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Volumn 1047, Issue , 2017, Pages 97-105

Exhaled breath condensate analysis from intubated newborns by nano-HPLC coupled to high resolution MS

Author keywords

Exhaled breath condensate (EBC); HPLC; Mass spectrometry; Metabolomics; Newborns; Pneumonia; Proteomic; Respiratory diseases

Indexed keywords

MASS SPECTROMETRY; METABOLITES; NONINVASIVE MEDICAL PROCEDURES; PROTEINS; PULMONARY DISEASES;

EID: 85009266755     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2016.12.036     Document Type: Article
Times cited : (27)

References (66)
  • 2
    • 0035041662 scopus 로고    scopus 로고
    • Prevention of bronchopulmonary dysplasia
    • [2] Jobe, A.H., Ikegami, M., Prevention of bronchopulmonary dysplasia. Curr. Opin. Pediatr. 13 (2001), 124–129.
    • (2001) Curr. Opin. Pediatr. , vol.13 , pp. 124-129
    • Jobe, A.H.1    Ikegami, M.2
  • 3
    • 0036189815 scopus 로고    scopus 로고
    • Developmental Epidemiology Network, Chorioamnionitis, mechanical ventilation, and postnatal sepsis as modulators of chronic lung disease in preterm infants
    • [3] Van Marter, L.J., Dammann, O., Allred, E.N., Leviton, A., Pagano, M., Moore, M., Martin, C., Developmental Epidemiology Network, Chorioamnionitis, mechanical ventilation, and postnatal sepsis as modulators of chronic lung disease in preterm infants. J. Pediatr. 140 (2002), 171–176.
    • (2002) J. Pediatr. , vol.140 , pp. 171-176
    • Van Marter, L.J.1    Dammann, O.2    Allred, E.N.3    Leviton, A.4    Pagano, M.5    Moore, M.6    Martin, C.7
  • 4
    • 1542779741 scopus 로고    scopus 로고
    • Role of cytokines in hyperoxia mediated inflammation in the developing lung
    • [4] Bustani, P., Kotecha, S., Role of cytokines in hyperoxia mediated inflammation in the developing lung. ABBV Front Biosci 8 (2003), s694–704.
    • (2003) ABBV Front Biosci , vol.8 , pp. s694-704
    • Bustani, P.1    Kotecha, S.2
  • 5
    • 79953886949 scopus 로고    scopus 로고
    • The new bronchopulmonary dysplasia
    • [5] Jobe, A.H., The new bronchopulmonary dysplasia. Curr. Opin. Pediatr. 23 (2011), 167–172.
    • (2011) Curr. Opin. Pediatr. , vol.23 , pp. 167-172
    • Jobe, A.H.1
  • 6
    • 83555177348 scopus 로고    scopus 로고
    • Perinatal inflammation and lung injury
    • [6] Viscardi, R.M., Perinatal inflammation and lung injury. Sem. Fetal Neonatal Med. 17 (2012), 30–35.
    • (2012) Sem. Fetal Neonatal Med. , vol.17 , pp. 30-35
    • Viscardi, R.M.1
  • 7
    • 78650833245 scopus 로고    scopus 로고
    • Biomarkers of neutrophil-mediated glutathione and protein oxidation in tracheal aspirates from preterm infants: association with bacterial infection
    • [7] Harwood, D.T., Darlow, B.A., Cheah, F.C., McNeill, N., Graham, P., Winterbourn, C.C., Biomarkers of neutrophil-mediated glutathione and protein oxidation in tracheal aspirates from preterm infants: association with bacterial infection. Pediatr. Res. 69 (2011), 28–33.
    • (2011) Pediatr. Res. , vol.69 , pp. 28-33
    • Harwood, D.T.1    Darlow, B.A.2    Cheah, F.C.3    McNeill, N.4    Graham, P.5    Winterbourn, C.C.6
  • 8
    • 84877580980 scopus 로고    scopus 로고
    • Inflammatory mediator patterns in tracheal aspirate and their association with bronchopulmonary dysplasia in very low birth weight neonates
    • [8] Schneibel, K.R., Fitzpatrick, A.M., Ping, X.D., Brown, L.A., Gauthier, T.W., Inflammatory mediator patterns in tracheal aspirate and their association with bronchopulmonary dysplasia in very low birth weight neonates. J. Perinatol. 33 (2013), 383–387.
    • (2013) J. Perinatol. , vol.33 , pp. 383-387
    • Schneibel, K.R.1    Fitzpatrick, A.M.2    Ping, X.D.3    Brown, L.A.4    Gauthier, T.W.5
  • 9
    • 84884995584 scopus 로고    scopus 로고
    • Pilot study using proteomics to identify predictive biomarkers of necrotizing enterocolitis from buccal swabs in very low birth weight infants
    • [9] Torrazza, R.M., Li, N., Young, C., Kobeissy, F., Chow, M., Chen, S.X., Mai, V., Sharma, R., Hudak, M., Shuster, J., Neu, J., Pilot study using proteomics to identify predictive biomarkers of necrotizing enterocolitis from buccal swabs in very low birth weight infants. Neonatology 104 (2013), 234–242.
    • (2013) Neonatology , vol.104 , pp. 234-242
    • Torrazza, R.M.1    Li, N.2    Young, C.3    Kobeissy, F.4    Chow, M.5    Chen, S.X.6    Mai, V.7    Sharma, R.8    Hudak, M.9    Shuster, J.10    Neu, J.11
  • 12
    • 48949087676 scopus 로고    scopus 로고
    • Identification of urinary biomarkers by proteomics in newborns: use in obstructive nephropathy
    • [12] Decramer, S., Zurbig, P., Wittke, S., Mischak, H., Bascands, J.L., Schanstra, J.P., Identification of urinary biomarkers by proteomics in newborns: use in obstructive nephropathy. Contrib. Nephrol. 160 (2008), 127–141.
    • (2008) Contrib. Nephrol. , vol.160 , pp. 127-141
    • Decramer, S.1    Zurbig, P.2    Wittke, S.3    Mischak, H.4    Bascands, J.L.5    Schanstra, J.P.6
  • 14
    • 84888433163 scopus 로고    scopus 로고
    • Exhaled breath condensate: determination of non-volatile compounds and their potential for clinical diagnosis and monitoring. A review
    • [14] Kuban, P., Foret, F., Exhaled breath condensate: determination of non-volatile compounds and their potential for clinical diagnosis and monitoring. A review. Anal. Chim. Acta 805 (2013), 1–18.
    • (2013) Anal. Chim. Acta , vol.805 , pp. 1-18
    • Kuban, P.1    Foret, F.2
  • 15
    • 84961185045 scopus 로고    scopus 로고
    • Letter Comparison of pyridine and pyrazine derivatives distributions in exhaled breath and exhaled breath condensate after smoking
    • [15] Chagovets, V., Kononikhin, A., Starodubtseva, N., Ding, J., Chen, H., Frankevich, V., Letter Comparison of pyridine and pyrazine derivatives distributions in exhaled breath and exhaled breath condensate after smoking. Eur. J. Mass Spectrom. 21 (2015), 829–832.
    • (2015) Eur. J. Mass Spectrom. , vol.21 , pp. 829-832
    • Chagovets, V.1    Kononikhin, A.2    Starodubtseva, N.3    Ding, J.4    Chen, H.5    Frankevich, V.6
  • 18
    • 84922358314 scopus 로고    scopus 로고
    • Trace detection of endogenous human volatile organic compounds for search, rescue and emergency applications
    • [18] Agapiou, A., Amann, A., Mochalski, P., Statheropoulos, M., Thomas, C.L.P., Trace detection of endogenous human volatile organic compounds for search, rescue and emergency applications. Trends Anal. Chem. 66 (2015), 158–175.
    • (2015) Trends Anal. Chem. , vol.66 , pp. 158-175
    • Agapiou, A.1    Amann, A.2    Mochalski, P.3    Statheropoulos, M.4    Thomas, C.L.P.5
  • 22
    • 84865715084 scopus 로고    scopus 로고
    • Evidence of unexpected oxidative stress in airways of adolescents born very pre-term
    • [22] Filippone, M., Bonetto, G., Corradi, M., Frigo, A.C., Baraldi, E., Evidence of unexpected oxidative stress in airways of adolescents born very pre-term. Eur. Respir. J. 40 (2012), 1253–1259.
    • (2012) Eur. Respir. J. , vol.40 , pp. 1253-1259
    • Filippone, M.1    Bonetto, G.2    Corradi, M.3    Frigo, A.C.4    Baraldi, E.5
  • 25
    • 14744303524 scopus 로고    scopus 로고
    • Acid-base equilibrium in exhaled breath condensate of allergic asthmatic children
    • [25] Carraro, S., Folesani, G., Corradi, M., Zanconato, S., Gaston, B., Baraldi, E., Acid-base equilibrium in exhaled breath condensate of allergic asthmatic children. Allergy 60 (2005), 476–481.
    • (2005) Allergy , vol.60 , pp. 476-481
    • Carraro, S.1    Folesani, G.2    Corradi, M.3    Zanconato, S.4    Gaston, B.5    Baraldi, E.6
  • 28
    • 84857440052 scopus 로고    scopus 로고
    • NMR spectroscopy metabolomic profiling of exhaled breath condensate in patients with stable and unstable cystic fibrosis
    • [28] Montuschi, P., Paris, D., Melck, D., Lucidi, V., Ciabattoni, G., Raia, V., Calabrese, C., Bush, A., Barnes, P.J., Motta, A., NMR spectroscopy metabolomic profiling of exhaled breath condensate in patients with stable and unstable cystic fibrosis. Thorax 67 (2012), 222–228.
    • (2012) Thorax , vol.67 , pp. 222-228
    • Montuschi, P.1    Paris, D.2    Melck, D.3    Lucidi, V.4    Ciabattoni, G.5    Raia, V.6    Calabrese, C.7    Bush, A.8    Barnes, P.J.9    Motta, A.10
  • 29
    • 84930895727 scopus 로고    scopus 로고
    • The analysis of volatile organic compounds in exhaled breath and biomarkers in exhaled breath condensate in children − clinical tools or scientific toys?
    • [29] van Mastrigt, E., de Jongste, J.C., Pijnenburg, M.W., The analysis of volatile organic compounds in exhaled breath and biomarkers in exhaled breath condensate in children − clinical tools or scientific toys?. Clin. Exp. Allergy 45 (2015), 1170–1188.
    • (2015) Clin. Exp. Allergy , vol.45 , pp. 1170-1188
    • van Mastrigt, E.1    de Jongste, J.C.2    Pijnenburg, M.W.3
  • 33
    • 84858253670 scopus 로고    scopus 로고
    • (4) and 8-isoprostane in the exhaled breath condensate of children hospitalized for status asthmaticus
    • [33] Hasan, R.A., O'Brien, E., Mancuso, P., Lipoxin, A., (4) and 8-isoprostane in the exhaled breath condensate of children hospitalized for status asthmaticus. Pediatric Crit. Care Med. 13 (2012), 141–145.
    • (2012) Pediatric Crit. Care Med. , vol.13 , pp. 141-145
    • Hasan, R.A.1    O'Brien, E.2    Mancuso, P.3    Lipoxin, A.4
  • 34
    • 84864402044 scopus 로고    scopus 로고
    • Lung function and biomarkers of airway inflammation during and after hospitalization for acute exacerbations of childhood asthma associated with viral respiratory symptoms
    • [34] Debley, J.S., Cochrane, E.S., Redding, G.J., Carter, E.R., Lung function and biomarkers of airway inflammation during and after hospitalization for acute exacerbations of childhood asthma associated with viral respiratory symptoms. Ann. Allergy Asthma Immunol. 109 (2012), 114–120.
    • (2012) Ann. Allergy Asthma Immunol. , vol.109 , pp. 114-120
    • Debley, J.S.1    Cochrane, E.S.2    Redding, G.J.3    Carter, E.R.4
  • 35
    • 84860387834 scopus 로고    scopus 로고
    • Exhaled breath condensate MMP-9 level and its relationship with asthma severity and interleukin-4/10 levels in children
    • [35] Karakoc, G.B., Yukselen, A., Yilmaz, M., Altintas, D.U., Kendirli, S.G., Exhaled breath condensate MMP-9 level and its relationship with asthma severity and interleukin-4/10 levels in children. Ann. Allergy Asthma Immunol. 108 (2012), 300–304.
    • (2012) Ann. Allergy Asthma Immunol. , vol.108 , pp. 300-304
    • Karakoc, G.B.1    Yukselen, A.2    Yilmaz, M.3    Altintas, D.U.4    Kendirli, S.G.5
  • 36
    • 2942611118 scopus 로고    scopus 로고
    • Increased macrophage-derived chemokine in exhaled breath condensate and plasma from children with asthma
    • [36] Leung, T.F., Wong, G.W., Ko, F.W., Lam, C.W., Fok, T.F., Increased macrophage-derived chemokine in exhaled breath condensate and plasma from children with asthma. Clin. Exp. Allergy 34 (2004), 786–791.
    • (2004) Clin. Exp. Allergy , vol.34 , pp. 786-791
    • Leung, T.F.1    Wong, G.W.2    Ko, F.W.3    Lam, C.W.4    Fok, T.F.5
  • 38
    • 35848952935 scopus 로고    scopus 로고
    • Chronic lung disease after premature birth
    • [38] Baraldi, E., Filippone, M., Chronic lung disease after premature birth. N. Engl. J. Med. 357 (2007), 1946–1955.
    • (2007) N. Engl. J. Med. , vol.357 , pp. 1946-1955
    • Baraldi, E.1    Filippone, M.2
  • 39
    • 33644657977 scopus 로고    scopus 로고
    • Association of hydrogen peroxide in exhaled breath condensates from infants with respiratory distress syndrome with the development of chronic lung disease
    • [39] Cheah, F.C., Darlow, B.A., Winterbourn, C.C., Association of hydrogen peroxide in exhaled breath condensates from infants with respiratory distress syndrome with the development of chronic lung disease. Arch. Dis. Child. Fetal Neonatal Ed., 91, 2006, F155.
    • (2006) Arch. Dis. Child. Fetal Neonatal Ed. , vol.91 , pp. F155
    • Cheah, F.C.1    Darlow, B.A.2    Winterbourn, C.C.3
  • 42
    • 0029360686 scopus 로고
    • Glutathione metabolism in newborns: evidence for glutathione deficiency in plasma, bronchoalveolar lavage fluid, and lymphocytes in prematures
    • [42] Jain, A., Mehta, T., Auld, P.A., Rodrigues, J., Ward, R.F., Schwartz, M.K., Martensson, J., Glutathione metabolism in newborns: evidence for glutathione deficiency in plasma, bronchoalveolar lavage fluid, and lymphocytes in prematures. Pediatr. Pulmonol. 20 (1995), 160–166.
    • (1995) Pediatr. Pulmonol. , vol.20 , pp. 160-166
    • Jain, A.1    Mehta, T.2    Auld, P.A.3    Rodrigues, J.4    Ward, R.F.5    Schwartz, M.K.6    Martensson, J.7
  • 43
    • 11144252646 scopus 로고    scopus 로고
    • Exhaled breath measures of inflammation: are they useful in neonatal chronic lung disease?, Archives of disease in childhood
    • [43] Harrison, C.M., Andersen, C.C., Exhaled breath measures of inflammation: are they useful in neonatal chronic lung disease?, Archives of disease in childhood. Fetal Neonatal Ed. 90 (2005), F6–10.
    • (2005) Fetal Neonatal Ed. , vol.90 , pp. F6-10
    • Harrison, C.M.1    Andersen, C.C.2
  • 46
    • 84938818771 scopus 로고    scopus 로고
    • Analysis of the human adult urinary metabolome variations with age, body mass index, and gender by implementing a comprehensive workflow for univariate and OPLS statistical analyses
    • [46] Thevenot, E.A., Roux, A., Xu, Y., Ezan, E., Junot, C., Analysis of the human adult urinary metabolome variations with age, body mass index, and gender by implementing a comprehensive workflow for univariate and OPLS statistical analyses. J. Proteome Res. 14 (2015), 3322–3335.
    • (2015) J. Proteome Res. , vol.14 , pp. 3322-3335
    • Thevenot, E.A.1    Roux, A.2    Xu, Y.3    Ezan, E.4    Junot, C.5
  • 47
    • 40649106269 scopus 로고    scopus 로고
    • Human skin keratins are the major proteins in exhaled breath condensate
    • [47] Hoffmann, H.J., Tabaksblat, L.M., Enghild, J.J., Dahl, R., Human skin keratins are the major proteins in exhaled breath condensate. Eur. Respir. J. 31 (2008), 380–384.
    • (2008) Eur. Respir. J. , vol.31 , pp. 380-384
    • Hoffmann, H.J.1    Tabaksblat, L.M.2    Enghild, J.J.3    Dahl, R.4
  • 49
    • 0035987508 scopus 로고    scopus 로고
    • Protein pattern of exhaled breath condensate and saliva
    • [49] Griese, M., Noss, J., von Bredow, C., Protein pattern of exhaled breath condensate and saliva. Proteomics 2 (2002), 690–696.
    • (2002) Proteomics , vol.2 , pp. 690-696
    • Griese, M.1    Noss, J.2    von Bredow, C.3
  • 51
    • 57049166456 scopus 로고    scopus 로고
    • Osteopontin: role in immune regulation and stress responses
    • [51] Wang, K.X., Denhardt, D.T., Osteopontin: role in immune regulation and stress responses. Cytok. Growth Factor Rev. 19 (2008), 333–345.
    • (2008) Cytok. Growth Factor Rev. , vol.19 , pp. 333-345
    • Wang, K.X.1    Denhardt, D.T.2
  • 52
    • 84875373256 scopus 로고    scopus 로고
    • Osteopontin is increased in the bronchoalveolar lavage fluid and bronchial tissue of smoking asthmatics
    • [52] Samitas, K., Zervas, E., Xanthou, G., Panoutsakopoulou, V., Gaga, M., Osteopontin is increased in the bronchoalveolar lavage fluid and bronchial tissue of smoking asthmatics. Cytokine 61 (2013), 713–715.
    • (2013) Cytokine , vol.61 , pp. 713-715
    • Samitas, K.1    Zervas, E.2    Xanthou, G.3    Panoutsakopoulou, V.4    Gaga, M.5
  • 54
    • 33846658776 scopus 로고    scopus 로고
    • Emerging roles of MUC4 in cancer: a novel target for diagnosis and therapy
    • [54] Singh, A.P., Chaturvedi, P., Batra, S.K., Emerging roles of MUC4 in cancer: a novel target for diagnosis and therapy. Cancer Res. 67 (2007), 433–436.
    • (2007) Cancer Res. , vol.67 , pp. 433-436
    • Singh, A.P.1    Chaturvedi, P.2    Batra, S.K.3
  • 55
    • 79953320212 scopus 로고    scopus 로고
    • Modulation of cystatin A expression in human airway epithelium related to genotype, smoking, COPD, and lung cancer
    • [55] Butler, M.W., Fukui, T., Salit, J., Shaykhiev, R., Mezey, J.G., Hackett, N.R., Crystal, R.G., Modulation of cystatin A expression in human airway epithelium related to genotype, smoking, COPD, and lung cancer. Cancer Res. 71 (2011), 2572–2581.
    • (2011) Cancer Res. , vol.71 , pp. 2572-2581
    • Butler, M.W.1    Fukui, T.2    Salit, J.3    Shaykhiev, R.4    Mezey, J.G.5    Hackett, N.R.6    Crystal, R.G.7
  • 57
    • 84979656178 scopus 로고    scopus 로고
    • Shroom3 functions downstream of planar cell polarity to regulate myosin II distribution and cellular organization during neural tube closure
    • [57] McGreevy, E.M., Vijayraghavan, D., Davidson, L.A., Hildebrand, J.D., Shroom3 functions downstream of planar cell polarity to regulate myosin II distribution and cellular organization during neural tube closure. Biol. Open 4 (2015), 186–196.
    • (2015) Biol. Open , vol.4 , pp. 186-196
    • McGreevy, E.M.1    Vijayraghavan, D.2    Davidson, L.A.3    Hildebrand, J.D.4
  • 58
    • 0035971512 scopus 로고    scopus 로고
    • Aldehydic lipid peroxidation products derived from linoleic acid
    • [58] Spiteller, P., Kern, W., Reiner, J., Spiteller, G., Aldehydic lipid peroxidation products derived from linoleic acid. Biochim. Biophys. Acta 1531 (2001), 188–208.
    • (2001) Biochim. Biophys. Acta , vol.1531 , pp. 188-208
    • Spiteller, P.1    Kern, W.2    Reiner, J.3    Spiteller, G.4
  • 59
    • 80051694428 scopus 로고    scopus 로고
    • 4-Hydroperoxy-2-nonenal is not just an intermediate but a reactive molecule that covalently modifies proteins to generate unique intramolecular oxidation products
    • [59] Shimozu, Y., Hirano, K., Shibata, T., Shibata, N., Uchida, K., 4-Hydroperoxy-2-nonenal is not just an intermediate but a reactive molecule that covalently modifies proteins to generate unique intramolecular oxidation products. J. Biol. Chem. 286 (2011), 29313–29324.
    • (2011) J. Biol. Chem. , vol.286 , pp. 29313-29324
    • Shimozu, Y.1    Hirano, K.2    Shibata, T.3    Shibata, N.4    Uchida, K.5
  • 60
    • 84921478375 scopus 로고    scopus 로고
    • Airway metabolic anomalies in adolescents with bronchopulmonary dysplasia: new insights from the metabolomic approach
    • (e231)
    • [60] Carraro, S., Giordano, G., Pirillo, P., Maretti, M., Reniero, F., Cogo, P.E., Perilongo, G., Stocchero, M., Baraldi, E., Airway metabolic anomalies in adolescents with bronchopulmonary dysplasia: new insights from the metabolomic approach. J. Pediatr. 166 (2015), 234–239 (e231).
    • (2015) J. Pediatr. , vol.166 , pp. 234-239
    • Carraro, S.1    Giordano, G.2    Pirillo, P.3    Maretti, M.4    Reniero, F.5    Cogo, P.E.6    Perilongo, G.7    Stocchero, M.8    Baraldi, E.9
  • 62
    • 33847638020 scopus 로고    scopus 로고
    • Eicosanoids in inflammation: biosynthesis, pharmacology, and therapeutic frontiers
    • [62] Khanapure, S.P., Garvey, D.S., Janero, D.R., Letts, L.G., Eicosanoids in inflammation: biosynthesis, pharmacology, and therapeutic frontiers. Curr. Top. Med. Chem. 7 (2007), 311–340.
    • (2007) Curr. Top. Med. Chem. , vol.7 , pp. 311-340
    • Khanapure, S.P.1    Garvey, D.S.2    Janero, D.R.3    Letts, L.G.4
  • 63
    • 0035805539 scopus 로고    scopus 로고
    • Pathways of epoxyeicosatrienoic acid metabolism in endothelial cells. Implications for the vascular effects of soluble epoxide hydrolase inhibition
    • [63] Fang, X., Kaduce, T.L., Weintraub, N.L., Harmon, S., Teesch, L.M., Morisseau, C., Thompson, D.A., Hammock, B.D., Spector, A.A., Pathways of epoxyeicosatrienoic acid metabolism in endothelial cells. Implications for the vascular effects of soluble epoxide hydrolase inhibition. J. Biol. Chem. 276 (2001), 14867–14874.
    • (2001) J. Biol. Chem. , vol.276 , pp. 14867-14874
    • Fang, X.1    Kaduce, T.L.2    Weintraub, N.L.3    Harmon, S.4    Teesch, L.M.5    Morisseau, C.6    Thompson, D.A.7    Hammock, B.D.8    Spector, A.A.9
  • 66
    • 34250725999 scopus 로고    scopus 로고
    • Covalent adducts arising from the decomposition products of lipid hydroperoxides in the presence of cytochrome c
    • [66] Williams, M.V., Wishnok, J.S., Tannenbaum, S.R., Covalent adducts arising from the decomposition products of lipid hydroperoxides in the presence of cytochrome c. Chem. Res. Toxicol. 20 (2007), 767–775.
    • (2007) Chem. Res. Toxicol. , vol.20 , pp. 767-775
    • Williams, M.V.1    Wishnok, J.S.2    Tannenbaum, S.R.3


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