RBC deformability and amino acid concentrations after hypo-osmotic challenge may reflect chronic cell hydration status in healthy young men

Physiological Reports

Volumn 1, Issue 5, 2013, Pages

  Stookey, Jodi D ^a   Klein, Alexis ^b   Hamer, Janice ^a   Chi, Christine ^a   Higa, Annie ^c   Ng, Vivian ^c   Arieff, Allen ^d   Kuypers, Frans A ^a   Larkin, Sandra ^a   Perrier, Erica ^b   Lang, Florian ^e  

^a CHILDREN S HOSPITAL OAKLAND RESEARCH INSTITUTE   (United States)

^b Danone Research   (France)

^c CHILDREN S HOSPITAL OAKLAND   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Amino acid; Arginine; Biomarker; Cell hydration; Glutamate; Healthy adults; Histidine; RBC deformability; Water intake

Indexed keywords

AMINO ACID; ARGININE; DRINKING WATER; GLUTAMIC ACID; HISTIDINE; HYDROCORTISONE;

ADULT; AMINO ACID COMPOSITION; ARTICLE; BLOOD LEVEL; BODY MASS; CELL SWELLING; CHRONIC CELL HYDRATION; DIETARY INTAKE; ERYTHROCYTE DEFORMABILITY; ERYTHROCYTE FRAGILITY; FLUID INTAKE; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; HYPEROSMOTIC STRESS; HYPOOSMOTIC STRESS; MALE; MEAN CORPUSCULAR HEMOGLOBIN; NORMAL HUMAN; OSMOREGULATION; PHYSICAL ACTIVITY; RETICULOCYTE COUNT; SALIVA ANALYSIS; URINALYSIS; URINE LEVEL; WATER DEPRIVATION; YOUNG ADULT;

EID: 85009062694     PISSN: None     EISSN: 2051817X     Source Type: Journal    
DOI: 10.1002/phy2.117     Document Type: Article

References (55)

1. Arieff, A. 1986. Cerebral edema complicating nonketotic hyperosmolar coma. Miner. Electrolyte Metab. 12: 383–389.
2. Berneis, K., R. Ninnis, D. Haussinger, and U. Keller. 1999. Effects of hyper-and hypo-osmolality on whole body protein and glucose kinetics in humans. Am. J. Physiol. 276 (1 Pt 1): E188–E195.
3. Bratusch-Marrain, P. R., and R. A. DeFronzo. 1983. Impairment of insulin-mediated glucose metabolism by hyperosmolality in man. Diabetes 32: 1028–1034.
4. Buskirk, E. R., and S. M. Puhl. 1996. Body fluid balance: exercise and Sport. CRC Press, Boca Raton.
5. Chaplin, M. 2012. Water structure and science: intracellular water [Online]. Available at http: //www.lsbu.ac.uk/water/cell. html (accessed 16 April 2013).
6. Chen, G. F., and C. Baylis. 2010. In vivo renal arginine release is impaired throughout development of chronic kidney disease. Am. J. Physiol. Renal. Physiol. 298: F95–F102.
7. Chien, S. 1977. Principles and techniques for assessing erythrocyte deformability. Blood Cells 3: 71–99.
8. Clark, M. R., N. Mohandas, and S. B. Shohet. 1983. Osmotic gradient ektacytometry: comprehensive characterization of red cell volume and surface maintenance. Blood 61: 899–910.
9. DeFranceschi, L., D. Bachir, F. Galacteros, G. Tchernia, T. Cynober, S. Alper, et al. 1997. Oral magnesium supplements reduce erythrocyte dehydration in patients with sickle cell disease. J. Clin. Invest. 100: 1847–1852.
10. Dhanakoti, S. N., J. T. Brosnan, G. R. Herzberg, and M. E. Brosnan. 1990. Renal arginine synthesis: studies in vitro and in vivo. Am. J. Physiol. 259 (3 Pt 1): E437–E442.
11. Doi, M., I. Yamaoka, M. Nakayama, K. Sugahara, and F. Yoshizawa. 2007. Hypoglycemic effect of isoleucine involves increased muscle glucose uptake and whole body glucose oxidation and decreased hepatic gluconeogenesis. Am. J. Physiol. Endocrinol. Metab. 292: E1683–E1693.
12. Evan-Wong, L. A., and R. J. Davidson. 1983. Raised coulter mean corpuscular volume in diabetic ketoacidosis, and its underlying association with marked plasma hyperosmolarity. J. Clin. Pathol. 36: 334–336.
13. Forman, S., P. Crofton, H. Huang, T. Marshall, K. Fares, and N. McIntosh. 2012. The epidemiology of hypernatraemia in hospitalised children in Lothian: a 10-year study showing differences between dehydration, osmoregulatory dysfunction and salt poisoning. Arch. Dis. Child. 97: 502–507.
14. Ghandforoush-Sattari, M., S. Mashayekhi, C. V. Krishna, J. P. Thompson, and P. A. Routledge. 2010. Pharmacokinetics of oral taurine in healthy volunteers. J. Amino Acids 2010: 346237. doi: 10.4061/2010/346237
15. Grant, A. C. G., J. Thomson, V. A. Zammit, and D. B. Shennan. 2000. Volume-sensitive amino acid efflux from a pancreatic b-cell line. Mol. Cell. Endocrinol. 162: 203–210.
16. Greenleaf, J. E. 1992. Problem: thirst, drinking behavior, and involuntary dehydration. Med. Sci. Sports Exerc. 24: 645–656.
17. Gullans, S. R., J. D. Blumenfeld, J. A. Balschi, M. Kaleta, R. M. Brenner, C. W. Heilig, et al. 1988. Accumulation of major organic osmolytes in rat renal inner medulla in dehydration. Am. J. Physiol. 255 (4 Pt 2): F626–F634.
18. Häussinger, D., E. Roth, F. Lang, and W. Gerok. 1993. Cellular hydration state: an important determinant of protein catabolism in health and disease. Lancet 341: 1330–1332.
19. Holt, J. T., M. J. DeWandler, and D. A. Arvan. 1981. Spurious elevation of the electronically determined mean corpuscular volume and hematocrit caused by hyperglycemia. J. Clin. Pathol. 77: 561–567.
20. Horio, M., A. Yamauchi, Y. Matsuoka, T. Moriyama, M. Fukunaga, E. Imai, et al. 1999. Effect of hypertonic stress on amino acid levels and system A activity in rat peritoneal mesothelial cells. Perit. Dial. Int. 19: 124–130.
21. Hwang, G. S., J. Y. Yang, H. Ryu do, and T. H. Kwon. 2010. Metabolic profiling of kidney and urine in rats with lithium-induced nephrogenic diabetes insipidus by (1) H-NMR-based metabonomics. Am. J. Physiol. Renal. Physiol. 298: F461–F470.
22. Institute of Medicine of the National Academies (IOM). 2004. Dietary reference intakes: water, potassium, sodium, chloride, and sulfate. Panel on Dietary Reference Intakes for Electrolytes and Water. The National Academies Press, Washington, DC.
23. Jakicic, J. M., M. Marcus, K. I. Gallagher, C. Randall, E. Thomas, F. L. Goss, et al. 2004. Evaluation of the SenseWear Pro Armband to assess energy expenditure during exercise. Med. Sci. Sports Exerc. 36: 897–904.
24. Judelson, D. A., C. M. Maresh, L. M. Yamamoto, M. J. Farrell, L. E. Armstrong, W. J. Kraemer, et al. 2008. Effect of hydration state on resistance exercise-induced endocrine markers of anabolism, catabolism, and metabolism. J. Appl. Physiol. 105: 816–824.
25. Kirk, K., and J. Kirk. 1993. Volume-regulatory taurine release from a human lung cancer cell line, Evidence for amino acid transport via a volume-activated chloride channel. FEBS Lett. 336: 153–158.
26. Kjaer, A., P. J. Larsen, U. Knigge, and J. Warberg. 1995. Dehydration stimulates hypothalamic gene expression of histamine synthesis enzyme: importance for neuroendocrine regulation of vasopressin and oxytocin secretion. Endocrinology 136: 2189–2197.
27. Landry, D. W., and H. Bazari. 2011. Approach to the patient with renal disease. Chapter 116. Pp. 708–715 in L. Goldman and A. I. Schafer, eds. Goldman’s cecil medicine, 24th ed. Saunders Elsevier, Philadelphia, PA.
28. Lang, F., G. L. Busch, M. Ritter, H. Völkl, S. Waldegger, E. Gulbins, et al. 1998. Functional significance of cell volume regulatory mechanisms. Physiol. Rev. 78: 247–306.
29. Leaf, C. D., J. S. Wishnok, and S. R. Tannenbaum. 1989. L-Arginine is a precursor for nitrate biosynthesis in humans. Biochem. Biophys. Res. Commun. 163: 1032–1037.
30. Lue, L. F., C. Andrade, M. Sabbagh, and D. Walker. 2012. Is there inflammatory synergy in type II diabetes mellitus and Alzheimer’s disease? Int. J. Alzheimers Dis. 2012: 918680. doi: 10.1155/2012/91860
31. Manz, F. 2007. Hydration and disease. J. Am. Coll. Nutr. 26 (5 Suppl): 535S–541S.
32. Matthews, D. R., J. P. Hosker, A. S. Rudenski, B. A. Naylor, D. F. Treacher, and R. C. Turner. 1985. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28: 412–419.
33. McKenzie, M. A., J. E. Greenleaf, R. Looft-Wilson, and P. R. Barnes. 1999. Leucocytosis, thrombocytosis, and plasma osmolality during rest and exercise: an hypothesis. J. Physiol. Pharmacol. 50: 259–273.
34. Merson, S. J., R. J. Maughan, and S. M. Shirreffs. 2008. Rehydration with drinks differing in sodium concentration and recovery from moderate exercise-induced hypohydration in man. Eur. J. Appl. Physiol. 103: 585–594.
35. Nair, K. S., G. C. Ford, K. Ekberg, E. Fernqvist-Forbes, and J. Wahren. 1995. Protein dynamics in whole body and in splanchnic and leg tissues in type I diabetic patients. J. Clin. Invest. 95: 2926–2937.
36. Nielsen, B., J. R. S. Hales, S. Strange, N. J. Christensen, J. Warberg, and B. Saltin. 1993. Human circulatory and thermoregulatory adaptations with heat acclimation and exercise in a hot, dry environment. J. Physiol. 460: 467–485.
37. Nims, R. W., J. F. Darbyshire, J. E. Saavedra, D. Christodoulou, I. Hanbauer, G. W. Cox, et al. 1995. Colorimetric methods for the determination of nitric oxide concentration in neutral aqueous solutions. Methods 7: 48–54.
38. Nose, H., G. W. Mack, X. R. Shi, and E. R. Nadel. 1988. Role of osmolality and plasma volume during rehydration in humans. J. Appl. Physiol. 65: 325–331.
39. Ordaz, B., K. Tuz, and L. Ochoa, R. Lezama, C. Pena-Segura, and R. Franco. 2004. Osmolytes and mechanisms involved in regulatory volume decrease under conditions of sudden or gradual osmolarity decrease. Neurochem. Res. 29: 65–72.
40. Perucca, J., N. Bouby, P. Valeix, and L. Bankir. 2007. Sex difference in urine concentration across differing ages, sodium intake, and level of kidney disease. Am. J. Physiol. Regul. Integr. Comp. Physiol. 292: R700–R705.
41. Poortmans, J. R., and J. Vanderstraeten. 1994. Kidney function during exercise in healthy and diseased humans. An update. Sports Med. 18: 419–437.
42. Raff, H. 2009. Utility of salivary cortisol measurements in Cushing’s syndrome and adrenal insufficiency. J. Clin. Endocrinol. Metab. 94: 3647–3655.
43. Raj, D., M. Langford, S. Krueger, M. Shelton, and T. Welbourne. 2001. Regulatory responses to an oral d-glutamate load: formation of d-pyrrolidone carboxylic acid in humans. Am. J. Physiol. Endocrinol. Metab. 280: E214–E220.
44. Rhodes, J. D., O. Breck, R. Waagbo, E. Bjerkas, and J. Sanderson. 2010. N-acetylhistidine, a novel osmolyte in the lens of Atlantic salmon (Salmo salar L.). Am. J. Physiol. Regul. Intergr. Comp. Physiol. 299: R1075–R1081.
45. Shennan, D. B., and J. Thomson. 2004. Activation and inactivation of volume-sensitive taurine efflux from rat mammary gland. Mol. Cell. Biochem. 262: 111–118.
46. Shennan, D. B., J. Thomson, and I. F. Gow. 2006. Osmoregulation of taurine efflux from cultured human breast cancer cells: comparison with volume activated Cl efflux and regulation by ATP. Cell. Physiol. Biochem. 18: 113–122.
47. Sitton, N. G., J. S. Dixon, C. Astbury, R. J. Francis, H. A. Bird, and V. Wright. 1988. Kinetic investigations into the possible cause of low serum histidine in rheumatoid arthritis. Ann. Rheum. Dis. 47: 48–52.
48. Stancakova, A., M. Civelek, N. K. Saleem, P. Soininen, A. J. Kangas, H. Cederberg, et al. 2012. Hyperglycemia and a common variant of GCKR are associated with the levels of eight amino acids in 9, 369 Finnish men. Diabetes 61: 1895–1902.
49. Star, R. A. 1990. Southwestern internal medicine conference: hyperosmolar states. Am. J. Med. Sci. 300: 402–412.
50. Torres, V. E., J. J. Grantham, A. B. Chapman, M. Mrug, K. T. Bae, B. F. Jr King, et al. 2011. Potentially modifiable factors affecting the progression of autosomal dominant polycystic kidney disease. Clin. J. Am. Soc. Nephrol. 6: 640–647.
51. Tousoulis, D., A. M. Kampoli, C. Tentolouris, N. Papageorgiou, and C. Stefanadis. 2012. The role of nitric oxide on endothelial function. Curr. Vasc. Pharmacol. 10: 4–18.
52. Verbalis, J. 2003. Disorders of body water homeostasis. Best Pract. Res. Clin. Endocrinol. Metab. 17: 471–503.
53. Watanabe, M., M. E. Suliman, A. R. Qureshi, E. Garcia-Lopez, P. Barany, O. Heimburger, et al. 2008. Consequences of low plasma histidine in chronic kidney disease patients: association with inflammation, oxidative stress, and mortality. Am. J. Clin. Nutr. 87: 1860–1866.
54. Wong, L. S., M. S. Johnson, L. B. Sandberg, and B. L. Taylor. 1995. Amino acid efflux in response to chemotactic and osmotic signals in Bacillus subtilis. J. Bacteriol. 177: 4342–4349.
55. Yancey, P. H., M. E. Clark, S. C. Hand, R. D. Bowlus, and G. N. Somero. 1982. Living with water stress: evolution of osmolyte systems. Science 217: 1214–1222.