Methotrexate reduces vaccine-specific immunoglobulin levels but not numbers of circulating antibody-producing B cells in rheumatoid arthritis after vaccination with a conjugate pneumococcal vaccine

Vaccine

Volumn 35, Issue 6, 2017, Pages 903-908

  Kapetanovic, Meliha C ^a   Nagel, Johanna ^a   Nordström, Inger ^b   Saxne, Tore ^a   Geborek, Pierre ^a   Rudin, Anna ^b  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Antibody responses; Circulating B cells; Methotrexate; Pneumococcal vaccination; Rheumatoid arthritis

Indexed keywords

IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G ANTIBODY; METHOTREXATE; PNEUMOCOCCUS VACCINE; 13-VALENT PNEUMOCOCCAL VACCINE; ANTIRHEUMATIC AGENT; BACTERIUM ANTIBODY; VACCINE;

ADULT; AGED; ANTIBODY BLOOD LEVEL; ANTIBODY RESPONSE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG RESPONSE; FEMALE; HUMAN; HUMAN CELL; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOGLOBULIN PRODUCING CELL; MALE; PLASMABLAST; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; VACCINATION; B LYMPHOCYTE; BIOSYNTHESIS; DRUG EFFECTS; ENZYME LINKED IMMUNOSPOT ASSAY; GROWTH, DEVELOPMENT AND AGING; IMMUNOLOGY; LYMPHOCYTE COUNT; MICROBIOLOGY; MIDDLE AGED; SEROTYPE; STREPTOCOCCUS PNEUMONIA; STREPTOCOCCUS PNEUMONIAE;

ADULT; AGED; ANTIBODIES, BACTERIAL; ANTIRHEUMATIC AGENTS; ARTHRITIS, RHEUMATOID; B-LYMPHOCYTES; ENZYME-LINKED IMMUNOSPOT ASSAY; FEMALE; HUMANS; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; LYMPHOCYTE COUNT; MALE; METHOTREXATE; MIDDLE AGED; PNEUMOCOCCAL VACCINES; PNEUMONIA, PNEUMOCOCCAL; SEROGROUP; STREPTOCOCCUS PNEUMONIAE; VACCINES, CONJUGATE;

EID: 85009200612     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2016.12.068     Document Type: Article

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