trial of thalidomide in patients with refractory uterine carcinosarcoma and correlation with biomarkers of angiogenesis: a gynecologic oncology group study. Gynecol Oncol 127:2 (2012), 356–361.
-
(2012)
Gynecol Oncol
, vol.127
, Issue.2
, pp. 356-361
-
-
McMeekin, D.S.1
Sill, M.W.2
Darcy, K.M.3
-
76
-
-
79957949444
-
Phase II trial of bevacizumab in recurrent or persistent endometrial cancer: a gynecologic oncology group study
-
76 Aghajanian, C., Sill, M.W., Darcy, K.M., et al. Phase II trial of bevacizumab in recurrent or persistent endometrial cancer: a gynecologic oncology group study. J Clin Oncol 29:16 (2011), 2259–2265.
-
(2011)
J Clin Oncol
, vol.29
, Issue.16
, pp. 2259-2265
-
-
Aghajanian, C.1
Sill, M.W.2
Darcy, K.M.3
-
77
-
-
84875539239
-
Phase II trial of combination bevacizumab and temsirolimus in the treatment of recurrent or persistent endometrial carcinoma: a gynecologic oncology group study
-
77 Alvarez, E.A., Brady, W.E., Walker, J.L., et al. Phase II trial of combination bevacizumab and temsirolimus in the treatment of recurrent or persistent endometrial carcinoma: a gynecologic oncology group study. Gynecol Oncol 129:1 (2013), 22–27.
-
(2013)
Gynecol Oncol
, vol.129
, Issue.1
, pp. 22-27
-
-
Alvarez, E.A.1
Brady, W.E.2
Walker, J.L.3
-
78
-
-
84868588283
-
A phase II evaluation of aflibercept in the treatment of recurrent or persistent endometrial cancer: a gynecologic oncology group study
-
78 Coleman, R.L., Sill, M.W., Lankes, H.A., et al. A phase II evaluation of aflibercept in the treatment of recurrent or persistent endometrial cancer: a gynecologic oncology group study. Gynecol Oncol 127:3 (2012), 538–543.
-
(2012)
Gynecol Oncol
, vol.127
, Issue.3
, pp. 538-543
-
-
Coleman, R.L.1
Sill, M.W.2
Lankes, H.A.3
-
79
-
-
0028798546
-
Apert syndrome results from localized mutations of FGFR2 and is allelic with crouzon syndrome
-
79 Wilkie, A.O., Slaney, S.F., Oldridge, M., et al. Apert syndrome results from localized mutations of FGFR2 and is allelic with crouzon syndrome. Nat Genet 9:2 (1995), 165–172.
-
(1995)
Nat Genet
, vol.9
, Issue.2
, pp. 165-172
-
-
Wilkie, A.O.1
Slaney, S.F.2
Oldridge, M.3
-
80
-
-
0030941036
-
Activation of FGF receptors by mutations in the transmembrane domain
-
80 Li, Y., Mangasarian, K., Mansukhani, A., Basilico, C., Activation of FGF receptors by mutations in the transmembrane domain. Oncogene 14:12 (1997), 1397–1406.
-
(1997)
Oncogene
, vol.14
, Issue.12
, pp. 1397-1406
-
-
Li, Y.1
Mangasarian, K.2
Mansukhani, A.3
Basilico, C.4
-
81
-
-
0030812901
-
Ligand-independent activation of fibroblast growth factor receptor-2 by carboxyl terminal alterations
-
81 Lorenzi, M.V., Castagnino, P., Chen, Q., Chedid, M., Miki, T., Ligand-independent activation of fibroblast growth factor receptor-2 by carboxyl terminal alterations. Oncogene 15:7 (1997), 817–826.
-
(1997)
Oncogene
, vol.15
, Issue.7
, pp. 817-826
-
-
Lorenzi, M.V.1
Castagnino, P.2
Chen, Q.3
Chedid, M.4
Miki, T.5
|