Huntingtin-Mediated Multipolar-Bipolar Transition of Newborn Cortical Neurons Is Critical for Their Postnatal Neuronal Morphology

Neuron

Volumn 93, Issue 1, 2017, Pages 99-114

  Barnat, Monia ^a,b   Le Friec, Julien ^a,b   Benstaali, Caroline ^a,b   Humbert, Sandrine ^a,b  

^a UNIV GRENOBLE ALPES   (France)

^b INSERM   (France)

Author keywords

cortical development; huntingtin; Huntington disease; migration; multipolar bipolar transition; N cadherin; neuronal morphology; polarization; RAB11; trafficking

Indexed keywords

HUNTINGTIN; NERVE CELL ADHESION MOLECULE; RAB11 PROTEIN; CADHERIN; CDH2 PROTEIN, MOUSE; HTT PROTEIN, MOUSE; PEPTIDE; POLYGLUTAMINE; RAB PROTEIN;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EMBRYO; FEMALE; HUNTINGTON CHOREA; IN VIVO STUDY; LIMIT OF QUANTITATION; MOUSE; MULTIPOLAR BIPOLAR TRANSITION; NEOCORTEX; NERVE PROJECTION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; ANIMAL; BRAIN CORTEX; CELL MOTION; CELL POLARITY; CYTOLOGY; DISEASE MODEL; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; NERVE CELL; PROTEIN TRANSPORT;

ANIMALS; ANIMALS, NEWBORN; CADHERINS; CELL MOVEMENT; CELL POLARITY; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; HUNTINGTIN PROTEIN; HUNTINGTON DISEASE; MICE; NEOCORTEX; NEURONS; PEPTIDES; PROTEIN TRANSPORT; RAB GTP-BINDING PROTEINS;

EID: 85009060712     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2016.11.035     Document Type: Article

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