Impact of genotyping errors on statistical power of association tests in genomic analyses: A case study

Genetic Epidemiology

Volumn 41, Issue 2, 2017, Pages 152-162

  Hou, Lin ^a,b   Sun, Ning ^a,b   Mane, Shrikant ^c   Sayward, Fred ^a,c   Rajeevan, Nallakkandi ^a,c   Cheung, Kei Hoi ^a,c   Cho, Kelly ^d,e   Pyarajan, Saiju ^d,e   Aslan, Mihaela ^a,c   Miller, Perry ^a,c   Harvey, Philip D ^f,g   Gaziano, J Michael ^d,e   Concato, John ^a,c   Zhao, Hongyu ^a,b  

^a VA CONNECTICUT HEALTHCARE SYSTEM   (United States)

^b YALE UNIVERSITY   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d VA BOSTON HEALTHCARE SYSTEM   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

^f VETERANS AFFAIRS MEDICAL CENTER   (United States)

^g UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

genome wide association test; genotyping; genotyping error; sequencing; statistical power

Indexed keywords

NUCLEOTIDE; GENETIC MARKER;

ACCURACY; ARTICLE; DISEASE ASSOCIATION; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOME ANALYSIS; GENOTYPE; GENOTYPING ERROR; MATHEMATICAL COMPUTING; NEXT GENERATION SEQUENCING; PROCESS OPTIMIZATION; QUALITY CONTROL; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL BIAS; STATISTICAL PARAMETERS; STATISTICAL POWER; ALGORITHM; BIPOLAR DISORDER; CASE CONTROL STUDY; COMPARATIVE STUDY; GENETIC ASSOCIATION STUDY; GENETIC MARKER; GENETICS; GENOMICS; HIGH THROUGHPUT SEQUENCING; HUMAN; PROCEDURES; SCHIZOPHRENIA; STANDARDS; STATISTICAL ANALYSIS;

ALGORITHMS; BIPOLAR DISORDER; CASE-CONTROL STUDIES; DATA INTERPRETATION, STATISTICAL; GENETIC ASSOCIATION STUDIES; GENETIC MARKERS; GENOMICS; GENOTYPE; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; POLYMORPHISM, SINGLE NUCLEOTIDE; QUALITY CONTROL; SCHIZOPHRENIA;

EID: 85008932269     PISSN: 07410395     EISSN: 10982272     Source Type: Journal    
DOI: 10.1002/gepi.22027     Document Type: Article

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