Exhaled breath measures of inflammation: Are they useful in neonatal chronic lung disease?

Archives of Disease in Childhood: Fetal and Neonatal Edition

Volumn 90, Issue 1, 2005, Pages

  Harrison, C M ^a   Andersen, C C ^a  

^a MERCY HOSPITAL FOR WOMEN   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON MONOXIDE; HYDROCARBON; NITRIC OXIDE; VOLATILE AGENT;

AIRWAY; ANALYTICAL ERROR; BREATH ANALYSIS; CHRONIC LUNG DISEASE; DIAGNOSTIC VALUE; EXHALATION; HUMAN; INFLAMMATION; NEWBORN; NONHUMAN; PREMATURITY; PRIORITY JOURNAL; REVIEW; RISK FACTOR; SAMPLING; SURVIVAL; TRACHEA; VALIDATION PROCESS;

BIOLOGICAL MARKERS; BREATH TESTS; CARBON MONOXIDE; CHRONIC DISEASE; HUMANS; HYDROCARBONS; INFANT, NEWBORN; INFANT, PREMATURE; INFANT, PREMATURE, DISEASES; LUNG DISEASES; NITRIC OXIDE; PNEUMONIA;

EID: 11144252646     PISSN: 13592998     EISSN: 14682052     Source Type: Journal    
DOI: 10.1136/adc.2003.040709     Document Type: Review

References (73)

1. Davis PG, Thorpe K, Roberts R, et al. Evaluating "old" definitions for the "new" bronchopulmonary dysplasia. J Pediatr 2002;140:555-60.
2. Jobe AH. The new BPD: an arrest of lung development. Pediatr Res 1999;46:641-3.
3. Van Marter LJ, Dammann O, Allred EN, et al. Chorioamnionitis, mechanical ventilation and postnatal sepsis as modulators of chronic lung disease in preterm infants. J Pediatr 2002;140:171-6.
4. Lauterbach R, Szymura-Oleksiak J. Nebulized pentoxifylline in successful treatment of five premature neonates with bronchopulmonary dysplasia. Eur J Pediatr 1999;158:607.
5. Davis JM, Parad RB, Michele T, et al. Pulmonary outcome at 1 year corrected age in premature infants treated at birth with recombinant human CuZn superoxide dismutase. Pediatrics 2003;111:469-76.
6. Russell GA, Cooke RW. Randomised controlled trial of allopurinol prophylaxis in very preterm infants. Arch Dis Child Fetal Neonatal Ed 1995;73:F27-31.
7. Halliday HL, Ehrenkranz RA, Doyle LW. Early postnatal (<96 hours) corticosteroids for preventing chronic lung disease in preterm infants (Cochrane Review). Cochrane Library. Issue 3. Oxford: Update Software, 2003.
8. Barrington KJ. Postnatal steroids and neurodevelopmental outcomes: a problem in the making. Pediatrics 2001;107:1425-6.
9. Massaro D, Massaro GD. Dexamethasone accelerates postnatal alveolar wall thinning and alters wall composition. Am J Physiol 1986;251:R218-24.
10. Kharitonov SA, Barnes PJ. Exhaled markers of pulmonary disease. Am J Respir Crit Care Med 2001;163:1693-722.
11. Ziegler JW, Ivy DD, Kinsella JP, et al. The role of nitric oxide, endothelin, and prostaglandins in the transition of the pulmonary circulation. Clin Perinatol 1995;22:387-403.
12. Nathan C. Nitric oxide as a secretory product of mammalian cells. FASEB J 1992;6:3051-64.
13. Kotecha S, Wilson L, Wangoo A, et al. Increase in Interluekin-1 and IL-6 in bronchoolveolar lavage fluid obtained from infants with chronic lung disease of prematurity. Pediatr Res 1996;40:250-6.
14. Vyas JR, Currie AE, Shuker DEG, et al. Concentration of nitric oxide products in bronchoalveolar fluid obtained from infants who develop chronic lung disease of prematurity. Arch Dis Child Fetal Edition 1999;81:F217-220.
15. Barnes PJ. Belvisi MG. Nitric oxide and lung disease. Thorax 1993;48:1034-43.
16. Olapade CO, Christon JA, Zakkar M, et al. Exhaled pentane and nitric oxide levels in patients with obstructive sleep apnea. Chest 1997;111:1500-4.
17. Brett SJ, Evans TW. Measurement of endogenous nitric oxide in the lungs of patients with the acute respiratory distress syndrome. Am J Respir Crit Care Med 1998;157:993-7.
18. Payne DNR. Nitric oxide in allergic airway inflammation. Curr Opin Allergy Clin Immunol 2003;3:133-7.
19. Aikio O, Pokela ML, Hallman M. Exhaled and nasal nitric oxide in mechanically ventilated preterm and term newborns. Acta Paediatr 2002;91:1078-86.
20. Williams O, Bhat RY, Cheeseman P, et al. Exhaled nitric oxide in chronically ventilated preterm infants. Arch Dis Child Fetal Ed 2004;89:F88-9.
21. Yoder MC, Chua R, Tepper R. Effect of dexamethasone on pulmonary inflammation and pulmonary function of ventilator-dependent infants with bronchopulmonary dysplasia. Am Rev Respir Dis 1991;143:1044-8.
22. Condorelli P, Shin HW, George SC. Characterizing airway and alveolar nitric oxide exchange during tidal breathing using a three-compartment model. J Appl Physiol, 2004 Jan 16 (Epub ahead of print).
23. Williams O, Rafferty GF, Hannam S, et al. Nasal and lower airway levels of nitric oxide in prematurely born infants. Early Hum Dev, 2003 May, 72:67-73.
24. American Thoracic Society. Recommendations for standardised procedures for the online and offline measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide in adults and children. Am J Respir Crit Care Med 1999;160:2104-117.
25. Silkoff PE, McClean PA, Slutsky AS, et al. Marked flow-dependence of exhaled nitric oxide using a new technique to exclude nasal nitric oxide. Am J Respir Crit Care Med 1997;155:260-7.
26. Artlich A, Busch T, Lewandowski K, et al. Exhaled nitric oxide in preterm infants. Respir Physiol 1998;114:195-200.
27. Sopienza MA, Kharitonov SA, Horvath I, et al. Effect of inhaled L-arginine on exhaled nitric oxide in normal and asthmatic subjects. Thorax 1998;53:172-5.
28. Kharitonov SA, Lubec G, Lubec B, et al. L-arginine increase exhaled nitric oxide in normal human subjects. Clin Sci 1995;88:135-9.
29. Stevenson DK, Vreman HJ, Wong RJ, et al. Carbon monoxide and bilirubin production in neonates. Semin Perinatol 2001;25:85-93.
30. Stevenson DK, Ostrander CR, Johnson JD. Effect of erythrocyte destruction on the pulmonary excretion rate of carbon monoxide in adult male Wistar rats. J Lab Clin Med 1979;94:649-54.
31. Stevenson DK, Vreman HJ, Oh W, et al. Bilirubin production in healthy term infants measured by carbon monoxide in breath. Clin Chem 1994;40:1934-9.
32. Stevenson DK, Fanaroff AA, Maisels MJ, et al. Prediction of hyperbilirubinemia in near-term infants. Pediatrics 2001;108:31-9.
33. Stevenson DK, Fanaroff AA, Maisels MJ, et al. Prediction of hyperbilirubinemia in near-term and term infants. J Perinatol 2001;21(suppl 1):S63-72.
34. Herschel M, Karrison T, Wen M, et al. Evaluation of the direct antiglobulin (Coombs') test for identifying newborns at risk for hemolysis as determined by end-tidal carbon monoxide concentration (ETCOc); and comparison of the Coombs' test with ETCOc for detecting significant jaundice. J Perinatol 2002;22:341-7.
35. Javier MC, Krauss A, Nesin M. Corrected end-tidal carbon monoxide closely correlates with the corrected reticulocyte count in coombs' test-positive term neonates. Pediatrics 2003;112:1333-7.
36. Zayasu K, Sekizawa K, Okinaga S, et al. Increased carbon monoxide in exhaled air of asthmatic patients. Am J Respir Crit Care Med 1997;156:1140-3.
37. Paredi P, Shah PL, Montuschi P, et al. Increased carbon monoxide in exhaled air of patients with cystic fibrosis. Thorax 1999;54:917-902.
38. Horvath I, Loukides S, Wodehouse T, et al. Elevated levels of carbon monoxide in bronchiectasis: a new marker of oxidative stress. Thorax 1998;53:867-70.
39. Antuni JD, Kharitonov SA, Hughes D, et al. Increase in exhaled carbon monoxide during exacerbations of cystic fibrosis. Thorax 2000;55:138-42.
40. Otterbein LE, Choi AM. Heme oxygenase: colors of defense against cellular stress. Am J Physiol Lung Cell Mol Physiol 2000;279:L1029-37.
41. Fanaroff A. Carbon monoxide predicts BPD. Southeastern Association of Neonatologists Meeting at Marco Island, May, 2003.
42. Shi Y, Pan F, Li H, et al. Plasma carbon monoxide significantly increased in paediatric sepsis syndrome. Arch Dis Child 2003;88:889-90.
43. Kharitinov SA, Paredi P, Barnes PJ. Methodological aspects of exhaled carbon monoxide measurements as a possible non-invasive marker of oxidative stress: influence of exhalation flow, breath holding and ambient air. Eur Respir J 1998;12:128s.
44. Zetterquist W, Marteus H, Johannesson M, et al. Exhaled carbon monoxide is not elevated in patients with asthma or cystic fibrosis. Eur Respir J 2002;20:92-9.
45. Paredi P, Kharitonov SA, Barnes PJ. Analysis of expired air for oxidation products. Am J Respir Crit Care Med 2002;166:531-7.
46. Kneepkens CM, Lepage G, Roy CC. The potential of the hydrocarbon breath test as a measure of lipid peroxidation. Free Radic Biol Med 1994;17:127-60.
47. Olapade CO, Christen JA, Zakkar M, et al. Exhaled pentane levels in acute asthma. Chest 1997;111:862-5.
48. Ondrula D, Nelson RL, Andrianopoulos G, et al. Quantitative determination of pentane in exhaled air correlates with colonic inflammation in the rat colitis model. Dis Colon Rectum 1993;36:457-62.
49. Humad S, Zarling E, Clapper M, et al. Breath pentane excretion as a marker of disease activity in rheumatoid arthritis. Free Radic Res Commun 1988;5:101-6.
50. Carpenter CT, Price PV, Christman BW. Exhaled breath condensate isoprostanes are elevated in patients with acute lung injury or ARDS. Chest 1998;114:1653-9.
51. Paredi P, Kharitinov SA, Leak D, et al. Elevated ethane, a marker of lipid peroxidation, is elevated in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2000;162:369-73.
52. Varsila E, Pitkanen O, Hallman M, et al. Immaturity-dependent free radical activity in premature infants. Pediatr Res 1994;36:55-9.
53. Buss IH, Darlow BA, Winterbourn CC. Elevated protein carbonyls and lipid peroxidation products correlating with myeloperoxidase in tracheal aspirates from premature infants. Pediatr Res 2000;47:640-5.
54. Jones HA, Clark RJ, Rhodes CG, et al. In vivo measurement of neutrophil activity in experimental lung inflammation. Am J Respir Crit Care Med 1994;149:1635-9.
55. Paredi P, Kharitonov SA, Barnes PJ. Elevation of exhaled ethane concentration in asthma. Am J Respir Crit Care Med 2000;162:1450-4.
56. Nycyk JA. Breath Pentane as a marker for lipid peroxidation and adverse outcome on preterm infants. Arch Dis Child Fetal Neonatal Ed 1998;79:F67-9.
57. Merritt TA, Stuard ID, Puccia J. Newborn tracheal aspirate cytology: classification during respiratory distress syndrome and bronchopulmonary dysplasia. J Pediatr 1981;98:949-56.
58. Grigg J, Arnon S, Chase A, et al. Inflammatory cells in the lungs of premature infants on the first day of life: perinatal risk factors and origin or cells. Arch Dis Child 1993;69:40-3.
59. Scott RJ, Peat D, Rhodes CA. Investigation of the fetal pulmonary inflammatory reaction in chorioamnionitis, using an in situ Y chromosome marker. Pediatr Pathol 1994;14:997-1003.
60. Pitkanen OM, Hallman M, Andersson SM. Determination of ethane and pentane in free oxygen radical induced lipid peroxidation. Lipids 1989;24:157-9.
61. Zarlin EJ, Clapper M. Technique for gas-chromatographic measurement of volatile alkanes from single-breath samples. Clin Clin 1987;33:140-1.
62. Springfield JR, Levitt MD. Pitfalls in the use of breath pentane measurements to assess lipid peroxidation. J Lipid Res 1994;35:1497-504.
63. Drury JA, Nycyk JA, Cooke RW. Pentane measurement in ventilated infants using a commercially available system. Free Radic Biol Med 1997;22:895-900.
64. Pitkanen OM, Hallman M, Andersson SM. Generation of free radicals in lipid emulsion used in porenteral nutrition. Pediatr Res 1991;29:56-9.
65. Wispe JR, Bell EF, Roberts RJ. Assessment of lipid peroxidation in newborn infants and rabbits by measurements of expired ethane and pentane: influence of parenteral lipid infusion. Pediatr Res 1985;19:374-9.
66. Pitkanen OM, Luukkainen P, Andersson S. Attenuated lipid peroxidation in preterm infants during subsequent doses of intravenous lipids. Biol Neonate. 2004;85: 184-7, Epub 24 Dec, 2003.
67. Freels JL, Robbins RA, Campbell SC. Exhaled breath condensate: the past, present, and future. Clinical Pulmonary Medicine 2003;10:263-8.
68. Carpagnano GE, Kharitonov SA, Resta O, et al. 8-Isoprostane, a marker of oxidative stress, is increased in exhaled breath condensate of patients with obstructive sleep apnea after night and is reduced by continuous positive airway pressure therapy. Chest 2003;124:1386-92.
69. Montuschi P, Corradi M, Ciabattoni G, et al. Increased 8-isoprostane, a marker of oxidative stress, in exhaled condensate of asthma patients. Am J Respir Crit Care Med 1999;160:216-20.
70. Baraldi E, Carraro S, Alinovi R, et al. Cysteinyl leukotrienes and 8-isoprostane in exhaled breath condensate of children with asthma exacerbations. Thorax 2003;58:505-9.
71. Gessner C, Hammerschmidt S, Kuhn H, et al. Exhaled breath condensate nitrite and its relation to tidal volume in acute lung injury. Chest 2003;124:1046-52.
72. Biernacki WA, Kharitonov SA, Barnes PJ. Increased leukotriene B4 and 8-isoprostane in exhaled breath condensate of patients with exacerbations of COPD. Thorax 2003;58:294-8.
73. Griese M, Latzin P, Beck J. A noninvasive method to collect nasally exhaled air condensate in humans of all ages. Eur J Clin Invest 2001;31:915-20.